Search results for "Pill"
showing 10 items of 1870 documents
Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE-MS
2009
10 páginas, 2 figuras, 4 tablas.
TOPS-MODE approach for the prediction of blood-brain barrier permeation.
2004
The blood-brain barrier permeation has been investigated by using a topological substructural molecular design approach (TOPS-MODE). A linear regression model was developed to predict the in vivo blood-brain partitioning coefficient on a data set of 119 compounds, treated as the logarithm of the blood-brain concentration ratio. The final model explained the 70% of the variance and it was validated through the use of an external validation set (33 compounds of the 119, MAE = 0.33), a leave-one-out crossvalidation (q(2) = 0.65, S(press) = 0.43), fivefold full crossvalidation (removing 28 compounds in each cycle, MAE = 33, RMSE = 0.43) and the prediction of +/- values for an external test set …
Pupillometry as a measure for listening effort in children: a review
2020
Listening effort can be defined as the deliberate allocation of mental resources to overcome obstacles when carrying out a listening task. Requiring mental resources, it may detract from other type...
SOLID-PHASE EXTRACTION OF PESTICIDES FROM WATER SAMPLES
1990
Patterns of Intention: Royal chapels in the Crown of Aragon (fourteenth-fifteenth centuries) and the Capilla de los Reyes in the Convent of Saint Dom…
2020
El propósito de este estudio es reconsiderar la Capilla de los Reyes en el convento de Santo Domingo, sus posibles funciones y valorar las intenciones de esta fundación de Alfonso V, rey de Aragón, Sicilia y Nápoles. Esta excepcional capilla, célebre por sus bóvedas aristadas de piedra gris, fue construida por el maestro Francesc Baldomar entre 1439 y 1463 y se adscribía a una tradición de lugares de oración asociados a las residencias reales en diversas ciudades de la Corona de Aragón, una entidad compuesta por tres reinos y un principado unidos por el gobierno de una única dinastía. En un período de realeza itinerante era imperativo mostrar magnificencia no sólo en palacios y residencias,…
Tidal notches, coastal landforms and relative sea-level changes during the Late Quaternary at Ustica Island (Tyrrhenian Sea, Italy)
2017
In this paper we present and discuss data concerning the morphostructural evolution at Ustica Island (Tyrrhenian Sea, Italy) during Late Quaternary. New insights on the relative sea-level changes of Ustica are coming from data collected during a geomorphological field survey around the island, together with the bathymetric analysis of the surrounding seabed and 14C datings on samples of speleothems, flowstones and marine shells found inside three selected sea caves. The survey was mainly accomplished on June 2015 through the first complete snorkel investigation off the about 18 km-long volcanic coast of the island, which allowed to precisely define location, relationship and morphometric fe…
COMPARATIVE STUDY ON THE ELECTROPHYSIOLOGICAL EFFECTS OF MONENSIN ON ATRIAL AND VENTRICULAR MUSCLE PREPARATIONS OF GUINEA-PIG HEART
1995
The effects of monensin (10 µmol/L) alone and in presence of verapamil (3 µmol/L) or ouabuin (1 µmol/L) or glibenclamide (10 µmol/L) or BaCl2 separately were studied on the electrophysiological properties represented by force of contraction, duration of action potential, and membrane resting potential of isolated atrial and ventricular muscle of guinea –pig heart. Monensin induced a transient increase in the force of contraction of atrial and ventricular muscles. It caused a decrease in action potential duration of papillary muscle, this effect was reversed by glibenclamide. Monensin increased the action potential duration of atrial muscle in absence or presence of glibenclamide. In presenc…
Evidence of thin-film precursors formation in hydrokinetic and atomistic simulations of nano-channel capillary filling
2008
We present hydrokinetic Lattice Boltzmann and Molecular Dynamics simulations of capillary filling of high-wetting fluids in nano-channels, which provide clear evidence of the formation of thin precursor films, moving ahead of the main capillary front. The dynamics of the precursor films is found to obey the Lucas-Washburn law as the main capillary front, z2(t) proportional to t, although with a larger prefactor, which we find to take the same value for both geometries under inspection. Both hydrokinetic and Molecular Dynamics approaches indicate a precursor film thickness of the order of one tenth of the capillary diameter. The quantitative agreement between the hydrokinetic and atomistic m…
Assignment of complex species by affinity capillary electrophoresis: The case of Th(IV)‐desferrioxamine B
2020
International audience; The electrophoretic mobility change of desferrioxamine B (DFO) was monitored by UV absorption spectrophotometry upon increasing the thorium(IV) concentration in the background electrolyte at two acidities ([HClO4]Tot = 0.0316 and 0.0100 M). These data enabled to assess the speciation model and to determine the equilibrium constant of [Th(DFO)H2]3+ at fixed ionic strength (I = 0.1 M (H,Na)ClO4). Affinity capillary electrophoresis (ACE) turned out to be most helpful in identifying the complexed species by ascertaining its charge and protonation state. The assignment of the correct stoichiometry relied on the reliable estimation of the electrophoretic mobility by assumi…
Desktop X-ray tomography for low contrast samples
2013
Abstract Based on the experience in the use of polycapillary optical systems, recently XLab Frascati LNF and IM CNR have been strongly involved in studying the techniques for high resolution X-ray Imaging and micro-tomography that intends in the development of a new imaging instrument to examine low contrast samples complicated by fast developing processes. In order to get the reliable signal to noise ratio, typically available via synchrotron radiation (SR) dedicated X-ray optical devices, for the desktop solutions we have to increase the radiation fluxes from conventional sources. As known, manipulated through polycapillary optics beams result in getting higher fluxes with respect to a pi…