Search results for "PreP"

showing 10 items of 1334 documents

Self‐management of immunomodulatory drug treatment in multiple myeloma patients

2019

Objective Immunomodulatory drugs (IMIDs: thalidomide, lenalidomide and pomalidomide) are widely used in patients with multiple myeloma (MM). The aim of our study was to validate a questionnaire to evaluate the self-capacity of MM patients to manage IMID treatment including side effects. Methods We used a method adapted from the recommendations of the European Organisation for Research and Treatment of Cancer (EORTC) to validate a French questionnaire for patients with MM treated with IMIDs. Results The face validity was evaluated in 15 patients and the construct validity in 56 patients. For discriminant validity, two groups were constituted by gender and depending on whether they had a prev…

medicine.medical_specialtybusiness.industrySelf-ManagementDiscriminant validityReproducibility of ResultsConstruct validityPomalidomidemedicine.diseaseThalidomide03 medical and health sciences0302 clinical medicinePharmaceutical PreparationsOncologyConvergent validity030220 oncology & carcinogenesisInternal medicinemedicineHumansMultiple MyelomabusinessLenalidomideMultiple myelomaFace validitymedicine.drugLenalidomideEuropean Journal of Cancer Care
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Absorption of drugs from the bladder and intravesical chemotherapy

1976

medicine.medical_specialtybusiness.industryUrologyUrinary BladderUrologyAntineoplastic AgentsPharmaceutical PreparationsUrinary Bladder NeoplasmsInjections IntravenousAnimalsHumansMedicineRabbitsIntravesical chemotherapybusinessAbsorption (electromagnetic radiation)ThiotepaUrological Research
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Dentists' practice and compliance with current guidelines of infective endocarditis prophylaxis- National survey study

2021

Background The objective of this study was to assess the attitude, practice, and knowledge of Croatian dentists regarding infective endocarditis (IE) prophylaxis. Material and methods A cross-sectional, self-reporting questionnaire survey was conducted with the participation of 348 Croatian dentists. The questionnaire was designed to collect information on participants' work experience, place of work, their attitudes related to the treatment of IE-risk patients, knowledge and adherence to IE antibiotic prophylaxis guidelines. Results Knowledge and adherence to the current guidelines decreased with the higher years of experience. Compliance with the current guidelines varied, mostly because …

medicine.medical_specialtybusiness.industryantibiotic prophylaxis ; dentistry ; infective endocarditisResearchSpecialtyMEDLINEQuestionnairemedicine.diseaseCommunity and Preventive DentistryWork experienceCompliance (psychology)PreparednessFamily medicineInfective endocarditisMedicineAntibiotic prophylaxisbusinessGeneral DentistryUNESCO:CIENCIAS MÉDICAS
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Anthracyclines and regional myocardial damage in breast cancer patients. A multicentre study from the Working Group on Drug Cardiotoxicity and Cardio…

2021

Abstract Aims In breast cancer (BC) patients treated with anthracyclines-based therapies, we aim at assessing whether adjuvant drugs impact cardiac function differently and whether their cardiotoxicity has a regional pattern. Methods and results In a multicentre study, 146 BC patients (56 ± 11 years) were prospectively enrolled and divided into three groups according to the received treatments: AC/EC-Group (doxorubicin or epirubicin + cyclophosphamide), AC/EC/Tax-Group (AC/EC + taxanes), FEC/Tax-Group (fluorouracil + EC + taxanes). Fifty-six patients of the total cohort also received trastuzumab. Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) were calculated …

medicine.medical_specialtymedicine.medical_treatmentPopulationCardiologyBreast NeoplasmsAnthracyclineAnthracyclines; Breast cancer; Cardiotoxicity; Myocardial strain030204 cardiovascular system & hematologyAnthracyclines Breast cancer Breast Neoplasms Cardiology Cardiotoxicity Echocardiography Female Humans italy Myocardial strain Pharmaceutical Preparations Stroke Volume Trastuzumab Ventricular Function Left Ventricular Dysfunction LeftVentricular Function LeftVentricular Dysfunction Left03 medical and health sciencesBreast cancer0302 clinical medicineTrastuzumabInternal medicineHumansMedicineAnthracyclinesRadiology Nuclear Medicine and imagingeducationeducation.field_of_studyChemotherapyCardiotoxicityEjection fractionbusiness.industryStroke VolumeGeneral MedicineTrastuzumabMyocardial strainChemotherapy regimenCardiotoxicityItalyPharmaceutical PreparationsEchocardiographyFluorouracil030220 oncology & carcinogenesisCardiologyFemaleCardiology and Cardiovascular Medicinebusinessmedicine.drugEpirubicinEuropean Heart Journal - Cardiovascular Imaging
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Does anti-inflammatory drugs modify the severe odontogenic infection prognosis? A 10-year’s experience

2020

Background Numerous biochemical datas support the noxious role of anti-inflammatory drugs on immune response. Those observations are often put forward for unfavorable evolution of odontogenic infection but has never been really proven in clinic. The aim of this study is to try to clarify this role based on the collection of the clinical course of odontogenic infections over a 10-year analysis period. Material and Methods The investigators implemented a prospective observational study. The sample was composed of patients managed between January 2004 and December 2014 for severe odontogenic infection based on three criteria: hospital admission, intravenous antibiotic therapy, tooth extraction…

medicine.medical_specialtytumorErythemamedicine.drug_classMESH: Pharmaceutical PreparationsPopulationAnti-Inflammatory AgentsPaincarcinomaMESH: Prognosislip03 medical and health sciences0302 clinical medicine[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesInternal medicinemedicineHumanseducationGeneral DentistryUNESCO:CIENCIAS MÉDICASOdontogenic infectioncystUnivariate analysiseducation.field_of_studyMESH: Humansbusiness.industryResearchAnti-Inflammatory Agents Non-Steroidal030206 dentistrymedicine.diseasePrognosisMESH: Anti-Inflammatory Agents Non-SteroidalOtorhinolaryngologyPharmaceutical PreparationsMESH: Anti-Inflammatory AgentsPropensity score matching[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesCorticosteroidSurgeryObservational studyMESH: Painmedicine.symptomOral SurgerybusinessOdynophagianeoplasm
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La representación social del medio rural en la geografía escolar

2016

Esta memoria de investigación se fundamenta en un método comparativo en la que se analizan las representaciones sociales del medio rural de estudiantes de cuarto curso de educación secundaria. Hemos escogido un centro experimental rural (IES Nº1 de Requena) y dos centros de contraste: urbano (IES San Vicent Ferrer) y periurbano (Colegio Pléyade). A partir de la interpretación de los resultados de las encuestas y de los esquemas mentales, y del análisis de una entrevista semiestructurada y los libros de texto, se ha demostrado que el currículo escolar es un obstáculo al conocimiento de las percepciones sociales del alumnado. Las similitudes y diferencias respecto de la práctica social y el e…

medio ruralmétodo comparativoinvestigaciónrepresentaciones socialeseducación secundaria580302 Preparación de profesores
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Problemas enrevesados

2014

Se revisan los diversos modos de razonamiento de las personas con el ánimo de llegar a ser deliberadamente consciente de ellos y poder alcanzar así los niveles más valiosos de racionalidad para resolver los problemas que verdaderamente tienen interés, los mal estructurados.

metacogniciónracionalidadUNESCO::PEDAGOGÍA::Preparación y empleo de profesores:PEDAGOGÍA::Preparación y empleo de profesores [UNESCO]educaciónproblemas mal estructuradosjuicios reflexivos
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Cukura diabēta preparātu aprite Ogres aptiekā

2021

Diabets mūsdienās ir ļoti populāra un strauji attīstoša saslimšana visā pasaulē. Katru gadu pieaaug saslimušo cilvēku skaits un tas nav atkarīgi no sociāla slāņa piederības. Šajā darbā tiek apskatīta slimības vēsture, tipi, galvenās pazīmes kā arī ārstēšanas iespējas. Praktiskā daļā tiek analizēta biguanīda grupas perorālie pretdiabēta līdzekļi ar dažādiem nosaukumiem un vairākām devam.

metformīnsmedikamentoza ārstēšanaFarmācijacukura diabētspreparātu aprite aptiekā
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Adapter stabilizujący do długich preparatów mikroskopowych – budowa i zastosowanie w cyfrowym pozyskiwaniu obrazu

2018

Możliwość wykonywania, za pomocą mikrotomu typu „core--microtome”,preparatów z całych wywiertów wygenerowała problem związany ze stabilizacją preparatów podczas procesu pozyskiwania i zapis ich obrazu. Zaproponowane ostatnio dwa adaptery do długich preparatów mikroskopowych rozwiązały problem ich stabilizacji oraz umożliwiły kontrolę pozycji docelowych fragmentów w polu widzenia obiektywu. Konstrukcje te nie rozwiązują wszystkich potrzeb pojawiających się podczas pozyskiwania obrazu na potrzeby ilościowej anatomii drewna. W artykule proponujemy udoskonaloną wersję adaptera do długich preparatów mikroskopowych wychodzącą naprzeciw potrzebom użytkowników wcześniejszych wersji. Konstrukcje te …

mikroskopia świetlnailościowa anatomia drewnapreparatyka mikroskopowaakwizycja obrazuquantitative wood anatomyimage acquisitionmicro sectioninglight microscopyStudia i Materiały Centrum Edukacji Przyrodniczo-Leśnej
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Jonizējoša starojuma monitoringa principi kodolmedicīnā strādājošiem, veicot skeleta scintigrāfiju

2019

Bakalaura darba tēma ir “ Jonizējoša starojuma monitoringa principi kodolmedicīnā strādājošiem, veicot skeleta scintigrāfiju”. Bakalaura darbs sastāv no ievada, piecām daļām, secinājumiem un pielikumiem. Tēmas aktualitāti nosaka strauji pieaugošs onkoloģisko saslimšanu skaits, kā arī arvien vairāk slimniekiem tiek ordinēta skeleta scintigrāfija. Turklāt, ne mazāk svarīgs ir regulārs jonizējošā starojuma monitorings, lai personālam samazinātos iespējamība saņemt palielinātu starojuma dozu. Bakalura darba pētījumam tika izvirzīts sekojošs mērķis: noskaidrot jonizējoša starojuma mnonitoringa principus kodlmedicīnā strādājošiem, veicot skeleta scintigrāfiju. Uzstādītais pētījuma jautājums: piea…

monitoringa pamatprincipiradionuklīdā diagnostikaskeleta scintigrāfijaradiofarmpreparātiMedicīnaradiācijas aizsardzība
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