Search results for "Picrates"

showing 10 items of 21 documents

Phytochemical profiles, phototoxic and antioxidant properties of eleven Hypericum species - A comparative study

2018

Hypericum is one out of the nine genera belonging to the botanical family Clusiaceae Lindl (syn. Hypericaceae Juss.; APG III, 2009). The genus contains 484 species spread worldwide, one of which, Hypericum perforatum, is largely used in folk medicine. The aim of this study was to evaluate the chemical composition, along with the antioxidant and phototoxic activity, of 11 Hypericum species grown in Sicily (H. perforatum L., H. aegypticum L., H. androsaemum L., H. calycinum L., H. hircinum L., H. hirsutum L., H. montanum L., H. patulum Thunb., H. perfoliatum L., H. pubescens Boiss., H. tetrapterum Fr.). Samples of flowering tops collected from these Hypericum species were extracted and analys…

0106 biological sciencesDPPHHyperforinAntioxidants Hyperforin Hypericin Hypericum species (Clusiaceae Lindl.) Phototoxicity; PolyphenolsPhytochemicalsHypericinFlowersPlant ScienceHorticultureHypericaceae01 natural sciencesBiochemistryAntioxidantsMass SpectrometryPhototoxicityMicechemistry.chemical_compoundPicratesSpecies SpecificityHypericum species (Clusiaceae Lindl.) Phototoxicity Polyphenols Hypericin Hyperforin AntioxidantsAnimalsHypericum species (Clusiaceae Lindl.)Molecular BiologyChromatography High Pressure LiquidbiologyTraditional medicine010405 organic chemistryChemistryBiphenyl CompoundsPolyphenolsHypericum perforatumGeneral MedicineFibroblastsbiology.organism_classificationSettore AGR/02 - Agronomia E Coltivazioni Erbacee0104 chemical sciencesHypericinHyperforinPhotochemotherapyPhytochemicalPolyphenolNIH 3T3 CellsAntioxidantReactive Oxygen SpeciesHypericumHypericumDermatitis Phototoxic010606 plant biology & botany
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The Application of a Plant Biostimulant Based on Seaweed and Yeast Extract Improved Tomato Fruit Development and Quality

2020

Plant biostimulants are under investigation as innovative products to improve plant production and fruit quality, without resulting in environmental and food contaminations. Here, the effects of the application of Expando, a biostimulant based on seaweed and yeast extracts, on plant productivity, fruit ripening times, and fruit quality of Solanum lycopersicum var. Micro-Tom were evaluated. After biostimulant treatment, a two-week reduction of ripening times and a concomitant enhancement of the production percentage during the earliest ripening times, in terms of both fruit yield (+110%) and size (+85%), were observed. Concerning fruit quality, proximate analysis showed that tomatoes treated…

0106 biological sciencesDPPHPhytochemicalslcsh:QR1-50201 natural sciencesBiochemistryripening timeAntioxidantslcsh:Microbiologychemistry.chemical_compoundSolanum lycopersicumSettore BIO/10 - BiochimicaYeastsSettore BIO/04 - Fisiologia Vegetale0303 health sciencesMineralsABTSbiologyChemistry<i>Solanum lycopersicum</i>carotenoidsfood and beveragesRipeningfruit sizeBioactive compoundLycopeneHorticulturetocopherolsmineral contentArticle03 medical and health sciencesNutraceuticalPicratesYeast extractBenzothiazolesMolecular Biologypolyphenols030304 developmental biologySolanum lycopersicum; carotenoids; fruit quality; fruit size; lycopene; mineral content; polyphenols; ripening time; tocopherolsBiphenyl Compoundsfungifruit qualitybiology.organism_classificationSeaweedlycopeneFruitCarotenoids Fruit quality Lycopene Mineral content Polyphenols Ripening time Solanum lycopersicum TocopherolsSolanumSulfonic Acids010606 plant biology & botany
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Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Act…

2018

Citrus fruits are often employed as ingredients for functional drinks. Among Citrus, the variety, &#8220;Lempso&#8222;, a typical hybrid of the Calabria region (Southern Italy), has been reported to possess superior antioxidant activity when compared to other common Citrus varieties. For these reasons, the aim of this study is to investigate in vitro the nutraceutical value of the Tarocco clone, &#8220;Lempso&#8222;, highlighting its anti-inflammatory and antioxidant potential. A post-column 2,2&#8242;-diphenyl-1-picrylhydrazyl (DPPH&#8226;) radical scavenging assay for the screening of antioxidant compounds in these complex matrices was developed. Subsequently, polyphenolic extract was tes…

0301 basic medicineAnthocyaninAntioxidantDPPHMacrophagemedicine.medical_treatmentAnti-Inflammatory AgentsPharmacologyAntioxidantschemistry.chemical_compoundMiceoxidative stressCitrus sinensiNutrition and DieteticsbiologyNF-kappa Bon-line HPLC-DPPHanthocyaninsNitric oxide synthaseBiphenyl compoundAnti-Inflammatory AgentCytokinesAntioxidantmacrophages J774A.1lcsh:Nutrition. Foods and food supplyCitrus × sinensisCitrus sinensisLPSmedicine.drug_classCell SurvivalNF-E2-Related Factor 2lcsh:TX341-641Anti-inflammatoryArticleNitric oxidePlant ExtractCell LineAnthocyanins; LPS; Macrophages J774A.1; On-line HPLC-DPPH; Oxidative stress; Food Science; Nutrition and Dietetics03 medical and health sciencesNutraceuticalPicratesmedicineAnimalsCytokineanthocyanins; LPS; macrophages J774A.1; on-line HPLC-DPPH; oxidative stressoxidative streAnimalPlant ExtractsMacrophagesBiphenyl CompoundsPolyphenolsSettore CHIM/08 - Chimica Farmaceutica030104 developmental biologychemistrybiology.proteinBiphenyl CompoundPicrateFood ScienceNutrients
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From Ecology to Biotechnology, Study of the Defense Strategies of Algae and Halophytes (from Trapani Saltworks, NW Sicily) with a Focus on Antioxidan…

2019

This study aimed at the characterization of the antioxidant power of polyphenol extracts (PE) obtained from the algae Cystoseira foeniculacea (CYS) (Phaeophyta) and from the halophyte Halocnemum strobilaceum (HAL), growing in the solar saltworks of western Sicily (Italy), and at the evaluation of their anti-microfouling properties, in order to correlate these activities to defense strategies in extreme environmental conditions. The antioxidant properties were assessed in the PE based on the total antioxidant activity test and the reducing power test

0301 basic medicineDPPH[CHIM.THER]Chemical Sciences/Medicinal Chemistry<i>Cystoseira foeniculacea</i>010501 environmental sciences01 natural sciencesAntioxidantsAnti-oxidantlcsh:Chemistrychemistry.chemical_compoundcrude extractsMarine bacteriophageAnti-Infective Agentslipid oxidationbiodimarCystoseira foeniculacea<i>Halocnemum strobilaceum</i>brown algaFood scienceGallic acidSicilylcsh:QH301-705.5SpectroscopyEcologybiologyanti-microbialmarine-bacteriaantifoulingHalocnemum strobilaceumSalt-Tolerant PlantsGeneral MedicineClosteriumComputer Science Applicationsseaweedscystoseiraradical-scavenging activityBiotechnologyMicrobial Sensitivity TestsPhaeophytaArticleCatalysisInorganic Chemistry03 medical and health sciencesantifouling activitiesPicratesAlgaeLipid oxidationDefense14. Life underwaterPhysical and Theoretical ChemistryMolecular BiologyShellfishpolyphenols0105 earth and related environmental sciencesBacteriaACLBiphenyl CompoundsOrganic Chemistrybiology.organism_classificationdefenses030104 developmental biologychemistrylcsh:Biology (General)lcsh:QD1-99913. Climate actionPolyphenolanti-oxidantsseasonal-variation[SDE.BE]Environmental Sciences/Biodiversity and Ecologyphenolic compositionInternational Journal of Molecular Sciences
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Synthesis and antioxidant evaluation of novel silybin analogues

2006

In this work, we evaluated the antioxidant properties of the eight novel silybin analogues for their capacity to scavenge free radicals including superoxide anion radicals and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals in vitro. Compound 7d demonstrated an excellent antioxidant effect in scavenging superoxide anion free radical with an IC50 value of 26.5 microM, while the IC50 of quercetin (the reference compound) was 38.1 microM. Compounds 7b, 7e, 7h showed certain scavenging activities for both types of free radicals.

AnionsAntioxidantDPPHRadicalmedicine.medical_treatmentDrug Evaluation PreclinicalMedicinal chemistryAntioxidantsInhibitory Concentration 50chemistry.chemical_compoundPicratesSuperoxidesDrug DiscoverymedicineOrganic chemistryIC50PharmacologyDose-Response Relationship DrugSuperoxideBiphenyl CompoundsAnion radicalsFree Radical ScavengersGeneral MedicineIn vitroHydrazinesModels ChemicalchemistrySpectrophotometrySilybinQuercetinQuercetinSilymarinJournal of Enzyme Inhibition and Medicinal Chemistry
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The Antioxidant Potential of White Wines Relies on the Chemistry of Sulfur-Containing Compounds: An Optimized DPPH Assay

2019

The DPPH (2,2-Diphenyl-1-picrylhydrazyl) assay is an easy and efficient method commonly used to determine the antioxidant capacity of many food matrices and beverages. In contrast with red wines, white wines are poorer in antioxidant polyphenolics, and the more hydrophilic sulfur-containing compounds in them may contribute significantly to their antioxidant capacity. The modification of the classical DPPH method, with a methanol-buffer and the measure of EC20 (quantity of sample needed to decrease the initial DPPH concentration by 20%) has shown that sulfur-containing compounds such as cysteine (0.037 &plusmn

AntioxidantDPPHmedicine.medical_treatmentPharmaceutical ScienceMethanethiolWineantioxidant capacity01 natural sciencesAntioxidantsCatechinAnalytical ChemistryEC<sub>20</sub>Ferulic acidchemistry.chemical_compoundcaractérisation sensorielleDrug Discovery[SDV.IDA]Life Sciences [q-bio]/Food engineeringCaffeic acidFood sciencefood and beveragesCatechinChimical engineering04 agricultural and veterinary sciences040401 food science3. Good healthChemistryChemistry (miscellaneous)Alimentation et NutritionMolecular Medicinesulfur compoundscapacité antioxydanteCoumaric AcidsDPPH;antioxidant capacity;Chardonnay;white wine;EC20;sensory oxidation level;sulfur compoundswhite winesensory oxidation levelChardonnayArticlelcsh:QD241-4410404 agricultural biotechnologyCaffeic Acidslcsh:Organic chemistryPhenolsPicratesmedicineEC20Food and NutritionGénie chimiqueHumansPhysical and Theoretical ChemistryBiologyvin blanc010401 analytical chemistryOrganic ChemistryBiphenyl CompoundsGlutathione0104 chemical sciencesHigh-Throughput Screening AssayschemistryPolyphenolDPPHMolecules
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Antioxidant and neuroprotective effects of synthesized sintenin derivatives

2009

Three series of sintenin derivatives (compounds 1-14) were designed and prepared and their antioxidative and neuroprotective effects were evaluated. The in vitro models of scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, chelating ferrous ions, inhibiting the rat brain homogenates lipid peroxidation, and protecting neurons damaged by hydrogen peroxide were employed for bioassays. It was found that sintenin derivatives 4 and 13 showed remarkable antioxidative and neuroprotective activities.

AntioxidantDPPHmedicine.medical_treatmentRadicalNeuroprotectionAntioxidantsRats Sprague-DawleyLipid peroxidationchemistry.chemical_compoundPicratesDrug DiscoverymedicineAnimalsChelationHydrogen peroxideCells CulturedChelating AgentsNeuronsPharmacologyChemistryBiphenyl CompoundsHydrogen PeroxideGeneral MedicineRatsBiphenyl compoundNeuroprotective AgentsBiochemistryLipid PeroxidationPropionatesJournal of Enzyme Inhibition and Medicinal Chemistry
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In Vitro Phytotoxicity and Antioxidant Activity of Selected Flavonoids

2012

Made available in DSpace on 2013-09-27T14:54:27Z (GMT). No. of bitstreams: 1 WOS000306186200008.pdf: 228949 bytes, checksum: 818c9c7c18b61f5827cc5873d4eed670 (MD5) Previous issue date: 2012-05-01 Made available in DSpace on 2013-09-30T18:36:37Z (GMT). No. of bitstreams: 1 WOS000306186200008.pdf: 228949 bytes, checksum: 818c9c7c18b61f5827cc5873d4eed670 (MD5) Previous issue date: 2012-05-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:48:50Z No. of bitstreams: 1 WOS000306186200008.pdf: 228949 bytes, checksum: 818c9c7c18b61f5827cc5873d4eed670 (MD5) Made available in DSpace on 2014-05-20T13:48:50Z (GMT). No. of bitstreams: 1 WOS000306186200008.pdf: …

AntioxidantDPPHmedicine.medical_treatmentantioxidant activityMorinflavonoids; germination; radical elongation; antioxidant activity; structure/activityBiologyArticlestructure/activityAntioxidantsLepidium sativumCatalysisRaphanusInorganic Chemistrychemistry.chemical_compoundPicratesBotanymedicineheterocyclic compoundsFood sciencePhysical and Theoretical ChemistryMolecular BiologySpectroscopyFlavonoidsBiphenyl CompoundsfungiOrganic Chemistryfood and beveragesBiological activityCatechinGeneral MedicineComputer Science Applicationsradical elongationBiphenyl compoundgerminationchemistryflavonoidsQuercetinLuteolinInternational Journal of Molecular Sciences
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Succinobucol’s New Coat — Conjugation with Steroids to Alter Its Drug Effect and Bioavailability

2011

Synthesis, detailed structural characterization (X-ray, NMR, MS, IR, elemental analysis), and studies of toxicity, antioxidant activity and bioavailability of unique potent anti-atherosclerotic succinobucol-steroid conjugates are reported. The conjugates consist of, on one side, the therapeutically important drug succinobucol ([4-{2,6-di-tert-butyl-4-[(1-{[3-tert-butyl-4-hydroxy-5-(propan-2-yl)phenyl]sulfanyl}ethyl)sulfanyl]phenoxy}-4-oxo-butanoic acid]) possessing an antioxidant and anti-inflammatory activity, and on the other side, plant stanol/sterols (stigmastanol, β-sitosterol and stigmasterol) possessing an ability to lower the blood cholesterol level. A cholesterol-succinobucol prodr…

AntioxidantFree RadicalsStereochemistrymedicine.medical_treatmentStatic ElectricityAnti-Inflammatory AgentsBiological AvailabilityPharmaceutical ScienceprobucolArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441Micechemistry.chemical_compoundPicrateslcsh:Organic chemistrySulfanylDrug DiscoverymedicineAnimalsHumansPhysical and Theoretical Chemistrysuccinobucol; phytosterol; atherosclerosis; cholesterol; probucolta317phytosterolStigmastanolClinical Trials as TopicMice Inbred BALB CMolecular StructurePhytosterolBiphenyl CompoundsOrganic Chemistrycholesterol3T3 CellsFibroblastsProdrugAscorbic acidBioavailabilityBiphenyl compoundchemistryChemistry (miscellaneous)Molecular MedicineSteroidsatherosclerosissuccinobucolMolecules; Volume 16; Issue 11; Pages: 9404-9420
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Polyphenol Characterization, Antioxidant and Skin Whitening Properties of Alnus cordata Stem Bark

2019

In this study, we investigated the phenolic composition of the crude extract (MeOH 80 %) of Alnus cordata (Loisel.) Duby stem bark (ACE) and its antioxidant and skin whitening properties. RP-LC-DAD analysis showed a high content of hydroxycinnamic acids (47.64 %), flavanones (26.74 %) and diarylheptanoids (17.69 %). Furthermore, ACE exhibited a dose-dependent antioxidant and free-radical scavenging activity, expressed as half-maximal inhibitory concentration (IC50 ): Oxygen radical absorbance capacity (ORAC, IC50 1.78 μg mL-1 )>Trolox equivalent antioxidant capacity (TEAC, IC50 3.47 μg mL-1 )>2,2-Diphenyl-1-picrylhydrazyl (DPPH, IC50 5.83 μg mL-1 )>β-carotene bleaching (IC50 11.58 μg mL-1 )…

AntioxidantOxygen radical absorbance capacityDPPHmedicine.medical_treatmentTrolox equivalent antioxidant capacityBioengineeringAlnus cordata; antimelanogenic activity; Betulaceae; mushroom tyrosinase; polyphenols; RP-LC-DAD analysis; zebrafish; Alnus; Animals; Antioxidants; Biphenyl Compounds; Enzyme Inhibitors; Monophenol Monooxygenase; Picrates; Plant Bark; Plant Extracts; Polyphenols; Skin; ZebrafishAlnus01 natural sciencesBiochemistryAntioxidantschemistry.chemical_compoundPicratesmedicineAnimalsFood scienceEnzyme InhibitorsMolecular BiologyIC50ZebrafishSkinbiologyMonophenol MonooxygenasePlant Extracts010405 organic chemistryBiphenyl CompoundsPolyphenolsSkin whiteningGeneral ChemistryGeneral Medicinebiology.organism_classificationAlnus cordata0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryPolyphenolPlant BarkMolecular Medicine
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