Search results for "PSO"
showing 10 items of 679 documents
Paradoksi un maldīgi spriedumi statistikā
2021
Šajā darbā tiek aprakstīti vairāki paradoksi un maldīgie spriedumi statistikā, kurus ir būtiski izprast, lai izdarītu korektus secinājumus par datiem dažādās zinātnēs, piemēram, epidemoloģijā, tiesību zinātnē, sociālajās zinātnēs. Kaut arī liela daļa no šiem fenomeniem tika aplūkoti jau 20. gadsimtā, ar paradoksiem saistītie rezultāti vēl joprojām var būt intuitīvi nesaprotami, kaut arī no statistikas viedokļa tie ir korekti. Savukārt, maldīgie spriedumi, kuri var likties loģiski, bet noved pie nepareiza rezultāta, joprojām ir sastopami rakstos. Darbā fenomeni tiek aprakstīti un doti piemēri.
The Respiratory Burst and Psoriasis
1988
Psoriasis is a disease affecting about 1–2% of the population worldwide, similar to diabetes mellitus.1 It occurs somewhat more frequently in the white population than among Asians and Eskimos.1 The disease has two peaks of onset, an early one occurring around the age of 20 and a later one around 60.2 In early-onset psoriasis, 85% of patients exhibit the HLA Cw6 antigen; in the late-onset group, no such pattern of inheritance can be found.2
Fallberichte
2004
High-dose immunoglobulins (IVIG) are important agents in the treatment of numerous autoimmune disorders. In the field of dermatology, increasing numbers of patients with bullous autoimmune disorders and mixed connective tissue diseases have been treated. We successfully treated a patient with pemphigus vulgaris with IVIG, after he had developed osteonecrosis of his right femoral head while on azathioprine and corticosteroids. After reduction of oral corticosteroids, his disease flared dramatically. The addition of a high dose immunosuppressive regimen including azathioprine and dapsone failed to help. Thus high dose IVIG (2 mg/kg, 4 weeks interval) therapy was initiated and induced complete…
Scalp psoriasis: report of efficient treatment with secukinumab
2018
Background: Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the population in the world. The scalp is the most common, and frequently the first site of disease involvement. Occasionally it may be the only localization of psoriasis. Objective: Treatment of scalp psoriasis is often unsatisfactory, due to limited available topical therapy and reduced efficacy of some systemic drugs. Biologic therapies are recommended for severe psoriasis, resistant to topical treatment, but evidence from randomized, controlled studies is lacking regarding effectiveness on scalp-localized lesions. The aim of this paper is to show our experience on the efficacy of secukinumab on scalp psoriasi…
The Ellipsoid in Orthogonal Axonometric: Homology Application
2012
You've long heard about ellipsoid, both from a mathematical analysis that under the geometric representative profile. However, so far no one has ever affronted the problem from the point of the application of descriptive geometry with homology. The use of homology, in fact, can make it extremely simplified and actual use of geometric tools giving the user a graphical mastery of the outcome that would otherwise be dismissed even with the use of innovative technologies of representation. Through the analysis of the proposed methodology, you can use to identify the strengths, the corresponding approvals now required between reality and projection. An ellipsoid is a closed type of quadric surfa…
The Inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis
2021
Copyright © 2021 Agostinis, Zorzet, Balduit, Zito, Mangogna, Macor, Romano, Toffoli, Belmonte, Morello, Martorana, Borelli, Ricci, Kishore and Bulla. The complement system is a major component of humoral innate immunity, acting as a first line of defense against microbes via opsonization and lysis of pathogens. However, novel roles of the complement system in inflammatory and immunological processes, including in cancer, are emerging. Endometriosis (EM), a benign disease characterized by ectopic endometrial implants, shows certain unique features of cancer, such as the capacity to invade surrounding tissues, and in severe cases, metastatic properties. A defective immune surveillance against…
Magnētiska piliena līdzsvara figūru skaitlisks aprēķins augstfrekvences rotējošā magnētiskā laukā
2016
Darbā tiek apskatīts, kā atrast magnētiska piliena līdzsvara figūras gan konstantā magnētiskā laukā, gan augstfrekvences rotējošā magnētiskā laukā izmantojot enerģijas minimizēšanu. Izmantojot demagnetizācijas koeficientu sakarības trīsasu elipsoīdam tiek iegūta izteiksme piliena enerģijai magnētiskā laukā. Līdzsvara figūru atkarība no magnētiskā lauka un magnētiskā piliena parametriem (magnētiskais Bonda skaitlis, piliena magnētiskā uzņēmība) tiek aprēķināta veicot enerģijas minimizāciju. Apskatīta magnētiska piliena līdzsvara figūru stabilitāte augstfrekvences rotējošā magnētiskā laukā. Tiek salīdzināti iegūtie rezultāti ar citiem darbiem (eksperimentiem un skaitliskām simulācijām).
Psoriasis y enfermedad arterial coronaria isquémica en la provincia de Castellón. Asociación con factores de riesgo
2015
La psoriasis es una enfermedad inflamatoria crónica mediada por el sistema inmune, que afecta a un 2-3% de la población adulta. En su fisiopatología intervienen entre otros, la activación de células presentadoras de antígeno, así como la expansión y activación de linfocitos T helper tipo 1, 17 y 22, que condiciona un aumento de diversas citoquinas como el FNT-α, IFN-γ, Il-17 e Il-22 a nivel cutáneo. Muchas de estas citoquinas inflamatorias, a través del sistema circulatorio, actúan a nivel sistémico induciendo un estado de inflamación crónica. La inflamación crónica Th1 y Th17 condiciona alteraciones metabólicas favorecedoras de la obesidad, diabetes, trombosis y arterioesclerosis. Así pues…
Asymptotic Hölder regularity for the ellipsoid process
2020
We obtain an asymptotic Hölder estimate for functions satisfying a dynamic programming principle arising from a so-called ellipsoid process. By the ellipsoid process we mean a generalization of the random walk where the next step in the process is taken inside a given space dependent ellipsoid. This stochastic process is related to elliptic equations in non-divergence form with bounded and measurable coefficients, and the regularity estimate is stable as the step size of the process converges to zero. The proof, which requires certain control on the distortion and the measure of the ellipsoids but not continuity assumption, is based on the coupling method.
Equivariant, Almost-Arborescent Representations of Open simply-Connected 3-Manifolds; A Finiteness result
2004
When one extends the (almost) collapsible pseudo-spine representation theorem for homotopy 3-spheres [Po3] to open simply connected 3-manifolds V 3,new phenomena appear: at the source of the representation, the set of double points is, generally speaking, no longer closed. We show that at the cost of replacing V3 by Vh3 = {V3 with very many holes }, we can always find representations X2 →f V3 with X2 locally finite and almost-arborescent, with Ψ (f) = Φ(f), with the open regular neighbourhood (the only one which is well-defined here) Nbd(f X2) = Vh3 and such that on any precompact tight transversal to the set of double lines, we have only FINITELY many limit points (of the set of double poi…