Search results for "Pathology"

B and T lymphocytes are affected in lysosomal disorders--an immunoelectron microscopic study.

1991

Circulating lymphocytes of four patients with mucopolysaccharidoses II and IIIA, four patients with juvenile neuronal ceroid-lipofuscinosis, one patient each with glycogenosis type II, infantile neuronal ceroid-lipofuscinosis, and Gaucher disease were classified by immunoelectron microscopy as B or T lymphocytes. Disease-specific lysosomal inclusions as well as non-specific lysosomal organelles, especially Gall bodies were identified in B and T lymphocytes. These non-quantitative studies indicate that both B and T lymphocytes participate in the lysosomal storage process.

Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs

2017

Background Mismatch repair proteins (MMRPs) are a group of nuclear enzymes that participate in the repair of base mismatches that occur during DNA replication in all proliferating cells. The most studied MMRPs are hMSH2 and hMLH1, which are known to be highly expressed in normal tissues. A loss of MMRPs leads to the accumulation of DNA replication errors in proliferating cells. Ki-67 is a biomarker regarded to be the gold-standard tool for determining cell proliferation by immunohistochemical methods. The aim of this study was to investigate the immunohistochemical expression of hMLH1, hMSH2 and Ki-67 proteins in ameloblastomas and tooth germs, to contribute to the understanding of the deve…

Anticipatory postural adjustments during joint action coordination

2019

International audience; There is a current claim that humans are able to effortlessly detect others’ hidden mental state by simply observing their movements and transforming the visual input into motor knowledge to predict behaviour. Using a classical paradigm quantifying motor predictions, we tested the role of vision feedback during a reach and load-lifting task performed either alone or with the help of a partner. Wrist flexor and extensor muscle activities were recorded on the supporting hand. Early muscle changes preventing limb instabilities when participants performed the task by themselves revealed the contribution of the visual input in postural anticipation. When the partner perfo…

Isolated coronary anomalies and sudden death in the young

2011

Environment and Endometriosis: A toxic relationship

2015

Endometriosis is a common, be- nign, estrogen-dependent gynecological dis- ease that represents one of the main causes of hospitalization in industrialized countries. It is well established that a large amount of natural and man-made chemicals are present in the en- vironment and both humans and animals are exposed to them. Dioxin and dioxin-like com- pounds have long biological half-life, can accu- mulate within the organism and could negative- ly affect several physiological processes. The purpose of this review is to provide an overview of the possible relationship between these chemicals and the pathogenesis of en- dometriosis.

Cavidad de Stafne: Estudio retrospectivo de 11 casos

2006

Podeu consultar la versió en anglès a: http://hdl.handle.net/2445/48487

Orthorexic tendencies and healthy eating in university students: which association with eating disorders, psychopathology, and defense mechanisms?

2021

Orthorexic tendencies and healthy eating in university students: which association with eating disorders, psychopathology, and defense mechanisms? higher in some immature defenses (passive aggression and somatization) than healthy-eating individuals, while no differences were found in mature and neurotic defense styles. Conclusions. These results support the existence of significant differences between ON and other (non-problematic) healthy eating behaviors.

Postoperative Sagittal Balance Has Only a Limited Role in the Development of Adjacent Segment Disease After Lumbar Spine Fusion for Degenerative Lumb…

2022

Study Design. Retrospective additional analysis of a prospective follow-up study. Objectives. We aimed to find out whether poor postoperative sagittal alignment increases revisions for adjacent segment disease (ASD) after lumbar spine fusion (LSF) performed for degenerative lumbar spine disease. Summary of Background Data. Revisions for ASD accumulate over time after LSF for degenerative lumbar spine disease. The etiology of ASD is considered multifactorial. Yet, the role of postoperative sagittal balance in this process remains controversial. Materials and Methods. A total of 215 consecutive patients who had undergone an elective LSF surgery for spinal stenosis with (80%) or without (20%) …

Chikungunya, a water-borne disease: how have the inhabitants of the Island of Reunion handled the crisis ?

2012

The Reunion Island faced a great epidemic of chikungunya in 2005-2006. Chikungunya is a vector-borne disease transmitted by a mosquito. It is in the town of St Pierre, in the south of the island, that the first cases of chikungunya appeared in 2005. We chose to work on one area of the Ravine des Cabris, in the town of Saint-Pierre in the south of the Reunion Island, where individual housing outweighs the block of flats, where houses are surrounded by gardens – closed in for most of them, well watered- and where the foliage is important: we are in a green urban area which is a place of high prevalence. It concentrates the conditions that favour the contact man / vector and therefore the spre…

Sweat Gland Biopsy: A Possible Early Diagnostic Tool in the Anderson-Fabry Disease

2016

Anderson-Fabry disease is a rare X-linked lysosomal storage disorder caused by deficient or absent activity of the enzyme alfa-galactosidase A. This defect enzyme leads to accumulation of glycolipids, primarily globotriaosylceramide (Gb3), in the vascular endothelium of several organs, including the skin, kidneys, nervous system, and heart. The characteristic early clinical features of Fabry disease include acroparaesthesia, angiokeratoma, heat intolerance, hypohidrosis, cornea verticillata and gastrointestinal symptoms. Later complications occur with the disease progression and include progressive renal failure, hypertrofic cardiomyopathy, cerebrovascular disease and reduced life expectanc…