Search results for "Perspective"
showing 10 items of 1523 documents
State of the Art on Sustainability Assessment of Positive Energy Districts: Methodologies, Indicators and Future Perspectives
2021
The concept of Positive Energy District is one of the main areas of research and extensive applications of the principles of the clean energy transition within the building sector. In the past years, the most widely accepted definitions have focused specifically on carbon neutrality, while several other aspects regarding all sustainability approaches (including environmental, social and economic perspective) were included qualitatively or to a lesser degree. This paper proposes a discussion on the state of the art of the sustainability assessment of Positive Energy Districts, by investigating environmental, social and economic sustainability applications. The three sustainability dimensions…
Electrocardiographic Imaging for Atrial Fibrillation: A Perspective From Computer Models and Animal Experiments to Clinical Value
2021
[EN] Electrocardiographic imaging (ECGI) is a technique to reconstruct non-invasively the electrical activity on the heart surface from body-surface potential recordings and geometric information of the torso and the heart. ECGI has shown scientific and clinical value when used to characterize and treat both atrial and ventricular arrhythmias. Regarding atrial fibrillation (AF), the characterization of the electrical propagation and the underlying substrate favoring AF is inherently more challenging than for ventricular arrhythmias, due to the progressive and heterogeneous nature of the disease and its manifestation, the small volume and wall thickness of the atria, and the relatively large…
The emergence of Vibrio pathogens in Europe : ecology, evolution, and pathogenesis (Paris, 11-12th March 2015)
2015
Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring during episodes of unusually warm weather. Similar patterns were also observed in Vibrio-associated diseases affecting marine organisms such as fish, bivalves and corals. Basic knowledge is still lacking on the ecology and evolutionary biology of these bacteria as well as on their virulence mechanisms. Current limitations in experimental systems to study infection and the lack of diagnostic tools still prevent a better understanding of Vibrio…
Estimating the age and season-at-death of ungulates from the analysis of archaeological dental cementum: Recent improvements and perspectives from th…
2018
International audience
Chronologie des faciès mobiliers du Cambrésis de La Tène moyenne au début de l’époque romaine.
2016
International audience
A Focus on the Cerebellum: From Embryogenesis to an Age-Related Clinical Perspective
2021
The cerebellum and its functional multiplicity and heterogeneity have been objects of curiosity and interest since ancient times, giving rise to the urge to reveal its complexity. Since the first hypothesis of cerebellar mere role in motor tuning and coordination, much more has been continuously discovered about the cerebellum’s circuitry and functioning throughout centuries, leading to the currently accepted knowledge of its prominent involvement in cognitive, social, and behavioral areas. Particularly in childhood, the cerebellum may subserve several age-dependent functions, which might be compromised in several Central Nervous System pathologies. Overall, cerebellar damage may produce nu…
Revisiting the happy-productive worker thesis from a eudaimonic perspective: a systematic review
2021
The happy-productive worker thesis (HPWT) is considered the Holy Grail of management research, and it proposes caeteris paribus, happy workers show higher performance than their unhappy counterparts. However, eudaimonic well-being in the relationship between happiness and performance has been understudied. This paper provides a systematized review of empirical evidence in order to make a theoretical contribution to the happy-productive worker thesis from a eudaimonic perspective. Our review covers 105 quantitative studies and 188 relationships between eudaimonic well-being and performance. Results reveal that analyzing the eudaimonic facet of well-being provides general support for the HPWT…
Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy
2019
The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins. Genetic proteinopathies may occur either in the presence of a normal chaperoning system, which is unable to assist the defective myelin protein in its folding and migration, or due to mutations in chaperone genes, leading to functional defects in assisting myelin maturation/migration. The latter are a subgroup of genetic chaperonopathies causing demyelination. In this brief review, we describe some paradigmatic examples pertaining to the chaperonins Hsp60 (HSPD1,…