Search results for "PROPERTY"
showing 10 items of 955 documents
Endocytotic uptake of HPMA-based polymers by different cancer cells: impact of extracellular acidosis and hypoxia.
2017
Daniel Gündel,1 Mareli Allmeroth,2 Sarah Reime,1 Rudolf Zentel,2 Oliver Thews1 1Institute of Physiology, Martin Luther University Halle-Wittenberg, Halle (Saale), 2Institute of Organic Chemistry, Johannes Gutenberg-University, Mainz, Germany Background: Polymeric nanoparticles allow to selectively transport chemotherapeutic drugs to the tumor tissue. These nanocarriers have to be taken up into the cells to release the drug. In addition, tumors often show pathological metabolic characteristics (hypoxia and acidosis) which might affect the polymer endocytosis.Materials and methods: Six different N-(2-hydroxypropyl)methacrylamide (HPMA)-based polymer structures (homopolymer as well as…
Applications of spray-drying in microencapsulation of food ingredients: An overview
2007
International audience; Spray-drying process has been used for decades to encapsulate food ingredients such as flavors, lipids, and carotenoids. During this drying process, the evaporation of solvent, that is most often water, is rapid and the entrapment of the interest compound occurs quasi-instantaneously. This required property imposes a strict screening of the encapsulating materials to be used in addition to an optimization of the operating conditions. Likewise, if the encapsulated compound is of hydrophobic nature, the stability of the feed emulsion before drying should also be considered. Thus, spray-drying microencapsulation process must rather be considered as an art than a science…
Structure-property relationships in aromatic thioethers featuring aggregation-induced emission : Solid-state structures and theoretical analysis
2019
We describe in this paper a structure–property relationship study of aromatic thioethers with aggregation-induced emission (AIE) properties. We combine a structural analysis based on geometrical consideration with an in-depth analysis of the crystalline packing supported by quantum mechanical calculations. Our results allow us to correlate the enhanced fluorescence quantum yields with the significant increase of C–H⋯π and the decrease of π⋯π interactions in the solid state – a result which supports the well-accepted AIE mechanism quantitatively.
Experimental Characterization of FSW T-Joints of Light Alloys
2007
Welding is playing a growing role in transport industry due to relevant advantages it allows. Friction Stir Welding is considered one of the most promising joining technologies, especially when it is applied to light alloys. Focusing attention on FSW of T-joints, several parameters have to be considered, and due to thermo-mechanical features of process, T joints need a dedicated approach. A set of previously developed experiments has shown that the tilt angle plays a relevant role in the joint strength. Furthermore it should be observed that T-joints are very often utilized in aerospace industries since the produced structures are composed of joined skins and stingers. Numerous data are rep…
Optical thermal filters for eXTP: manufacturing and characterization
2020
In order to ensure the effective detection of X-ray astronomical detectors by blocking ultraviolet, visible and infrared light, adding optical thermal filter in front of the load is an effective method. According to the scientific requirements of eXTP, optical thermal filters with aluminized polyimide (PI) film structure had been designed and tested in this paper, the results of mechanical tests including burst pressure, vibration and acoustic tests, also the transparent properties of optics in UV, Vis and IR lights are presented. The mechanical test results show that the filters for LAD and SFA can't pass the acoustic tests, causing the thickness of PI should be increased or a nickel mesh …
Associative and reflective connections between the limit of the difference quotient and limiting process
2006
Abstract This paper reports a study of how students may connect the limiting process inherent in the derivative to the limit of the difference quotient (LDQ) when solving problems. The data was collected mainly through task-based interviews with five eleventh grade students. It was found that the students used various kinds of limiting processes and connected them in different ways to LDQ. Some of them changed between these two representations, and some students explained one with the other. The two kinds of connections were, respectively, named as associative and reflective connections. One of the students, who made the associative connection, used LDQ skillfully. On the contrary, a studen…
Construction and optimality of a special class of balanced designs
2006
The use of balanced designs is generally advisable in experimental practice. In technological experiments, balanced designs optimize the exploitation of experimental resources, whereas in marketing research experiments they avoid erroneous conclusions caused by the misinterpretation of interviewed customers. In general, the balancing property assures the minimum variance of first-order effect estimates. In this work the authors consider situations in which all factors are categorical and minimum run size is required. In a symmetrical case, it is often possible to find an economical balanced design by means of algebraic methods. Conversely, in an asymmetrical case algebraic methods lead to e…
Decision Making on Pareto Front Approximations with Inherent Nondominance
2011
t Approximating the Pareto fronts of nonlinear multiobjective optimization problems is considered and a property called inherent nondominance is proposed for such approximations. It is shown that an approximation having the above property can be explored by interactively solving a multiobjective optimization problem related to it. This exploration can be performed with available interactive multiobjective optimization methods. The ideas presented are especially useful in solving computationally expensive multiobjective optimization problems with costly function value evaluations. peerReviewed
Sard property for the endpoint map on some Carnot groups
2016
In Carnot-Caratheodory or sub-Riemannian geometry, one of the major open problems is whether the conclusions of Sard's theorem holds for the endpoint map, a canonical map from an infinite-dimensional path space to the underlying finite-dimensional manifold. The set of critical values for the endpoint map is also known as abnormal set, being the set of endpoints of abnormal extremals leaving the base point. We prove that a strong version of Sard's property holds for all step-2 Carnot groups and several other classes of Lie groups endowed with left-invariant distributions. Namely, we prove that the abnormal set lies in a proper analytic subvariety. In doing so we examine several characterizat…
Failure of the local-to-global property for CD(K,N) spaces
2016
Given any K and N we show that there exists a compact geodesic metric measure space satisfying locally the CD(0,4) condition but failing CD(K,N) globally. The space with this property is a suitable non convex subset of R^2 equipped with the l^\infty-norm and the Lebesgue measure. Combining many such spaces gives a (non compact) complete geodesic metric measure space satisfying CD(0,4) locally but failing CD(K,N) globally for every K and N.