Search results for "Pori"
showing 10 items of 761 documents
Phylogenetic relationship of ubiquitin repeats in the polyubiquitin gene from the marine sponge Geodia cydonium
1994
Ubiquitin is a 76-residue protein which is highly conserved among eukaryotes. Sponge (Porifera) ubiquitin, isolated from Geodia cydonium, is encoded by a gene (termed GCUBI) with six repeats, GCUBI-1 to GCUBI-6. All repeat units encode the same protein (with one exception: GCUBI-4 encodes ubiquitin with a change of Leu to Val at position 71). On the nt level the sequences of the six repeats differ considerably. All changes (except in GCUBI-4) are silent substitutions, which do not affect the protein structure. However, there is one major difference between the repeats: Codons from both codon families (TCN and AGPy) are simultaneously used for the serine at position 65. Using this characteri…
Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa
2005
The Mediterranean sponge Axinella verrucosa has been investigated for its alkaloid composition and has been found to produce a complex mixture of bromopyrrole alkaloids. Along with the previously isolated compounds 5-18, four novel alkaloids of this class, compounds 1-4, have been isolated, and their structures established through spectroscopic methods. Compounds 1-4 were found to display neuroprotective activity against the agonists serotonin and glutamate in vitro.
Host glycoprotein Gp96 and scavenger receptor SREC interact with PorB of disseminating Neisseria gonorrhoeae in an epithelial invasion pathway.
2007
Neisseria gonorrhoeae expresses numerous surface proteins that mediate bacterial adherence and invasion during infection. Gonococci expressing serotype A of the major outer membrane porin PorB (PorB(IA)) are frequently isolated from patients with severe disseminating infections. PorB(IA) triggers efficient adherence and invasion under low phosphate conditions mimicking systemic bloodstream infections. Here, we identify the human heat shock glycoprotein Gp96 and the scavenger receptor SREC as PorB(IA)-specific receptors. Gonococci expressing PorB(IA), but not those expressing PorB serotype B instead, bind to purified native or recombinant Gp96. Depletion of Gp96 from host cells prevented adh…
In vivo exposure of the marine sponge Chondrilla nucula Schmidt, 1862 to cadmium (Cd), copper (Cu) and lead (Pb) and its potential use for bioremedia…
2018
Abstract The study aimed to test the cadmium (Cd), copper (Cu) and lead (Pb) bioaccumulation capacity of the marine sponge Chondrilla nucula and to measure the expression of metallothioneins (MTs) by a western blotting assay to explore metal tolerance and its potential use as a bioremediator in contaminated coastal areas. C. nucula was sampled in a protected marine area in order to perform experiments on organisms living in a healthy environment. Under laboratory conditions, the sponges were exposed to increasing concentrations of Cd, Cu and Pb in tanks filled with artificial seawater set up for the experiments. For each metal, three waterborne concentrations (mgL−1) of Cd (0.02–0.04-0.08),…
Gestione sostenibile delle risorse marine: i Poriferi per la valutazione dello stato ambientale e per la depurazione delle acque. Studio di organismi…
The Messinian salinity crisis in the Mediterranean basin: A reassessment of the data and an integrated scenario
2006
Abstract After a long period of controversial debate about the interpretation of the Messinian salinity crisis (MSC), a near consensus existed since the ODP Leg 42A for a model keeping the major lines of the deep basin-shallow water model initially proposed by Hsu et al. (1973) . The knowledge of the crisis was improved since the 1995s by the availability of a very accurate astronomically calibrated timescale. The debate about its interpretation was then reactivated by several new scenarios that questioned most the major aspects of the previous classical models. The updated re-examination of the most salient features along with consideration of the hydrological requirements for evaporite de…
Lithostratigraphy of Sicily
2018
This book offers as comprehensive an overview as possible of the lithostratigraphy of the Italian region of Sicily, taking into account the multiplicity of formational and terminological variability developed over more than a century of studies and publications. It presents stratigraphic terminology, the geological lexicon and the main stratigraphic subdivisions that are not familiar to Sicilian geologists. The new stratigraphic methods and the use of formations as mapping units have prompted the acquisition of new lithostratigraphic data, and a review of the previous units and their comparison with the new collected data, enabling the definition of a number of new lithostratigraphic units.…
Ciminna, First Stop - 27 Thursday
2016
A description of the stratigraphic setting and tectonic evolution of the Late Neogene Ciminna basin (Northern Sicily)