Search results for "Pome"

showing 10 items of 525 documents

Hyperuricemia, cardiovascular profile, and comorbidity in older men and women: The Pro.V.A. Study

2017

Hyperuricemia (HU) is growing worldwide and associates with several medical conditions in the elderly. However, data about older people and possible gender differences are sparse. The aim of this study was to compare HU prevalence rates and association with relevant medical disorders in elderly subjects of both sexes. Pro.V.A. is a survey of 3099 individuals aged 65+, focusing on chronic diseases and disability. Uric acid (UA) levels were dichotomized using 6.0 mg/dL (females) and 7.0 mg/dL (males), and multivariate logistic regression models were used to estimate odds ratios (ORs) between HU and single comorbidity. HU prevalence was 21.5% in females and 15.8% in males. HU was associated wi…

MaleAgingmedicine.medical_specialtyPrevalenceComorbidityHyperuricemia030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineInternal medicineEpidemiologymedicineOdds RatioPrevalenceHumansHyperuricemiaLife StyleAged030203 arthritis & rheumatologyAnthropometrybusiness.industryCase-control studyOdds ratioAnthropometrymedicine.diseaseComorbidityUric AcidLogistic ModelsItalyCardiovascular DiseasesCase-Control StudiesPhysical therapyFemalecardiovascular diseases comorbidity elderly gender hypertension hyperuricemiaGeriatrics and GerontologybusinessBody mass index
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The mini nutritional assessment is associated with the perception of dyspnoea in older subjects with advanced COPD

2008

MaleAgingmedicine.medical_specialtymedia_common.quotation_subjectComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioRisk AssessmentSeverity of Illness IndexStatistics NonparametricCohort StudiesPulmonary Disease Chronic ObstructiveAge DistributionPhysical medicine and rehabilitationSurveys and QuestionnairesPerceptionSeverity of illnessmedicineHumansSex DistributionAgedProbabilitymedia_commonCOPDAnthropometrybusiness.industryIncidenceIncidence (epidemiology)General MedicineMiddle AgedAnthropometryPrognosismedicine.diseaseSurvival AnalysisComorbidityNutrition DisordersDyspneaNutrition AssessmentPhysical therapyFemalePerceptionBasal MetabolismGeriatrics and GerontologyRisk assessmentbusinessCohort studyDyspnea/diagnosis/*epidemiology
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Segmental contribution to forces in vertical jump.

1978

Performance of a vertical jump was analyzed with respect to the contribution of the different body segments to the forces acting on the whole body center of gravity. Both cinematograph and force-platform techniques were employed. The data disclosed that the take-off velocity in vertical jumps was caused by the different components as follows: knee extension 56%, plantar flexion 22%, trunk extension 10%, arm swing 10%, and head swing 2%. However, the average take-off velocity of the total performance (3.03 m/s) was only 76% from the theoretical maximum calculated from the segmental analyses. Optimal timing of the segmental performances was calculated to increase this “efficiency” to 84%. Gre…

MaleAnthropometryPhysiologyMovementPhysical ExertionPublic Health Environmental and Occupational HealthGeometryGeneral MedicineEfficiencySwingTrunkPlantar flexionBiomechanical PhenomenaVertical jumpCenter of gravityArm swingPhysiology (medical)HumansOrthopedics and Sports MedicineForce platformWhole bodyMathematicsEuropean journal of applied physiology and occupational physiology
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The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control st…

2015

Background Abdominal obesity (AO) is a common modifiable risk factor for certain non-communicable diseases associated with enhanced oxidative stress (OS). The objective of this work was to investigate whether the interaction between antioxidant vitamin intake and OS-related polymorphisms modulates gene-associated anthropometry in a Spanish population. Methods A total of 246 subjects with AO, and 492 age and gender matched non-AO subjects were included in the study. Anthropometric, biochemical, and OS parameters, and antioxidant dietary intake data were assessed using validated procedures. DNA from white blood cells was isolated and the genotype of seven polymorphisms from genes involved in …

MaleAntioxidantPolimorphismmedicine.medical_treatment:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Thioredoxins [Medical Subject Headings]Antioxidantes:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]AntioxidantsVitamin E intakeObesidad abdominalchemistry.chemical_compoundNutrigenomicsThioredoxinsPolymorphism (computer science):Anatomy::Cells::Blood Cells::Leukocytes [Medical Subject Headings]Risk FactorsGenotypeVitamin E:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyguanosine [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Micronutrients::Vitamins [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress [Medical Subject Headings]Abdominal obesityNutrigenómicaMedicine(all)AnthropometryAge FactorsGeneral MedicineAbdominal obesity:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity::Obesity Abdominal [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Waist circumferenceDietaFemale:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]medicine.symptomFactores de riesgoVitaminAdultmedicine.medical_specialtyGenotypeVitamina ECatechol-O-methyltransferaseBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Reporter [Medical Subject Headings]Catechol O-Methyltransferase:Chemicals and Drugs::Biological Factors::Pigments Biological::Carotenoids::Retinoids::Vitamin A [Medical Subject Headings]Polymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologySex FactorsInternal medicine:Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Antioxidants [Medical Subject Headings]medicinePerímetro abdominal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Waist Circumference [Medical Subject Headings]:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 2-Ring::Benzopyrans::Vitamin E [Medical Subject Headings]HumansObesityPolymorphismThioredoxinAgedCatechol-O-methyl transferaseBiochemistry Genetics and Molecular Biology(all)Vitamin EResearchCase-control studyGenes informadores:Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Nutrigenomics [Medical Subject Headings]DietOxidative StressEndocrinologychemistrySpainOxidative stressCase-Control Studies:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases::Catechol O-Methyltransferase [Medical Subject Headings]:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings]Genotipo
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Effect of a traditional Mediterranean diet on apolipoproteins B, A-I, and their ratio: a randomized, controlled trial.

2011

Objectives: Apolipoprotein (Apo)B, ApoA-I, and their ratio could predict coronary heart disease (CHD) risk more accurately than conventional lipid measurements. Our aim was to assess the effect of a traditional Mediterranean diet (TMD) on apolipoproteins. Methods: High-cardiovascular risk subjects (n=551, 308 women and 243 men), aged 55-80 years, were recruited into a large, multicenter, randomized, controlled, parallel-group, clinical trial (The PREDIMED Study) aimed at testing the efficacy of TMD on primary cardiovascular disease prevention. Participants assigned to a low-fat diet (control) (n=177), or TMDs (TMD. +. virgin olive oil (VOO), n=181 or TMD. +. nuts, n=193) received nutritiona…

MaleApolipoprotein BMediterranean dietCoronary DiseaseDiet MediterraneanDieta mediterràniaApolipoprotein B/A-I ratiolaw.inventionCohort StudiesRandomized controlled triallawVirgin olive oilMedicineNutsCardiometabolic riskAged 80 and overBioquímica y tecnologíabiologyAnthropometryMiddle AgedLipidsBiochemistry and technology0021-9150virgin olive oilApolipoproteïnesFemalelipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicineApolipoprotein BCohort studyRiskmedicine.medical_specialtyApolipoprotein B/A-IBioquímica i biotecnologiaInternal medicineMediterranean dietHumansPlant OilsOlive OilAgedApolipoproteins BApolipoprotein A-Ibusiness.industrynutritional and metabolic diseasesApolipoproteins bCardiometabolic riskClinical trialEndocrinologybiology.proteinbusinessOlive oil
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Mean power during 20 sec all-out test to predict 2000-m rowing ergometer performance in national level young rowers

2014

Aim. The aim of this study was to assess the relationship between mean power during 20-s all-out rowing ergometer test and 2000-m rowing ergometer performance, in 20 young male rowers (mean age 15.2 ± 1.3 years). Methods. Mean power during 20-s all-out test (W20), maximal oxygen uptake during incremental test (VO2max), and anthropometric values, were measured and correlated with the time to perform a 2000-m trial (t2000). Results. W20 showed the highest correlation with t2000 (r = -0.947, P < 0.0001). Stepwise multiple linear regression analysis showed that W20, VO2max, and fat-free mass, were the variables most correlated with t2000, accounting for 95.1% of the variance, and that 89.7% …

MaleAthletic performanceOxygen ConsumptionAdolescentAnthropometryErgometryResearch designHumansSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieRunningSportanaerobic power indoor rowing performance indoor rowing test
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Synergistic Antioncogenic Activity of Azacitidine and Curcumin in Myeloid Leukemia Cell Lines and Patient Samples.

2019

Background/aim Azacitidine (AZA) is a hypomethylating agent used in myeloid neoplasms, however, approximately half of patients show treatment failure or relapse. This in vitro study investigated the effect of the combination of AZA with the natural compound curcumin (CUR) in increasing its efficacy. Materials and methods We analyzed the effects of AZA plus CUR on proliferation, apoptosis, cell cycle and differentiation in myeloid leukemic cell lines (U-937, HL-60, K-562, and OCI-AML3) and bone marrow samples of patients. Results The results showed a synergy between AZA and CUR in all leukemic lines and in most leukemic samples, with a decrease in proliferation and an increase in apoptosis c…

MaleCancer ResearchMyeloidCurcuminAzacitidineAntineoplastic AgentsApoptosis03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCell Line TumormedicineHumansAgedAged 80 and overbusiness.industryCell CycleMyeloid leukemiaCell DifferentiationDrug SynergismGeneral MedicineCell cyclemedicine.anatomical_structureOncologychemistryHypomethylating agentApoptosisLeukemia Myeloid030220 oncology & carcinogenesisMyelodysplastic SyndromesCancer researchCurcuminAzacitidineFemaleBone marrowbusinessmedicine.drugAnticancer research
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Quantitative Ultrasound Bone Measurements in Pre-Pubertal Children with Type 1 Diabetes

2011

This case-control study aimed to assess bone status in children with type 1 diabetes mellitus (T1DM). Fifty-seven pre-pubertal patients (37 boys, aged 7.9 ± 2.5 years, T1DM duration 3.1 ± 1.6 years) and 171 age-matched healthy controls (111 boys) were studied. Quantitative ultrasound (QUS) was used to measure amplitude dependent speed of sound (Ad-SoS) at hand phalanges (expressed as standard deviation score [SDS]). Anthropometric and disease-related data (including mean HbA(1c) from whole T1DM duration [T], last year [Y], examination day [D]) were collected. Mean Ad-SoS SDS in patients -0.13 ± 1.32 (95% confidence interval [CI] -0.48, 0.22) was similar to that of controls. Subgroups discri…

MaleDiabetes durationmedicine.medical_specialtyHbA1cAcoustics and UltrasonicsBiophysicsSensitivity and SpecificityBone MeasurementsBone and BonesInternal medicineDiabetes mellitusmedicineHumansRadiology Nuclear Medicine and imagingChildBoneProspective cohort studyChildrenUltrasonographyType 1 diabetesRadiological and Ultrasound Technologybusiness.industryReproducibility of ResultsAnthropometrymedicine.diseaseConfidence intervalQuantitative ultrasoundDiabetes Mellitus Type 1Type 1 diabetesEndocrinologyChild PreschoolFemalebusinessQuantitative ultrasoundUltrasound in Medicine & Biology
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Dietary assessment methods in surveillance systems targeted to adolescents: A review of the literature

2019

Abstract Aims The present paper aims to identify ongoing multinational surveillance systems (SURSYSs) assessing diet and nutrition targeted to adolescents, including European surveys involving multiple countries and similar initiatives conducted in non-European countries with developed economies, and to describe the dietary assessment methods used. Data synthesis A total of 13 SURSYSs conducted in Europe, USA, Canada, Australia and New Zealand were identified. Dietary assessment methods commonly used include 24-h recalls (24H-Rs) and questionnaires or interviews. Food frequency questionnaires (FFQs) are used in combination with 24H-Rs in six SURSYSs: only FFQs are used in four SURSYSs; 24H-…

MaleDietary assessmentAdolescentEndocrinology Diabetes and MetabolismAdolescent Nutritional Physiological PhenomenaHealth BehaviorMedicine (miscellaneous)Nutritional Status030209 endocrinology & metabolism030204 cardiovascular system & hematologyRecommended Dietary AllowancesDietary habitDiet Surveys03 medical and health sciences0302 clinical medicineEnvironmental healthHumansSurveyAdolescence; Dietary consumption; Dietary habits; Surveillance system; Survey; Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Diet Surveys; Female; Humans; Male; Nutritional Status; Nutritive Value; Recommended Dietary Allowances; Reproducibility of Results; Adolescent Behavior; Diet Records; Diet Healthy; Feeding Behavior; Health BehaviorSurveillance systemHealthyNutrition and DieteticsFood frequencyDietary habitsData synthesisAge FactorsReproducibility of ResultsFeeding BehaviorAnthropometryDiet RecordsDietAdolescenceGeographyHomogeneousAdolescent BehaviorFruits and vegetablesDietary consumptionFemaleDiet HealthyCardiology and Cardiovascular MedicineNutritive ValueFast foods
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Pasireotide treatment reduces cardiometabolic risk in Cushing’s disease patients: an Italian, multicenter study

2018

Purpose: Patients with Cushing’s disease (CD) experience metabolic alterations leading to increased cardiovascular mortality. Recently, the visceral adiposity index (VAI) has been proposed as a marker of visceral adipose tissue dysfunction (ATD) and of the related cardiometabolic risk. We aimed to evaluate the impact of 12-month pasireotide treatment on cardiometabolic risk in CD patients. Methods: This is a multicentre, prospective, and observational study. Sixteen CD patients, referred to the Endocrine Units of the University Hospitals of Messina, Napoli, Padova, and Palermo (Italy), successfully treated with pasireotide for 12 month have been enrolled. In all patients, we assessed anthro…

MaleEndocrinology Diabetes and MetabolismCardiometabolic risk Cushing’s disease hypercortisolism pasireotide visceral adiposity indexLongitudinal StudieDisease030204 cardiovascular system & hematologySettore MED/13 - Endocrinologiachemistry.chemical_compound0302 clinical medicineEndocrinologyRisk FactorsMedicineLongitudinal StudiesProspective StudiesAdiposityFramingham Risk ScoreCushing’s diseaseCushing’s diseaseMiddle AgedPasireotideDiabetes and MetabolismHeart DiseaseItalyAtherosclerosiObesity AbdominalFemaleSomatostatinHumanAdultmedicine.medical_specialtyWaistHeart DiseasesHypercortisolism030209 endocrinology & metabolismIntra-Abdominal Fat03 medical and health sciencesMetabolic DiseasesInternal medicineDiabetes mellitusCardiometabolic risk; Cushing’s disease; Hypercortisolism; Pasireotide; Visceral adiposity index; Endocrinology Diabetes and Metabolism; EndocrinologyHumansPituitary ACTH Hypersecretionbusiness.industryRisk FactorCushing's diseaseAnthropometryAtherosclerosismedicine.diseasePasireotideCardiometabolic riskMetabolic DiseaseVisceral adiposity indexProspective StudiechemistryObservational studybusiness
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