Search results for "Phenanthrene"

showing 10 items of 101 documents

CCDC 783766: Experimental Crystal Structure Determination

2011

Related Article: V.Blanco, M.D.Garcia, A.Terenzi, E.Pia, A.Fernandez-Mato, C.Peinador, J.M.Quintela|2010|Chem.-Eur.J.|16|12373|doi:10.1002/chem.201002051

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersbis(mu~2~-2-(4-(4-pyridylmethyl)phenyl)-27-diazapyrenium)-bis(ethylenediamine)-di-platinum(ii) hexakis(hexafluorophosphate) phenanthrene clathrate acetonitrile solvateExperimental 3D Coordinates
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CCDC 2074636: Experimental Crystal Structure Determination

2021

Related Article: Jaroslav Jacko, Monika Staś, Lubomír Rulíšek, Ivana Císařová, Martin Kotora|2022|J.Org.Chem.|87|744|doi:10.1021/acs.joc.1c01118

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterstribenzo[1112:34:78]cyclododeca[12-l]phenanthrene benzene unknown solvateExperimental 3D Coordinates
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CCDC 766950: Experimental Crystal Structure Determination

2010

Related Article: S.Ikonen, Nonappa, A.Valkonen, R.Juvonen, H.Salo, E.Kolehmainen|2010|Org.Biomol.Chem.|8|2784|doi:10.1039/c003228j

Space GroupCrystallographyCrystal SystemCrystal StructureDimethyl 44'-(1010'''1313'''-tetramethyldotriacontahydrotrispiro[cyclopenta[a]phenanthrene-32'-[13]dioxane-5'5''-[13]dioxane-2''3'''-cyclopenta[a]phenanthrene]-1717'''-diyl)dipentanoateCell ParametersExperimental 3D Coordinates
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CCDC 910388: Experimental Crystal Structure Determination

2013

Related Article: Y.Inokuma,S.Yoshioka,J.Ariyoshi,T.Arai,Y.Hitora,K.Takada,S.Matsunaga,K.Rissanen,M.Fujita|2013|Nature (London)|495|461|doi:10.1038/nature11990

Space GroupCrystallographyCrystal Systemcatena-[bis(mu~3~-246-tris(Pyridin-4-yl)-135-triazine)-hexakis(iodo)-tri-zinc(ii) 9-bromophenanthrene clathrate unknown solvate]Crystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2074635: Experimental Crystal Structure Determination

2021

Related Article: Jaroslav Jacko, Monika Staś, Lubomír Rulíšek, Ivana Císařová, Martin Kotora|2022|J.Org.Chem.|87|744|doi:10.1021/acs.joc.1c01118

Space GroupCrystallographyCrystal Systemtribenzo[1112:34:78]cyclododeca[12-l]phenanthrene benzene solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 804367: Experimental Crystal Structure Determination

2015

Related Article: Kathrin Wehming, Moritz Schubert, Gregor Schnakenburg, Siegfried R. Waldvogel|2014|Chem.-Eur.J.|20|12463|doi:10.1002/chem.201403442

Space GroupCrystallographyethyl 4-bromo-2367-tetramethoxyphenanthrene-9-carboxylateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor.

2013

Abstract Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new drugs acting at the dopamine receptors (DR) as potential new targets for the treatment of schizophrenia or Parkinson’s disease. Previous studies have revealed that isoquinoline compounds such as tetrahydroisoquinolines (THIQs) can behave as selective D 2 dopaminergic alkaloids. In the present study we have synthesized five aporphine compounds and five phenanthrene alkaloids and evaluated their potential dopaminergic activity. Binding studies on rat striatal membranes were used to evaluate their affinity and…

StereochemistryClinical BiochemistryPharmaceutical ScienceNeurotransmissionPharmacologyBiochemistryMethylenedioxychemistry.chemical_compoundAlkaloidsDrug DiscoveryAnimalsHumansAporphineIsoquinolineMolecular BiologyChemistryReceptors Dopamine D2Organic ChemistryDopaminergicParkinson DiseasePhenanthrenePhenanthrenesCorpus StriatumRatsDopamine receptorSchizophreniaMolecular MedicineSelectivityBioorganicmedicinal chemistry letters
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Synthesis of Polyfused Heterocycle Derivatives Containing the Dipyridoimidazole Core by Friedländer’s Reaction: Access to Analogs of Ellipticine

2005

Reaction of 3-amino-2-formylimidazo[l,2-a]pyridine with various aldehydes and ketones by Friedlander's methodology afforded an entry to dipyridoimidazole, tri(tetra)azacyclopenta[b]fluorene, tri(tetra)azabenzo[b]-fluorene and triazaindeno[2,1-b]phenanthrene derivatives. Intercalation with a synthetic oligodeoxynucleotide was examined.

StereochemistryIntercalation (chemistry)[CHIM.THER]Chemical Sciences/Medicinal ChemistryFluorene010402 general chemistry01 natural sciencesAnalytical ChemistryEllipticinechemistry.chemical_compound[ CHIM.ORGA ] Chemical Sciences/Organic chemistryPyridine[CHIM.COOR]Chemical Sciences/Coordination chemistryComputingMilieux_MISCELLANEOUSPharmacologybiology[CHIM.ORGA]Chemical Sciences/Organic chemistry010405 organic chemistryOrganic Chemistry[ CHIM.COOR ] Chemical Sciences/Coordination chemistry[ CHIM.THER ] Chemical Sciences/Medicinal ChemistryPhenanthrenebiology.organism_classification0104 chemical scienceschemistryTetra[ CHIM.RADIO ] Chemical Sciences/Radiochemistry[CHIM.RADIO]Chemical Sciences/RadiochemistryHETEROCYCLES
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Differential Enantioselectivity of Murine GlutathioneS-Transferase Isoenzymes in the Glutathione Conjugation ofTrans-3,4-dihydroxy-1,2-oxy- 1,2,3,4-t…

1998

Abstract The kinetics of the glutathione (GSH) conjugation of (+)- and (−)-enantiomers ofanti- as well assyn-3,4-dihydroxy-1,2-oxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene (B[c]PDE) catalyzed by murine GSHS-transferase (GST) isoenzymes has been investigated. Murine GSTs exhibited significant differences in their enantioselectivity toward B[c]PDE stereoisomers. For example, while pi class isoenzyme mGSTP1-1 was virtually inactive toward stereoisomers with 1Sconfiguration [(−)-syn-and (+)-anti-B[c]PDE], these stereoisomers were good substrates for alpha class isoenzyme mGSTA1-2. When GST activity was measured as a function of varying B[c]PDE concentration (10–320 μM) at a fixed saturating conce…

StereochemistryKineticsBiophysicsAlpha (ethology)BiochemistryIsozymeCatalysisSubstrate SpecificityMicechemistry.chemical_compoundPiAnimalsheterocyclic compoundsMolecular BiologyCarcinogenGlutathione TransferaseStereoisomerismGlutathionePhenanthrenesPhenanthrenemusculoskeletal systemGlutathioneCarcinogens EnvironmentalIsoenzymesKineticschemistrysense organsEnantiomerArchives of Biochemistry and Biophysics
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DFT studies of COOH tip-functionalized zigzag and armchair single wall carbon nanotubes

2011

Structure and energy calculations of pristine and COOH-modified model single wall carbon nanotubes (SWCNTs) of different length were performed at B3LYP/6-31G* level of theory. From 1 to 9 COOH groups were added at the end of the nanotube. The differences in structure and energetics of partially and fully functionalized SWCNTs at one end of the nanotube are observed. Up to nine COOH groups could be added at one end of (9,0) zigzag SWCNT in case of full functionalization. However, for (5,5) armchair SWCNT, the full functionalization was impossible due to steric crowding and rim deformation. The dependence of substituent attachment energy on the number of substituents at the carbon nanotube ri…

Steric effectsNanotubeMaterials scienceBiomedicine generalCarboxylic AcidsSubstituentHealth InformaticsCarbon nanotubeDFTCatalysislaw.inventionEnd-substitutionInorganic Chemistrychemistry.chemical_compoundCarboxylation energylawOrganic chemistryComputer SimulationComputer Applications in ChemistryPhysical and Theoretical ChemistryAnthracenesLife Sciences generalOriginal PaperNanotubes CarbonOrganic ChemistryZigzag and armchair SWCNTBenzoic AcidPhenanthrenesComputer Science ApplicationsChemistryCrystallographyModels ChemicalComputational Theory and MathematicschemistryZigzagComputer Appl. in Life SciencesQuantum TheoryThermodynamicsMolecular MedicineSurface modificationCOOH functionalization
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