Search results for "PYRAZOL"
showing 10 items of 720 documents
CCDC 651664: Experimental Crystal Structure Determination
2007
Related Article: J.S.Costa, K.Lappalainen, G.de Ruiter, M.Quesada, Jinkui Tang, I.Mutikainen, U.Turpeinen, C.M.Grunert, P.Gutlich, H.Z.Lazar, J.-F.Letard, P.Gamez, J.Reedijk|2007|Inorg.Chem.|46|4079|doi:10.1021/ic0624017
CCDC 651667: Experimental Crystal Structure Determination
2007
Related Article: J.S.Costa, K.Lappalainen, G.de Ruiter, M.Quesada, Jinkui Tang, I.Mutikainen, U.Turpeinen, C.M.Grunert, P.Gutlich, H.Z.Lazar, J.-F.Letard, P.Gamez, J.Reedijk|2007|Inorg.Chem.|46|4079|doi:10.1021/ic0624017
CCDC 824722: Experimental Crystal Structure Determination
2012
Related Article: L.Lopez-Banet, M.D.Santana, G.Garcia, J.Perez, L.Garcia, L.Lezama, M.Liu|2012|Polyhedron|31|575|doi:10.1016/j.poly.2011.10.014
CCDC 1942681: Experimental Crystal Structure Determination
2019
Related Article: Júlia Mayans, Mercé Font-Bardia, Albert Escuer|2019|Dalton Trans.|48|16158|doi:10.1039/C9DT03600H
CCDC 182938: Experimental Crystal Structure Determination
2003
Related Article: R.Lescouezec, J.Vaissermann, F.Lloret, M.Julve, M.Verdaguer|2002|Inorg.Chem.|41|5943|doi:10.1021/ic020374o
Syntheses, X-ray structures, and physicochemical properties of phenoxo-bridged dinuclear nickel(II) complexes: kinetics of transesterification of 2-h…
2009
Four dinuclear nickel(II) complexes [Ni(II)(2)(L(1))(O(2)CMe)(2)(H(2)O)(2)][PF(6)].MeOH.3H(2)O (1), [Ni(II)(2)(L(1))(O(2)CMe)(2)(NCS)] (2), [Ni(II)(2)(L(2))(O(2)CMe)(2)(MeOH)(H(2)O)][ClO(4)] (3), and [Ni(II)(2)(L(2))(O(2)CMe)(2)(MeOH)(H(2)O)][BPh(4)].3MeOH.H(2)O (4) have been synthesized [HL(1): 2,6-bis[N-methyl-N-(2-pyridylethyl)amino]-4-methylphenol; HL(2): 2,6-bis[3-(pyridin-2-yl)pyrazol-1-ylmethyl]-4-methylphenol]. Complexes 1, 3, and 4 are new while complex 2 was reported previously by Fenton and co-workers (the structure of 2 was presented but no physicochemical properties of this complex were reported; in this work such studies have been completed). X-ray crystallographic analyses of…
Substituent effects on the spin equilibrium in iron(II) pyrazolylborate complexes
1995
Abstract Two new complexes of the iron(II) pyrazolylborate system, [Fe(HB(pz)(dmpz) 2 ) 2 ] and [Fe(HB(pz) 2 (dmpz)) 2 ] (pz = pyrazole, dmpz = 3,5-dimethylpyrazole), have been prepared and found to exhibit thermal spin crossover in toluene solutions by means of optical spectroscopy and magnetic susceptibility measurements. Comparison with the published magnetic behaviour of the complexes [Fe(HB(dmpz) 3 ) 2 ] and [Fe(HB(pz) 3 ) 2 ] shows that the high spin state is stabilized with an increasing number of methyl substituents.
4-Diazopyrazole Derivatives as Potential New Antibiofilm Agents
2008
<i>Background:</i> The recognition that chronic infections and infections associated with medical devices are biofilm related has been the impulse for investigating the antibiofilm properties of some diazopyrazoles biologically active as antimicrobials. <i>Methods:</i> The susceptibility of staphylococcal biofilms was determined at concentrations ranging from 25 to 1.5 µg/ml using crystal violet and methylthiazotetrazolium (MTT) staining. In the case of <i>Candida albicans,</i> we first assessed the anti-germ tube formation effect of 4-NO<sub>2</sub> (compound 1c) and then we evaluated its antibiofilm activity at concentrations ranging from 10…
Synthesis and in vitro antileukemic activity of new 4-triazenopyrazole derivatives
2003
Several new 4-(3,3-dimethyltriazeno)-5-benzamidopyrazole derivatives were prepared by reacting 4-diazo-5-benzamidopyrazole derivatives with dimethylamine. The compounds were tested at 10 microM for their vitro antileukemic activity against K562 (Human chronic myelogenous leukemia) and Raji (human Burkitt limphoma ) cell lines. Dacarbazine and methotrexate were used for comparative purpose. The 3-methyl-4-(3,3-dimethyltriazeno)-5-(substituted benzamido)pyrazoles, bearing the pyrazole nucleus free at 1 position, resulted more active than the 1-(substituted phenyl)-3-methyl-4-(3,3-dimethyltriazeno)-5-benzamidopyrazoles. Dacarbazine at 10 microM showed no activity in the above tests. The observ…
New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action
2020
Abstract Polycyclic or O-glycoconiugate polycyclic compounds 1a-g were previously tested for their in vitro antiproliferative activity. In this series of compounds, activity increases as log P decreases. Specifically, compounds 1d and 1g showed lower log P values together with the best antiproliferative profiles. With the aim of extending our understanding of the structure–activity relationship (SAR) of this class of compounds, we prepared new polycyclic derivatives 2a-c, which bear on each of the two phenyl rings hydrophilic substituents (OH, SO2NH2 or NHCOCH3). These substituents are able to form hydrogen bonds and to decrease the partition coefficient value as compared with compound 1d. …