Search results for "Patella"

showing 10 items of 80 documents

Methotrexate-Loaded Polymethylmethacrylate Bone Cement for Local Bone Metastasis Therapy: Pilot Animal Study in the Rabbit Patellar Groove

2008

Local chemotherapy is an option in bone metastasis treatment. On the other hand, evaluation of side effects on bone is a difficult issue in drug development and biomaterials research. Most animal models to date are inappropriate or not feasible. Rabbits are an alternative to other bigger mammals and have an appropriate bone structure compared to rats and mice. The patellar groove model of the rabbit offers a standardized and sensitive model to evaluate bone-compromising drug effects. We tested the system with a reproducible polymethacrylate implant as carrier and loaded this system with methotrexate. Three methotrexate concentrations were used in the test samples (250 mg, 1 g and 4 g per 40…

medicine.medical_specialtymedicine.medical_treatmentBone NeoplasmsPilot ProjectsMetastasisDrug DiscoverymedicineAnimalsPolymethyl MethacrylatePharmacology (medical)PharmacologyChemotherapybusiness.industryBone CementsBone metastasisPatellaProstheses and ImplantsGeneral Medicinemedicine.diseaseBone cementSurgeryPre-clinical developmentDisease Models AnimalMethotrexateInfectious DiseasesOncologyPatellaMethotrexateRabbitsImplantbusinessmedicine.drugChemotherapy
researchProduct

Hoffa’s fat pad thickness: a measurement method with sagittal MRI sequences

2021

Abstract Background Hoffa’s fat pad is a structure located within the fibrous joint capsule of the knee joint, but outside the synovial cavity. It plays an important biomechanical and metabolic role in knee joint, reducing the impact of forces generated by loading and producing cytokines. Changes in its size can induce modifications in the knee homeostasis. However, a great variability exists regarding its measurements. This work aims to evaluate the reliability of a measurement method of Hoffa’s fat pad dimensions through MRI. Methods 3T sagittal IW 2D TSE fat-suppressed MRI sequences, taken from the OAI (Osteoarthritis initiative) database, of 191 male and female patients, aged between 40…

musculoskeletal diseasesAdultMaleKnee JointOsteoarthritisKnee JointHoffa’s fat padFat pad030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesNeuroradiologyAged030203 arthritis & rheumatologyAged 80 and overMeasurement methodInfrapatellar fat padbusiness.industryHofa’s fat pad · Infrapatellar fat pad · Knee joint · OAI · MRIUltrasoundReproducibility of ResultsGeneral MedicineOAIMiddle AgedOsteoarthritis Kneemedicine.diseaseMagnetic Resonance ImagingSagittal planemedicine.anatomical_structureAdipose TissueMusculoskeletal RadiologyInfrapatellar fat padFemalebusinessNuclear medicineMRIFollow-Up Studies
researchProduct

Lower Limb Dominance, Morphology, and Sonographic Abnormalities of the Patellar Tendon in Elite Basketball Players: A Cross-Sectional Study.

2019

Context Patellar tendinopathy is common in basketball players, and structural ultrasound abnormalities can be found in symptomatic and asymptomatic tendons. Lower limb dominance may also be a critical load factor, potentially leading to overloading of the patellar tendon. Objective To describe and compare the prevalence by lower limb dominance of patellar tendons with structural and vascular abnormalities and to describe the morphologic measures of tendons without abnormalities among adult male elite basketball players. Design Cross-sectional study. Setting Medical center of a professional basketball team in the Spanish league. Patients or Other Participants A total of 73 adult male elite …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyBasketballCross-sectional studyPhysical Therapy Sports Therapy and RehabilitationBasketballAsymptomaticLower limbFunctional Laterality030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationPatellar LigamentmedicineHumansOrthopedics and Sports MedicineKneeDominance (genetics)UltrasonographyLegbusiness.industryUltrasound030229 sport sciencesGeneral MedicinePatellamusculoskeletal systemPatellar tendonSpainTendinopathyPatellar tendinopathymedicine.symptombusinessJournal of athletic training
researchProduct

Effect of patella resurfacing on functional outcome and revision rate in primary total knee arthroplasty (Review).

2021

Anterior knee pain, as well as patellofemoral disorders, after total knee arthroplasty are important reasons for revision in total knee arthroplasty. Current prosthesis designs include patellar components for patella replacement, and together with improved rational design of the prosthesis and advancement in knee alignment these appear to reduce the incidence of anterior knee pain following total knee replacement, even if the etiology of anterior knee pain remains unclear. However, new complications related to patella resurfacing emerge with this approach. At present, there are three strategies involving patella replacement in total knee arthroplasty: There are surgeons who always replace t…

musculoskeletal diseasesCancer Researchmedicine.medical_specialtybusiness.industryTotal knee arthroplastyGeneral MedicineReviewmusculoskeletal systemSurgeryImmunology and Microbiology (miscellaneous)medicineRevision ratePatellabusinesshuman activitiesExperimental and therapeutic medicine
researchProduct

Stellenwert der MR-Tomographie bei traumatischen Patellaluxationen

1995

PURPOSE To describe the MR imaging findings in patients with lateral patellar dislocation. MATERIAL AND METHODS The MRIs of 31 patients with patellar dislocation were evaluated retrospectively. Arthroscopic surgery was performed in 23 cases. RESULTS Hemarthrosis was found in 30/31, contusions of the lateral femoral condyle in 30/31 and of the medial patellar facet in 26/31 cases. Injury of the medial patellar retinaculum was seen in 28/31 cases. Osteochondral fractures were found in 18 patients; compared to arthroscopy there were one false-positive and 5 false-negative findings concerning loose cartilage bodies. In 7 cases, patellar dislocation was not suspected before MR imaging. CONCLUSIO…

musculoskeletal diseasesFacet (geometry)medicine.diagnostic_testbusiness.industryCartilageArthroscopyAnatomyHemarthrosismusculoskeletal systemmedicine.diseaseMr imagingmedicine.anatomical_structureLateral femoral condyleMedicineRadiology Nuclear Medicine and imagingIn patientPatellabusinessNuclear medicineRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
researchProduct

Le Fratture di Rotula

2015

Patellar fractures are relatively uncommon, accounting for approximately 1% of all fractures. Non-operative treatment represents the best choice for undisplaced patellar fractures. However, surgery becomes necessary when fractures are displaced by more than 2 mm, and may include open reduction and internal fixation. Accurate reduction and rigid fixation are required in order to allow early knee mobilization and to obtain a better clinical outcome. Several techniques have been described for patellar fracture fixation, such as tension band wiring, interfragmentary screw fixation, and the combination of screw fixation and cerclage. In this article up-to-date diagnosis, classification and treat…

musculoskeletal diseasesFibrous jointmedicine.medical_specialtybusiness.industryTension band wiringmedicine.medical_treatmentfiberwirefratture di rotula fratture di ginocchio trauma rotulamusculoskeletal systemmedicine.diseaseSurgeryScrew fixationFixation (surgical)medicine.anatomical_structurefrattureOrthopedic surgerySettore MED/33 - Malattie Apparato LocomotoreMedicineInternal fixationPatella fracturebusiness
researchProduct

The influence of lateral release on patello-femoral joint loading in knee arthroplasty

1992

Eight fresh, cadaveric knees have been fitted with four different total knee cemented prostheses. Loading forces at the bone implant fixation interface of the patella component have been measured in a knee joint testing rig by four miniaturized force transducers, before and after a lateral release of the patellar retinaculum. The lateral release resulted in a significant local force reduction in the lateral and/or proximal quadrant of the patella resection plane depending on the knee flexion angle, quadriceps tensile force direction, and the patellar prosthesis design.

musculoskeletal diseasesKnee Jointmedicine.medical_treatmentTransducersIn Vitro TechniquesKnee JointProsthesis DesignProsthesisWeight-BearingCadaverHumansMedicineOrthopedics and Sports MedicineFixation (histology)OrthodonticsLateral releasebusiness.industryPatellamusculoskeletal systemArthroplastyLigaments ArticularSurgeryPatellaKnee ProsthesisbusinessCadaveric spasmhuman activitiesInternational Orthopaedics
researchProduct

A Locked Intraosseous Nail for Transverse Patellar Fractures: A Biomechanical Comparison with Tension Band Wiring Through Cannulated Screws.

2018

Background Displaced transverse patellar fractures require open reduction and internal fixation. State-of-the-art stabilization techniques are tension band wiring (TBW) using Kirschner wires or cannulated screws. These techniques are associated with high rates of secondary fracture displacement, implant migration, implant prominence, wound-healing disturbances, and the need for implant removal. Recently, a locked intraosseous patellar nail prototype was developed. The aim of the present study was to investigate the biomechanical performance of this nail compared with TBW using cannulated screws. Methods Seven paired fresh-frozen human cadaveric knees were stripped of all soft tissues except…

musculoskeletal diseasesMalemedicine.medical_treatmentBone ScrewsKnee InjuriesBone NailsOsteotomy03 medical and health sciencesFracture Fixation InternalFractures Bone0302 clinical medicineCadaverFracture fixationmedicineCadaverInternal fixationHumansOrthopedics and Sports MedicineRange of Motion ArticularOrthodontics030222 orthopedicsbusiness.industryTension band wiring030208 emergency & critical care medicineGeneral MedicinePatellamusculoskeletal systemmedicine.diseaseBiomechanical Phenomenamedicine.anatomical_structureSurgeryFemaleQuadriceps tendonPatella fractureCadaveric spasmbusinessThe Journal of bone and joint surgery. American volume
researchProduct

MRI evaluation to predict tendon size for knee ligament reconstruction.

2017

Background The aim of this study is to evaluate a possible correlation between specific anthropometric parameters and sizes of knee tendons commonly used for ACL reconstruction. We hypothesized that specific clinical and radiological knee measurements could be better tendon sizes predictors than age, gender, height and weight. Materials and methods 100 consecutive patients were enrolled and 77 patients met the inclusion criteria of the study. All patients underwent a MRI of the knee with a 1.5 T super conducting MR System. For each patient, anthropometric data such as gender, height, weight, body mass index (BMI) and knee circumference were recorded. Specific MRI knee measurements were perf…

musculoskeletal diseasesOrthodontics030222 orthopedicsbusiness.industry05 social sciences050801 communication & media studiesmusculoskeletal systemCircumferenceTendon03 medical and health sciences0508 media and communications0302 clinical medicinemedicine.anatomical_structureGracilis tendonKnee ligamentquadriceps tendon autograft patellar tendon autograft acl reconstruction mri graft size measurement preoperative measures hamstringmedicineOrthopedics and Sports MedicinePatellaOriginal ArticleQuadriceps tendonbusinessBody mass indexHamstringMuscles, ligaments and tendons journal
researchProduct

2019

Ultrasound tissue characterization (UTC) imaging has been previously used to describe the characteristics of patellar and Achilles tendons. UTC imaging compares and correlates successive ultrasonographic transverse tendon images to calculate the distribution of four color-coded echo-types that represent different tendon tissue types. However, UTC has not been used to describe the characteristics of patellar tendons after anterior cruciate ligament reconstruction (ACLR). The aim of this cross-sectional study was to assess the intra and inter-rater reliability of the UTC in unharvested and harvested patellar tendons of patients undergoing ACLR. Intra and inter-rater reliability of both UTC da…

musculoskeletal diseasesOrthodonticsmedicine.medical_specialtyAnterior cruciate ligament reconstructionbusiness.industrymedicine.medical_treatmentAnterior cruciate ligamentRehabilitationUltrasoundPhysical Therapy Sports Therapy and Rehabilitation030229 sport sciencesTissue characterizationmusculoskeletal systemTendon03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureOrthopedic surgerymedicineOrthopedics and Sports MedicinePatella030212 general & internal medicinebusinessReliability (statistics)BMC Sports Science, Medicine and Rehabilitation
researchProduct