Search results for "Phene"

showing 10 items of 863 documents

2016

The title compound, C32H48O8P2S2, was prepared by the nickel-catalyzed reaction of bis(5-bromothienyl)dipropoxybenzene and triisopropyl phosphite. The thiophene rings are inclined to the benzene ring by 14.6 (2) and 25.3 (3)°. One propyloxy group is disordered. Four hydrogen bonds connect the molecules, which are arranged in ribbons parallel to thebcplane.

010405 organic chemistryStereochemistryHydrogen bondGeneral MedicineCrystal structure010403 inorganic & nuclear chemistryRing (chemistry)01 natural sciencesPhosphonateMedicinal chemistry0104 chemical scienceschemistry.chemical_compoundchemistryThiopheneBenzeneIUCrData
researchProduct

Chemical composition, herbicidal and antifungal activity of Satureja cuneifolia essential oils from Spain

2016

The chemical composition of essential oils from Satureja cuneifolia growing in east Spain was analyzed by GC, GC/MS. Forty-five compounds accounting for 99.1% of the total oil were identified. Camphor (47.6%), followed by camphene (13.6%) were the main compounds. Their herbicidal and antifungal activity was tested in vitro against three weeds (Amaranthus hybridus, Portulaca oleracea and Conyza canadensis) and eleven common pathogenic or saprophytic fungi (Phytophthora citrophthora, P. palmivora, Pythium litorale, Verticillium dahlia, Rhizoctonia solani, Penicillium hirsutum, Colletotrichum gloeosporioides, Phaeoacremonium aleophilum, Phaemoniella chlamydospora, Cylindrocarpon liriodendri a…

0106 biological sciencesHerbicidal activityAntifungal AgentsPhytophthora citrophthoraAmaranthus hybridusBOTANICAPlant WeedsGerminationPlant Science01 natural sciencesEssential oillaw.inventionRhizoctonia solanichemistry.chemical_compoundlawDrug DiscoveryOils VolatileAntifungal activityEssential oilSatureja cuneifoliaPharmacologyCylindrocarponBIOLOGIA VEGETALbiologyHerbicidesPlant ExtractsSaturejaFungiGeneral MedicineVerticilliumbiology.organism_classification0104 chemical sciencesPhaeoacremonium aleophilum010404 medicinal & biomolecular chemistryHorticultureComplementary and alternative medicinechemistrySpainCamphene010606 plant biology & botany
researchProduct

Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mP…

2016

Dopamine D2 receptors (D2R) in the medial prefrontal cortex (mPFC) are key players in the etiology and therapeutics of schizophrenia. The overactivation of these receptors contributes to mPFC dysfunction. Chronic treatment with D2R agonists modifies the expression of molecules implicated in neuronal structural plasticity, synaptic function, and inhibitory neurotransmission, which are also altered in schizophrenia. These changes are dependent on the expression of the polysialylated form of the neural cell adhesion molecule (PSA-NCAM), a plasticity-related molecule, but nothing is known about the effects of D2R and PSA-NCAM on excitatory neurotransmission and the structure of mPFC pyramidal n…

0301 basic medicineAgonistMaleDendritic spineArticle SubjectGlycoside Hydrolasesmedicine.drug_classDendritic SpinesPrefrontal CortexNeural Cell Adhesion Molecule L1NeurotransmissionInhibitory postsynaptic potentialbehavioral disciplines and activitiesSynaptic Transmissionlcsh:RC321-571Rats Sprague-Dawley03 medical and health sciences0302 clinical medicineDopamineDopamine receptor D2PhenethylaminesmedicineAnimalslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryChemistryReceptors Dopamine D2Pyramidal CellsGlutamate receptorRats030104 developmental biologyNeurologynervous systemDopamine AgonistsSialic AcidsNeural cell adhesion moleculeNeurology (clinical)Neuroscience030217 neurology & neurosurgerymedicine.drugResearch ArticleNeural plasticity
researchProduct

Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation

2016

Signal Transducer and Activator of Transcription 5 (STAT5) protein, a component of the STAT family of signaling proteins, is considered to be an attractive therapeutic target because of its involvement in the progression of acute myeloid leukemia. In an effort to discover potent molecules able to inhibit the phosphorylation-activation of STAT5, twenty-two compounds were synthesized and evaluated on the basis of our knowledge of the activity of 2-(3’,4’,5’-trimethoxybenzoyl)-3-iodoacetamido-6-methoxy benzo[b]furan derivative 1 as a potent STAT5 inhibitor. Most of these molecules, structurally related to compound 1, were characterized by the presence of a common 3’,4’,5’-trimethoxybenzoyl moi…

0301 basic medicineApoptosisAntineoplastic Agentchemistry.chemical_compoundBenzophenone0302 clinical medicinehemic and lymphatic diseasesFuranDrug DiscoverySTAT5 Transcription FactorTumor Cells CulturedThiopheneMoietyPhosphorylationSTAT5Molecular StructurebiologyChemistryBiological activityGeneral MedicineApoptosis; BCR/ABL expressing leukemia; In vitro antiproliferative activity; STAT5 inhibitors; Structure-activity relationship; Drug Discovery3003 Pharmaceutical Science; Organic Chemistry; PharmacologyLeukemia Myeloid Acute030220 oncology & carcinogenesisBCR/ABL expressing leukemiaApoptosis; BCR/ABL expressing leukemia; In vitro antiproliferative activity; STAT5 inhibitors; Structure-activity relationship; Antineoplastic Agents; Apoptosis; Benzofurans; Benzophenones; Cell Proliferation; Dose-Response Relationship Drug; Drug Screening Assays Antitumor; Humans; K562 Cells; Leukemia Myeloid Acute; Molecular Structure; Phosphorylation; STAT5 Transcription Factor; Structure-Activity Relationship; Tumor Cells Cultured; Drug Discovery3003 Pharmaceutical Science; Organic Chemistry; PharmacologyHumanStereochemistryAntineoplastic AgentsArticleNOBenzophenones03 medical and health sciencesK562 CellHumansStructure–activity relationshipBenzofuransCell ProliferationPharmacologyIndole testDose-Response Relationship DrugIn vitro antiproliferative activitySTAT5 inhibitorsDrug Discovery3003 Pharmaceutical ScienceOrganic ChemistryApoptosiSTAT5 inhibitorStructure-activity relationshipIn vitro030104 developmental biologybiology.proteinBenzofuranDrug Screening Assays AntitumorK562 Cells
researchProduct

Aza-macrocyclic triphenylamine ligands for G-quadruplex recognition

2018

A new series of triphenylamine-based ligands with one (TPA1PY), two (TPA2PY) or three pendant aza-macrocycle(s) (TPA3PY) has been synthesised and studied by means of pH-metric titrations, UV/Vis spectroscopy and fluorescence experiments. The affinity of these ligands for G-quadruplex (G4) DNA and the selectivity they show for G4s over duplex DNA were investigated by Forster resonance energy transfer (FRET) melting assays, fluorimetric titrations and circular dichroism spectroscopy. Interestingly, the interactions of the bi- and especially the tri-branched ligands with G4s lead to a very intense redshifted fluorescence emission band that may be associated with intermolecular aggregation betw…

0301 basic medicineCircular dichroismaggregation-induced emissionChemistry Multidisciplinaryamines010402 general chemistryG-quadruplexTriphenylamine01 natural sciencesCatalysisCIRCULAR-DICHROISM03 medical and health scienceschemistry.chemical_compoundGeneral chemistryfluorescent probestriphenylamine polyaminesMoleculeSpectroscopyFLUORESCENT-PROBESScience & TechnologyG-quadruplexChemistryINTRAMOLECULAR CHARGE-TRANSFERANTICANCER DRUG DESIGNOrganic ChemistryaggregationFORMING REGIONDNAGeneral ChemistryFluorescenceG-quadruplexes0104 chemical sciencesCrystallographyChemistry030104 developmental biologyFörster resonance energy transfer2-PHOTON ABSORPTIONPROMOTER REGIONPhysical SciencesEQUILIBRIUM-CONSTANTSGRAPHENE OXIDE03 Chemical Sciencesmacrocyclic ligands
researchProduct

Metabolic and process engineering for biodesulfurization in Gram-negative bacteria

2017

32 p.-2 fig.-1 tab.

0301 basic medicineFossil FuelsGram-negative bacteriaScale-up030106 microbiologychemistry.chemical_elementBioengineeringThiophenesBiologyApplied Microbiology and BiotechnologyMetabolic engineering03 medical and health scienceschemistry.chemical_compoundPseudomonasOperonProcess engineering2. Zero hungerSulfur Compoundsbusiness.industryPseudomonasGeneral Medicinebiology.organism_classificationSulfurEnvironmentally friendly6. Clean waterKineticsBiodesulfurizationBiodegradation EnvironmentalchemistryDibenzothiopheneGram-negative bacteriaGenetic engineeringbusinessOrganosulfur compoundsMetabolic engineeringBacteriaMetabolic Networks and PathwaysDibenzothiopheneBiotechnology
researchProduct

Mapping brain activity with flexible graphene micro-transistors

2016

arXiv:1611.05693v1.-- et al.

0301 basic medicineMaterials scienceFOS: Physical sciences02 engineering and technologylaw.invention03 medical and health scienceslawGeneral Materials ScienceElectronicsPhysics - Biological PhysicsNeural implantsBioelectronicsBioelectronicsbusiness.industryGrapheneSensorsMechanical EngineeringTransistorGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsField-effect transistorsMicroelectrodeBrain implant030104 developmental biologyBiological Physics (physics.bio-ph)Mechanics of MaterialsFOS: Biological sciencesQuantitative Biology - Neurons and CognitionOptoelectronicsNeurons and Cognition (q-bio.NC)Charge carrierField-effect transistorGraphene0210 nano-technologybusiness2D Materials
researchProduct

Evaluation of permeability applicability based on continuum mechanics law in fluid flow through graphene membrane

2019

AbstractGraphene is expected to be used in separation applications such as desalination. However, it is difficult to predict the flow phenomena at the nanoscale using the conventional continuum law. Particularly at a Knudsen number (Kn) of >0.1, which is applied in filtration, it has been reported that not even slip boundary conditions can be applied. In this study, to identify the parameters that affect the applicability of the continuum law, we conducted a fluid permeation simulation using graphene. The deviation of the permeability from that of the continuum model was calculated by changing the channel width, fluid temperature, and fluid type. The result showed that the channel width …

0301 basic medicineNanoscale materialsMultidisciplinaryMaterials scienceContinuum mechanicsContinuum (measurement)lcsh:Rlcsh:MedicineSlip (materials science)PermeationArticleMechanical engineering03 medical and health sciencesPermeability (earth sciences)030104 developmental biology0302 clinical medicineLawFluid dynamicslcsh:QKnudsen numberBoundary value problemGraphenelcsh:Science030217 neurology & neurosurgeryScientific Reports
researchProduct

Effect of graphene substrate type on formation of Bi2Se3 nanoplates

2019

AbstractKnowledge of nucleation and further growth of Bi2Se3 nanoplates on different substrates is crucial for obtaining ultrathin nanostructures and films of this material by physical vapour deposition technique. In this work, Bi2Se3 nanoplates were deposited under the same experimental conditions on different types of graphene substrates (as-transferred and post-annealed chemical vapour deposition grown monolayer graphene, monolayer graphene grown on silicon carbide substrate). Dimensions of the nanoplates deposited on graphene substrates were compared with the dimensions of the nanoplates deposited on mechanically exfoliated mica and highly ordered pyrolytic graphite flakes used as refer…

0301 basic medicineNanostructureMaterials scienceNucleationlcsh:MedicineSubstrate (electronics)Chemical vapor depositionTOPOLOGICAL INSULATORGRAIN-BOUNDARIESArticlelaw.invention03 medical and health scienceschemistry.chemical_compoundTHIN-FILMS0302 clinical medicinelawSilicon carbide[CHIM]Chemical SciencesPyrolytic carbonThin filmlcsh:ScienceMultidisciplinaryGraphenelcsh:R030104 developmental biologySINGLEchemistryChemical engineeringGROWTHlcsh:Q030217 neurology & neurosurgeryScientific Reports
researchProduct

Carbon based nanomaterials for tissue engineering of bone: Building new bone on small black scaffolds: A review.

2019

Graphical abstract

0301 basic medicineScaffoldCarbon nanotubesNanotechnologyCarbon nanotubeReview ArticleBone tissuelaw.inventionNanodiamondsScaffold03 medical and health sciences0302 clinical medicineTissue engineeringlawBone cellmedicineCarbon dotsTissue engineeringlcsh:Science (General)BoneCarbon nanomaterialsComputingMethodologies_COMPUTERGRAPHICSGraphene oxidelcsh:R5-920MultidisciplinaryChemistryRegeneration (biology)030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisCarbon nanomaterialsFullerenesStem celllcsh:Medicine (General)lcsh:Q1-390Journal of advanced research
researchProduct