Search results for "Perl"
showing 10 items of 383 documents
Analysis and simulation of creativity learning by means of artificial neural networks
2007
The paper presents a new neural network approach for analysis and simulation of creative behavior. The used concept of Dynamically Controlled Neural Gas (DyCoNG) entails a combination of Dynamically Controlled Network [Perl, J. (2004a). A neural network approach to movement pattern analysis. Human Movement Science,23, 605-620] and Growing Neural Gas (Fritzke, 1995) by quality neurons. A quality neuron reflects the rareness of a piece of information and therefore can measure the originality of a recorded activity that was assigned to the neuron during the network training. The DyCoNG approach was validated using data from a longitudinal field-based study. The creative behavior of 42 particip…
Void superlattice formation in electron irradiated CaF2: Theoretical analysis
2010
Abstract CaF2 is widely adopted as deep-UV window material and thin film optical coating. The void superlattice was observed experimentally under electron irradiation at room temperature. We performed kinetic Monte Carlo (kMC) simulations of the initial stages of the process when short- and intermediate-range order of defects in small Ca colloids and larger interstitial aggregates (F2 gas voids) is created. The kMC model includes fluorine interstitial–vacancy pair creation, defect diffusion, similar defect attraction and dissimilar defect recombination. Special attention is paid to the statistical analysis of the defect aggregate distribution functions under different conditions (dose rate,…
Void lattice formation in electron irradiated CaF 2 : Statistical analysis of experimental data and cellular automata simulations
2016
Abstract Calcium fluoride (CaF2) is an important optical material widely used in both microlithography and deep UV windows. It is known that under certain conditions electron beam irradiation can create therein a superlattice consisting of vacancy clusters (called a void lattice). The goal of this paper is twofold. Firstly, to perform a quantitative analysis of experimental TEM images demonstrating void lattice formation, we developed two distinct image filters. As a result, we can easily calculate vacancy concentration, vacancy cluster distribution function as well as average distances between defect clusters. The results for two suggested filters are similar and demonstrate that experimen…
Radiation-hard semiconductor detectors for SuperLHC
2005
An option of increasing the luminosity of the Large Hadron Collider (LHC) at CERN to 10^35 cm^(- 2) s(- 1) has been envisaged to extend the physics reach of the machine. An efficient tracking down to a few centimetres from the interaction point will be required to exploit the physics potential of the upgraded LHC. As a consequence, the semiconductor detectors close to the interaction region will receive severe doses of fast hadron irradiation and the inner tracker detectors will need to survive fast hadron fluences of up to above 1016 cm 2. The CERN-RD50 project ''Development of Radiation Hard Semiconductor Devices for Very High Luminosity Colliders'' has been established in 2002 to explore…
Entanglement control via reservoir engineering in ultracold atomic gases
2013
We study the entanglement of two impurity qubits immersed in a Bose-Einstein condensate (BEC) reservoir. This open quantum system is particularly interesting because the reservoir and system parameters are easily controllable and the reduced dynamics is highly non-Markovian. We show how the model allows for interpolation between a common dephasing scenario and an independent dephasing scenario by simply modifying the wavelength of the superlattice superposed to the BEC, and how this influences the dynamical properties of the impurities. We demonstrate the existence of very rich entanglement dynamics correspondent to different values of reservoir parameters, including phenomena such as entan…
Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and …
2016
WOS: 000393031600001
Wikipedia network analysis of cancer interactions and world influence
2019
AbstractWe apply the Google matrix algorithms for analysis of interactions and influence of 37 cancer types, 203 cancer drugs and 195 world countries using the network of 5 416 537 English Wikipedia articles with all their directed hyperlinks. The PageRank algorithm provides the importance order of cancers which has 60% and 70% overlaps with the top 10 cancers extracted from World Health Organization GLOBOCAN 2018 and Global Burden of Diseases Study 2017, respectively. The recently developed reduced Google matrix algorithm gives networks of interactions between cancers, drugs and countries taking into account all direct and indirect links between these selected 435 entities. These reduced n…
Perlecan is critical for heart stability
2008
Aims Perlecan is a heparansulfate proteoglycan found in basement membranes, cartilage, and several mesenchymal tissues that form during development, tumour growth, and tissue repair. Loss-of-function mutations in the perlecan gene in mice are associated with embryonic lethality caused primarily by cardiac abnormalities probably due to hemopericards. The aim of the present study was to investigate the mechanism underlying the early embryonic lethality and the pathophysiological relevance of perlecan for heart function. Methods and results Perlecan-deficient murine embryonic stem cells were used to investigate the myofibrillar network and the electrophysiological properties of single cardiomy…
Familial hypercholesterolaemia: A global call to arms
2015
Familial Hypercholesterolaemia (FH) is the commonest autosomal co-dominantly inherited condition affecting man. It is caused by mutation in one of three genes, encoding the low-density lipoprotein (LDL) receptor, or the gene for apolipoprotein B (which is the major protein component of the LDL particle), or in the gene coding for PCSK9 (which is involved in the degradation of the LDL-receptor during its cellular recycling). These mutations result in impaired LDL metabolism, leading to life-long elevations in LDL-cholesterol (LDL-C) and development of premature atherosclerotic cardiovascular disease (ASCVD) [1], [2] and [3]. If left untreated, the relative risk of premature coronary artery d…
A proposal to redefine familial combined hyperlipidaemia -- third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the scientific sess…
2002
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