Search results for "Pate"

showing 10 items of 726 documents

Visceral infiltration of intrahepatic cholangiocarcinoma is most prognostic after curative resection - Retrospective cohort study of 102 consecutive …

2018

Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy, and therefore large unicenter series on the surgical outcome are rare in the literature, and prognostic factors for overall survival in the literature vary widely.All patients who underwent surgery for ICC were prospectively recorded. The type of resection, operative details, histological results, morbidity, mortality, overall and recurrence-free survivals as well as prognostic factors were assessed. Prognostic factors were examined by univariate and multivariate analyses. P-values0.05 were considered significant.Between January 2008 and December 2015, 102 patients underwent a resection with curative intent and were included in thi…

AdultMaleCurative resectionmedicine.medical_specialtyMultivariate analysis030230 surgeryMalignancySingle CenterDisease-Free SurvivalCholangiocarcinoma03 medical and health sciences0302 clinical medicinemedicineHepatectomyHumansNeoplasm InvasivenessIntrahepatic CholangiocarcinomaAgedRetrospective StudiesAged 80 and overAnalysis of VarianceUnivariate analysisbusiness.industryRetrospective cohort studyGeneral MedicineMiddle AgedPrognosismedicine.diseaseSurgeryVisceraBile Ducts IntrahepaticTreatment OutcomeBile Duct Neoplasms030220 oncology & carcinogenesisFemaleSurgerybusinessInfiltration (medical)International Journal of Surgery
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“Anatomical” versus “Territorial” Belonging of the Middle Hepatic Vein: Virtual Imaging and Clinical Repercussions

2011

Background Venous drainage patterns are of vital importance in live donor liver transplantation. The purpose of this study was to delineate “anatomical-topographical” and “territorial-physiologic” patterns of the middle hepatic vein (MHV) in a 3-D liver model as determined by the Pringle line and its drainage volume of the right and left hemilivers. Methods One hundred thirty-seven consecutive live donor candidates were evaluated by 3-D CT reconstructions and virtual hepatectomies. Based on right (R) and left (L), anatomical (A) and territorial (T) belonging patterns of the MHV, each individual was assigned to one of four possible types: type I:AR–TR; type II:AL–TL; type III:AR–TL; type IV:…

AdultMaleLive donormedicine.medical_treatmentMedizinLiver transplantationHepatic VeinsDrainage volumeImaging Three-DimensionalVenous congestionmedicineLiving DonorsHepatectomyHumansVirtual imagingbusiness.industryVenous drainageAnatomyPhlebographyAnatomy RegionalMiddle AgedLiver TransplantationLiverRight hemiliverSurgeryFemaleLiving donor liver transplantationbusinessTomography X-Ray ComputedLiver Circulation
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Prediction of complexity and complications of laparoscopic liver surgery: The comparison of the Halls‐score to the IWATE‐score in 100 consecutive lap…

2020

BACKGROUND The development of laparoscopic liver surgery is slower than in other disciplines. Two different scoring systems have been proposed to estimate difficulty of laparoscopic liver resections (LLR) preoperatively. The aim of this analysis was to compare these two scores in an independent patient cohort regarding the predictability of morbidity. METHODS All LLRs performed between 01/2011 until 01/2019 were identified from our prospective institutional database. Patient characteristics as well as intra- and postoperative data were analyzed. Postoperative complications were graded according to Dindo-Clavien classification. Difficulty of LLR was classified using IWATE- and Halls-score. R…

AdultMaleLiver surgerymedicine.medical_specialtyCirrhosisOperative TimeBlood Loss SurgicalPatient characteristics030230 surgeryLiver resectionsSeverity of Illness Index03 medical and health sciencesPostoperative Complications0302 clinical medicineBlood lossPredictive Value of TestsmedicineHepatectomyHumansProspective StudiesAgedAged 80 and overHepatologybusiness.industryLiver NeoplasmsCurve analysisLength of StayMiddle Agedmedicine.diseaseConversion to Open SurgeryMagnetic Resonance ImagingSurgery030220 oncology & carcinogenesisCohortFemaleLaparoscopySurgeryTomography X-Ray ComputedbusinessHospital stayJournal of Hepato-Biliary-Pancreatic Sciences
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Translocation (X;18) in a Biphasic Synovial Sarcoma with Morphologic Features of Neural Differentiation

1998

The authors report a recurred neoplasm showing distinctive histologic, immunophenotypic, and ultrastructural features characteristic of biphasic synovial sarcoma with neural differentiation. The features include areas with a growth pattern of densely packed spindle cells in irregularly intersecting, broad fascicles, diffuse vimentin and HBA 71 immunoreactivity, expression of S-100 protein, and other neural markers. Moreover, areas with glandular structures and cellular expression of cytokeratin and epithelial membrane antigen were noted. Additionally, areas of neural-like growth pattern were positive for neuron-specific enolase, HNK-1, and protein gene product 9.5. Furthermore, cytogenetic …

AdultMaleLung NeoplasmsX ChromosomeBiphasic Synovial SarcomaEnolaseSoft Tissue NeoplasmsChromosomal translocationVimentinPolymerase Chain ReactionTranslocation GeneticImmunophenotypingPathology and Forensic MedicineGene productSarcoma SynovialCytokeratinTumor Cells CulturedmedicineHumansMolecular BiologyIn Situ Hybridization FluorescenceNeuronsmedicine.diagnostic_testbiologyChemistryCell DifferentiationPatellaCell BiologyMolecular biologyReverse transcription polymerase chain reactionKaryotypingbiology.proteinChromosomes Human Pair 18Fluorescence in situ hybridizationDiagnostic Molecular Pathology
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Interrelationships between electromyographic, mechanical, muscle structure and reflex time measurements in man.

1981

Reaction time (TRT) with its premotor (PMT) and motor time (MT) components, patellar reflex time (TRfT) with its latency (LAT) and motor time (RfMT) were studied together with isometric force production and relaxation time variables in one leg isometric knee extension. These variables were intercorrelated together with muscle biopsy variables taken from m. vastus lateralis. From these computations MT proved to demonstrate significant correlations to rate of isometric force development (RFD) (P less than 0.001), maximum force (P0) (P less than 0.001) and per cent distribution of ST fibers (P less than 0.001). It is speculated that these relationships are determined by the pattern of the moto…

AdultMaleMuscle biopsyTime Factorsmedicine.diagnostic_testPhysiologyChemistryElectromyographyMuscle RelaxationMusclesPatellar reflexAnatomyElectromyographyIsometric exerciseMuscle relaxationIsometric ContractionMotor unit recruitmentReflexReflexmedicineReaction TimeHumansmedicine.symptomMuscle contractionMuscle ContractionActa physiologica Scandinavica
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Treatment of Metachronous and Simultaneous Liver Metastases of Pancreatic Cancer

2009

<i>Aim:</i> Patients were analyzed who underwent treatment of liver metastases from pancreatic cancer. <i>Methods:</i> Selection criteria were the possibility of R0 resection of the primary and/or the liver metastases, no other sites of metastases, and the presentation of liver metastases. A comparison of treatment by surgery versus chemotherapy regarding overall survival and disease-free interval was performed. <i>Results:</i> Between 1996 and 2008, a total number of 23 patients were retrospectively identified from a prospective database of 193 cases of pancreatic cancer. In 14 cases, liver metastases were found simultaneously, and in 9 cases metachronou…

AdultMaleOncologyAntimetabolites Antineoplasticmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentMEDLINEKaplan-Meier EstimateDeoxycytidinePancreatic cancerInternal medicinemedicineHepatectomyHumansSelection (genetic algorithm)AgedRetrospective StudiesR0 resectionbusiness.industryLiver NeoplasmsRetrospective cohort studyMiddle Agedmedicine.diseaseGemcitabinePancreatic NeoplasmsFemaleSurgeryHepatectomybusinessEuropean Surgical Research
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The Objective and Subjective Caregiving Burden and Caregiving Behaviours of Parents of Adolescents with Anorexia Nervosa

2015

Objective: The study aimed to examine caregiving burden and levels of distress, accommodating behaviours, expressed emotion (EE) and carers' skills, in parents of adolescents with anorexia nervosa. Method: A semi-structured interview assessed the objective burden (time spent across caregiving tasks) in parents (n = 196) of adolescents (n = 144) receiving outpatient treatment for anorexia nervosa. Subjective burden (carers' distress), accommodating behaviours, EE and carers' skills were measured by self-report. Results: Mothers, on average, spent 2.5 h/day of care, mainly providing food and emotional support, compared with 1 h/day by fathers. The level of distress and accommodating behaviour…

AdultMaleParentsParenting/psychologyAdolescentAnorexia Nervosa/psychologycaregiving burdenMothersStressbehavioral disciplines and activitiesanorexia nervosaPsychological/psychologyCaregivers/psychologySurveys and Questionnairesmental disordersAmbulatory CareHumansParent-Child RelationsMaternal BehaviorPaternal Behavioraccommodating and enabling behaviourParentingDepressionMiddle AgedExpressed EmotionClinical PsychologyCaregiversPsychiatry and Mental Healthexpressed emotionFemalecarer skillDepression/psychologyStress PsychologicalParents/psychology
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FiberWire tension band for patellar fractures.

2015

Background Symptomatic hardware represents the most frequent complication reported following surgical treatment of patellar fracture. For this reason, some authors suggested using nonabsorbable sutures to fix the fracture with various techniques. The aim of this study was to evaluate clinical and radiological results of patients treated following a modified Pyriford technique using a FiberWire suture (Arthrex, Naples, FL, USA). Materials and methods We retrospectively evaluated a case series of  seventeen patients with displaced patellar fractures treated by open reduction and internal fixation with a modified tension band using FiberWire sutures. Clinical and radiological outcome were eval…

AdultMalePatellar fracturemedicine.medical_specialtySports medicinemedicine.medical_treatmentKnee Injuries03 medical and health sciencesFracture Fixation InternalFractures BoneYoung Adult0302 clinical medicineTension bandmedicineSettore MED/33 - Malattie Apparato LocomotoreInternal fixationHumansOrthopedics and Sports Medicine030212 general & internal medicineTension bandSurgical treatmentAgedRetrospective StudiesSutureFibrous joint030222 orthopedicsSuturesbusiness.industrySuture TechniquesPatellaMiddle Agedmedicine.diseaseSurgeryKnee fracturemedicine.anatomical_structureOrthopedic surgeryFiberWireSurgeryFemaleOriginal ArticlePatella fracturebusinessComplicationBone WiresJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
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Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

2006

We have recently described two kindreds presenting thoracic aortic aneurysm and/or aortic dissection ( TAAD) and patent ductus arteriosus (PDA)(1,2) and mapped the disease locus to 16p12.2-p13.13 (ref. 3). We now demonstrate that the disease is caused by mutations in the MYH11 gene affecting the C-terminal coiled-coil region of the smooth muscle myosin heavy chain, a specific contractile protein of smooth muscle cells (SMC). All individuals bearing the heterozygous mutations, even if asymptomatic, showed marked aortic stiffness. Examination of pathological aortas showed large areas of medial degeneration with very low SMC content. Abnormal immunological recognition of SM-MHC and the colocal…

AdultMalePathologymedicine.medical_specialty[SDV]Life Sciences [q-bio]Molecular Sequence DataANEURYSM/DISSECTION030204 cardiovascular system & hematologyBiologyThoracic aortic aneurysmProtein Structure SecondaryDISEASEFamilial thoracic aortic aneurysmCOILED-COILS03 medical and health sciencesAortic aneurysm0302 clinical medicineDuctus arteriosusGeneticsmedicineMYH11LOCUSHumans[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyAmino Acid SequenceDuctus Arteriosus Patent[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular Biology030304 developmental biologyAortic dissection0303 health sciencesAortic Aneurysm ThoracicBase SequenceMyosin Heavy ChainsSMC proteinHEAVY-CHAIN ISOFORMSAnatomymedicine.diseasePedigreeAortic Dissectionmedicine.anatomical_structureMutationbiology.proteincardiovascular systemFemaleACTA2SMOOTH-MUSCLE MYOSIN
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Parental Exposure to Polycyclic Aromatic Hydrocarbons and the Risk of Childhood Brain Tumors: The SEARCH International Childhood Brain Tumor Study

2004

Experimental evidence suggests that parental exposure to polycyclic aromatic hydrocarbons (PAH), which occurs primarily through tobacco smoke, occupational exposure, and air pollution, could increase the risk of cancer during childhood. Population-based case-control studies carried out in seven countries as part of the SEARCH Program compared data for 1,218 cases of childhood brain tumors and 2,223 controls (1976-1994). Parental occupational exposure to PAH during the 5-year period before birth was estimated with a job exposure matrix. Risk estimates were adjusted for child's age, sex, and study center. Paternal preconceptional occupational exposure to PAH was associated with increased risk…

AdultMalePediatricsmedicine.medical_specialtyAdolescentEpidemiologyJob-exposure matrixPopulationPhysiologyTobacco smokeRisk FactorsOccupational ExposureOdds RatiomedicineHumansPolycyclic Aromatic HydrocarbonsRisk factorChildeducationeducation.field_of_studyBrain Neoplasmsbusiness.industrySmokingInfant NewbornCase-control studyInfantOdds ratioPaternal ExposureCase-Control StudiesChild PreschoolPaternal ExposureFemaleRisk assessmentbusinessAmerican Journal of Epidemiology
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