Search results for "Pilot Project"

showing 10 items of 492 documents

rTMS of the prefrontal cortex in the treatment of chronic migraine: a pilot study

2004

A recent fMRI study showed that dorsolateral prefrontal cortex (DLPFC) exerts an inhibitory control on pain pathways in humans. We investigated whether high-frequency rTMS over left DLPFC could ameliorate chronic migraine. Treatment consisted of 12 rTMS sessions, delivered in alternate days over left DLPFC. Sham rTMS was used as placebo. Eleven patients were randomly assigned to the rTMS (n=6) or to the placebo (n=5) treatment. Measures of attack frequency, headache index, number of abortive medications (outcome measures) were recorded in the month before, during and in the month after treatment. Subjects treated by rTMS showed a significant reduction of the outcome measures during and in t…

AdultMaleTime FactorsKindligMigraine DisordersPrefrontal CortexPilot ProjectsPlacebobehavioral disciplines and activitieslaw.inventionCentral nervous system diseaseMagneticsChronic MigraineDouble-Blind MethodRandomized controlled triallawmental disordersrTMSmedicineHumansPrefrontal cortexChronic migrainePsychiatric Status Rating ScalesAnalysis of VarianceHeadacheMigraine prophylaxiMiddle Agedmedicine.diseaseElectric StimulationClinical trialDorsolateral prefrontal cortexTreatment Outcomemedicine.anatomical_structurenervous systemNeurologyMigraineAnesthesiaCortico-lymbic sensitizationChronic DiseaseFemaleLeft dorsolateral prefrontal cortexNeurology (clinical)Psychologypsychological phenomena and processes
researchProduct

Exposure assessment approach through mycotoxin/creatinine ratio evaluation in urine by GC–MS/MS

2014

Abstract In this pilot survey human urine samples were analyzed for presence of 15 mycotoxins and some of their metabolites using a novel urinary multi-mycotoxin GC–MS/MS method following salting-out liquid–liquid extraction. Fifty-four urine samples from children and adults residents in Valencia were analyzed for presence of urinary mycotoxin and expressed in gram of creatinine. Three out of 15 mycotoxins were detected namely, HT-2 toxin, nivalenol and deoxynivalenol (DON). 37 samples showed quantifiable values of mycotoxins. Co-occurrence of these contaminants was also observed in 20.4% of assayed samples. DON was the most frequently detected mycotoxin (68.5%) with mean levels of 23.3 μg/…

AdultMaleTolerable daily intakeChromatography GasAdolescentUrinary systemFood ContaminationPilot ProjectsUrineToxicologymedicine.disease_causeYoung Adultchemistry.chemical_compoundLimit of DetectionTandem Mass SpectrometrymedicineHumansFood scienceChildMycotoxinExposure assessmentCreatinineChromatographyChemistryToxinReproducibility of Resultsfood and beveragesGeneral MedicineMycotoxinsT-2 ToxinCreatinineFood MicrobiologyFemaleGas chromatography–mass spectrometryTrichothecenesFood ScienceFood and Chemical Toxicology
researchProduct

Country and gender differences in the motivation of dental students - An international comparison

2018

PURPOSE The objective of this study, conducted in Germany, Finland and Turkey, was to identify whether motivations to study dentistry varied by country, gender or year of study. METHODS The multicentre pilot study was conducted in English language in 2014. Participants (n = 469 dental students) were either in the first or last year of study. The response rate was 91%. RESULTS The sample comprised 63% females and 37% males, reflecting the common gender distribution in dental education. A total of 236 first year students (50.3%) and 233 final year students (49.7%) took part in the study. The participants were aged 21-25 years and of 15 different nationalities, mostly from Turkey, Germany and …

AdultMaleTurkeyTurkishStudents DentalFriendsPilot ProjectsEducationGermanYoung Adult03 medical and health sciences0302 clinical medicineGermanySurveys and QuestionnairesHumansFamilyTime managementHealth Workforce030212 general & internal medicineEducation DentalGeneral DentistryFinlandResponse rate (survey)MotivationMedical educationta313Career ChoicePrestigeGender Identity030206 dentistryVariety (linguistics)language.human_languageCounselorsWorkforcelanguageWorkforce planningFemalePsychologyEuropean Journal of Dental Education
researchProduct

The effect of vibration therapy on neck myofascial trigger points: A randomized controlled pilot study

2020

[EN] Background: The purpose of this study was to evaluate the effect of low-frequency self-administered vibration therapy into myofascial trigger points in the upper trapezius and levator scapulae on patients with chronic non-specific neck pain. Methods: Twenty-eight patients with chronic non-specific neck pain were randomly assigned into a vibration group, receiving 10 self-applied sessions of vibration therapy in the upper trapezius and levator scapulae trigger points; or a control group, receiving no intervention. Self-reported neck pain and disability (Neck Disability Index) and pressure pain threshold were assessed at baseline and after the first, fifth and 10th treatment sessions. Fi…

AdultMaleUpper trapeziusmedicine.medical_specialtyPressure painmedicine.medical_treatmentESTADISTICA E INVESTIGACION OPERATIVABiophysicsPilot ProjectsVibration03 medical and health sciences0302 clinical medicineNeck painThreshold of painmedicineHumansDisabled PersonsOrthopedics and Sports MedicineIn patientPROYECTOS DE INGENIERIAPhysical Therapy ModalitiesNeck painNeck PainRehabilitationTrigger pointsbusiness.industryRehabilitationTrigger Points030229 sport sciencesMiddle AgedTreatment periodTreatment OutcomePain thresholdPhysical therapyFemalemedicine.symptombusiness030217 neurology & neurosurgeryNeck Disability IndexClinical Biomechanics
researchProduct

EchoScopy in scanning abdominal diseases: initial clinical experience.

2014

Background and Aims: The introduction of a new type of small handheld ultrasound device brings greater portability and affordability. The basic ultrasound approach with these handheld devices has been defined by European Federation of Societies of Ultrasound in Medicine and Biology (EFSUMB) as “EchoScopy”. The current study aimed to assess the image quality, indications and limitations of a portable pocket “EchoScope” compared with a high-end ultrasound system in abdominal diseases. Methods: 231 consecutive patients were included in this study. Physician A performed ultrasound examinations with a high-end ultrasound system (HEUS), then physician B performed the same ultrasound examination u…

AdultMaleUrologic Diseasesmedicine.medical_specialtyAdolescentImage qualityDigestive System DiseasesPilot ProjectsEndocrine System DiseasesSensitivity and SpecificityLesionYoung AdultVascularityAscitesAbdomenMedicineHumansUltrasonography Doppler ColorProspective cohort studyChildPathologicalHydronephrosisAgedAged 80 and overMiniaturizationbusiness.industryUltrasoundGastroenterologyReproducibility of ResultsEquipment DesignMiddle Agedmedicine.diseaseEquipment Failure AnalysisCardiovascular DiseasesFemaleRadiologymedicine.symptombusinessZeitschrift fur Gastroenterologie
researchProduct

LOW-DOSE INTERLEUKIN-2 INDUCES SYSTEMIC IMMUNE RESPONSES AGAINST HBsAg IN IMMUNODEFICIENT NON-RESPONDERS TO HEPATITIS B VACCINATION

1989

Abstract A metabolic monocyte defect appears to correlate with non-responsiveness to hepatitis B vaccine in many patients on haemodialysis. This defect prevents production of interleukin-2 during T-cell activation after antigen contact. Receptors for interleukin-2 are, however, expressed in greater numbers than in healthy subjects or uraemic responders to hepatitis B vaccination. In this study, ten uraemic patients, previous non-responders to vaccination against hepatitis B, were revaccinated with the same vaccine combined with one intramuscular injection (2·5 × 10 5 U) of natural human interleukin-2. Systemic production of antibodies against hepatitis B surface antigen was initiated in tho…

AdultMaleViral Hepatitis VaccinesInterleukin 2HBsAgHepatitis B vaccinePilot ProjectsImmunoenzyme TechniquesImmune systemAntigenmedicineHumansHepatitis B VaccinesAgedUremiaHepatitis B Surface Antigensbiologybusiness.industryImmunologic Deficiency SyndromesReceptors Interleukin-2General MedicineMiddle AgedHepatitis Bmedicine.diseaseVirologyVaccinationAntibody FormationImmunologybiology.proteinInterleukin-2FemaleAntibodybusinessmedicine.drugThe Lancet
researchProduct

Vitamin B1 Intake in Multiple Sclerosis Patients and its Impact on Depression Presence: A Pilot Study

2020

Vitamin B1, or thiamine, is one of the most relevant vitamins in obtaining energy for the nervous system. Thiamine deficiency or lack of activity causes neurological manifestations, especially symptoms of depression, intrinsic to multiple sclerosis (MS) and related to its pathogenesis. On this basis, the aim of this study was to determine the possible relationship between the nutritional habits of patients with MS and the presence of depression. Therefore, a cross-sectional and observational descriptive study was conducted. An analysis of dietary habits and vitamin B1 consumption in a Spanish population of 51 MS patients was performed by recording the frequency of food consumption. Results …

AdultMaleVitaminvitamin B1Food HandlingHealth BehaviorNutritional StatusPhysiologyPilot Projectslcsh:TX341-641Significant negative correlationmultiple sclerosisArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDietary CarbohydratesmedicineHumansThiamine030212 general & internal medicineEating habitsDepression (differential diagnoses)Nutrition and Dieteticsbusiness.industryMultiple sclerosisMiddle Agedmedicine.diseaseDietSpanish populationCross-Sectional StudieschemistryDietary SupplementsdepressionFast FoodsFemaleThiamineObservational studySnacksbusinesslcsh:Nutrition. Foods and food supply030217 neurology & neurosurgeryFood Science
researchProduct

Factorial Structure of Web-Credibility in a population of Italian Internet Users. A pilot study

2009

Recent studies by Fogg and his colleagues have defined a new psychological construct called Web credibility. It describes the principal dimensions which lead people to believe (or not) online information. In this framework, the factorial structure of Web credibility was explored in a sample of 152 Italian students of psychology who were Internet users, using a questionnaire. A consistent four-factorial structure emphasized crucial aspects of Web credibility, namely, Inaccuracy, Efficiency, Social Validation, and Commercial Features. Such results seem in line with Fogg's theoretical model; however, further research is required to identify dimensions of this construct.

AdultMaleWeb-credibilitySettore M-PSI/01 - Psicologia GeneraleFactorialWeb credibilityPopulationPilot ProjectsSample (statistics)EfficiencyModels PsychologicalTrustcognitive assessementWorld Wide WebUser-Computer InterfaceSurveys and QuestionnairesHumansStudentseducationGeneral PsychologyStructure (mathematical logic)Interneteducation.field_of_studyAttitude to ComputersPrincipal (computer security)Equipment DesignTranslatingItalyFemaleInternet usersFactor Analysis StatisticalConstruct (philosophy)PsychologySocial psychologyfactorial study
researchProduct

Postural stability in subjects with whiplash injury symptoms: results of a pilot study

2014

Posturographic tests can be used to assess and confirm the body's imbalance in subjects with whiplash injury. Further studies with larger cohorts are necessary to confirm this pilot study.To verify through a posturographic exam the qualitative and quantitative alterations of postural stability in subjects with previous cervical trauma in comparison with healthy subjects.A total of 42 subjects were analysed for the study; 22 as the control group (NM) and 20 (WM) with a positive anamnesis of whiplash injury from 3 to 12 month from diagnosis through a force platform. Centre of pressure (CoP) movements of the two groups with their eyes open and closed were recorded.During the closed eye test, t…

AdultMaleforce platformmedicine.medical_specialtyPoison controlPilot ProjectsYoung AdultVertigoInjury preventionmedicineHumansForce platformPostural BalanceAnamnesisbiologybusiness.industryPosturographycentre of pressureposturographyGeneral Medicinebiology.organism_classificationWhiplash injuryOtorhinolaryngologyCase-Control StudiesPostural stabilityVertigoPhysical therapybusinessWhipple DiseaseActa Oto-Laryngologica
researchProduct

Changes in accommodative responses with multifocal contact lenses: a pilot study.

2011

Our aim was to evaluate induced changes in pupil and accommodative response for different accommodative stimuli with three different multifocal contact lenses (CLs). Accommodative and pupil responses with three aspheric multifocal CLs of simultaneous focus center near (PureVision Low Add, PureVision High Add and Focus Progressives) for two accommodative stimuli of -2.5 and -4.00 D were recorded in 10 young subjects. Accommodative response, peak velocity, and time constant of accommodation and pupil constriction were assessed. The measurements were evaluated in all the participants with distance-single vision CLs and with the three multifocal CLs. The monocular measurements were performed in…

AdultMalemedicine.medical_specialtyAccommodative responsegenetic structuresContact LensesVisual AcuityPilot ProjectsRefraction OcularPupillaw.inventionOpticsCLs upper limitslawOphthalmologymedicineHumansMathematicsMonocularCross-Over Studiesbusiness.industryAccommodation OcularPupilPresbyopiaEquipment Designmedicine.diseaseRefractive Errorseye diseasesLens (optics)OphthalmologyTreatment OutcomePeak velocityOftalmologíaFemalebusinessAccommodationOptometryFollow-Up StudiesOptometry and vision science : official publication of the American Academy of Optometry
researchProduct