Search results for "Perspective"

showing 10 items of 1523 documents

Sortase A Inhibitors: Recent Advances and Future Perspectives

2015

Here, we describe the most promising small synthetic organic compounds that act as potent Sortase A inhibitors and cater the potential to be developed as antivirulence drugs. Sortase A is a polypeptide of 206 amino acids, which catalyzes two sequential reactions: (i) thioesterification and (ii) transpeptidation. Sortase A is involved in the process of bacterial adhesion by anchoring LPXTG-containing proteins to lipid II. Sortase A inhibitors do not affect bacterial growth, but they restrain the virulence of pathogenic bacterial strains, thereby preventing infections caused by Staphylococcus aureus or other Gram-positive bacteria. The efficacy of the most promising inhibitors needs to be com…

Models MolecularStaphylococcus aureusRhodanineProtein ConformationVirulenceAdamantanemedicine.disease_causeStaphylococcal infectionsSettore BIO/19 - Microbiologia GeneraleBenzoatesBacterial AdhesionSortase A inhibitors review future perspectiveMicrobiologySmall Molecule LibrariesBacterial ProteinsIn vivoDrug DiscoveryNitrilesmedicineAnimalsHumansEnzyme Inhibitorschemistry.chemical_classificationLipid IIbiologyThionesStaphylococcal Infectionsbiology.organism_classificationmedicine.diseaseAminoacyltransferasesSettore CHIM/08 - Chimica FarmaceuticaAmino acidAnti-Bacterial AgentsCysteine EndopeptidasesThiazolesBiochemistrychemistryStaphylococcus aureusSortase AMolecular MedicineBacteriaCarbolines
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What is person-centred care in dementia? Clinical reviews into practice: the development of the VIPS practice model

2013

SummaryThe VIPS framework is a four-part definition of person-centred care for people with dementia (PCC), which arose out of an earlier review article for this journal. The definition has assisted in the practical application of person-centred care. It has been operationalized into the VIPS practice model (VPM), which has been subject to a recent randomized controlled trial within Norwegian nursing homes. The VPM provided a vehicle for the VIPS framework to be utilized during reflective practice meetings focusing on understanding care situations from the perspective of residents with moderate to severe dementia. VPM incorporated an education and coaching approach, clearly defined staff rol…

Moderate to severeOperationalizationbusiness.industryReflective practicePerspective (graphical)Norwegianmedicine.diseaseCoachinglanguage.human_languagelaw.inventionNursingRandomized controlled triallawlanguageMedicineDementiaGeriatrics and GerontologybusinessGerontologyReviews in Clinical Gerontology
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Grist for Riedl's mill: A network model perspective on the integration and modularity of the human skull

2013

This research project was supported by Grant BFU2008‐00643 to D.R.G. from the Spanish Ministerio de Ciencia e Innovacion as well as project CGL2012‐37279 to M.B., from the Spanish Ministerio de Economia y Competitividad.

Modularity (networks)business.industryPerspective (graphical)BiologyHuman skullmedicine.anatomical_structureGeneticsmedicineMolecular MedicineMillAnimal Science and ZoologySoftware engineeringbusinessEcology Evolution Behavior and SystematicsDevelopmental BiologyNetwork modelJournal of Experimental Zoology Part B: Molecular and Developmental Evolution
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Moliner, C.; Cropanzano, R.; Martínez-Tur, V. (eds.) (2017). Organizational Justice: International perspectives and conceptual advances. Routledge.

2019

Moliner C.; Cropanzano R.; Martínez-Tur V. (eds.) (2017). Organizational Justice: International perspectives and conceptual advances. Routledge. ArtículoOrganizational justiceMoliner C.Cropanzano R.:PSICOLOGÍA [UNESCO]General Earth and Planetary SciencesSociologyUNESCO::PSICOLOGÍAHumanitiesInternational perspectives and conceptual advances. Routledge. Artículo [Martínez-Tur V. (eds.) (2017). Organizational Justice]General Environmental Science
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Psychology, differences & inequalities: limits & possibilities of a feminist gender perspective

2010

In this paper I propose some reflections on the role of gender perspective in the construction of the psychological knowledge, examining the implications and limitations of some of the lines developed up to the moment in this area to the treatment of differences and to answer to questions of inequality, to finally suggest some proposals to tackle the study of gender power relations and the construction of critical knowledges which could encourage the advance towards equality and social justice.

Moment (mathematics)Inequalitymedia_common.quotation_subjectWelfare economicsPerspective (graphical)Power relationsPsychology (miscellaneous)SociologySocial justicemedia_commonQuaderns de Psicologia
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Segmenting customers according to online word-of-mouth about hotels

2021

There is a renewed interest in the study of online word-of-mouth behavior due to the increasing use of the Internet and the development of social networks. This paper focuses on the receiver perspective to analyze the unequal influence of the antecedents of online consumer searches. The main purpose is to detect the heterogeneity of the effect of different motivations (convenience, risks reduction and social reassurance) and the volume of comments on the willingness to check online reviews. Based on 393 guests of hotels, a mixture regression model indicates the existence of three internally consistent segments, which reveal the varying influence on consumer intentions to look at online comm…

Motivationbusiness.industryVolumeStrategy and ManagementPerspective (graphical)Word of mouthMixture regressionAdvertisingMixture regression modelMarket segmentationHotelBenestar socialUnobserved heterogeneityHuman resource managementThe InternetEmpirical ArticleBusinessBusiness and International ManagementOnline word-of-mouthMercat InvestigacióService Business
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Cinema Letters: Queer Typography to Training Teachers in Diversity and Visual Culture

2020

This paper presents a series of proposals to innovate in the field of teacher training from a critical perspective. We use art and design education incorporating creative aspects that range from the textual discourses of visual culture (cinema) and typography to issues of sexual diversity and queer dissidences. We promote creative experiences by introducing as a reference the study of typographies designed for films that raise LGBT issues. We review the typographical tradition of design elements related to the cinema, such as posters or main titles. We approach different questions from a multidisciplinary perspective, always thinking about teacher training and also about the educational pot…

Movie theaterTypographybusiness.industryMultidisciplinary approachField (Bourdieu)Perspective (graphical)General Social SciencesQueerSociologybusinessVisual artsVisual cultureTheme (narrative)Athenea Digital. Revista de pensamiento e investigación social
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Diversity in Family Structure - Diversity in Communication Between Family Members?

2013

This study aims at investigating the parent-adolescent communication of Finnish families from a multi informant perspective. Thirteen- and fourteen-year-old adolescents (n = 171) and their parents were asked to complete a questionnaire examining positive and problematic communication between the two parties. Information about their family structure was collected. The results indicated an interrelationship between parental and adolescent assessments, particularly regarding negative aspects of communication. The boys assessed their communication with parents as more positive than did the girls. The results showed that the mothers still are the synchronizing hearts of communication in modern f…

Multi informantFamily structuremedia_common.quotation_subjectPerspective (graphical)ta516General MedicineFamily communicationPsychologySocial psychologyta515Developmental psychologyDiversity (politics)media_commonPsychology
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Multimedia application to support distance learning and other social interactions in real-time

2000

Supporting social interactions, in distance learning situations for example, with modern technology is very difficult. Generally Internet, networked PC, document handling and communication services and applications are not designed from a multiple user perspective but to support a one-person-one-device (or tool) interaction. This approach creates problems for supporting awareness of, and communication with other people while simultaneously working on documents. Such simultaneous activities have been identified as essential by CSCW and CHI studies, where users are reported to move promiscuously between media and devices, and combine applications and media intuitively, while maintaining aware…

MultimediaComputer Networks and CommunicationsHardware and ArchitectureComputer sciencebusiness.industryPerspective (graphical)Computer-supported cooperative workDistance educationThe Internetbusinesscomputer.software_genrecomputerComputer Science ApplicationsJournal of Network and Computer Applications
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Self-generated Drawing: A Help or Hindrance to Learning from Animation?

2017

The considerable potential of animations to aid learning about dynamic systems too often remains unfulfilled when the targeted subject matter is complex and unfamiliar. Various approaches designed to support learning from animation in such cases have met with limited success. Recent studies on learning from demanding texts indicate that educational outcomes can be improved if learners are required to self-generate drawings during their study of a text. This improvement has been attributed to the role of drawing in fostering deeper learner processing of the presented information and superior self-regulation as learning proceeds. It is possible that learner self-generation of drawings during …

MultimediaComputer science05 social sciencesPerspective (graphical)050301 educationAnimationcomputer.software_genre050105 experimental psychologySubject matterHuman–computer interactionDynamic visualization0501 psychology and cognitive sciences0503 educationcomputer
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