Search results for "Philosophy of Science"

The Soluble Interleukin-6 Receptora

2006

Feedback Mechanisms between ?2M and TGF?1 Reduce Extracellular Matrix Synthesis of Liver Fat-Storing Cells

1994

La lucha por el mantenimiento de un huerto de simples en la universidad de Valencia durante el siglo XVII

2005

This article deepens on the efforts made during the 17th century by Medicine professors and students, Pharmacist Associations as well as surgeons and magistrates from Valencia directed toward the creation and mantenaince of a garden destinated to the growing of medicinal plants from worldwide.

In Vitro Effects of Antiphospholipid Syndrome-IgG Fractions and Human Monoclonal Antiphospholipid IgG Antibody on Human Umbilical Vein Endothelial Ce…

2009

It has been shown that stimulation of endothelial cells and monocytes by antiphospholipid antibodies leads to a prothrombotic state involving upregulation of tissue factor (TF). We examined the in vitro effects of IgG fractions from patients with antiphospholipid syndrome (APS) and of a β-2-glycoprotein 1-independent human monoclonal antiphospholipid antibody (HL-5B) on human umbilical vein endothelial cells (HUVEC) in comparison to untreated cell controls and to exposure to monoclonal IgG control antibody. We also examined the effect of recombinant monocyte chemoattractant protein-1 (MCP-1) on peripheral blood monocytes. Stimulation of endothelial cells with APS IgG fractions or HL-5B resu…

Estadística en física de partícules: El seu paper en el descobriment del bosó de Higgs

2014

L’estadistica ha representat un paper d’enorme importancia en el desenvolupament de la fisica de particules, pionera de l’anomenada «gran ciencia». La seua aplicacio ha evolucionat al compas dels progressos tecnologics, que han permes passar de registrar uns pocs centenars de «successos» a registrar-ne milers de milions. Aquest article discuteix sobre com s’ha resolt el problema de la manipulacio d’aquestes quantitats massives de dades i com s’han utilitzat les principals eines estadistiques des dels anys 1990 per a cercar senyals cada vegada mes petits ocults entre un soroll de fons cada vegada major. Molts experiments en la historia de la fisica de particules podrien il·lustrar el paper q…

Neurosis y Gastralgia según Juan Bta. Peset y Vidal (1869)

1998

The article consist of two parts. The first is a summary of the treaty in which the main ideas about diseases analysed by the doctor Peset and Vidal are presented. The second part is a comparative analysis of the text for which the author has consulted many books and other material of those days, as well as medical dictionaries. As a result of it, the author presents the "gastralgia" as a digestive neurosis.

New glucocorticoids. Mechanisms of immunological activity at the cellular level and in the clinical setting.

1990

El Gran Catharro de 1580 ¿gripe o pertussis?

2005

The gran Catharro (1580) is considered the first influenza epidemic. The analysis of various testimonies of the time may offer some doubts about whether or not it was so; and data strongly support that it was a pertussis epidemic.

Transport, stability, and biological activity of resveratrol

2011

Numerous studies have reported interesting properties of trans-resveratrol, a phytoalexin, as a preventive agent of several important pathologies: vascular diseases, cancers, viral infections, and neurodegenerative processes. These beneficial effects of resveratrol have been supported by observations at the cellular and molecular levels in both cellular and in vivo models, but the cellular fate of resveratrol remains unclear. We suggest here that resveratrol uptake, metabolism, and stability of the parent molecule could influence the biological effects of resveratrol. It appears that resveratrol stability involves redox reactions and biotransformation that influence its antioxidant properti…

Capillary Rise in Nanotubes Coated with Polymer Brushes

2009

The spontaneous rise of a fluid in a brush-coated nanocapillary is studied by molecular dynamics simulation of a coarse-grained model. The cases of changing wettability of both the capillary walls and the brush were examined. We also investigated the impact of polymer chain length on the transport of fluid along the nanotube. We found that capillary filling takes place in both lyophilic and lyophobic tubes, provided that the polymer brush coating is wetted by the fluid. In all the cases studied, capillary rise proceeds by a time-square law, but the mechanisms behind them (Lucas-Washburn or diffusive propagation) differ, depending on the chain length N. For a wettable wall, the speed of flui…