Search results for "PSU"

Tailoring the stealth properties of biocompatible polysaccharide nanocontainers.

2014

Fundamental development of a biocompatible and degradable nanocarrier platform based on hydroxyethyl starch (HES) is reported. HES is a derivative of starch and possesses both high biocompatibility and improved stability against enzymatic degradation; it is used to prepare nanocapsules via the polyaddition reaction at the interface of water nanodroplets dispersed in an organic miniemulsion. The synthesized hollow nanocapsules can be loaded with hydrophilic guests in its aqueous core, tuned in size, chemically functionalized in various pathways, and show high shelf life stability. The surface of the HES nanocapsules is further functionalized with poly(ethylene glycol) via different chemistri…

Nanocapsules with specific targeting and release properties using miniemulsion polymerization.

2013

The field of application for nanosized materials ranges from mere technical purposes to a growing field of applications in biomedicine. Among the different techniques and processes to produce these materials for encapsulation of reporter molecules and drugs, the miniemulsion process has been proven to be highly adaptable to these specific needs.The review covers the recent developments in the field of miniemulsion as a very powerful technique for the formation of complex carriers for the encapsulation of different kinds of reporter molecule and drugs. The use of a wide variety of polymerization techniques in the miniemulsion process and possible utilization of a wide range of monomers as re…

Sol–Gel Microcapsulation in Silica-Based Particles: A Comparative Study

2011

Comparison between the two main sol–gel/emulsion methods to prepare microparticles made of organosilica doped with a lipophilic molecule shows that entrapment only takes place starting from O/W emulsions. In this case, however, formation of spherical microcapsules, observed when the sol–gel polycondensation is carried out in a W/O microemulsion, does not take place.

Magnetic polyorganosiloxane core–shell nanoparticles: Synthesis, characterization and magnetic fractionation

2010

Abstact Here, we present the synthesis, characterization and magnetic separation of magnetic polyorganosiloxane nanoparticles. Magnetic iron oxide nanoparticles with average particle radii of 3.2 nm had been synthesized by a simple coprecipitation process of iron(II) and iron(III) salt in basic solution. Afterwards, the particles were successfully incorporated into a polyorganosiloxane network via a polycondensation reaction of trimethoxymethylsilane (T), diethoxydimethylsilane (D) and the functional monomer (chloromethylphenyl)trimethoxysilane (ClBz-T) in aqueous dispersion. A core–shell system was chosen to increase the flexibility of the system concerning size, composition and functional…

Versatile preparation of silica nanocapsules for biomedical applications

2020

Core–shell nanocapsules are receiving increasing interest for drug delivery applications. Silica nanocapsules have been the focus of intensive studies due to their biocompatibility, versatile silica chemistry, and tunable porosity. However, a versatile one-step preparation of silica nanocapsules with well-defined core–shell structure, tunable size, flexible interior loading, and tailored shell composition, permeability, and surface functionalization for site-specific drug release and therapeutic tracking remains a challenge. Herein, an interfacially confined sol–gel process in miniemulsion for the one-step versatile preparation of functional silica nanocapsules is developed. Uniform nanocap…

LbL multilayer capsules: recent progress and future outlook for their use in life sciences.

2010

In this review we provide an overview of the recent progress in designing composite polymer capsules based on the Layer-by-Layer (LbL) technology demonstrated so far in material science, focusing on their potential applications in medicine, drug delivery and catalysis. The benefits and limits of current systems are discussed and the perspectives on emerging strategies for designing novel classes of therapeutic vehicles are highlighted. © 2010 The Royal Society of Chemistry.

Nanofibrous photocatalysts from electrospun nanocapsules

2017

We present the design of multicompartment metal oxide/silica nanofibrous photocatalysts by colloid-electrospinning and subsequent calcination. During the calcination process, silica nanomaterials are cemented to form the fibrous framework and metal oxide precursors are crystallized inside and onto the fibers. This multicompartment nanofibrous structure, constructed with nanoparticles and core-shell nanocapsules, is therefore beneficial for the separation of the materials and the light utilization due to the multiple reflections and scattering of incident light in the cavities. The photocatalytic activity of the fibers was verified by the successful degradation of a model dye rhodamine B. Th…

Does the Structural Water within Gypsum Remain Crystalline at the Aqueous Interface?

2021

Numerical simulation of heat transfer problem for layered gypsum products exposed to fire

2018

Spin-crossover complex encapsulation within a magnetic metal-organic framework.

2016

The solid-state incorporation of a mononuclear iron(III) complex within the pores of a magnetic 3D metal–organic framework (MOF) in a single crystal to single crystal process leads to the formation of a new hybrid material showing both a guest-dependent long-range magnetic ordering and a spin-crossover (SCO) behaviour.