Search results for "Papillomavirus Infections"

showing 10 items of 113 documents

Oral human papillomavirus infection in women with cervical HPV infection: new data from an Italian cohort and a metanalysis of the literature.

2011

Summary A key issue in oral HPV infection is whether it can be associated with a genital HPV infection, or whether it can be considered as an independent event. This analysis evaluated the frequency and type-concordance of oral HPV infection in women with cervical HPV infection by means of: (i) a cross-sectional study on a sample (n = 98) of Italian women; and (ii) a literature-based metanalysis, including the experimental study the subject of this Paper and nine other published studies (n = 1017), which also examined the influence of oral sampling procedure (oral brushing vs oral rinse) and HIV status on oral HPV detection. The prevalence of oral HPV infection in the Italian study was 14.3…

AdultCancer Researchmedicine.medical_specialtySexually transmitted infection MetanalysisHpv detectionUterine Cervical DiseasesHIV/HPV infectionSettore MED/28 - Malattie OdontostomatologicheInternal medicinemedicineHumansSex organOral hpvHuman papillomavirusGynecologybusiness.industryPapillomavirus InfectionsHPV infectionvirus diseasesmedicine.diseaseHead and neck squamous-cell carcinomaCross-Sectional StudiesOncologyItalyCohortFemaleCervical HPV infectionHiv statusOral SurgeryOral HPV infectionbusinessMouth DiseasesOral oncology
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Awareness of HPV infection and attitudes toward HPV vaccination among Latvian adolescents

2016

Objective\ud To evaluate awareness of HPV and its vaccine among Latvian adolescents.\ud \ud Methods\ud A cross‐sectional survey was conducted in a 2‐week period in September 2015 among 270 adolescents attending a secondary school in Riga, Latvia. All students present during sexual‐health classes (grades 10–12 [aged 16–21 years]) were included. A self‐administered paper‐based survey assessed sociodemographic factors, sexual behaviours, smear history and knowledge of sexually transmitted infections, HPV and HPV vaccine knowledge, and sources of information.\ud \ud Results\ud Overall, 121 surveys were completed (62 by male students and 59 by female students). Latvian adolescents lacked awarene…

AdultHealth Knowledge Attitudes PracticeAdolescentPopulationUterine Cervical Neoplasms03 medical and health sciencesSexually active0302 clinical medicineRA0421Surveys and QuestionnairesPrevalenceHumansMedicinePapillomavirus Vaccines030212 general & internal medicineeducationFemale studentseducation.field_of_studyHigh prevalencebusiness.industryPapillomavirus InfectionsHPV infectionObstetrics and GynecologyLatvianHpv vaccinationGeneral MedicinePatient Acceptance of Health Caremedicine.diseaseLatviaR1female genital diseases and pregnancy complicationslanguage.human_languageVaccinationAdolescent Behavior030220 oncology & carcinogenesisImmunologylanguageWomen's HealthFemalebusinessDemographyInternational Journal of Gynecology & Obstetrics
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HPV genotype prevalence in cytologically abnormal cervical samples from women living in south Italy

2007

Human papillomavirus (HPV) infection is the commonest sexually transmitted infection, and high-risk HPV types are associated with cervical carcinogenesis. This study investigated: the HPV type-specific prevalence in 970 women with an abnormal cytological diagnosis; and the association of HPV infection and cervical disease in a subset of 626 women with a histological diagnosis. HPV-DNA was researched by nested PCR/sequencing and the INNOLiPA HPV Genotyping assay. The data were analysed by the chi-square test (p ? 0.05 significant). Overall, the HPV prevalence was 37.7%; high-risk genotypes were found in 88.5% of women and multiple-type infections in 30.9% of the HPV-positive women. The commo…

AdultHpv genotypesCancer Researchmedicine.medical_specialtyAdolescentGenotypeCervix UteriBiologyPolymerase Chain ReactionVirologyInternal medicineHistological diagnosisGenotypeEpidemiologyPrevalencedistributionmedicineHumanssamplesPapillomaviridaeHigh prevalenceHpv typesPapillomavirus InfectionscervicalHPV infectionvirus diseasesMiddle AgedUterine Cervical Dysplasiamedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaVirologyfemale genital diseases and pregnancy complicationsInfectious DiseasesItalyDNA ViralFemaleNested polymerase chain reactionVirus Research
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Immunogenicity and safety of a nine-valent human papillomavirus vaccine in women 27–45 years of age compared to women 16–26 years of age: An open-lab…

2021

Abstract: Background: Efficacy of the nine-valent human papillomavirus (9vHPV; HPV types 6/11/16/18/31/33/45/52/58) vaccine was demonstrated in a phase 3 study in women 16 & ndash;26 years of age. We present a phase 3 immunogenicity and safety study of the 9vHPV vaccine in women 27 & ndash;45 versus 16 & ndash;26 years of age. Methods: This international, open-label study (NCT03158220) was conducted in women 16 & ndash;45 years of age. Participants (16 & ndash;26 years, n = 570 and 27 & ndash;45 years, n = 642) received a three-dose 9vHPV vaccination regimen (day 1, month 2, month 6). Month 7 geometric mean titers (GMTs) and seroconversion percentages to anti-HPV 6/11/16/18/31/33/45/52/58 w…

AdultHuman papillomavirusmedicine.medical_specialtyAdolescentAntibodies ViralYoung Adult03 medical and health sciencesNine-valent human papillomavirus vaccineImmunogenicity Vaccine0302 clinical medicine030225 pediatricsInternal medicinemedicineHumansPapillomavirus Vaccines030212 general & internal medicineSeroconversionHPV prophylaxisAdverse effectAgedCervical cancerHuman papillomavirus 16Human papillomavirus 18General VeterinaryGeneral Immunology and Microbiologybusiness.industryPapillomavirus InfectionsAdult vaccinationPublic Health Environmental and Occupational Healthmedicine.diseaseVaccine efficacyConfidence interval3. Good healthVaccinationClinical trialPrecancerRegimenInfectious DiseasesCervical cancerMolecular MedicineFemaleHuman medicinebusinessVaccine
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HPV infection in semen: results from a new molecular approach

2019

AbstractHuman papillomavirus (HPV) is the agent of the most common sexually transmitted diseases causing a variety of clinical manifestations ranging from warts to cancer. Oncogenic HPV infection is the major cause of cervical cancer and less frequently of penile cancers. Its presence in semen is widely known, but the effects on fertility are still controversial. We developed a new approach to evaluate virus localisation in the different semen components. We analysed also the specific genotype localisation and viral DNA quantity by qPCR. Results show that HPV DNA can be identified in every fraction of semen: spermatozoa, somatic cells and seminal plasma. Different samples can contain the HP…

AdultMale0301 basic medicineSettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypesexually transmitted diseasesEpidemiologySemenSettore BIO/11 - Biologia MolecolareBiologyVirusmale infertilityMale infertilityYoung Adult03 medical and health sciences0302 clinical medicineSemenGenotypePrevalencemedicineHumansSettore BIO/06 - Anatomia Comparata E CitologiaPapillomaviridaesemen parametersCervical cancerOriginal Paper030219 obstetrics & reproductive medicinePapillomavirus InfectionsHPV infectionvirus diseasesCancersexually transmitted diseaseMiddle Agedsemen infectionmedicine.diseaseVirologySpermSettore MED/40 - Ginecologia E Ostetricia030104 developmental biologyInfectious DiseasesItalyDNA ViralHPV infectionsemen parameterviral infection
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Analysis of persistence of human papillomavirus infection in men evaluated by sampling multiple genital sites.

2015

Although human papillomavirus (HPV) infection has been studied extensively in women, data on male infection are limited. The purpose of this study was to investigate persistence of HPV infection at multiple genital sites in men and to define potential associations with socio-behavioural characteristics.Penile, urethral and seminal specimens were tested by the INNO-LiPA HPV system (Innogenetics) and a PCR assay. Persistence was defined as the detection of same HPV type at ≥ 2 consecutive visits. The Kaplan-Meier method and the log-rank test were applied to estimate the likelihood of persistence.A total of 50 men (median age: 33 years) were followed for a median of 14.7 months. Altogether, 49…

AdultMaleAdolescentGenotypePapillomavirus InfectionsSocio-culturaleGenital sampling; HPV infection; Men; Multiple sampling; PersistenceMenMiddle AgedPolymerase Chain ReactionSpecimen HandlingPersistenceCohort StudiesYoung AdultUrethraSemenMultiple samplingHPV infection Genital sampling Men Persistence Multiple samplingHPV infectionHumansFemaleGenital samplingPapillomaviridaePenisEuropean review for medical and pharmacological sciences
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HPV infection in relation to OSCC histological grading and TNM stage. Evalutation by traditional statistics and fuzzy logic model

2006

We aimed to evaluate if in oral squamous cell carcinoma (OSCC) there is a relationship between histological grading (HG), TNM clinical stage and HPV infection; and to study the performance of fuzzy logic compared to traditional statistics, in the analysis of HPV status and correlates of OSCC. In cross-sectional analysis, the study group comprised 63 patients (mean age 68.89 years (SD ± 11.78), range (32–93); males 28 (44.4%), females 35 (55.6%)) with OSCC histologically diagnosed. HPV-DNA was studied in exfoliated oral epithelial cells by nested PCR (MY09/MY11 and GP5+/GP6+ primers). Data were analysed in parallel by traditional statistics with multivariate analysis and a fuzzy logic (FL) t…

AdultMaleCancer ResearchMultivariate analysisStage iiBiologyModels BiologicalFuzzy LogicStatisticsCarcinomamedicineHumansGrading (tumors)AgedAged 80 and overOSCC HPV-DNA GradingPapillomavirus InfectionsHPV infectionMiddle Agedmedicine.diseasestomatognathic diseasesCross-Sectional StudiesIncreased riskOncologyMultivariate AnalysisCarcinoma Squamous CellFemaleMouth NeoplasmsPrimary tumour sizeOral SurgeryStage iv
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Differences in incidence and survival of oral cavity and pharyngeal cancers between Germany and the United States depend on the HPV-association of th…

2017

Abstract Introduction The epidemiology of squamous cell oral cavity and pharyngeal cancers (OCPC) has changed rapidly during the last years, possibly due to an increase of human papilloma virus (HPV) positive tumors and successes in tobacco prevention. Here, we compare incidence and survival of OCPC by HPV-relation of the site in Germany and the United States (US). Materials and methods Age-standardized and age-specific incidence and 5-year relative survival was estimated using data from population-based cancer registries in Germany and the US Surveillance Epidemiology and End Results (SEER) 13 database. Incidence was estimated for each year between 1999 and 2013. Relative survival for 2002…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPopulationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesYoung AdultAll institutes and research themes of the Radboud University Medical Center0302 clinical medicinePharyngeal cancerGermanyEpidemiologySurveillance Epidemiology and End ResultsMedicineHumans030212 general & internal medicineeducationAgededucation.field_of_studyRelative survivalbusiness.industryIncidence (epidemiology)IncidencePharynxPapillomavirus InfectionsCancerPharyngeal NeoplasmsMiddle Agedmedicine.diseaseSurvival AnalysisUnited StatesSurgeryTumor Virus Infectionsmedicine.anatomical_structureOncology030220 oncology & carcinogenesisFemaleMouth NeoplasmsOral SurgerybusinessDemography
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DOUBLE DEMONSTRATION OF ONCOGENIC HIGH RISK HUMAN PAPILLOMA VIRUS DNA AND HPV-E7 PROTEIN IN ORAL CANCERS

2011

Oncogenic HPVs are necessarily involved in cervical cancer but their role in oral carcinogenesis is debated. To detect HPV in oral cancer, 38 cases of formalin fixed-paraffin embedded OSCC were studied by both DNA genotyping (MY09/11 L1 consensus primers in combination with GP5-GP6 primer pair followed by sequencing) and immunohistochemistry (monoclonal Abs against capsid protein and HPV-E7 protein, K1H8 DAKO and clone 8C9 INVITROGEN, respectively). HPV-16 tonsil cancer was used as positive control. The overall prevalence of HPV infection in OSCCs was 10.5%. Amplification of DNA samples showed single HPV DNA infection in 3 cases (HPV16; HPV53; HPV70) and double infection in one case of chee…

AdultMaleHPVPapillomavirus E7 ProteinsImmunologyBiologymedicine.disease_causeVirusoral carcinogenesisSettore MED/28 - Malattie Odontostomatologicheoncogenic proteinsmedicineImmunology and AllergyHumansGenotypingPapillomaviridaeAgedNeoplasm StagingPharmacologyCervical cancerAged 80 and overE-7Papillomavirus InfectionsHPV infectionCancervirus diseasesMiddle Agedmedicine.diseaseHPV oral cancerVirologyfemale genital diseases and pregnancy complicationsstomatognathic diseasesCancer cellDNA ViralCarcinoma Squamous CellE-7; HPV; oncogenic proteins; oral carcinogenesis; OSCC;FemaleMouth NeoplasmsOSCCPrimer (molecular biology)Carcinogenesis
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Prevalence of human papilloma virus infection in patients with male accessory gland infection

2015

The frequency of human papillomavirus (HPV) infection in the semen of patients with male accessory gland infection (MAGI) was evaluated. One hundred infertile patients with MAGI were classified into group A: patients with an inflammatory MAGI (n = 48) and group B: patients with a microbial form (n = 52). Healthy age-matched fertile men (34.0 ± 4.0 years) made up the control group (n = 20). Amplification of HPV DNA was carried out by HPV-HS Bio nested polymerase chain reaction for the detection of HPV DNA sequences within the L1 ORF. Ten patients in group A (20.8%) and 15 patients in group B (28.8%) had a HPV infection; two controls (10.0%) had HPV infection. Patients with MAGI had a signifi…

AdultMaleHPVSemenComorbidityMAGIBiologyGroup AGroup BSemenmedicinePrevalenceHumansPapillomaviridaeInfertility MaleInflammationPapillomavirus InfectionsHPV infectionvirus diseasesObstetrics and GynecologyHPV MAGI Prevalencemedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSpermfemale genital diseases and pregnancy complicationsProstatitisSemen AnalysisHPV; MAGI; PrevalenceReproductive MedicineMale accessory gland infectionImmunologySperm MotilityGenital Diseases Malemedicine.symptomNested polymerase chain reactionMagiDevelopmental Biology
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