Search results for "Phenolic"

showing 10 items of 200 documents

In Vitro Cytotoxic Effect of Aqueous Extracts from Leaves and Rhizomes of the Seagrass Posidonia oceanica (L.) Delile on HepG2 Liver Cancer Cells: Fo…

2023

Aqueous extracts from Posidonia oceanica’s green and brown (beached) leaves and rhizomes were prepared, submitted to phenolic compound and proteomic analysis, and examined for their potential cytotoxic effect on HepG2 liver cancer cells in culture. The chosen endpoints related to survival and death were cell viability and locomotory behavior, cell-cycle analysis, apoptosis and autophagy, mitochondrial membrane polarization, and cell redox state. Here, we show that 24 h exposure to both green-leaf- and rhizome-derived extracts decreased tumor cell number in a dose–response manner, with a mean half maximal inhibitory concentration (IC50) estimated at 83 and 11.5 μg of dry extract/mL, respecti…

phenolic compoundreactive oxygen specieSettore CHIM/10 - Chimica Degli AlimentiGeneral Immunology and MicrobiologycaspaseSettore BIO/05 - Zoologiaproteomic analysiscell biology; cell cycle; reactive oxygen species; wound healing assay; caspases; mitochondrial transmembrane potential; clonogenic assay; phenolic compounds; proteomic analysisGeneral Biochemistry Genetics and Molecular Biologycell biologymitochondrial transmembrane potentialcell cycleclonogenic assaySettore BIO/06 - Anatomia Comparata E CitologiaGeneral Agricultural and Biological Scienceswound healing assayBiology
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Phenolic composition and antioxidant activity in freshly squeezed blood and blond orange juices [citrus sinensis (l.) Osbeck].

2007

phenolics compounds ORAC citrusSettore AGR/15 - Scienze E Tecnologie Alimentari
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Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspec…

2019

Abstract Corylus avellana (hazelnut) is one of the most popular tree nuts on a worldwide basis. The main products of C. avellana are kernels, a nutritious food, with a high content of healthy lipids, contained in a hard shell. In recent years, along with the ongoing research carried out on hazelnut kernels, a growing interest has been addressed to the hazelnut byproducts including hazelnut skin, hazelnut hard shell, and hazelnut green leafy cover as well as hazelnut tree leaf. These byproducts deriving from the roasting, cracking, shelling/hulling, and harvesting processes have been found as a source of “phytochemicals” with biological activity. The aim of this review is to provide a compre…

phenolicsPharmaceutical ScienceAntineoplastic Agents01 natural sciencesNutritious foodAnalytical ChemistryHuman healthCorylusAnti-Infective AgentsBetulaceaeDrug Discoveryanalytical tools; Betulaceae; biological activities; Corylus avellana; diarylheptanoids; phenolics; taxanes; Animals; Anti-Infective Agents; Antineoplastic Agents; Antipain; Corylus; Humans; Nuts; Plant ExtractsAnimalsAntipainHumansNutsFood scienceHazelnut treeBeneficial effectsRoastingPharmacology010405 organic chemistryChemistryPlant ExtractsOrganic Chemistrybiological activitiestaxanes0104 chemical sciences010404 medicinal & biomolecular chemistrydiarylheptanoidsComplementary and alternative medicineMolecular Medicineanalytical toolsCorylus avellana
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Use of Biostimulants for Organic Apple Production: Effects on Tree Growth, Yield, and Fruit Quality at Harvest and During Storage

2018

The experiment was conducted during two consecutive seasons (years 2016 and 2017) in an organic apple orchard of the cultivar Jonathan. Several biostimulants were tested (10 in total), including humic acids, macro and micro seaweed extracts, alfalfa protein hydrolysate, amino acids alone or in combination with zinc, B-group vitamins, chitosan and a commercial product containing silicon. Treatments were performed at weekly intervals, starting from the end of May until mid-August. The macroseaweed extract was effective in stimulate tree growth potential in both years, as shown by a significantly larger leaf area (+20% as compared to control) and by an higher chlorophyll content and leaf photo…

photosynthesisorganic productionMalus × domesticaphysiological disordersfungiseaweed extractfood and beverageslcsh:SB1-1110Plant Sciencephenolic compoundslcsh:Plant cultureanthocyaninsOriginal ResearchFrontiers in Plant Science
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Solar UV radiation and plant responses : assessing the methodological problems in research concerning stratospheric ozone depletion

2010

plant phenolicsBetulaceaeaction spectrahajoaminenvaikutusspektritotsonikatoultraviolettisäteilylitter decompositionkarikefenoliset yhdisteetvasteetsoil respirationUV-säteily
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An Endemic Plant of the Mediterranean Area: Phytochemical Characterization of Strawberry Tree (Arbutus unedo L.) Fruits Extracts at Different Ripenin…

2022

This work focused on the extraction, quantification, and characterization of bioactive compounds of Arbutus unedo L. fruits, comparing the results obtained from the different ripening states. Extractions were performed by different methods (such as maceration extraction and ultrasonic extraction) and food grade solvents (aqueous and hydroalcoholic solvents) in each of the all ripening states (four states considered, associated with four different colors, i.e., green, yellow, orange, and red). The presence of (poly)phenols was quantified and characterized, and scavenging activity was determined by the Folin–Ciocâlteu reagent and the DPPH method, respectively. The content of bioactive compoun…

radical scavenging activitiesSettore BIO/01 - Botanica GeneraleMRM mass spectrometryNutrition and DieteticsSettore BIO/02 - Botanica SistematicaEndocrinology Diabetes and Metabolismtotal phenolic compoundsSettore BIO/03 - Botanica Ambientale E Applicataripening processArbutus unedo LFood ScienceFrontiers in Nutrition
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Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species

2022

Distillation is the most widely used method to obtain an essential oil from plant material. The biomass used in the process is returned as a solid residue together with variable amounts of water rich in water-soluble compounds, which currently are not addressed to any further application. The scope of this work was to evaluate the phytochemical composition of wastewaters coming from hydrodistillation (DWWs) of five aromatic plants belonging to the Lamiaceae family, and to assess their in vitro antioxidant and anti-inflammatory activities. The phenolic profiles of the DWWs were determined by HPLC-DAD and HPLC-ESI/MS. Free radical scavenging ability, oxygen radical antioxidant capacity and su…

radical scavengingrosmarinic aciddistillation wastes; phenolic profile; rosmarinic acid; intestinal inflammation; anti-inflammatory; radical scavenging; antioxidantantioxidantLamiaceaePlant ExtractsSettore AGR/13 - Chimica AgrariaPhytochemicalsOrganic ChemistryAnti-Inflammatory AgentsWaterPharmaceutical ScienceWastewaterphenolic profileAntioxidantsSettore AGR/02 - Agronomia E Coltivazioni ErbaceeAnalytical ChemistryPhenolsChemistry (miscellaneous)intestinal inflammationDrug DiscoveryMolecular Medicinedistillation wastePhysical and Theoretical Chemistryanti-inflammatoryMolecules
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Development of high-performance thin layer chromatography method for identification of phenolic compounds and quantification of rosmarinic acid conte…

2020

ABSTRACT Aim: Representatives of Nepetoideae Burnett subfamily are promising species of the Lamiaceae Martinov family because of accumulating such valuable groups of secondary metabolites as terpenoids and polyphenols. A high-performance thin layer chromatography (HPTLC) fingerprint method for the qualitative determination of phenolic compounds and for the quantification of rosmarinic acid (RA) content in methanol extracts of five species of this subfamily was developed for the first time. Materials and Methods: Dried aerial parts of Dracocephalum moldavica L., Ocimum americanum L., Lophanthus anisatus (Nutt.) Benth., Monarda fistulosa L., and Satureja hortensis L. collected in flowering pe…

rosmarinic acidlcsh:Analytical chemistrylcsh:RS1-441BioengineeringGeneral Biochemistry Genetics and Molecular Biologylamiaceaelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compound0302 clinical medicineChlorogenic acidCaffeic acid030212 general & internal medicineHigh performance thin layer chromatographyGeneral Pharmacology Toxicology and PharmaceuticsDracocephalum moldavicaphenolic compoundChromatographylcsh:QD71-142biologyRosmarinic acidchromatographic fingerprints030206 dentistrybiology.organism_classificationhigh-performance thin layer chromatographyThin-layer chromatographyOcimum americanumchemistryOriginal ArticleLamiaceaeJournal of Pharmacy and Bioallied Sciences
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Polyphenols and Pharmacological Screening of a Monarda fistulosa L. dry Extract Based on a Hydrodistilled Residue By-Product

2021

This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evaluate its safety and pharmacological properties. The total phenolic content (TPC) in the MFDE was 120.64 mg GAE/g. The high-performance liquid chromatography (HPLC) analysis showed the presence of a plethora of phenolic compounds, including hydroxycinnamic acids and flavone derivatives in the MFDE, with rosmarinic acid and luteolin-7-O-glucoside being the main components. With an IC50 value of 0.285 mg/mL, it was found to be a strong DPPH radical scavenger. …

safetyDPPHRM1-950phenolic compoundsMonarda fistulosa01 natural sciencesHigh-performance liquid chromatographywild bergamot03 medical and health scienceschemistry.chemical_compound0302 clinical medicineantiradical activityPharmacology (medical)anti-inflammatory activityanalgesic activityOriginal ResearchPharmacologyResidue (complex analysis)biologyTraditional medicine010405 organic chemistryRosmarinic acidbiology.organism_classificationAcute toxicity0104 chemical scienceschemistryherbPolyphenol030220 oncology & carcinogenesispostdistillation wasteLamiaceaeTherapeutics. PharmacologyFrontiers in Pharmacology
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Antioxidant phenolic compounds in Salvia officinalis L. and Salvia sclarea L.

2018

The differences in the chemical composition of the phenolic compounds of Salvia officinalis versus Salvia sclarea growing in different habitats, were studied. First, the optimal solvent - methanol - for ultrasonic extraction of phenolic compounds from these plants was chosen experimentally. Total phenolic content and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays were determined spectrophotometrically. Total phenolic content was in the range of 63.9 to 134.4 mg GAE/g of plant depending on the studied species. The highest antiradical activity was displayed by the methanol fractions of S. sclarea varieties (83 and 67%). HPLC-DAD analysis of extracts was done in order to identify the presence of …

sageSalvia officinalis L.clary sagephenolic compoundsSalvia sclarea L.Ecological Chemistry and Engineering S-Chemia I Inzynieria Ekologiczna S
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