Search results for "Plant Stem"

showing 10 items of 40 documents

Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells.

2012

Abstract Objective Mango (Mangifera indica L.) stem bark extract (MSBE) is a natural product with biological properties and mangiferin is the major component. This paper reported the evaluation of the protective effects of MSBE and mangiferin against the toxicity induced in HepG2 cells by tert-butyl hydroperoxide or amiodarone. Method Nuclear morphology, cell viability, intracellular calcium concentration and reactive oxygen species (ROS) production were measured by using a high-content screening multiparametric assay. Key findings MSBE and mangiferin produced no toxicity below 500 mg/ml doses. A marked recovery in cell viability, which was reduced by the toxicants, was observed in cells pr…

Cell SurvivalXanthonesPharmaceutical ScienceAmiodaronePharmacologychemistry.chemical_compoundtert-ButylhydroperoxidemedicineHumansMangiferaViability assayATP Binding Cassette Transporter Subfamily B Member 1MangiferinP-glycoproteinPharmacologychemistry.chemical_classificationReactive oxygen speciesMangiferabiologyDose-Response Relationship DrugPlant StemsPlant ExtractsHep G2 Cellsmedicine.diseaseCytoprotectionMitochondrial toxicityBiochemistrychemistryToxicitybiology.proteinPlant BarkCalciumReactive Oxygen SpeciesThe Journal of pharmacy and pharmacology
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Labdane Diterpenes from Stachys plumosa

2000

Three new labdane diterpenoids were isolated from the aerial parts of Stachys plumosa. The first two (1, 2) were the dextrorotatory enantiomers of the known 6-deoxyandalusol and 13-epijabugodiol. Structures were determined using NMR and MS techniques. The absolute stereochemistry of the third compound (3) was not experimentally proved.

Chromatography GasMagnetic Resonance SpectroscopyOptical RotationStereochemistryPharmaceutical ScienceGas Chromatography-Mass SpectrometryAnalytical ChemistryDextrorotatoryLabdanechemistry.chemical_compoundBalkan peninsulaDrug DiscoveryOrganic chemistryPharmacologyLamiaceaePlant StemsChemistryOrganic ChemistryAbsolute configurationStachys plumosaTerpenoidPlant LeavesItalyComplementary and alternative medicineChromatography GelMolecular MedicineSpectrophotometry UltravioletEpimerDiterpenesDiterpeneJournal of Natural Products
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Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from …

2016

From the twigs and stems of the Chinese liana Ancistrocladus tectorius (Ancistrocladaceae), two new 5,8'-coupled naphthylisoquinolines, ancistectorine D (5) and its 6-O-demethyl derivative 6, were isolated, along with two new 7,1'-linked alkaloids, 6-O-methylancistectorine B1 (7) and ancistectorine B2 (8). Two further compounds, ancistroealaine A (4) and 6-O-demethyl-8-O-methyl-7-epi-ancistrobrevine D (10), already known from related Asian and African Ancistrocladus species, were discovered for the first time in A. tectorius. The structure elucidation was achieved by spectroscopic analysis including HRESIMS, 1D and 2D NMR, and by chemical (oxidative degradation) and chiroptical (circular di…

Circular dichroismStereochemistrymedicine.drug_classTrypanosoma cruziAntiprotozoal AgentsLeishmania donovaniNaphtholsBiology01 natural sciencesMagnoliopsidaAlkaloidsCell Line TumorDrug DiscoverymedicineHumansTrypanosoma cruziPharmacologyMolecular StructurePlant Stems010405 organic chemistryAlkaloidGeneral MedicineIsoquinolinesbiology.organism_classificationAntineoplastic Agents PhytogenicDrug Resistance Multiple0104 chemical sciences010404 medicinal & biomolecular chemistryLianaDrug Resistance NeoplasmAntiprotozoalAncistrocladaceaeTwo-dimensional nuclear magnetic resonance spectroscopyLeishmania donovaniFitoterapia
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Composting rice straw with sewage sludge and compost effects on the soil-plant system.

2008

Composting organic residue is an interesting alternative to recycling waste as the compost obtained may be used as organic fertilizer. This study aims to assess the composting process of rice straw and sewage sludge on a pilot-scale, to evaluate both the quality of the composts obtained and the effects of applying such compost on soil properties and plant development in pot experiments. Two piles, with shredded and non-shredded rice straw, were composted as static piles with passive aeration. Throughout the composting process, a number of parameters were determined, e.g. colour, temperature, moisture, pH, electrical conductivity, organic matter, C/N ratio, humification index, cation exchang…

Conservation of Natural ResourcesEnvironmental EngineeringHealth Toxicology and Mutagenesisengineering.materialSoilWaste ManagementCation-exchange capacityEnvironmental ChemistryPlant StemsSewageCompostPublic Health Environmental and Occupational HealthSoil classificationAgricultureOryzaGeneral MedicineGeneral ChemistryStrawPollutionHumusSoil conditionerAgronomyengineeringEnvironmental scienceHordeum vulgareOrganic fertilizerChemosphere
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In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus alba L. Leaves, Stems and Fruits

2012

In this study, the aqueous and ethanolic extracts (leaves, stems and fruits) from Morus alba L., a traditional Chinese medicine, were evaluated for their antioxidant and antimicrobial properties. Ethanolic extracts showed higher contents of both total phenolics and flavonoids than aqueous extracts. The total phenolic content was in the order of: leaf extracts > fruit extracts > stem extracts, whereas the total flavonoids was: leaf extracts > stem extracts > fruit extracts. Using DPPH assays, the concentrations providing 50% inhibition (IC50) values of aqueous extracts from leaves, stems and fruits were 7.11 ± 1.45 mg/ml, 86.78 ± 3.21 mg/ml and 14.38 ± 2.83 mg/ml, respectively, …

FlavonoidsAntioxidantBacteriaPlant StemsTraditional medicinePlant ExtractsDPPHFruit extractsmedicine.medical_treatmentfood and beveragesGeneral MedicineAntimicrobialAntioxidantsIn vitroPlant Leaveschemistry.chemical_compoundAnti-Infective AgentsPhenolsComplementary and alternative medicinechemistryFruitCandida albicansmedicineMorusPhenolsThe American Journal of Chinese Medicine
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Traditional medicine as a source of new therapeutic agents against psoriasis.

2000

In the frame of traditional medicine, the use in the treatment of psoriasis of some plants typical of the flora of Sicily is reported. A preliminary search on some plants used for the treatment of psoriasis in Asia, South America and Africa is also reported.

Floramedicine.medical_specialtyMEDLINEAlternative medicinelaw.inventionlawPsoriasisDrug DiscoverymedicineHumansPsoriasisMedicinal plantsSicilyPharmacologyPlants MedicinalTraditional medicinePlant Stemsbusiness.industryPlant Extractsfungifood and beveragesRhagadiolus stellatusGeneral Medicinemedicine.diseasePlant LeavesMedicine TraditionalbusinessPhytotherapyPhytotherapyFitoterapia
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Chemical composition of the essential oil from the aerial parts of Ononis reclinata L. (Fabaceae) grown wild in Sicily

2016

In the present study, the chemical composition of the essential oil from aerial parts of Ononis reclinata L., a species not previously investigated, collected in Sicily was evaluated by GC and Gas chromatography-Mass spectrometry. The main components of O. reclinata were menthone (43.6%), isopimpinellin (38.4%) and pulegone (11.2%). The comparison with other studied oils of genus Ononis showed a peculiar and characteristic profile.

IsopimpinellinChromatography GasmenthoneFlowersPlant ScienceBiology01 natural sciencesBiochemistryPlant StemGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundGenuslawOnonisBotanyOils VolatileOnoniSicilyChemical compositionEssential oilpulegoneOnonis reclinataPlant Stems010405 organic chemistryOrganic ChemistryFabaceaeFabaceaeisopimpinellinPlant Components Aerialbiology.organism_classificationMenthone0104 chemical sciencesPlant Leavesvolatile component010404 medicinal & biomolecular chemistrychemistryChromatography GaFlowerOnonisPlant LeavePulegoneNatural Product Research
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The stem rust resistance gene Rpg5 encodes a protein with nucleotide-binding-site, leucine-rich, and protein kinase domains

2008

We isolated the barley stem rust resistance genes Rpg5 and rpg4 by map-based cloning. These genes are colocalized on a 70-kb genomic region that was delimited by recombination. The Rpg5 gene consists of an unusual structure encoding three typical plant disease resistance protein domains: nucleotide-binding site, leucine-rich repeat, and serine threonine protein kinase. The predicted RPG5 protein has two putative transmembrane sites possibly involved in membrane binding. The gene is expressed at low but detectable levels. Posttranscriptional gene silencing using VIGS resulted in a compatible reaction with a normally incompatible stem rust pathogen. Allele sequencing also validated the candi…

LRP1BSerine threonine protein kinaseBiologyGenes PlantSYT1LeucineHSPA2SNAP23Gene SilencingCloning MolecularPlant DiseasesPlant ProteinsTAF15HSPA9GeneticsBinding SitesMultidisciplinaryPlant StemsNucleotidesFungifood and beveragesHordeumBiological SciencesPhysical Chromosome MappingProtein Structure TertiaryGPS2Protein KinasesProceedings of the National Academy of Sciences
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New prenylhydroquinone glycosides from Phagnalon rupestre.

2001

Three new hydroquinone glycosides were isolated from the MeOH extract of the aerial parts of Phagnalon rupestre. Their structures were elucidated as 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3',3'-dimethylallyl)benzene (1), 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3'-hydroxymethyl-3'-methylallyl)benzene (2), and 1-O-(4' '-O-caffeoyl)-beta-glucopyranosyl-1,4-dihydroxy-2-(3',3'-dimethylallyl)benzene (3) by spectroscopic methods.

Magnetic Resonance SpectroscopySpectrophotometry InfraredStereochemistryPharmaceutical ScienceAsteraceaeAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryPhenolsGlycosidesBenzenePharmacologychemistry.chemical_classificationChromatographyPlants MedicinalHydroquinoneMolecular StructurePlant StemsOrganic ChemistryGlycosidePhagnalon rupestreHydroquinonesComplementary and alternative medicinechemistryAldoseSpainMolecular MedicineSpectrophotometry UltravioletJournal of natural products
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Oxidative burst inhibitory and cytotoxic amides and lignans from the stem bark of Fagara heitzii (Rutaceae)

2009

Two amides, heitziamide A and heitziamide B and two phenylethanoids, heitziethanoid A and heitziethanoid B together with thirteen known compounds were isolated from F. heitzii (Letouzey). The structures of all compounds were established by spectroscopic analysis. Nine compounds were evaluated for oxidative burst inhibitory activity in a chemoluminescence assay and for cytotoxicity against PC-3 prostate cancer cells. All compounds exhibited a clear suppressive effect on phagocytosis response upon activation with serum opsonized zymosan at the range of IC50 = 2.0-6.5 mu M, but no cytotoxic effect was observed (IC50 > 100 mu M). (C) 2009 Elsevier Ltd. All rights reserved.

MaleCytotoxicityChemical structurePhagocytosisPlant ScienceHorticultureHeterocyclic Compounds 2-RingBiochemistryAntioxidantsLignansInhibitory Concentration 50chemistry.chemical_compoundPhagocytosisCell Line TumorHumansImmunologic FactorsCytotoxic T cellFagara heitziiCytotoxicityRutaceaeMolecular BiologyRespiratory BurstLignanPlant StemsPlant ExtractsZymosanZymosanProstatic NeoplasmsBiological activityGeneral MedicineAntineoplastic Agents PhytogenicAmidesOxidative burstinhibitionRespiratory burstchemistryBiochemistryPlant BarkPhenylethanoidsPhytochemistry
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