Search results for "Perte"

showing 10 items of 1643 documents

Modulation of Heart Rate by Acute or Chronic Aerobic Exercise. Potential Effects on Blood Pressure Control.

2017

It was initially assumed that heart rate and arterial blood pressure were modulated by normal respiration and muscle contraction. The arterial baroreflex, an inverse relationship between blood pressure and heart rate, was later reported. Nonetheless, it was then assumed that those responses involved vagal modulation. We summarize available evidence on the modulation of heart rate by acute or chronic aerobic exercise as well as its potential implications on blood pressure (BP) control. Numerous studies have tried to clarify whether aerobic exercise modifies neurally-mediated vasoconstriction, but they report contradictory results. In view of these incongruities, the aim of this narrative rev…

0301 basic medicinemedicine.medical_specialtyhypertensionBlood Pressureexercise; arterial baroreflex; autonomous nervous system; blood pressure; heart rate; hypertension.Disease03 medical and health sciences0302 clinical medicineHeart Rateautonomous nervous systemInternal medicineDrug DiscoveryHeart rateRespirationHeart rate variabilityMedicineAerobic exerciseAnimalsHumansCardiovascular fitnessExercisePharmacologybusiness.industryarterial baroreflex030229 sport sciences030104 developmental biologyBlood pressureCardiologymedicine.symptombusinessVasoconstrictionCurrent pharmaceutical design
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Impact of Alpha-Lipoic Acid Chronic Discontinuous Treatment in Cardiometabolic Disorders and Oxidative Stress Induced by Fructose Intake in Rats.

2019

Insulin resistance (IR) and cardiometabolic disorders are the main consequences of today&rsquo

0301 basic medicinemedicine.medical_specialtyhypertensionHomocysteinePhysiologyClinical Biochemistry030204 cardiovascular system & hematologyProtein oxidationmedicine.disease_causeBiochemistryArticleTransaminase03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInsulin resistanceDiabetes mellitusInternal medicinefructose-enriched dietinsulin resistancemedicineoxidative stressMolecular Biologybusiness.industryalpha-lipoic acidFructoseCell Biologymedicine.diseasehumanities030104 developmental biologyEndocrinologyantioxidantschemistryUric acidbusinessOxidative stressAntioxidants (Basel, Switzerland)
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The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges.

2019

The transient receptor potential ankyrin 1 (TRPA1) channel is a calcium-permeable nonselective cation channel in the plasma membrane that belongs to the transient receptor potential (TRP) channel superfamily. Recent studies have suggested that the TRPA1 channel plays an essential role in the development and progression of several cardiovascular conditions, such as atherosclerosis, heart failure, myocardial ischemia–reperfusion injury, myocardial fibrosis, arrhythmia, vasodilation, and hypertension. Activation of the TRPA1 channel has a protective effect against the development of atherosclerosis. Furthermore, TRPA1 channel activation elicits peripheral vasodilation and induces a biphasic bl…

0301 basic medicinemedicine.medical_specialtyhypertensionheart failureVasodilationReviewTRPA1 Channelarrhythmia03 medical and health sciencesTransient receptor potential channel0302 clinical medicineInternal medicinemedicineTRPA1 channelAnkyrinPharmacology (medical)vasodilationchemistry.chemical_classificationPharmacologybusiness.industrylcsh:RM1-950food and beveragesmedicine.diseaseBlockademyocardial ischemia–reperfusion injurylcsh:Therapeutics. Pharmacology030104 developmental biologyBlood pressurechemistry030220 oncology & carcinogenesisHeart failureCardiologyMyocardial fibrosismyocardial fibrosisatherosclerosisbusinesspsychological phenomena and processesFrontiers in pharmacology
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Phosphodiesterase-5 Inhibition Alleviates Pulmonary Hypertension and Basal Lamina Thickening in Rats Challenged by Chronic Hypoxia

2018

javax.xml.bind.JAXBElement@6f8948ff Hypoxia represents both an outcome of cardiopulmonary diseases and a trigger for severe pulmonary complications as pulmonary hypertension. Because nitric oxide (NO) is a critical mediator in the development of pulmonary hypertension, the modulators of its downstream function may become target of pharmacological interventions aimed at alleviating the impact of this condition. Here, we investigate the effects of an early administration of phosphodiesterase-5 inhibitor in rats where pulmonary artery hypertension was induced by chronic exposure to hypoxia. javax.xml.bind.JAXBElement@162dc677 Rats were divided into three groups: normoxic control, hypoxic with …

0301 basic medicinemedicine.medical_specialtynitrites and nitratesPhysiologySildenafilsildenafil030204 cardiovascular system & hematologyphosphodiesterase 5lcsh:PhysiologyNitric oxideendothelial NO synthase; nitric oxide; nitrites and nitrates; phosphodiesterase 5; pulmonary hypertension; pulmonary vascular remodeling; right heart failure; sildenafil03 medical and health scienceschemistry.chemical_compound0302 clinical medicinenitric oxidePhysiology (medical)medicine.arteryInternal medicinepulmonary hypertensionmedicineendothelial NO synthaseOriginal ResearchCardiopulmonary diseaseLunglcsh:QP1-981business.industryright heart failureHypoxia (medical)medicine.diseasePulmonary hypertension030104 developmental biologymedicine.anatomical_structurechemistryVentriclePulmonary arteryCardiologymedicine.symptombusinesspulmonary vascular remodelingFrontiers in Physiology
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Diagnostic and Therapeutic Approach to Sleep Disorders, High Blood Pressure and Cardiovascular Diseases. A Consensus Document by the Italian Society …

2021

Hypertension is a major contributor to fatal/nonfatal cardiovascular diseases, and timely identification and appropriate management of factors affecting hypertension and its control are mandatory public health issues. By inducing neurohormonal alterations and metabolic impairment, sleep disorders have an impact on a variety of cardiovascular risk factors, including hypertension, and ultimately increase the risk of cardiovascular events. There is evidence that qualitative and quantitative sleep disorders are associated with resistant hypertension and with impaired circadian blood pressure variations. However, sleep disturbances are often unrecognized, or heterogeneity exists in their managem…

0301 basic medicinemedicine.medical_treatmentSleep disorders.Comorbidity0302 clinical medicineCardiovascular DiseaseSleep Initiation and Maintenance DisordersInsomniaContinuous positive airway pressureSleep Apnea ObstructiveContinuous Positive Airway Pressureblood pressureHeart Disease Risk FactorPrognosisSleep in non-human animalsCircadian RhythmAntihypertensive AgentCardiovascular Diseasessleep disordersmedicine.symptomCardiology and Cardiovascular MedicineRisk assessmentHumancardiovascular riskmedicine.medical_specialtyConsensusSleep ApneahypertensionPrognosiConsensuRisk Assessment03 medical and health sciencesTherapeutic approachInternal MedicinemedicineHumansHealthy LifestyleIntensive care medicineConsensus DocumentAntihypertensive AgentsBlood pressure; Cardiovascular risk; Hypertension; Sleep disorders; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Comorbidity; Consensus; Healthy Lifestyle; Heart Disease Risk Factors; Humans; Hypertension; Prognosis; Risk Assessment; Risk Reduction Behavior; Sleep Apnea Obstructive; Sleep Initiation and Maintenance Disorders; Continuous Positive Airway Pressure; SleepSleep disorderbusiness.industryObstructivePublic healthmedicine.diseaseComorbidity030104 developmental biologyBlood pressureHeart Disease Risk Factorsblood pressure; cardiovascular risk; hypertension; sleep disordersbusinessSleepRisk Reduction Behavior030217 neurology & neurosurgery
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European contribution to the study of ROS : A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

2017

WOS: 000410470000009

0301 basic medicinereactive oxygen species ; reactive nitrogen species ; redox signaling ; oxidative stress ; antioxidants ; redox therapeuticsRedox signalingInternational CooperationSMOOTH-MUSCLE-CELLS[SDV]Life Sciences [q-bio]Clinical BiochemistryISCHEMIA-REPERFUSION INJURYReviewddc:616.07Bioinformaticsmedicine.disease_causeBiochemistryAntioxidants0302 clinical medicineENDOPLASMIC-RETICULUM STRESSCost actionlcsh:QH301-705.5ComputingMilieux_MISCELLANEOUSmedia_commonlcsh:R5-920Redox therapeuticsReactive nitrogen species3. Good healthVariety (cybernetics)MANGANESE SUPEROXIDE-DISMUTASECHRONIC GRANULOMATOUS-DISEASERisk analysis (engineering)ddc:540lcsh:Medicine (General)Oxidation-ReductionSignal TransductionSocieties ScientificPULMONARY ARTERIAL-HYPERTENSIONMedicinaEstrès oxidatiuBiology03 medical and health sciencesAntioxidants ; Oxidative Stress ; Reactive Nitrogen Species ; Reactive Oxygen Species ; Redox Signaling ; Redox TherapeuticsJournal Articlemedicinemedia_common.cataloged_instanceAnimalsHumans[CHIM]Chemical SciencesEuropean UnionEuropean unionNITRIC-OXIDE SYNTHASETANDEM MASS-SPECTROMETRYMolecular BiologyMITOCHONDRIAL OXIDATIVE STRESSGROWTH-FACTOR-BETAOrganic ChemistryDisease progressionBiology and Life SciencesOxidation reductionManganese Superoxide Dismutase030104 developmental biologylcsh:Biology (General)Oxidative stressReactive oxygen species030217 neurology & neurosurgeryOxidative stressRedox biology
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Preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% in patients with open-angle glaucoma and ocular hypertension: results of a…

2017

Lutz E Pillunat,1 Carl Erb,2 Auli Ropo,3 Friedemann Kimmich,4 Norbert Pfeiffer5 1Department of Ophthalmology, University Hospital Carl Gustav Carus, Dresden, 2Augenklinik am Wittenbergplatz, Berlin, Germany; 3Santen Europe, Helsinki, Finland; 4eyecons, Pfinztal, 5Department of Ophthalmology, Mainz University Medical Center, Mainz, Germany Background: Efficacy, tolerability and safety of the novel preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% (Taptiqom®) were investigated in an observational study in Germany.Objective: To assess efficacy, tolerability and safety of the preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% in a real-life setti…

030213 general clinical medicinemedicine.medical_specialtyIntraocular pressureOpen angle glaucomagenetic structuresfixed combinationGlaucomaTimololOcular hypertension03 medical and health sciences0302 clinical medicineOphthalmologymedicineAdverse effectOriginal Researchpreservative-free medicationbusiness.industrytafluprostTafluprostClinical Ophthalmologymedicine.diseasetimololeye diseasesOphthalmologyglaucomaTolerability030221 ophthalmology & optometrysense organspreservativesbusinessmedicine.drugClinical Ophthalmology (Auckland, N.Z.)
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Reconstitution of Myelomonocyte-Depleted Mice With Monocytes, But Not With Neutrophils, Reestablishes Arterial Hypertension and Oxidative Stress in R…

2011

0303 health sciencesmedicine.medical_specialty030309 nutrition & dieteticsbusiness.industry030302 biochemistry & molecular biologymedicine.disease_causemedicine.diseaseBiochemistry03 medical and health sciencesEndocrinologyPhysiology (medical)Pathophysiology of hypertensionInternal medicinemedicinebusinessMyelomonocyteOxidative stressFree Radical Biology and Medicine
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How to diagnose and treat abdominal compartment syndrome after endovascular and open repair of ruptured abdominal aortic aneurysms

2014

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are frequently encountered in patients treated for ruptured abdominal aortic aneurysms (rAAA) and carry a high morbidity and mortality risk. Despite these facts, IAH/ACS are still overlooked by many physicians, timely diagnosis is missed and treatment often inadequate. All staff involved in the treatment of rAAA should be aware of the risk factors predicting IAH/ACS, the profound implications and derangements on all organ systems, the clinical presentation, the appropriate measurement of intra-abdominal pressure to detect IAH/ACS and the current treatment options for these detrimental syndromes. This comprehensive r…

10042 Clinic for Diagnostic and Interventional Radiology610 Medicine & healthIntra-abdominal hypertension - Aortic aneurysm abdominal - Endovascular proceduresSettore MED/22 - Chirurgia Vascolare2705 Cardiology and Cardiovascular Medicine2746 Surgery
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In reply-Angiotensin-Converting Enzyme 2 and the Resolution of Inflammation: In Support of Continuation of Prescribed Angiotensin-Converting Enzyme I…

2020

2019-20 coronavirus outbreakAngiotensinsCoronavirus disease 2019 (COVID-19)Pneumonia ViralAngiotensin-Converting EnzymeACE2InflammationAngiotensin-Converting Enzyme InhibitorsPharmacologyArticleAngiotensin Receptor AntagonistsBetacoronavirusRenin–angiotensin systemmedicineHumansPandemicsAntihypertensive AgentsInflammationAngiotensin Receptor Antagonistsbiologybusiness.industrySARS-CoV-2COVID-19Angiotensin-converting enzymeGeneral MedicineCoronavirusAngiotensin-converting enzyme 2biology.proteinAngiotensin Receptor BlockersAngiotensin-Converting Enzyme COVID-19 coronavirus ACE2medicine.symptombusinessCoronavirus InfectionsCoronavirus InfectionsMayo Clinic proceedings
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