Search results for "Planet"
showing 10 items of 5662 documents
Philosophy and language in young Nietzsche
2015
Resumo:O objetivo deste estudo é a exposição da filosofia da linguagem que Nietzsche apresenta em suas primeiras obras, sobretudo em seu decisivo escrito póstumo de 1873. São considerados três aspectos da trajetória de Nietzsche. Seu interesse pela linguagem poética e musical, desde a juventude; sua formação em filologia clássica; suas investigações filosóficas sobre o tema. Pretendemos mostrar como, nesse período, se parte de uma concepção metafísica para uma visão mais linguística. Nietzsche parte do fundamento metafísico para uma versão da linguagem como relação de signos e símbolos. Abstract:The purpose of this study is the explanation of the philosophy of language that Nietzsche presen…
Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge…
2021
Interstitial pneumonia is a life-threatening clinical manifestation of cytomegalovirus infection in recipients of hematopoietic cell transplantation (HCT). The mouse model of experimental HCT and infection with murine cytomegalovirus revealed that reconstitution of virus-specific CD8+ T cells is critical for resolving productive lung infection. CD8+ T-cell infiltrates persisted in the lungs after the establishment of latent infection. A subset defined by the phenotype KLRG1+CD62L− expanded over time, a phenomenon known as memory inflation (MI). Here we studied the localization of these inflationary T effector-memory cells (iTEM) by comparing their frequencies in the intravascular and transm…
Determining the infrared radiative effects of Saharan dust: a radiative transfer modelling study based on vertically resolved measurements at Lampedu…
2018
Detailed measurements of radiation, atmospheric and aerosol properties were carried out in summer 2013 during the Aerosol Direct Radiative Impact on the regional climate in the MEDiterranean region (ADRIMED) campaign in the framework of the Chemistry-Aerosol Mediterranean Experiment (ChArMEx) experiment. This study focusses on the characterization of infrared (IR) optical properties and direct radiative effects of mineral dust, based on three vertical profiles of atmospheric and aerosol properties and IR broadband and narrowband radiation from airborne measurements, made in conjunction with radiosonde and ground-based observations at Lampedusa, in the central Mediterranean. Satellite IR spe…
Fabry Disease, a Complex Pathology Not Easy to Diagnose
2015
Fabry disease is a multisystemic lysosomal storage disorder, inherited in an X-linked manner. It is a defect of metabolism of the glycosphingolipids, due to the reduction or absence of the activity of lysosomal enzyme α-galactosidase A. This reduction of activity causes the storage of globotriaosylceramide and derivatives in the lysosomes, triggering a cascade of cellular events, mainly in vascular endothelium. These events are the responsible for the systemic clinical manifestations and the renal, cardiac and cerebrovascular complications, or a combination of them. The symptomatology can lead to the premature death of patient between the fourth or fifth decade of life. The first symptoms c…
Vulnerability to climate change and adaptation strategies of local communities in Malawi: experiences of women fish-processing groups in the Lake Chi…
2016
Abstract. In recent years, research on climate change and human security has received much attention among policy makers and academia alike. Communities in the Global South that rely on an intact resource base and struggle with poverty, existing inequalities and historical injustices will especially be affected by predicted changes in temperature and precipitation. The objective of this article is to better understand under what conditions local communities can adapt to anticipated impacts of climate change. The empirical part of the paper answers the question as to what extent local women engaged in fish processing in the Chilwa Basin in Malawi have experienced climate change and how they …
The magnesium isotope record of cave carbonate archives
2012
Here we explore the potential of magnesium (&delta;<sup>26</sup>Mg) isotope time-series data as continental climate proxies in speleothem calcite archives. For this purpose, a total of six Pleistocene and Holocene stalagmites from caves in Germany, Morocco and Peru and two flowstones from a cave in Austria were investigated. These caves represent the semi-arid to arid (Morocco), the warm-temperate (Germany), the equatorial-humid (Peru) and the cold-humid (Austria) climate zones. Changes in the calcite magnesium isotope signature with time are compared against carbon and oxygen isotope records from these speleothems. Similar to other proxies, the non-trivial interaction of a …
Monitoring and prediction in early warning systems for rapid mass movements
2015
Rapid mass movements (RMM) pose a substantial risk to people and infrastructure. Reliable and cost-efficient measures have to be taken to reduce this risk. One of these measures includes establishing and advancing the state of practice in the application of early warning systems (EWSs). EWSs have been developed during the past decades and are rapidly increasing. In this paper, we focus on the technical part of EWSs, i.e., the prediction and timely recognition of imminent hazards, as well as on monitoring slopes at risk and released mass movements. Recent innovations in assessing spatial precipitation, monitoring and precursors of the triggering and deformation of RMM offer new opportunities…
The reconstruction of easterly wind directions for the Eifel region (Central Europe) during the period 40.3–12.9 ka BP
2010
Abstract. A high resolution continuous reconstruction of last glacial wind directions is based on provenance analysis of eolian sediments in a sediment core from the Dehner dry Maar in the Eifel region (Germany). This Maar is suitable to archive easterly wind directions due to its location west of the Devonian carbonate basins of the Eifel-North-South-Zone. Thus, eolian sediments with high clastic carbonate content can be interpreted as an east wind signal. The detection of such east wind sediments is applied by a new module of the RADIUS grain size analyze technique. The investigated time period from 40.3–12.9 ka BP can be subclassified in three units: The first unit covers the periods of …
Blue intensity and density from northern Fennoscandian tree rings, exploring the potential to improve summer temperature reconstructions with earlywo…
2014
Abstract. Here we explore two new tree-ring parameters, derived from measurements of wood density and blue intensity (BI). The new proxies show an increase in the interannual summer temperature signal compared to established proxies, and present the potential to improve long-term performance. At high latitudes, where tree growth is mainly limited by low temperatures, radiodensitometric measurements of wood density, specifically maximum latewood density (MXD), provides a temperature proxy that is superior to that of tree-ring widths. The high cost of developing MXD has led to experimentation with a less expensive method using optical flatbed scanners to produce a new proxy, herein referred t…
Temperature variability in the Iberian Range since 1602 inferred from tree-ring records
2017
Abstract. Tree rings are an important proxy to understand the natural drivers of climate variability in the Mediterranean Basin and hence to improve future climate scenarios in a vulnerable region. Here, we compile 316 tree-ring width series from 11 conifer sites in the western Iberian Range. We apply a new standardization method based on the trunk basal area instead of the tree cambial age to develop a regional chronology which preserves high- to low-frequency variability. A new reconstruction for the 1602–2012 period correlates at −0.78 with observational September temperatures with a cumulative mean of the 21 previous months over the 1945–2012 calibration period. The new IR2Tmax reconstr…