Search results for "Pill"

Amplificazione real-time allele-specifica per l'individuazione della mutazione V600E del B-RAF nel carcinoma papillare su agoaspirato tiroideo.

2005

Detection of BRAFv600E mutation in papillary thyroid carcinoma using real time allele-specific amplification on fine needle aspiration biopsy specime…

2006

Analytical methods to determine cocaine contamination of banknotes from around the world

2008

Abstract The presence of cocaine in a significant number of UK pounds (Xxxx), Euros (€) and North American banknotes ($) in general circulation requires appropriate tools to do determinations. This article discusses the-state-of-the-art in the analysis of cocaine on banknotes. We summarize the usual extraction methods of currency samples and compare them, especially with respect to avoiding sample damage. We critically discuss analytical methods, namely gas chromatography (GC) and liquid chromatography (LC), capillary electrophoresis (CE), immunoassay, thermal desorption tandem mass spectrometry (TD-MS2) and ion-mobility spectrometry (IMS). We also review cocaine levels on banknotes around …

The Gabal Gerf complex: A precambrian N-MORB ophiolite in the Nubian Shield, NE Africa

1995

We report geochemical and isotopic data for tectonically dismembered units of the Cabal Gerf mafic-ultramafic complex, the largest Neoproterozoic (Pan-African) ophiolite in the Arabian-Nubian Shield and located near the Red Sea in the border region between Egypt and the Sudan. The complex consists of basaltic pillow lavas, sheeted dykes, isotropic and layered gabbros and an ultramafic melange, all in tectonic contact along thrust sheets. Major- and trace-element data, including REE, for the pillow lavas and sheeted dykes are indistinguishable from modem high-Ti N-MORB. Chemical variations in the various rock types can be ascribed to fractionation and accumulation involving olivine, clinopyr…

Petrography, mineralogy and geochemistry of a primitive pumice from Stromboli: implications for the deep feeding system

2011

We describe the field relations, petrographic, mineralogical and geochemical characteristics of an exceptional “ golden ” pumice belonging to a tephra layer exposed on the summit area of Stromboli volcano, Italy. Pumice sample PST-9 comes from a fallout deposit older than a spatter agglutinate sequence emplaced during the twentieth century. The eruption that produced it had a size exceeding that of intermediate paroxysms but was smaller than large-scale, spatter-forming, paroxysms from the sixteenth century and 1930 A.D. Lapilli are strongly vesicular and crystal-poor, similar to other “ golden ” pumices. Modal proportions include 89 vol% glass, 8 vol% clinopyroxene, 1–2 vol% olivine and 1–…

Crystal Structure and Host-Guest Binding Ability of Three Types of Pillar[5]arenes

2015

A systematic research of the structural characterization and the host-guest binding abilities between three types of pillar[5]arenes 3–5 (3 for Structure Type I, 4 for Structure Type II and 5 for Structure Type III) is carried out by 1H NMR measurements and X-ray study. The results show that the configurations or symmetry of their cavities not only have large difference in these three types of pillar[5]arenes, but also have more or less variations even in the same structure type or the same host locked different guests such as crystals of 3a–3b, 4a–4d. On the other hand, the complexation behavior of pillar[5]arenes with 1,4-dibromobutane (DBB) is affected by the different symmetrical struct…

Reactivity of anticancer metallodrugs with serum proteins: New insights from size exclusion chromatography-ICP-MS and ESI-MS

2010

International audience; A method based on the coupling of high resolution size-exclusion liquid chromatography using a polymer stationary phase with inductively coupled plasma mass spectrometry was developed to study the interactions of two metallodrugs - cisplatin and RAPTA-T - with the serum proteins albumin and transferrin. In contrast to previous approaches, the technique allowed the total recovery of the metals from the column and was able to discriminate between the different species of the metallodrugs and their complexes with the proteins at femtomolar detection levels. Metal binding was found to be dependent on the protein concentration and on the incubation time of the sample. Cis…

Finite Size Effects in Thin Film Simulations

2003

Phase transitions in thin films are discussed, with an emphasis on Ising-type systems (liquid-gas transition in slit-like pores, unmixing transition in thin films, orderdisorder transitions on thin magnetic films, etc.) The typical simulation geometry then is a L xL x D system, where at the low confining L x L surfaces appropriate boundary “fields” are applied, while in the lateral directions periodic boundary conditions are used. In the z-direction normal to the film, the order parameter always is inhomogeneous, due to the boundary “fields” at the confining surfaces. When one varies the temperature T from the region of the bulk disordered phase to a temperature below the critical temperatu…

Molecular Dynamics simulation of evaporation processes of fluid bridges confined in slit-like pore

2009

A simple fluid, described by point-like particles interacting via the Lennard-Jones potential, is considered under confinement in a slit geometry between two walls at distance Lz apart for densities inside the vapor-liquid coexistence curve. Equilibrium then requires the coexistence of a liquid "bridge" between the two walls, and vapor in the remaining pore volume. We study this equilibrium for several choices of the wall-fluid interaction (corresponding to the full range from complete wetting to complete drying, for a macroscopically thick film), and consider also the kinetics of state changes in such a system. In particular, we study how this equilibrium is established by diffusion proces…

Combination of supported liquid membrane and solid-phase extraction for sample pretreatment of triazine herbicides in juice prior to capillary electr…

2002

A possibility of a combination of supported liquid membrane (SLM) and solid-phase extraction (SPE) for the determination of atrazine at microgram level in different type of fruit juices is presented. In comparison to SPE extraction from juice samples, the application of SLM-SPE enrichment provides much cleaner extracts and the possibility of lowering the limit of detection as low as 30 microg/l. However, it was also shown that by appropriate manipulation of SLM extraction conditions mainly flow-rate of donor phase and volume ratio between donor and acceptor phase, the level of detection can be further decreased to 10 microg/l. The results suggest that the application of SLM extraction prior…