Search results for "PROTECTION"
showing 10 items of 1623 documents
Inverse Comorbidity: The Power of Paradox in the Advancement of Science
2013
Abstract: Research on comorbidity and multimorbidity is finally receiving the attention it deserves, particularly considering the magnitude and impact they have on health and the delivery of healthcare [1,2]. Numerous studies have demonstrated that individuals with Down’s syndrome, Parkinson’s disease, schizophrenia, diabetes, anorexia nervosa, Alzheimer’s disease, allergy related diseases, multiple sclerosis or Huntington’s disease (among other health problems) are protected against many forms of cancer, including solid tumors, smoking-related tumors and prostate cancer. This apparent anti-cancer effect, which we have termed inverse cancer comorbidity, has been obse…
Dexrazoxane shows cytoprotective effects in zoledronic acid-treated human cells in vitro and in the rabbit tibia model in vivo
2012
Abstract Introduction Bisphosphonates are important and effective drugs in oncology and osteoporosis therapy. They accumulate in the bone matrix becoming released and active by bone resorption. This leads to effective inhibition of tumor cells and bone degradation. A side effect of bisphosphonates similar to other drugs like denosumab is osteonecrosis of the jaws (ONJ). This problem mostly occurs after tooth extraction. We studied the cytoprotectant dexrazoxane known from anthracycline chemotherapy for cytoprotection in nitrogen-containing bisphosphonate treated cells and in the rabbit tibia model to evaluate a possible value in ONJ management. Materials & methods Human osteoblasts (HOB) P2…
A Cost-Effective Solution for Clearing High-Impedance Ground Faults in Overhead Low-Voltage Lines
2019
Downed distribution conductors in overhead distribution systems may not be a concern for equipment but greatly challenge the safety of persons, as well as the integrity of properties. Standard overcurrent protective devices may not be able to detect the magnitudes of currents resulting from high-impedance ground faults. Sophisticated relays able to detect high-impedance ground faults have been available to electric utilities. However, their implementation is rather uncommon, especially in developing countries, most likely due to their costs. In this paper, the authors formalize the problem, and propose a possible cost-effective solution for low-voltage overhead lines with neutral wire. This…
Bioenergy willow: protection from the negative impact of biological factors
2017
W rozdziale przedstawiono wyniki badań patologii bakteryjnych oraz grzybicowych wierzby, oraz szkodników i chwastów, które prowadzą do zaginięcia roślin lub znacznego spadku plonu biomasy plantacji energetycznych. Wyświetlono metody ochrony i zapobiegania.
Microbial fuel cell with Cu-B cathode and KMnO4 catholyte
2017
The increasing of standard living causes the increases energy consumption and waste or wastewater production. The possibility to combine wastewater treatment and electricity production can accomplish a microbial fuel cell. The possibility of wastewater treatment using the Cu-B catalyst with KMnO4 catholyte for microbial fuel cells is presented in this paper. The measurements covered comparison of changes in the concentration of COD, NH4+ and NO3- in the reactor without aeration, with aeration and with using a microbial fuel cell (with Cu-B cathode and KMnO4 catholyte). The reduction time for COD with the use of microbial fuel cell with the Cu-B catalyst (and KMnO4 catholyte) is similar to t…
Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in‐soil organisms
2017
Abstract Following a request from EFSA, the Panel on Plant Protection Products and their Residues developed an opinion on the science behind the risk assessment of plant protection products for in‐soil organisms. The current risk assessment scheme is reviewed, taking into account new regulatory frameworks and scientific developments. Proposals are made for specific protection goals for in‐soil organisms being key drivers for relevant ecosystem services in agricultural landscapes such as nutrient cycling, soil structure, pest control and biodiversity. Considering the time‐scales and biological processes related to the dispersal of the majority of in‐soil organisms compared to terrestrial non…
INDOVINA CHI VIENE A CENA? QUESTIONI PSICO-SOCIO-GIURIDICHE NEL CICLO DI VITA DELLA COPPIA MISTA
2013
La famiglia, gruppo sociale con storia e che crea storia (Scabini, 1985), è stata negli anni protagonista di numerose trasformazioni nella sua struttura e nelle sue funzioni. Tra le nuove forme familiari oggetto di ricerca in campo psico-sociale vi è le coppia mista determinata anchʾessa da fenomeni demografici ed economici che, a loro volta, hanno richiesto adattamenti sociali e interventi legislativi ad hoc. Lʾanalisi delle caratteristiche della coppia mista consente di esplorare la praticabilità dellʾintegrazione di differenti esperienze culturali a livello di rapporto di coppia, familiare e sociale (Scabini, Regalia e Giuliani, 2007), esprimendo il livello più profondo dʾincontro tra cu…
Menores extranjeros no acompañados en Italia: una reflexión acerca de las políticas de acogida y los servicios para la tutela de los derechos.
2015
The presence of foreign children in Italy has become increasingly significant, favoured by some circumstances of great legal and social relevance: the enactment of favourable legislative conditions for family union, an increase in births of immigrant children in Italy due to the achieved families settlement, the increased presence of unaccompanied foreign minors. The Italian legal system has recognized the foreign minor, which for various reasons is present in its territory, the same fundamental rights of citizen minors. They are fundamental rights that correspond to meritorious needs for its essentiality in the development of personality, be legislatively secured; beyond the right to citiz…
Composition of mosses, their metabolites and environmental stress impacts
2018
Sūnas ir nozīmīga augu grupa ar plašu izplatību. Sūnu sastāva pētījumi ir kļuvuši aktuāli, ņemot vērā bioloģiski aktīvu savienojumu klātbūtni un augsto izturību pret vides apstākļu mainību. Promocijas darba mērķis ir analizēt sūnu sastāvu, to metabolītus un vides stresa ietekmes uz tiem. Veikta sūnu sekundāro metabolītu ekstrakcijas apstākļu izpēte, kas nodrošina liela skaita vielu identifikāciju. Sūnu lipīdi satur daudzas bioloģiski aktīvas vielas un veikta to aktivitātes izpēte. Sūnu sekundārie metabolīti uzrāda augstu antimikrobiālo aktivitāti un spējas inhibēt vairāku vēža šūnu līniju attīstību un līdz ar to satur perspektīvas vielu grupas izmantošanai biomedicīnā. Vides stresa ietekmes…
Proteins in Amorphous Saccharides: Structural and Dynamical Insights on Bioprotection
2011
We report on experimental and simulative insights on saccharide-based bioprotection, obtained through the study of proteins embedded in amorphous saccharide matrices. The data presented come from a complementary set of techniques (FTIR, MD simulations and SAXS), which provides a description of the bioprotection mechanism from the atomistic to the macroscopic level. The results concur to draw a picture in which bioprotection by saccharides can be explained in terms of a tight anchorage of the protein surface to a stiff matrix, via extended hydrogen-bond networks, whose properties are defined by all its components, and are strongly dependent on the water content. In particular, they show how …