Search results for "Pirati"

Sleep apnoea and metabolic dysfunction.

2013

Obstructive sleep apnoea (OSA) is a highly prevalent condition often associated with central obesity. In the past few years, several studies have analysed the potential independent contribution of OSA to the pathogenesis of metabolic abnormalities, including type 2 diabetes, the metabolic syndrome and non-alcoholic fatty liver disease. New perspectives in OSA patient care have been opened by the promotion of lifestyle interventions, such as diet and exercise programmes that could improve both OSA and the metabolic profile. The rich clinical literature on this subject, together with the growing amount of data on pathophysiological mechanisms provided by animal studies using the chronic inter…

Dynamic determination of oxygenation and lung compliance in murine pneumonectomy.

2011

Thoracic surgical procedures in mice have been applied to a wide range of investigations, but little is known about the murine physiologic response to pulmonary surgery. Using continuous arterial oximetry monitoring and the FlexiVent murine ventilator, the authors investigated the effect of anesthesia and pneumonectomy on mouse oxygen saturation and lung mechanics. Sedation resulted in a dose-dependent decline of oxygen saturation that ranged from 55% to 82%. Oxygen saturation was restored by mechanical ventilation with increased rate and tidal volumes. In the mouse strain studied, optimal ventilatory rates were a rate of 200/minute and a tidal volume of 10 mL/kg. Sustained inflation pressu…

Renin-angiotensin system inhibitors effect before and during hospitalization in COVID-19 outcomes: Final analysis of the international HOPE COVID-19 …

2021

Background The use of Renin-Angiotensin system inhibitors (RASi) in patients with coronavirus disease 2019 (COVID-19) has been questioned because both share a target receptor site. Methods HOPE-COVID-19 (NCT04334291) is an international investigator-initiated registry. Patients are eligible when discharged after an in-hospital stay with COVID-19, dead or alive. Here, we analyze the impact of previous and continued in-hospital treatment with RASi in all-cause mortality and the development of in-stay complications. Results We included 6503 patients, over 18 years, from Spain and Italy with data on their RASi status. Of those, 36.8% were receiving any RASi before admission. RASi patients were …

A simple algorithm to estimate evapotranspiration from DAIS data: Application to the DAISEX campaigns

2005

DOI:10.1016/j.jhydrol.2005.03.027; The knowledge of evapotranspiration is of great interest in many applications such as assessing irrigation water use. In this paper, a methodology is presented to estimate evapotranspiration using the surface energy balance model S-SEBI (Simplified Surface Energy Balance Index) and the evaporative fraction. The method is applicable under the assumptions of constant atmospheric conditions and sufficient wet and dry pixels over the image. The model uses remotely sensed parameters such as albedo, MSAVI (Modified Soil Adjusted Vegetation Index) and surface temperature and emissivity images. The methodology has been applied over the Barrax test site, located in…

Thermal remote sensing in the framework of the SEN2FLEX project: field measurements, airborne data and applications

2008

A description of thermal radiometric field measurements carried out in the framework of the European project SENtinel-2 and Fluorescence Experiment (SEN2FLEX) is presented. The field campaign was developed in the region of Barrax (Spain) during June and July 2005. The purpose of the thermal measurements was to retrieve biogeophysical parameters such as land surface emissivity (LSE) and temperature (LST) to validate airborne-based methodologies and to characterize different surfaces. Thermal measurements were carried out using two multiband field radiometers and several broadband field radiometers, pointing at different targets. High-resolution images acquired with the Airborne Hyperspectral…

Oxygen regulated gene expression in facultatively anaerobic bacteria

1994

In facultatively anaerobic bacteria such as Escherichia coli, oxygen and other electron acceptors fundamentally influence catabolic and anabolic pathways. E. coli is able to grow aerobically by respiration and in the absence of O2 by anaerobic respiration with nitrate, nitrite, fumarate, dimethylsulfoxide and trimethylamine N-oxide as acceptors or by fermentation. The expression of the various catabolic pathways occurs according to a hierarchy with 3 or 4 levels. Aerobic respiration at the highest level is followed by nitrate respiration (level 2), anaerobic respiration with the other acceptors (level 3) and fermentation. In other bacteria, different regulatory cascades with other underlyin…

Previously undiagnosed Reinke edema as a cause of immediate postextubation inspiratory stridor

2015

Reinke edema (RE) is an uncommon lesion of the vocal folds and a potential cause of complications during airway management. We report the case of a woman with previously unknown RE admitted to the intensive care unit who experienced postextubation inspiratory stridor immediately after separation from mechanical ventilation. RE should be considered among causes of postextubation stridor.

Assessing opportunities for water savings in large-scale pressurized irrigation systems using actual evapotranspiration retrieved by surface energy b…

Remote sensing allows the observation of large land stretches and the acquisition of worthwhile information that can be used efficaciously in agro-hydrologic systems. Satellite imagery associated to computational models provide a reliable resource in estimating evapotranspiration (ET) fluxes based on surface energy balance. On irrigated crops, quantifying the spatial distribution of actual ET enables a broad range of applications such as irrigation management, monitoring water distribution, assessing crop water status and irrigation system performance. The general objective of the research was to propose a methodology to estimate ET by using Landsat Thematic Mapper (TM) images and surface e…

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): study protocol for a randomized controlled trial.

2012

Abstract Background Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with …

NADH dehydrogenase deficiency results in low respiration rate and improved aerobic growth of Zymomonas mobilis.

2008

The respiratory chain of the ethanol-producing bacterium Zymomonas mobilis is able to oxidize both species of nicotinamide cofactors, NADH and NADPH. A mutant strain with a chloramphenicol-resistance determinant inserted in ndh (encoding an NADH : CoQ oxidoreductase of type II) lacked the membrane NADH and NADPH oxidase activities, while its respiratory d-lactate oxidase activity was increased. Cells of the mutant strain showed a very low respiration rate with glucose and no respiration with ethanol. The aerobic growth rate of the mutant was elevated; exponential growth persisted longer, resulting in higher biomass densities. For the parent strain a similar effect of aerobic growth stimulat…