Search results for "Podium"
showing 10 items of 41 documents
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
2009
Profilins are key factors for dynamic rearrangements of the actin cytoskeleton. However, the functions of profilins in differentiated mammalian cells are uncertain because profilin deficiency is early embryonic lethal for higher eukaryotes. To examine profilin function in chondrocytes, we disrupted the profilin 1 gene in cartilage (Col2pfn1). Homozygous Col2pfn1 mice develop progressive chondrodysplasia caused by disorganization of the growth plate and defective chondrocyte cytokinesis, indicated by the appearance of binucleated cells. Surprisingly, Col2pfn1 chondrocytes assemble and contract actomyosin rings normally during cell division; however, they display defects during late cytokines…
Numerical Treatment of the Filament-Based Lamellipodium Model (FBLM)
2017
We describe in this work the numerical treatment of the Filament-Based Lamellipodium Model (FBLM). This model is a two-phase two-dimensional continuum model, describing the dynamics of two interacting families of locally parallel F-actin filaments. It includes, among others, the bending stiffness of the filaments, adhesion to the substrate, and the cross-links connecting the two families. The numerical method proposed is a Finite Element Method (FEM) developed specifically for the needs of this problem. It is comprised of composite Lagrange–Hermite two-dimensional elements defined over a two-dimensional space. We present some elements of the FEM and emphasize in the numerical treatment of t…
Characterization and conservation of Clinopodium raimondoi Spadaro, A.S. Faqi & Mazzola germplasm in the Parco della Favorita of Palermo city (Si…
2017
In urban areas, the parks represent an important source of plant biodiversity. The Parco della Favorita is the largest green area in Palermo city (Sicily, Italy). Clinopodium raimondoi Spadaro, A.S. Faqi & Mazzola is an aromatic plant species which has a range of uses in Sicilian traditional culture. The essential oil of this species is rich in terpene components and its aroma is similar to that of mint. The aim of this study was to enhance the germplasm of C. raimondoi in the Parco della Favorita. A collection-field was set up within the park. The main biometric and productive parameters of the species were determined and gas chromatographic analyses were carried out to determine the quali…
Desarrollo de formulaciones alimentarias basadas en Chenopodium quinoa y Salvia hispanica L. con función preventivo/terapéutica de trastornos en el m…
2021
El incremento de enfermedades relacionadas con alteraciones en la homeostasis de la glucosa (i.e., obesidad, diabetes, glucogenosis), ha generado un continuo interés en el consumo de la quinoa (Chenopodium quinoa) y la chía (Salvia hispanica L.). Por ello, se ha estudiado en un primer objetivo el almidón de quinoa comparado con otros almidones comerciales (patata, arroz, trigo, maíz), determinando sus propiedades térmicas y de pasta y el efecto del tratamiento hidrotérmico en sus cinéticas de liberación de glucosa, así como evaluar el efecto de añadir harina de chía desgrasada (H_Ch) en los flujos de glucosa y en la respuesta metabólica en células HepG2. Como segundo objetivo, se ha estudia…
Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer population from Spain
2012
[EN] The essential oil composition of Cistus ladanifer grown in central Spain was analysed by gas chromatography and gas chromatography/mass spectrometry, revealing it to be rich in oxygenated compounds, with trans-pinocarveol (20.00%), bornyl acetate (7.03%) and terpinen-4-ol (6.37%) as the main monoterpene compounds. Viridiflorol (13.59%) and ledol (4.36%) were the main constituents of the oxygenated sesquiterpene fraction. Large amounts of-pinene (4.70%) were found in the hydrocarbonated fractions. To study its possible use as a natural herbicide, the oil was tested invitro against Amaranthus hybridus, Portulaca oleracea, Chenopodium album, Conyza canadensis and Parietaria judaica, compl…
Clinopodium raimondoi (Lamiaceae), a new species from Sicily
2015
On the basis of the taxonomic study of the collections made by F. M. Raimondo, kept in PAL, a new species of Clinopodium is described. The new taxon, named Clinopodium raimondoi, occurs in N-W coast of Sicily on limestone substrata, in steppe communities dominated by Hyparrhenia hirta. The main distinctive characteristics of C. raimondoi, with respect to other taxa known from Europe and other Mediterranean countries, are the large size, the opposite and decussate branches, and the clearly woody at base stems of mature plants as well. Relationships of the new taxon with the Mediterranean ones in the C. nepeta group are also discussed.
Popular uses of wild plant species for medicinal purposes in the Nebrodi Regional Park (North-Eastern Sicily, Italy)
2014
Ethnopharmacological relevance: The area of the Nebrodi Regional Park (North-Eastern Sicily, Italy) has Q3 been quantitatively investigated in an ethnobotanical study for the first time. A total of 90 wild species are used for medicinal purposes and the uses of 5 species have not previously been reported in ethnobotanical studies in Italy (e.g., the use of Arisarum vulgare O. Targ. Tozz. for the treatment of rheumatic pains, the use of Silene vulgaris (Moench) Garcke for the treatment of liver diseases). Aim of the study: The aim of this paper was to understand to what extent current knowledge on the medicinal use of plants is still an element of the culture within the rural populations of …
Floristic and phytosociological features of the Brachypodium rupestre communities in Italy
2018
The pale green dense Tor-grass (Brachypodium rupestre) tufts are a quite distinctive aspect of the Italian grassland pattern of the colline and submontane belts. B. rupestre is used to be found in secondary grasslands both in natural environments and in some aspects of the post-coltural environments such as forest clearances, abandoned terraced and extensive pastures. In northern Italy (Alps, Prealps and northern Apennines) B. rupestre has only sporadically been considered in the grasslands syntaxonomic frameworks. On the contrary it occurs in those regarding the central Italy where several semi-natural and post-coltural grassland associations (e.g. Polygalo flavescentis-Brachypodietum, Gal…
The joint evolution of the Myxozoa and their alternate hosts: A cnidarian recipe for success and vast biodiversity
2018
The relationships between parasites and their hosts are intimate, dynamic and complex; the evolution of one is inevitably linked to the other. Despite multiple origins of parasitism in the Cnidaria, only parasites belonging to the Myxozoa are characterized by a complex life cycle, alternating between fish and invertebrate hosts, as well as by high species diversity. This inspired us to examine the history of adaptive radiations in myxozoans and their hosts by determining the degree of congruence between their phylogenies and by timing the emergence of myxozoan lineages in relation to their hosts. Recent genomic analyses suggested a common origin of Polypodium hydriforme, a cnidarian parasit…
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.
2007
Phosphatidylinositol 4,5-bisphosphate [PI(4,5) P 2 ], a phosphoinositide concentrated predominantly in the plasma membrane, binds endocytic clathrin adaptors, many of their accessory factors, and a variety of actin-regulatory proteins. Here we have used fluorescent fusion proteins and total internal reflection fluorescence microscopy to investigate the effect of acute PI(4,5) P 2 breakdown on the dynamics of endocytic clathrin-coated pit components and of the actin regulatory complex, Arp2/3. PI(4,5) P 2 breakdown was achieved by the inducible recruitment to the plasma membrane of an inositol 5-phosphatase module through the rapamycin/FRB/FKBP system or by treatment with ionomycin. PI(4,5)…