Search results for "Positron"
showing 10 items of 1346 documents
Imaging of Gastrointestinal Stromal Tumors: From Diagnosis to Evaluation of Therapeutic Response
2016
Once considered an obscure tumor entity with poor prognosis, gastrointestinal stromal tumors (GISTs) are nowadays recognized as the most common mesenchymal tumors of the alimentary tract. GISTs differ from other mesenchymal neoplasms at pathology since 90% of them exhibit strong immunohistochemical staining for KIT, a tyrosinase kinase growth factor receptor. In the early 2000s, the ability of imatinib mesylate, a tyrosine kinase inhibitor, to inhibit KIT established a new paradigm for cancer treatment. A reduction in lesion size may not be observed or may appear many months after therapy; thus, tumor response criteria alternative to the Response Evaluation Criteria in Solid Tumors were dev…
(R)-NODAGA-PSMA: A Versatile Precursor for Radiometal Labeling and Nuclear Imaging of PSMA-Positive Tumors
2015
Purpose The present study aims at developing and evaluating an urea-based prostate specific membrane antigen (PSMA) inhibitor suitable for labeling with 111In for SPECT and intraoperative applications as well as 68Ga and 64Cu for PET imaging. Methods The PSMA-based inhibitor-lysine-urea-glutamate-coupled to the spacer Phe-Phe-D-Lys(suberoyl) and functionalized with the enantiomerically pure prochelator (R)-1-(1-carboxy-3-carbotertbutoxypropyl)-4,7-carbotartbutoxymethyl)-1,4,7-triazacyclononane ((R)-NODAGA(tBu)3), to obtain (R)-NODAGA-Phe-Phe-D-Lys(suberoyl)-Lys-urea-Glu (CC34). CC34 was labeled with 111In, 68Ga and 64Cu. The radioconjugates were further evaluated in vitro and in vivo in LNC…
Welche Eigenschaften machen ein Neuroleptikum "atypisch"?
2001
Die Gruppe der “atypischen” Neuroleptika ist keine einheitliche Substanzklasse, sondern sowohl nach pharmakologischen als auch nach klinischen Kriterien sehr heterogen. Die Ubergange von dem prototypischen “atypischen” Neuroleptikum Clozapin zu den “konventionellen” Neuroleptika erscheinen fliesend. Anhand der praklinischen Besonderheiten dieser Substanzen und ihrer Charakteristika in SPECT- und PET-Studien werden die wesentlichen Konzepte diskutiert, die man heute fur die “Atypie” eines Neuroleptikums verantwortlich macht. Dazu zahlen insbesondere der kombinierte Antagonismus von D2-artigen Dopamin- und 5-HT2-Serotoninrezeptoren und die praferentielle Beeinflussung mesolimbischer dopaminer…
Measurement of $\Delta^{++}$(1232) production in hadronic Z decays
1995
A measurement of the \Delta^{++}(1232) inclusive production in hadronic decays of the Z at LEP is presented, based on 1.3 million hadronic events collected~ by the DELPHI~ detector in the 1994 LEP running~ period. The DELPHI ring imaging Cherenkov counters are used for identifying hadrons. The average \Delta^{++}(1232) multiplicity per hadronic event is 0.079 \pm 0.015 which is more than a factor of two below the JETSET, HERWIG and UCLA model predictions. It agrees with a recently proposed universal mass dependence of particle production rates in e^{+}e^- annihilations.
Measurement of the Branching Fractions of ExclusiveB¯→D(*)(π)l−ν¯lDecays in Events with a Fully ReconstructedBMeson
2008
We report a measurement of the branching fractions for _B-->D(*)(pi)l- _nu(l) decays based on 341.1 fb(-1) of data collected at the Upsilon(4S) resonance with the BABAR detector at the SLAC PEP-II e+ e- storage rings. Events are tagged by fully reconstructing one of the B mesons in a hadronic decay mode. We obtain B(B- -->D(0)l-_nu(l)=(2.33+/-0.09(stat)+/-0.09(syst)%, B(B- -->D(*0)l-_nu(l)=(5.83+/-0.15(stat) +/-0.30(syst) %, B(_B(0)-->D+l-_nu(l)=(2.21+/-0.11(stat) +/-0.12(syst)%, B(_B(0)-->D(*)l-_nu(l)=(5.49+/-0.16(stat)+/-0.25(syst)%, B(B- -->D+pi-l-_nu(l)=(0.42+/-0.06(stat)+/-0.03(syst)%, B(B- -->D(*)+pi-l-_nu(l)=(0.59+/-0.05(stat)+/-0.04(syst)%, B(_B(0)-->D(0)pi+l-_nu(l)=(0.43+/-0.08(sta…
Dalitz plot analysis ofD0→K¯0K+K−
2005
A Dalitz plot analysis of approximately 12500 D0 events reconstructed in the hadronic decay D0-->K0bar K+ K- is presented. This analysis is based on a data sample of 91.5 fb-1 collected with the BaBar detector at the PEP-II asymmetric-energy e+ e- storage rings at SLAC running at center-of-mass energies on and 40 MeV below the Y4S resonance. The events are selected from e+ e- --> c cbar annihilations using the decay D*+ --> D0 pi+. The following ratio of branching fractions has been obtained: BR = Gamma(D0-->K0bar K+ K-)/Gamma(D0-->K0bar pi+ pi-) = (15.8+/-0.1(stat.)+/-0.5(syst.)x 10-2 Estimates of fractions and phases for resonant and non-resonant contributions to the Dalitz plot are also …
Search for the rare charmless hadronic decayB+→a0+π0
2008
We present a search for B decays to a charged scalar meson a0+ and a pi0 where the a0+ decays to an eta meson and a pi+. The analysis was performed on a data sample consisting of 383x10-6 BBbar pairs collected with the Babar detector at the PEP-II asymmetric-energy B Factory at SLAC. We find no significant signal and set an upper limit on the product branching fraction BF[(B+ -> a0+ pi0) x (a0+ -> eta pi+)] of 1.4x10-6 at the 90% confidence level.
Semi-inclusive tau decays involving the vector or axial-vector hadronic currents
1993
7 páginas, 1 figura, 4 tablas.
Model-independent search for the decay B^{+}→l^{+}ν_{l}γ
2009
We present a search for the radiative leptonic decay B^+ → l^+ν_lγ, where l = e, μ, using a data sample of 465 × 10^6 BB(overbar) pairs collected by the BABAR experiment. In this analysis, we fully reconstruct the hadronic decay of one of the B mesons in Υ(4S) → B^+B^- decays, then search for evidence of B^+ → l^+ν_lγ in the rest of the event. We observe no significant evidence of signal decays and report model-independent branching fraction upper limits of B(B^+ → e^+ν_eγ) < 17 × 10^(-6), B(B^+ → μ^+ν_μγ) < 24 × 10^(-6), and B(B^+ → l^+ν_lγ) < 15.6 × 10^(-6) (l= e or μ), all at the 90% confidence level.
Measurements of absolute hadronic branching fractions of the Λc+ baryon
2016
Kolcu, Onur Buğra (Arel Author) --- Makale 69 yazarlıdır.