Search results for "PreP"
showing 10 items of 1334 documents
Dynamics of Changes in Preschool Teacher Preparation Programs (1950-2010)
2015
<p>Each period is characterized by its specific features which are the base for forming learning values, educational process principles for higher education, educational aims for future teachers. The development of pedagogy subject as an academic discipline is a prime example of political and social developments of society impact.<br />The preparation of professional pre-school teacher and the implementation of the curriculum are topical problems in previous and current Latvian socio-economic and educational context. Changes in preschool teacher preparation program design and implementation are given an opportunity to compare, try and select the most valuable to fit the today’s …
Are We Really Teaching English for Specific Purposes, or Basic English Skills? The Cases of Turkey and Latvia
2018
English for specific purposes (ESP) has evolved as an important sub-field of English language education to meet the career-related needs of non-native speakers of English in a wide variety of contexts. As such, ESP instruction in specialized subject areas ranging from vocational (e.g., tourism and hospitality) to professional (e.g., international law or banking) to academic (e.g., thesis and dissertation writing) is often integrated in the training and degree programs offered at higher education institutions. However, the ability of these institutions to provide adequate ESP instruction has often been called into question, with critics indicating that insufficient resources and planning, la…
Rapporti di reggenza? Una descrizione ambivalente nella tradizione grammaticale tardoantica e medioevale
2023
This study aims to shed light on the historical development of a linguistic theory with reference to syntax in Late Antiquity and the Middle Ages, through an investigation of grammatical works related to Donatus, since a reflection on syntax emerges from the commentaries and from other grammatical works connected with his artes. This investigation focuses on the description of the government relation between praepositio and casus, through a preliminary collection of the occurrences of both terms with the Cross Database Searchtool of Brepols Publishers as a digital tool, and based on a textual analysis of the de praepositione sections included in a selection of grammatical works ranging from…
Thermoplastic Properties of Endodontic Gutta-percha: A Thermographic In Vitro Study
2014
Abstract Introduction Endodontic gutta-percha undergoes deformation at temperatures above 65°C. The temperature influence of heat carriers on gutta-percha cones was investigated in vitro. Methods Six single-rooted extracted teeth were embedded in resin and fixed. The root canals were prepared (ProFile; Dentsply Maillefer, Ballaiques, Switzerland) to different tapers and bisected. Thermographic images when heating the gutta-percha cones (Roeko, Langenau, Germany) with a heat carrier (ML .12; SybronEndo, Orange, CA) at 1 and 5 mm from the working length were made with an infrared thermal imaging camera (ThermaCam P640; Flir Systems, Taby, Sweden). The device temperature was preset at 200°C. T…
Assembly and encapsulation of coordination tectons driven by hydrogen-bondingand space-filling
2001
[FR] Le composé ¿Fe(LI)3¿2¿Fe(H2O)6¿(ClO4)6 (2), LI = 1,10-phénanthroline-5,6-dione, a été synthétisé et caractérisé. La structure cristalline 2 est définie par un assemblage bidimensionnel non covalent, peu commun, constitué par des tectons chiraux ¿Fe(LI)3¿2+, assemblés par des cations ¿Fe(H2O)6¿2+ encapsulés dans des cages. Ces cages sont formées par 12 liaisons hydrogène établies entre les molécules d¿eau coordinées et les groupes dione appartenant à six molecules chirales ¿Fe(LI)3¿2+ ¿, ¿ alternées.
Gated mesoporous silica nanoparticles for the controlled delivery of drugs in cancer cells
2015
In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation of therapeutic agents, enhancing their bioavailability and overcoming common issues such as poor water solubility and poor stability of some drugs. In particular, redox-responsive delivery systems have attracted the attention of scientists because of the intracellular reductive environment related to a high concentration of glutathione (GSH). In this context, we describe herein the development of a GSH-responsive delivery system based on poly(ethylene glycol)- (PEG-)…
Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles
2014
N&uacute;ria Mas,1&ndash;3 Irene Galiana,3 Silvia Hurtado,&dagger; Laura Mondrag&oacute;n,1&ndash;3 Andrea Bernardos,1&ndash;3 F&eacute;lix Sancen&oacute;n,1&ndash;3 Mar&iacute;a D Marcos,1&ndash;3 Pedro Amor&oacute;s,4 Nuria Abril-Utrillas,5 Ram&oacute;n Mart&iacute;nez-M&aacute;&ntilde;ez,1&ndash;3 Jos&eacute; Ram&oacute;n Murgu&iacute;a1,3 1Centro de Reconocimiento Molecular y Desarrollo Tecnol&oacute;gico (IDM), Centro Mixto Universidad Polit&eacute;cnica de Valencia, Universidad de Valencia, Valencia, Spain; 2Departamento de Qu&iacute;mica, Universidad Polit&eacute;cnica de Valencia, Valenci…
Enzyme-Responsive Intracellular Controlled Release Using Nanometric Silica Mesoporous Supports Capped with "Saccharides"
2010
The synthesis of new capped silica mesoporous nanoparticles for on-command delivery applications is described. The gate-like functional hybrid systems consisted of nanoscopic MCM-41-based materials functionalized on the pore outlets with different “saccharide” derivatives and a dye contained in the mesopores. A series of hydrolyzed starch products as saccharides were selected. The mesoporous silica nanoparticles S1, S2, and S3 containing the grafted starch derivatives Glucidex 47, Gludicex 39, and Glucidex 29 were synthesized. Additionally, for comparative purposes solid S4 containing lactose was prepared. Delivery studies in pure water in the presence of pancreatin or -D-galactosidase were…
A lab in the field: applications of real-time, in situ metagenomic sequencing
2020
High-throughput metagenomic sequencing is considered one of the main technologies fostering the development of microbial ecology. Widely used second-generation sequencers have enabled the analysis of extremely diverse microbial communities, the discovery of novel gene functions, and the comprehension of the metabolic interconnections established among microbial consortia. However, the high cost of the sequencers and the complexity of library preparation and sequencing protocols still hamper the application of metagenomic sequencing in a vast range of real-life applications. In this context, the emergence of portable, third-generation sequencers is becoming a popular alternative for the rapi…
In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model.
2015
Our aim is to develop and to validate the in situ closed loop perfusion method in rat colon and to compare with small intestine and Caco-2 cell models. Correlations with human oral fraction absorbed (Fa) and human colon fraction absorbed (Fa_colon) were developed to check the applicability of the rat colon model for controlled release (CR) drug screening. Sixteen model drugs were selected and their permeabilities assessed in rat small intestine and colon, and in Caco-2 monolayers. Correlations between colon/intestine/Caco-2 permeabilities versus human Fa and human Fa_colon have been explored to check model predictability and to apply a BCS approach in order to propose a cut off value for CR…