Search results for "Pate"
showing 10 items of 726 documents
Jänteen pituus levossa ja isometrisen supistuksen aikana myotonometrillä mitattuna
2011
Jänne on osa lihasjänneyksikköä, joka saa aikaan vartalomme liikkeet. Jänne kiinnittyy toisesta päästään lihakseen ja toisesta päästään luuhun, ja sen tarkoitus on välittää lihak-sen supistumisesta aiheutuva voima luuhun aiheuttaen nivelen liikkumista sekä säädellä näiden liikkeiden nopeuksia. Jänne sisältää kollageeniä ja elastaania, jotka vastaavat jänteen vahvasta vetolujuudesta ja joustavuudesta. Elimistön jänteet eroavat tyypiltään, kooltaan ja muodoltaan, mutta niillä kaikilla on samankaltaisia rakenteellisia ja toimin-nallisia ominaisuuksia. Perehdyttäessä jänteen toimintaan tulee jänteen pituus saada selville. Tämän kandidaatintyön tarkoituksena oli selvittää voidaanko myotonometriä…
A minireview on NHE1 inhibitors. A rediscovered hope in oncohematology.
2015
Background: Na+/H+ exchanger-1 (NHE-1) is involved in pH regulation and is up-regulated in different malignancies. Activation of NHE-1 is one way for allowing cells to avoid intracellular acidification and protect them against apoptosis. Inhibitors of NHE-1 are able to decrease intracellular pH and induce apoptosis. Some statins can also act by partial inhibition of NHE-1. This review presents progress in understanding the mechanisms of action of these inhibitors, connections with certain genetic mutations and acquired treatment resistance, as well as new patents on them. Methods: A MEDLINE search for original and review articles using key terms, Na+/H+ exchanger, leukemia, cariporide, and …
IPR-aineistojen mahdollisuuksia, replikointitarpeita ja teknisiä haasteita
2021
Tässä artikkelissa tehdään katsaus aineettomien oikeuksien eli IPR- (intellectual property rights) aineistoihin erityisesti suomalaisesta ja eurooppalaisesta näkökulmasta. Keskityn patentti-, hyödyllisyysmalli-, tavaramerkki- ja mallioikeusaineistoihin eli teollisoikeuksiin jättäen tekijänoikeudet tarkastelun ulkopuolelle. Digitalisaation myötä rekisteriaineistojen laatu ja saatavuus ovat jatkuvasti lisääntyneet ja IPR-järjestelmien toiminnan tutkimus sekä hypoteesien empiirinen testaus ovat tulleet mahdolliseksi ennennäkemättömällä tavalla. Eräitä mielenkiintoisia aiheita, joiden tutkimuksen yhä laadukkaammat IPR-aineistot mahdollistavat ovat 1) kokonaisvaltaisempi IPR-analyysi, joka paten…
Tra madre e padre. Immagini di educazione familiare nel cinema degli anni Cinquanta
2017
Questo contributo propone un’analisi delle relazioni genitoriali poste in essere nelle famiglie italiane degli anni Cinquanta. Seguendo le suggestioni della recente Visual History, viene scelto il cinema come fonte cui attingere per ricostruire i rapporti tra madre e padre che, nel “decennio più lungo del secolo breve”, si avviavano ad una lenta ridefinizione. Il codice paterno, che il cinema neorealista descrive in tutta la sua problematicità, e il codice materno, che il melò consegna al pubblico nella sua ambiguità, sono descritti come due mondi separati che solo nel genere della commedia sembrano inaugurare una loro ricomposizione, se pur difficoltosa e solo abbozzata. Il modello offerto…
The role of parental effect and relatedness on early development of vendace and whitefish in short and long winter
2015
Tutkimuksessa testattiin ilmastonmuutoksen vaikutuksia muikun (Coregonus albula) ja siian (C. lavaretus) alkioiden kuolevuuteen, alkioiden kasvuun, kuoriutumisaikaan ja kuoriutumiskokoon. Koejärjestely toteutettiin sekä muikulla että siialla yksilöllisinä ristiinhedelmöityksinä tavoitteena selvittää naaraan ja koiraan vaikutusta sekä niiden yhdysvaikutusta mitattaviin muuttujiin. Sen lisäksi muikun emokalojen sukulaisuutta tutkittiin mikrosatelliittien avulla, jotta nähtäisiin voiko sisäsiitosdepressio selittää eroja jälkeläisten kuolevuudessa eri emoparien välillä. Munia haudottiin lyhyen talven sekä pitkän talven lämpöoloissa. Siian alkioiden kuolleisuus oli huomattavasti alhaisempaa kuin…
Biopiracy in India: Seed diversity and the scramble for knowledge.
2018
Abstract Background: Biopiracy has usually been discussed mostly in the context of the life sciences, sometimes in dialogue with legal debates or political implications. This paper provides a humanities perspective on contemporary discussions of biopiracy and biopatenting. Hypothesis It proceeds from the hypothesis that contemporary debates and practices of biopiracy can be understood as harking back to colonial legacies, which systematically disregard “native” knowledge or seek to appropriate it for their own purposes. Results Drawing on the work of Vandana Shiva, the present article seeks to redefine the notion of ownership of knowledge from a cultural studies perspective. Exploring the 2…
Fathers’ narratives on support and agency : a case study of fathers in a Finnish child welfare NGO
2017
In Finland, one of the Nordic countries, shared parenting is widely supported through, e.g. family policies and legislation. This is also evident in daily parental practices, as fathers’ share in childcare has increased notably since the late 1980s. Unfortunately, this is not the whole picture of Finnish and Nordic fatherhood: practitioners in child welfare also encounter many fathers with various problems in parenting and life management. In this article, we examine the narratives of fathers who have sought and received support from a Finnish nationwide child welfare NGO. Our research question is: What types of narratives on seeking and receiving support and on their agency do fathers prod…
Considering Genetics in Tendinopathy Management
2018
Laparoscopic treatment of a large pedunculated hemangioma of the liver: a case report
2016
Hepatic hemangiomas are the most common benign tumors of the liver, often asymptomatic and discovered incidentally. A 62-year-old woman was referred to our Institution under the suspicion of having an 8 cm-sized GIST. Due to the atypical features of the lesion on TC scan, a biopsy was performed. We report the case of pedunculated hepatic hemangioma with the aim to discuss the diagnostic approach, the possible causes of misdiagnosis and the opportunity of the laparoscopic approach.
Is cell salvage safe in liver resection? A pilot study
2007
Abstract Study Objective To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). Design Observational study. Setting Operating room in a university hospital. Measurements 6 patients undergoing hemihepatectomy or aortobifemoral bypass with intraoperative blood loss of more than 800 mL. Samples were drawn from the central venous catheter, from the reservoir of a CS recovery system, and from the processed blood in each patient to determine interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor (TNF), complement C3a, and the terminal complement complex C5b-9. Microbiological ana…