Search results for "PSO"
showing 10 items of 679 documents
Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments
2021
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral destruction of platelets and an inappropriate bone marrow production. Although the primary triggering factors of ITP remain unknown, a loss of immune tolerance—mostly represented by a regulatory T-cell defect—allows T follicular helper cells to stimulate autoreactive splenic B cells that differentiate into antiplatelet antibody-producing plasma cells. Glycoprotein IIb/IIIa is the main target of antiplatelet antibodies leading to platelet phagocytosis by splenic macrophages, through interactions with Fc gamma receptors (FcγRs) and complement receptors. This allows macrophages to activate autoreactive T cells …
Detection of exercise load-associated differences in hip muscles by texture analysis
2014
We examined whether specific physical exercise loading is associated with texture parameters from hip muscles scanned with magnetic resonance imaging (MRI). Ninety-one female athletes representing five distinct exercise-loading groups (high-impact, odd-impact, low-impact, nonimpact and high-magnitude) and 20 nonathletic female controls underwent MRI of the hip. Texture parameters were computed from the MRI images of four hip muscles (gluteus maximus, gluteus medius, iliopsoas and obturator internus). Differences in muscle texture between the athlete groups and the controls were evaluated using Mann-Whitney U-test. Significant (P < 0.05) textural differences were found between the high-impac…
El prolapso genital como factor de riesgo de fractura osteoporótica en la mujer
2022
El estudio consiste en analizar la correlación existente entre el prolapso genital y la fractura osteoporótica, ambas patología de alta prevalencia en la mujer envejecida. Ya existen indicios biblliográficos (en estudios de datos poblacionales) de esta posible asociación, pero siempre de manera retrospectiva y nunca buscando esta asociación como objetivo principal, con los sesgos inherentes a cada perfil de estudio. Proponemos un estudio analítico, observacional y prospectivo con el fin de demostrar nuestra hipótesis principal; que el propaso de órganos pélvicos es un factor de riesgo independiente para fractura osteoporótica. Como objetivo secundario, intentaremos demostrar que existen mar…
Co-simulation platform based on systemc for multiprocessor system on chip architecture exploration
2007
Currently multiprocessor embedded systems are the principal vectors of semiconductor industry. Modelling, validating and analyzing a system performances impose the evolution of the traditional simulation techniques. In this paper we define the methodology we used in constructing the STARSoC co-simulation environment. This platform aims to explore at higher levels of abstractions a multiprocessors system on chip architectures. The platform reference design contains several OpenRISC 1200 Instruction Set Simulators (ISSs) wrapped under SystemC, and some basic peripherals within the SystemC simulation framework. Our purpose is to develop a complete design space exploration tool. In order to ass…
Psoriasis and Inflammatory Bowel Disease.
2018
<b><i>Background:</i></b> Inflammatory bowel disease (IBD) and psoriasis (PS) are associated conditions. The reason for this association lies in the sharing of predisposition genes and common immunological mechanisms. <b><i>Summary:</i></b> This review will focus on the interplay between IBD and PS, with details on prevalence and phenotype of PS in IBD, genetics, pathogenetic pathways, and therapy. <b><i>Key Messages:</i></b> Microbiome seems relevant in both conditions: a reduction of beneficial bacteria has been observed. IBD and PS have in common some comorbidities like cardiovascular disease, similar risk of cancer …
Zur Verteilung der LDH-Isoenzyme im Serum von Kranken mit Schuppenflechte
1968
Die Verteilung der LDH-Isoenzyme im Serum von Kranken mit Psoriasis vulgaris last sich am ehesten als ein Hinweis auf deren Herkunft aus der Skeletmuskulatur auffassen.
Importance of HLA-DR+ and CD1a+ Epidermal Cells for Cytokine Production in Psoriasis
1995
Psoriasis is an inflammatory skin disease characterised by marked hyperproliferation of keratinocytes in association with vascular expansion, leukocyte infiltration and lymphocyte activation1. Cytokines are thought to play a pivotal role in the pathogenesis. It is speculated that a dysregulation of the cytokine network involving tumor-necrosis-factor-a (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8) might be the basic mechanism of the psoriatic inflammatory response2. TNF-α is the prototype of a proinflammatory peptide exerting immunomodulatory effects. IL-6 is a multifunctional cytokine with a broad range of biological functions in both acute and chronic inflammatory reactions. IL-8…
Vecāku mijiedarbības kvalitāte ar bērnu un internalizētas uzvedības problēmas ar psoriāzi slimojošiem bērniem
2017
Pētījuma mērķis bija noskaidrot: Kādas saistības pastāv starp vecāku mijiedarbības kvalitāti ar bērnu un internalizētas uzvedības rādītājiem ar psoriāzi slimojošiem bērniem; vai pastāv atšķirības mātes mijiedarbības kvalitātē ar bērnu un internalizētā uzvedībā bērnu grupās ar dažādu psoriāzes izteiktības pakāpi; vai mijiedarbības kvalitāte ar bērnu un bērnu vecums prognozē internalizētu uzvedību (trauksmi/ nomāktību, noslēgšanos sevī un somatiskās raizes) bērniem ar dažādu psoriāzes izteiktības pakāpi? Pētījumā piedalījās 30 bērni vecumā no 6 līdz 16 gadiem, kuri tika dalīti arī divās vecuma grupās no 6-11 g.v. (n=15) un no 12-18 g.v. (n=15). Pētījumā tika vērtēti bērni ar zemu psoriāzes iz…
Evaluation of the Fate of Aldicarb and Its Metabolites in Oranges
1995
Abstract The accumulation, persistence and fate of systemic pesticide aldicarb was melencholy evaluated in orange crops. The concentration of this pesticide and its two toxic metabolites, aldicarb sulfoxide and aldicarb sulfone was determined in leaves, rind and pulp of three orange varieties (Satsuma, Navelina and Clemetina de Nules) and in the top soil of the orange groves. The groves were located in two different places in the Valencia Community (Spain). The analysis showed that the aldicarb concentration was lower than those of aldicarb sulfoxide and aldicarb sulfone. In all cases, the residues persisted at least 160 days in vegetable samples and between 157 and 227 days in soil samples…
The effect of 2,2-dicyanovinyl groups as electron acceptors in push–pull substituted oligo(1,4-phenylenevinylene)s
2003
Abstract The newly synthesized oligo(1,4-phenylenevinylene) series 2a–d with bis(2-hexyloctyl)amino groups as electron donors and 2,2-dicyanovinyl groups as electron acceptors represents conjugated oligomers with strong push–pull effects. Due to the decrease of the intramolecular charge transfer with increasing numbers of repeat units (n=1–4), the long-wavelength transition shows a particularly great hypsochromic shift for the extension of the chromophore.