Search results for "Peace"

‘Less Stale, Only Slightly Less Male, but Overwhelmingly Less Pale’: the 2015 New Conservative Brexiters in the House of Commons

2019

AbstractThis article will study the new face of Conservative Euroscepticism in the House of Commons, with a special focus on the 2015 intake of MPs who were supposedly ‘less stale, male and pale’ and their attitudes to the British referendum on the EU. In this respect, this article will also take a specific interest in new Conservative Black and Asian Minority Ethnic (BAME) MPs who turned out to be more active on the ‘leave’ side of the referendum campaign, thus serving as a showcase for the party's strategy of ‘decontaminating’ the Brexit brand and its hyperglobalist geopolitical perspective.

How women are imagined through conceptual metaphors in United Nations Security Council Resolutions on women, peace and security

2017

United Nations Security Council Resolution 1325 is a landmark pronouncement on the Women, Peace and Security Agenda. Not only does this resolution highlight the important role of the involvement of women in peace processes, but it also stresses the importance of their equal participation in all efforts for the maintenance and promotion of peace. Furthermore, it also triggers the approval of some other resolutions, which are all further elaborations on that first document. The aim of this paper is to analyse, from a cognitive linguistic perspective, the way in which women are actually narrated in these pronouncements by means of the two conceptual metaphors that are most often repeated: WOME…

Terrorism communication : characteristics and emerging perspectives in the scientific literature 2002–2011

2013

This paper aims to clarify current knowledge on the contribution of communication to crisis management in the case of terrorism incidents. This is done by means of a systematic review of the scientific literature on terrorism communication over the last 10 years to identify the many challenges facing communication in such crises, and represents the first attempt of its kind. To date, within the literature on terrorism communication, much attention has been paid to chemical, biological, radiological or nuclear hazards. Terrorism crises are complex and challenging. Preparedness for such diverse low-probability high-impact crises can best be included in a wider educative approach. Terrorism cr…

Pourquoi l’urologue doit s’intéresser à l’immunothérapie, quelles sont les indications établies en 2018 et celles en perspectives ?

2018

Resume L’immunotherapie est un concept ancien en oncologie, qui consiste a exploiter l’immunite innee antitumorale comme traitement anti-cancereux. Tandis que les premieres immunotherapies consistaient a stimuler globalement le systeme immunitaire (interleukine, interferon), l’immunotherapie « moderne » consiste a bloquer les mecanismes par lesquels les cellules cancereuses parviennent a echapper a l’immunite antitumorale, pour que les cellules du systeme immunitaire puissent les detecter et les eliminer. Deux voies permettant a la cellule tumorale d’echapper au systeme immunitaire ont ete identifiees : la voie de PD1 et CTLA4 qui sont les cibles des principales molecules faisant l’actualit…

Long-term physical activity modulates brain processing of somatosensory stimuli: Evidence from young male twins.

2016

Leisure-time physical activity is a key contributor to physical and mental health. Yet the role of physical activity in modulating cortical function is poorly known. We investigated whether precognitive sensory brain functions are associated with the level of physical activity. Physical activity history (3-yr-LTMET), physiological measures and somatosensory mismatch response (sMMR) in EEG were recorded in 32 young healthy twins. In all participants, 3-yr-LTMET correlated negatively with body fat%, r = −0.77 and positively with VO2max, r = 0.82. The fat% and VO2max differed between 15 physically active and 17 inactive participants. Trend toward larger sMMR was seen in inactive compared to ac…

Genetic association study of childhood aggression across raters, instruments, and age

2021

AbstractChildhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. We analyzed phenotype assessments for a total of 328 935 observations from 87 485 children aged between 1.5 and 18 years, while accounting for sample overlap. We also meta-analyzed within subsets of the data, i.e., within rater, instrument and age. SNP-heritability for the overall meta-analysis (AGGoverall) was 3.31% (SE = 0.0038). We found no genome-wide significant SNPs for AGGoverall. The gene-based analysis returned three sign…

International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods

2018

International audience; Increasing numbers of laboratories develop new methods based on gas-liquid and high-performance liquid chromatography to determine serum concentrations of oxygenated cholesterol metabolites such as 7alpha-, 24(S)-, and 27-hydroxycholesterol. We initiated a first international descriptive oxycholesterol (OCS) survey in 2013 and a second interventional survey 2014 in order to compare levels of OCS reported by different laboratories and to define possible sources of analytical errors. In 2013 a set of two lyophilized serum pools (A and B) was sent to nine laboratories in different countries for OCS measurement utilizing their own standard stock solutions. In 2014 eleven…

Long-term Immune Response to Hepatitis B Virus Vaccination Regimens in Adults With Human Immunodeficiency Virus 1: Secondary Analysis of a Randomized…

2016

International audience; IMPORTANCE:Data on long-term immune responses to hepatitis B virus (HBV) vaccination in adults with human immunodeficiency virus 1 (HIV-1) infection are scarce.OBJECTIVE:To compare long-term (up to month 42) immune responses to the standard HBV vaccination regimen with a 4-injection intramuscular double-dose regimen and a 4-injection intradermal low-dose regimen.DESIGN, SETTING, AND PARTICIPANTS:The phase 3, open-label, multicenter parallel-group (1:1:1 allocation ratio) randomized clinical trial was conducted from June 28, 2007, to October 23, 2008, at 33 centers in France. Participants included 437 HBV-seronegative adults with HIV-1 and CD4 cell counts of more than…

Quantum field inspired model of decision making: Asymptotic stabilization of belief state via interaction with surrounding mental environment

2018

This paper is devoted to justification of quantum-like models of the process of decision making based on the theory of open quantum systems, i.e. decision making is considered as decoherence. This process is modeled as interaction of a decision maker, Alice, with a mental (information) environment ${\cal R}$ surrounding her. Such an interaction generates "dissipation of uncertainty" from Alice's belief-state $\rho(t)$ into ${\cal R}$ and asymptotic stabilization of $\rho(t)$ to a steady belief-state. The latter is treated as the decision state. Mathematically the problem under study is about finding constraints on ${\cal R}$ guaranteeing such stabilization. We found a partial solution of th…

2018

Haplotypes of the Gabra2 gene encoding the α2-subunit of the GABAA receptor (GABAAR) are associated with drug abuse, suggesting that α2-GABAARs may play an important role in the circuitry underlying drug misuse. The genetic association of Gabra2 haplotypes with cocaine addiction appears to be evident primarily in individuals who had experienced childhood trauma. Given this association of childhood trauma, cocaine abuse and the Gabra2 haplotypes, we have explored in a mouse model of early life adversity (ELA) whether such events influence the behavioral effects of cocaine and if, as suggested by the human studies, α2-GABAARs in the nucleus accumbens (NAc) are involved in these perturbed beha…