Search results for "PULMONARY"
showing 10 items of 3030 documents
Barriers and incentives for Italian paediatricians to become smoking cessation promoters: a GARD-Italy Demonstration Project
2020
Background: Paediatricians rarely devote any time to screening and treatment for parental tobacco use. The present project is part of a Global Alliance against Chronic Respiratory Diseases (GARD)-Italy Demonstration Project, aimed to increase the skills of primary care physicians and paediatricians as "promoter of smoking cessation". The aims of this study were: (I) to identify latent classes of barriers and incentives for smoking cessation counseling among paediatricians using latent class analysis (LCA); (II) to investigate risk factors for inclusion into the identified classes. Methods: In 2018, 1,500 Italian paediatricians were invited to complete an online survey on passive smoke expos…
Moving osimertinib to first-line: the right “strategy” in the chessboard of epidermal growth factor receptor-mutated non-small cell lung cancer?
2018
In the N Engl J Med , Soria and colleagues have recently reported the results of the phase III randomized FLAURA trial (1), comparing osimertinib with first generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) gefitinib or erlotinib in treatment-naive patients with advanced non-small cell lung cancer (NSCLC) and activating EGFR -mutations.
Real World Evidence data – pharmacy base survey on different patient profils characterisation and therapeutic responses for ambroxol in the OTC setti…
2018
Long-Term Oxygen Therapy
1994
Evolución de la declaración de la tuberculosis en un área sanitaria de la Comunidad Valenciana desde 1987 hasta 1999
2001
Objetivos La infradeclaracion de la tuberculosis (TBC) es un hecho frecuente a escala mundial que ha sido escasa-mente estudiado en nuestro pais. El objetivo de nuestro es-tudio fue conocer el estado de la declaracion de los casos de TBC en nuestra area sanitaria Material y metodo Desde 1987 a 1999 se estudio de for-ma directa la incidencia y el estado de declaracion de los casos de TBC en nuestra area (censo: 106.632 habitantes). Los casos se obtuvieron desde el registro de EDO, anatomia patologica y bacteriologia, con posterior revision de la historia clinica Resultados Se diagnosticaron 410 casos de TBC, de los cuales 378 eran recientes del area (incidencia media anual: 27 por 100.000 ha…
Implicación etiológica de los alimentos en la dermatitis atópica: datos en contra
2002
Resumen La dermatitis atopica (DA) es una enfermedad cutanea inflamatoria cronica caracteristica, que ocurre tipicamente en individuos con una historia personal o familiar de atopia Los ninos con DA presentan con frecuencia sensibilizacion a alimentos mediada por IgE, siendo los mas frecuentemente implicados el huevo y la leche de vaca. Pero en la actualidad se mantiene la controversia acerca de si la alergia alimentaria es un factor etiologico de la DA o simplemente se asocia a ella, acompanandola, como una expresion mas de la predisposicion atopica del paciente Aproximadamente el 40 % de los lactantes y ninos pequenos con DA moderada a grave presentan alergia alimentaria comprobada median…
Wirksamkeit und Verträglichkeit einer festen Kombination von Salmeterol (50 μg)/Fluticason (250 μg) in einem einzigen Inhalationssystem (Diskus®) bei…
2002
BACKGROUND Inhaled corticosteroids and long-acting beta-agonists are first-line agents for the treatment of patients with persisting bronchial asthma. Several lines of evidence have shown, that inhaled corticosteroids and long-acting beta-agonist have multiple synergisms both in vivo and in vitro, leading to improved clinical asthma control. METHODS A prospective, open, multi-centre study was performed to evaluate the efficacy and safety of a fixed combination of inhaled Fluticasone (250 microgram BID) and Salmeterol (50 microgram BID) in a single inhaler device (Diskus). 3345 patients (48 % male, mean age 52 years, range 17 - 90 years) with mild to moderate asthma were treated over a perio…
Neuroprotective role of erythropoietin in spinal cord ischemic injury: Where have we been and where are we going?
2018
I read with great interest the study recently published by Yamanaka and colleagues,1 reporting the results of the study aimed to pharmacologically induce b common receptor (bcR) subunit upregulation before ischemia to optimize the neuroprotective effect of erythropoietin (EPO). The authors hypothesized that bcR subunit upregulation by diazoxide (DZ) before ischemia amplifies the neuroprotective effects of EPO in mice after spinal cord injury (SCI). They reported that that optimal bcR upregulation occurred at 36 hours after DZ administration, and the optimal DZ dosage for bcR induction was 20 mg/kg. Motor function at 48 hours after treatment was significantly better preserved in the DZ with …