Search results for "Positive Airway Pressure"

showing 10 items of 104 documents

Odontostomatological therapeutic possibilities in patients with sleep apnea

2009

Objectives: To evaluate the different therapeutic possibilities for treating Sleep Apnea/ Hypoapnea Syndrome (SAHS), as well as the effectiveness of such treatments, and to evaluate the epidemiological and clinical aspects of this syndrome. Study design: We carried out a meta-analytical, observational and retrospective study by selecting a total of 13 articles, which provided a sample size of 642 diagnosed cases of SAHS. Results: SAHS was more prevalent among males (88.7%) and the average age of diagnosis was 49.75 years old. In the majority of cases, these patients were found to be overweight, with an average body mass index of 28.32 Kg/ m². The average apnea / hypoapnea index was 31.64 ap…

AdultMalemedicine.medical_specialtyPediatricsmedicine.medical_treatmentOral MedicineOverweightYoung AdultSleep Apnea SyndromesEpidemiologymedicineHumansContinuous positive airway pressureGeneral DentistryAgedRetrospective Studiesbusiness.industryApneaSleep apneaRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPhysical therapyFemaleSurgeryObservational studymedicine.symptombusinessBody mass index
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Outcomes of uvulopalatopharyngoplasty with harmonic scalpel after failure of continuous positive airway pressure in sleep apnea syndrome.

2012

Our data highlight that uvulopalatopharyngoplasty (UPPP) with harmonic scalpel (HS) is a reliable treatment in selected patients affected by obstructive sleep apnea (OSA) and users of continuous positive airway pressure (CPAP).The aim of this paper was to verify the efficacy and applicability of UPPP with HS in the treatment of patients affected by OSA and users of CPAP.A total of 21 patients with a retropalatal obstruction and users of CPAP underwent UPPP with HS and were evaluated (before and 6 months after surgery) using the apnea/hypopnea index (AHI); oxygen desaturation index ≥4% (ODI(4)); Epworth Sleepiness Scale (ESS); snoring level (SL); subjective assessment of the postoperative pa…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentPostoperative painstomatognathic systemUltrasonic Surgical ProceduresmedicineHumansContinuous positive airway pressureTreatment FailureOxygen desaturation indexAgedSleep Apnea ObstructiveEpworth Sleepiness Scale; Obstructive sleep apnea; Oxygen desaturation index; Postoperative painContinuous Positive Airway Pressurebusiness.industryEpworth Sleepiness ScaleUvulopalatopharyngoplastySleep apneaApneaGeneral MedicineMiddle Agedmedicine.diseaseEpworth Sleepiness ScaleObstructive sleep apneaapnea/hypopnea indexnervous system diseasesrespiratory tract diseasesSurgeryObstructive sleep apneaOtorhinolaryngologyApnea–hypopnea indexUvulaAnesthesiaObstructive sleep apnea; apnea/hypopnea index; oxygen desaturation index; Epworth Sleepiness Scale; postoperative painPharynxFemalemedicine.symptomPalate SoftbusinessHypopneaActa oto-laryngologica
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Sleep apnoea and systemic hypertension

2010

Anti-hypertensive treatment cardiovascular risk continuous positive airway pressure treatment pathophysiology.Settore MED/10 - Malattie Dell'Apparato Respiratorio
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Sleep Apnea, Sleepiness, and Driving Risk

2019

Obstructive sleep apnea is associated with excessive daytime sleepiness in about 50% of cases, and with increased risk of driving accidents. Treatment with continuous positive airway pressure effectively decreases such risk, but compliance with continuous positive airway pressure treatment is often suboptimal. According to the European Union Directive on driving risk, retention of a driving license in patients with obstructive sleep apnea requires assessment of sleepiness and adherence to continuous positive airway pressure treatment, but there remains uncertainty on the optimal methods to assess sleepiness on a large scale.

Automobile Drivingmedicine.medical_specialtySleepinessmedicine.medical_treatmentDriving riskExcessive daytime sleepinessSubjective sleepineSettore MED/10 - Malattie Dell'Apparato RespiratorioObjective sleepine03 medical and health sciencesSleep Apnea SyndromesSleep Apnea Syndrome0302 clinical medicineRisk FactorsCPAPEpidemiologymedicineHumansmedia_common.cataloged_instanceContinuous positive airway pressureWakefulnessEuropean unionobstructive sleep apneapathophysiologymedia_commonContinuous Positive Airway Pressurebusiness.industryRisk FactorWakefulneSleep apneaGeneral Medicinemedicine.diseasesubjective sleepinessrespiratory tract diseasesObstructive sleep apneaPsychiatry and Mental healthClinical PsychologyNeuropsychology and Physiological Psychology030228 respiratory systemEmergency medicineobjective sleepinessPatient ComplianceepidemiologyNeurology (clinical)medicine.symptombusinessOptimal methods030217 neurology & neurosurgeryHumanSleep Medicine Clinics
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Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Coronavirus COVID-19 Pneumonia SARS-CoV-2 TocilizumabGCA Giant cell arteritispJIA Pediatric juvenile idiopathic arthritislaw.inventionchemistry.chemical_compound0302 clinical medicineRandomized controlled triallawMedicine030212 general & internal medicineClinical efficacyCPAP Continuous positive airway pressureCOVID-19 Coronavirus disease 2019IDSA Infectious Diseases Society of AmericaRA Rheumatoid arthritisTocilizumabIMV Invasive mechanical ventilationsJIA Juvenile idiopathic arthritisAIFA Agenzia Italiana del FarmacoPulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEAntibodies Monoclonal HumanizedNIH U.S. National Institutes of HealthArticleWHO World Health OrganizationSIMIT Italian Society of Infectious and Tropical disease03 medical and health sciencesTocilizumabARDS Acute respiratory distress syndromeAnimalsHumansIn patientIntensive care medicineTocilizumab ; COVID-19 ; Pneumonia ; SARS-CoV-2 ; Coronaviruslcsh:RC705-779business.industryCRS CAR-T cell-induced cytokine release syndromeInterleukin-6SARS-CoV-2NIV Noninvasive mechanical ventilationTNF Tumor necrosis factorCOVID-19Pneumonialcsh:Diseases of the respiratory systemCOVID-19 Drug TreatmentClinical trialCoronavirus030228 respiratory systemchemistrybusinessICTRP International Clinical Trials Registry PlatformPulmonology
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Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA coho…

2018

The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort. Patients with obstructive sleep apnea with positive airway pressure treatment from the European Sleep Apnea Database registry (n = 1, 415, 77% male, age 54 ± 11 [mean ± SD] years, body mass index 31.7 ± 6.4 kg/m2, apnea–hypopnea index 37 ± 24 n per hr, Epworth Sleepiness Scale 10.2 ± 5.0) were selected. Changes in body mass index and neck/waist/hip circumferences at baseline and at follow-up visit were analyse…

Data AnalysisMaleTime FactorsExcessive daytime sleepinessWeight Gainexcessive daytime sleepineBody Mass IndexCohort StudiesBehavioral Neuroscience0302 clinical medicinePositive airway pressureMedicineLongitudinal StudiesProspective Studiesobstructive sleep apneaSleep Apnea ObstructiveContinuous Positive Airway PressureEpworth Sleepiness ScaleSleep apneaGeneral MedicineMiddle Agedweight ; central obesity ; positive airway pressure ; obstructive sleep apnea ; ESADA cohortEuropeObesity AbdominalCardiologyFemaleWaist Circumferencemedicine.symptomAdultmedicine.medical_specialtyCognitive NeuroscienceSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicineHumanspositive airway pressureAgedcentral obesitybusiness.industryBody Weightbody weight central obesity excessive daytime sleepiness obstructive sleep apnea positive airway pressureta3121medicine.diseaseObesityrespiratory tract diseasesObstructive sleep apnea030228 respiratory systemHuman medicinebusinessBody mass indexWeight gain030217 neurology & neurosurgery
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Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: Longitudinal data from the European S…

2017

Introduction: The effect of continuous positive airway pressure (CPAP) treatment on body weight and central obesity in obstructive sleep apnea (OSA) patients is still unclear. Objectives: We aimed to study body composition change during CPAP treatment in the European Sleep Apnea Database (ESADA). Methods: OSA patients with a CPAP treatment follow-up time of more than 30 days in the ESADA registry were selected (n=2015). Body mass index (BMI), body weight, waist-, hip- and neck-circumferences were assessed at baseline and follow-up (median [interquartile range], 242 [380] days). Predictors for body composition changes with CPAP were analyzed adjusting for confounders. Results: Overall, there…

Databasebusiness.industrymedicine.medical_treatmentEpworth Sleepiness ScaleWeight changeSleep apneamedicine.diseasecomputer.software_genrenervous system diseasesrespiratory tract diseasesObstructive sleep apneaWeight lossPositive airway pressuremedicineContinuous positive airway pressuremedicine.symptombusinessWeight gaincomputerSleep and Control of Breathing
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Metabolic Consequences of Obstructive Sleep Apnea

2022

The effects of OSA on metabolism are quite complex, and obesity, diabetes, nonalcoholic fatty liver disease and dyslipidemia often coexist with OSA, making it difficult to tease out the independent effects of OSA on metabolic variables. There is firm experimental evidence of a detrimental impact of OSA on adipose tissue dysfunction, with intermittent hypoxia, sympathetic hyperactivity, and oxidative stress as the most important intermediate mechanisms. Sleep fragmentation or deprivation may also contribute to the metabolic dysfunction of OSA. This work reviews the current knowledge on this topic, as well as the results of studies on the effects of CPAP treatment.

InflammationDiabetes mellitu...CholesterolFree fatty acidInsulin resistanceContinuous positive airway pressure (CPAP)Settore MED/10 - Malattie Dell'Apparato RespiratorioCardiovascular riskMetabolic syndromeNonalcoholic fatty liver disease (NAFLD)
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[Respiratory muscle aids during an episode of aspiration in a patient with Duchenne muscular dystrophy].

2005

We report the case of a Duchenne muscular dystrophy patient with good bulbar function but severely decreased forced vital capacity (9%) and spontaneous peak cough flow (PCF) (2.35 L/s). The patient needed continuous noninvasive ventilation (NIV) consisting of a volumetric ventilator with a nighttime nasal mask and a daytime mouthpiece. He also required application of manually assisted coughing techniques by insufflation with a resuscitation bag and chest thrust (manually assisted PCF after maximum insufflation capacity of 4.33 L/s). An episode of serious food aspiration was resolved by his main caregiver through NIV and manually assisted coughing. Bronchoscopy under sedation using NIV with …

InsufflationAdultMaleResuscitationmedicine.medical_specialtyDuchenne muscular dystrophyPneumonia AspirationBronchoscopyRespiratory muscleMedicineHumansRespiratory systemMouthpieceChest thrustmedicine.diagnostic_testContinuous Positive Airway Pressurebusiness.industryGeneral Medicinemedicine.diseaseSurgeryMuscular Dystrophy DuchenneCoughInhalationAnesthesiabusinessRespiratory InsufficiencyArchivos de bronconeumologia
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Liver Steatosis and Fibrosis in OSA patients After Long-term CPAP Treatment: A Preliminary Ultrasound Study.

2015

In cases of morbid obesity, obstructive sleep apnea (OSA) was associated with biopsy-proven liver damage. The role of non-invasive techniques to monitor liver changes during OSA treatment with continuous positive airway pressure (CPAP) is unknown. We used non-invasive ultrasound techniques to assess liver steatosis and fibrosis in severe OSA patients at diagnosis and during long-term CPAP treatment. Fifteen consecutive patients with severe OSA (apnea hypopnea index 52.5 ± 19.1/h) were studied by liver ultrasound and elastography (Fibroscan) at 6-mo (n = 3) or 1-y (n = 12) follow-up. Mean age was 49.3 ± 11.9 y, body mass index (BMI) was 35.4 ± 6.4 kg/m(2). Adherence to CPAP was ≥5 h/night. A…

Liver CirrhosisMalemedicine.medical_specialtyAcoustics and Ultrasonicsmedicine.medical_treatmentBiophysicsSettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyBody Mass IndexTime03 medical and health sciences0302 clinical medicineFibrosisInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingObesityContinuous positive airway pressureNon-invasive assessmentUltrasonographySleep Apnea ObstructiveRadiological and Ultrasound Technologymedicine.diagnostic_testContinuous Positive Airway Pressurebusiness.industryFatty liverLiver fibrosiMiddle Agedmedicine.diseaseObstructive sleep apneanervous system diseasesrespiratory tract diseasesSurgeryObstructive sleep apneaFatty Liver030228 respiratory systemApnea–hypopnea indexLiverLiver steatosiFeasibility Studies030211 gastroenterology & hepatologyFemaleElastographyLongitudinal studySteatosisbusinessBody mass indexUltrasound in medicinebiology
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