Search results for "Potassium"

showing 10 items of 930 documents

Inhibition of neuroeffector transmission in human vas deferens by sildenafil

2000

Sildenafil (0.1 - 30 microM), a cyclic GMP phosphodiesterase 5 (PDE 5) inhibitor, induced inhibition of electrically evoked contractions of ring segments of human vas deferens from 34 vasectomies. Zaprinast (0.1 - 100 microM), another PDE 5 inhibitor, and the nitric oxide (NO) donor sodium nitroprusside (SNP) (0.1 - 100 microM) had no effect on neurogenic contractions. The inhibition induced by sildenafil was not modified by the inhibitor of guanylate cyclase 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one (ODQ) (1 - 30 microM) but it was abolished by the K(+) channel blockers tetraethylammonium (TEA, 1 mM), iberiotoxin (0.1 microM) and charybdotoxin (0.1 microM). Sildenafil, zaprinast and SNP…

Pharmacologymedicine.medical_specialtyTetraethylammoniumVas deferensIberiotoxinPotassium channelPDE5 drug designchemistry.chemical_compoundEndocrinologymedicine.anatomical_structurechemistryInternal medicinemedicineChannel blockerSodium nitroprussideZaprinastmedicine.drugBritish Journal of Pharmacology
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K+ and Na+ effects on the gelation properties of κ-Carrageenan

2004

The effects of K(+), Na(+) ions and their mixture on the conformational transition and macroscopic gel properties of kappa-Carrageenan system have been studied using different experimental techniques. The macroscopic gelation properties of kappa-Carrageenan were found to be dependent upon cosolute type. Indeed, a more ordered and strong gel was obtained in the presence of K(+) with respect to Na(+) ions. The gel properties obtained using mixtures of two cosolutes are shown to depend on the [K(+)]/[Na(+)] ratio.

Phase transitionTime FactorsKappa-CarrageenanChemistrySodiumOrganic ChemistryTemperatureBiophysicsκ carrageenanSodium ChlorideCarrageenanBiochemistryPhase TransitionPotassium ChlorideIonCrystallographyRheologyCationsPotassiumPhysical chemistrySelf-assemblyRheologyGelsBiophysical Chemistry
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Quantum chemical modelling of perovskite solid solutions

2000

In line with our previous study (Eglitis R I et al 1998 J. Phys.: Condens. Matter 10 6271) for a single Nb impurity and Nb clusters in KTaO3 we present here the results of calculations for a series of perovskite KNbx Ta 1−x O3 (KTN) solid solutions (x = 0, 0.125, 0.25, 0.75, and 1). The quantum chemical method of the intermediate neglect of the differential overlap (INDO) combined with the large unit cell (LUC) periodic model is used. According to the INDO calculations, Nb impurity becomes off-centre in KTaO3 already at the lowest studied Nb concentration. Its off-centre displacement is in a good agreement with XAFS measurements. We compare our results with previous FP-LMTO calculations. Pe…

Phase transitionchemistry.chemical_compoundPotassium niobateCondensed matter physicsChemistryPhononImpurityGeneral Materials ScienceElectronic structureCondensed Matter PhysicsFerroelectricitySolid solutionPerovskite (structure)Journal of Physics: Condensed Matter
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Prevention of the acute neurotoxic effects of phenytoin on rat peripheral nerve by H7, an inhibitor of protein kinase C.

1992

Abstract The neurotoxic effects of a single dose of phenytoin (150 mg/kg body weight) alone or 30 min after H7 (a protein kinase C inhibitor) injection (20 mg/kg body weight) were investigated in terms of peripheral neuromuscular function and Na + ,K + -ATPase activity of the sciatic nerve. This intraperitoneal injection of phenytoin induced complete blockade of muscle action potentials in the dorsal segmental muscles of the rat tail evoked by electric stimulation of the caudal nerve and a 40% decrease in the Na + ,K + -ATPase activity of the rat sciatic nerve when compared with control values, measured as the difference between total and ouabain-insensitive ATPase activity. Prior administr…

PhenytoinMalemedicine.medical_treatmentIntraperitoneal injectionPharmacologyToxicologyNeuromuscular junctionPiperazines1-(5-Isoquinolinesulfonyl)-2-MethylpiperazinemedicineAnimalsPeripheral NervesNa+/K+-ATPaseRats WistarProtein kinase CProtein Kinase CbiologyChemistryIsoquinolinesSciatic NerveElectric StimulationRatsElectrophysiologymedicine.anatomical_structureAnticonvulsantEnzyme inhibitorAnesthesiaPhenytoinbiology.proteinSciatic nerveSodium-Potassium-Exchanging ATPaseInjections Intraperitonealmedicine.drugToxicology
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Modulation of neuronal phospholipase D activity under depolarizing conditions

1999

Neuronal phospholipase D (PLD) activity was hypothesized to be involved in vesicle trafficking and endocytosis and, possibly, transmitter release. We here report that prolonged depolarization of rat hippocampal slices by potassium chloride (KCl) or 4-aminopyridine inhibited PLD activity. Similarly, PLD activity in rat cortical synaptosomes was significantly inhibited by depolarizing agents including veratridine and ouabain. Inhibition of calcium/calmodulin kinase II (CaMKII) which positively modulates synaptosomal PLD activity [Sarri et al. (1998) FEBS Lett. 440, 287-290] by KN-62 caused a further reduction of PLD activity in depolarized synaptosomes. Depolarization-induced inhibition of PL…

Phosphatidylinositol 45-DiphosphateTime FactorsBiophysicschemistry.chemical_elementCalciumHippocampusBiochemistryOuabainMembrane PotentialsPotassium Chloridechemistry.chemical_compoundStructural BiologyCa2+/calmodulin-dependent protein kinaseSynaptosomeElectrochemistryPhospholipase DGeneticsmedicineAnimalsPhospholipase D activityEnzyme InhibitorsRats WistarMolecular BiologyProtein Kinase CProtein Synthesis InhibitorsSynaptosomePhospholipase DCalcium/calmodulin-dependent protein kinase IINeomycinDepolarizationPhosphatidylinositol-45-bisphosphateCell BiologyRatsCell biologyenzymes and coenzymes (carbohydrates)chemistryCalcium-Calmodulin-Dependent Protein KinasesDepolarizationlipids (amino acids peptides and proteins)VeratridineSynaptosomesmedicine.drugFEBS Letters
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Measurement of the atmospheric muon flux with a 4 GeV threshold in the ANTARES neutrino telescope

2010

A new method for the measurement of the muon flux in the deep-sea ANTARES neutrino telescope and its dependence on the depth is presented. The method is based on the observation of coincidence signals in adjacent storeys of the detector. This yields an energy threshold of about 4 GeV. The main sources of optical background are the decay of 40K and the bioluminescence in the sea water. The 40K background is used to calibrate the efficiency of the photo-multiplier tubes.

PhotomultiplierPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaAtmospheric muonsFOS: Physical sciencesLINECosmic rayPotassium-4001 natural sciencesParticle detectorNuclear physicsPOTASSIUM-40NEUTRINO TELESCOPESatmospheric muons; depth intensity relation; potassium-400103 physical sciencesDepth intensity relation14. Life underwater010306 general physicsInstrumentation and Methods for Astrophysics (astro-ph.IM)ATMOSPHERIC MUONSPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)010308 nuclear & particles physicsPotassium-40DetectorAstrophysics::Instrumentation and Methods for AstrophysicsAstronomy and AstrophysicsPERFORMANCEDEPTH INTENSITY RELATIONLIGHTNeutrino detector13. Climate actionddc:540Física nuclearHigh Energy Physics::ExperimentNeutrinoAstrophysics - High Energy Astrophysical PhenomenaAstrophysics - Instrumentation and Methods for Astrophysics[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]SYSTEMLepton
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Charoite, as an example of a structure with natural nanotubes

2012

Charoite from the Murun massif in Yakutiya, Russia (Vorob’ev 2008) was investigated using automated electron diffraction tomography (ADT) (Kolb et al. 2007, 2008; Mugnaioli et al. 2010) and precession electron diffraction (PED) (Mugnaioli et al. 2010, 2009), which allowed to determine the structure of charoite for the first time. The structure was solved ab initio in space group P21/m by direct methods using a fully kinematic approach. The least squares refinements with 2878 reflections F(hkl) >4s F converged to unweighted/weighted residuals R 1/wR 2 • 0.173/0.21 (Rozhdestvenskaya et al. 2010).

PhysicsBoron Nitride; Mirror Plane; Potassium Atom; Apical Oxygen; Kinematic ApproachApical OxygenAnalytical chemistryStructure (category theory)Ab initioengineering.materialLeast squaresPotassium AtomElectron diffractionCharoiteDirect methodsengineeringPrecession electron diffractionBoron NitrideKinematic ApproachBoron Nitride Mirror Plane Potassium Atom Apical Oxygen Kinematic ApproachMirror planeMirror Plane
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Precision measurements of the charge radii of potassium isotopes

2019

International audience; Precision nuclear charge radii measurements in the light-mass region are essential for understanding the evolution of nuclear structure, but their measurement represents a great challenge for experimental techniques. At the Collinear Resonance Ionization Spectroscopy (CRIS) setup at ISOLDE-CERN, a laser frequency calibration and monitoring system was installed and commissioned through the hyperfine spectra measurement of $^{38–47}$K. It allowed for the extraction of the hyperfine parameters and isotope shifts with better than 1 MHz precision. These results are in excellent agreement with available literature values and they demonstrate the suitability of the CRIS tec…

PhysicsIsotope010308 nuclear & particles physicsNuclear structure[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]Nuclear Structure01 natural sciences7. Clean energyEffective nuclear chargeSpectral linenuclear charge distributionIsotopes of potassium0103 physical sciencesCalibrationlaser spectroscopyNuclear Physics - Experimentfine and hyperfine structurePhysics::Atomic Physicsatomic spectraAtomic physics010306 general physicsSpectroscopyydinfysiikkaHyperfine structurePhysical Review C
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Spectroscopy of very neutron-deficient 187,189Bi isotopes

2003

Shape coexistence is well known to occur in nuclei, in particular near closed shells [1], where particle-hole excitations across the shell gap can create deformed intruder states. In the neutron-deficient lead isotopes (Z = 82), deformed structures appear at low excitation energy. The isotope 188Pb [2] shows for example a triple shape coexistence with oblate and prolate excited 0+ states that compete with the spherical ground state. The study of the odd-proton single-particle excitations in Bi isotopes allows to obtain information on the orbitals involved in the different shapes observed in this mass region.

PhysicsIsotopes of potassiumIsotopeAtomic orbitalExcited stateNuclear TheoryNeutronNuclear ExperimentGround stateSpectroscopyMolecular physicsExcitation
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Differentielle Wirkungsquerschnitte für die elastische Streuung niederenergetischer Elektronen an Kalium

1971

The elastic differential cross sections of electrons scattered by potassium has been measured over the angular range from 25 ° to 150 ° and with electron energies between 0.9 and 15 eV. The results are compared with other experimental data and with theoretical values. The agreement is only partly satisfactory.

PhysicsNuclear and High Energy PhysicsAngular rangechemistryPotassiumNuclear fusionchemistry.chemical_elementElectronAtomic physicsZeitschrift für Physik A Hadrons and nuclei
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