Search results for "Pf"
showing 10 items of 526 documents
In Vivo Nuclear Imaging of Hypoxia as Predictive Biomarkers and follow up the Response to Anti-VEGF Therapies in Idiopathic Pulmonary Fibrosis
2022
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal disease of unknown origin. In France, it is one of the most common interstitial pathologies (IP) and affects 4,400 new people each year. IPF is characterized by dysregulated healing mechanisms that lead to the accumulation of large amounts of collagen in the lung tissue and cause disorganization of the alveolar architecture. It results in progressive deterioration of the respiratory function, leading in a few years to chronic respiratory failure and then to death. Idiopathic pulmonary fibrosis has a lower survival rate than many cancers with a median survival of 2 to 5 years from diagnosis. This pathology whose main ris…
Development of the Pixel Detector for the Belle II experiment and top quark mass measurement in radiative events at the future electron-positron line…
2019
Durante los últimos cien años, los numerosos descubrimientos en los colisionadores de partículas y desarrollos teóricos han conducido a los físicos de partículas a construir el Modelo Estándar, el modelo teórico más exitoso hasta la fecha. Sin embargo, a pesar de su gran éxito, el Modelo Estándar no describe toda la fenomenología observada actualmente en los diferentes experimentos. Es por ello que se necesitan nuevos colisionadores que proporcionen observaciones de nueva física que nos ayuden a construir modelos que describan dicha fenomenología. Para enfrentarse al reto, la comunidad de física de partículas se une formando grandes colaboraciones, con el propósito de diseñar y construir lo…
Cucumis sativus l. Seeds ameliorate muscular spasm-induced gastrointestinal and respiratory disorders by simultaneously inhibiting calcium mediated s…
2021
Cucumis sativus L. is globally cultivated as an edible vegetable. Besides its nutritional benefits, it is used in traditional medicines against various ailments. The current study was designed to elucidate the multi-target mechanisms of a C. sativus seeds extract against asthma and diarrhea using network pharmacology along with a molecular docking approach. Furthermore, in-vitro and in-vivo experiments were conducted to verify the mechanistic insight of in silico studies. LC-ESI-MS/MS was performed to identify the bioactive compounds in the extract; later, some compounds were quantified by HPLC. C. sativus seed. EtOH has kaempferol in higher concentration 783.02 µg/g, followed by quercetin …
Measurements of anterior chamber depth, white-to-white distance, anterior chamber angle, and pupil diameter using two Scheimpflug imaging devices.
2014
Purpose: To compare the ocular anterior chamber depth, white-to-white distance, anterior chamber angle, and pupil diameter, as measured with two different Scheimpflug imaging devices. Methods: This transversal study included 80 right eyes from 80 subjects aged from 20 to 40 years. Their spherical equivalents ranged from -4.25 to +1.00 diopters (D). Each eye's anterior chamber depth, white-to-white distance, anterior chamber angle, and pupil diameter, were measured for far vision using both the Galilei G4 (double Scheimpflug camera) and the Pentacam HR (single Scheimpflug camera) systems. Results: Mean anterior chamber depths were calculated as 3.12 ± 0.23 mm and 3.19 ± 0.24 mm when measured…
Preliminary data revealing efficacy of Streptococcus salivarius K12 (SSK12) in Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adeniti…
2023
ObjectiveTo evaluate the potential role of Streptococcus salivarius K12 (SSK12) in controlling febrile flares in patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Further aims were to assess the impact of SSK12 on (i) flare duration, (ii) variation in the degree of the highest body temperature during flares, (iii) steroid-sparing effect, and (iv) change of PFAPA accompanying symptoms before and after SSK12 introduction.Patients and methodsThe medical charts from 85 pediatric patients with PFAPA syndrome (49 males and 36 females) enrolled in the AIDA registry and treated with SSK12 for a median period of 6.00 ± 7.00 months in the period b…
Ionic liquid crystals based on 3-perfluoalkyl-1,2,4-triazol-4-ium salts
2016
Liquid-crystalline ionic liquids (LC-ILs) are a class of organic materials that of great current interest: they are defined as organic salts that possess the properties of two interesting kinds of material – ionic liquids (ILs) and liquid crystals (LCs). LC-ILs combine many interesting features of ILs (e.g. low volatility and the ability to dissolve solutes with a range of polarities) as well as many attractive properties of LCs (e.g. their intrinsic order and anisotropy). This provides unique opportunities that can be exploited in many different fields, for example their use as solvents for extraction processes as well as electrolytes for batteries, fuel cells, and dye-sensitised solar cel…
Validation of the German version of the Kujala score in patients with patellofemoral instability : a prospective multi-centre study
2017
Introduction: The Kujala score is the most frequently used questionnaire for patellofemoral disorders like pain, instability or osteoarthritis. Unfortunately, we are not aware of a validated German version of the Kujala score. The aim of our study was the translation and linguistic validation of the Kujala score in German-speaking patients with patella instability and the assessment of its measurement characteristics. Materials and methods: The German Kujala score was developed in several steps of translation. In addition to healthy controls, the Kujala German was assessed in consecutive patients undergoing reconstruction of the medial patellofemoral ligament for recurrent patellar dislocat…
Recent Advances in Kaempferia Phytochemistry and Biological Activity : A Comprehensive Review
2019
Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely used in traditional medicines to cure metabolic disorders, inflammation, urinary tract infections, fevers, coughs, hypertension, erectile dysfunction, abdominal and gastrointestinal ailments, asthma, wounds, rheumatism, epilepsy, and skin diseases. Objective: Herein, we reported a comprehensive review, including the traditional applications, biological and pharmacological advances, and phytochemical constituents of Kaempheria species from 1972 up to early 2019. Materials and methods: All the information and reported stu…
Vēsturiskā kamera herbāriju ievākšanai
2019
19. gadsimtā par botāniķu lauka darbu ierastu aprīkojumumu kļuva no metāla izgatavota kamera herbārija uzglabāšanai (‘vasculum’). Latvijas Universitātes Muzeja Botānikas un mikoloģijas kolekcijās glabājas ne tikai šādas kameras lietojuma liecības fotogrāfijās, bet arī pati kamera.
Karla Reinholda Kupfera herbāriju saraksts
2019
1929. gadā dabaspētnieks Karls Reinholds Kupfers (1872 – 1935) pārdeva Latvijas Universitātei savu herbāriju, kas bija izvietots skapjos, kam klāt bija kolektora sastādīts saraksts. Šobrīd LU Muzeja Botānikas un Mikoloģijas kolekcijās glabājas ne tikai šis aptuveni 26 700 lapu lielais herbārijs, kas veido Herbarium Balticum (starptautiskais kods RIG I), bet arī zinātnieka skapji, kuros izvietots K. R. Kupfera mantojuma apakškolekcija.