Search results for "Predictive value"
showing 10 items of 927 documents
Distribution, function and predictive value of tumor-infiltrating γδ T lymphocytes
2013
Although γδ T cells are known to exert both tumor-preventing and tumor-promoting activity, there is still little information on the functional characteristics and clinical significance of γδ T cells isolated from the tumor site. In a recent study, we have investigated the distribution of different γδ T-cell populations in melanoma and their impact on disease outcome.
Predictive value of the Merrill-Palmer-R Scale applied during the first year of live
2016
Resumen basado en el de la publicación Títulos, resumen y palabras clave en inglés y español El valor predictivo de una escala de desarrollo utilizado durante el primer año de vida es de gran interés en la planificación de las intervenciones tempranas. El valor predictivo de un instrumento es la probabilidad de acertar el diagnóstico de trastorno o retraso en el desarrollo de un niño. Se analizaron las puntuaciones de escala Merrill-Palmer-R (MP-R) en una muestra de 291 niños menores de un año de la Comunidad Valenciana. A pesar de que no se distribuyen normalmente las puntuaciones de la escala MP-R en esta muestra, los resultados predichos eran buenos. Además, las puntuaciones de desarroll…
Predicting bullying: maladjustment, social skills and popularity
2012
In order to prevent bullying, research has characterised the adolescents involved in terms of their social skills, maladjustment and popularity. However, there is a lack of knowledge concerning the relationships between these variables and how these relationships predict bullying involvement. Moreover, the literature has focused on pure bullies and victims, despite the fact that bully-victims are known to be the most troubled. The aim of this work is to study the relationships between these variables and their predictive value, focusing on the bully-victim role. The sample (N = 641) is made up of adolescents aged between 12 and 17 years. The results mainly indicate that the level of maladju…
Prognostic significance of surrogate measures for forced vital capacity in an elderly population.
2009
Objectives To evaluate whether measures easier to obtain than the FVC can substitute it as a prognostic marker in elderly people. Design Prospective, observational study. Setting Community. Participants Outpatients (n = 1485) aged 73.4 years (SD: 6.2 range 65–98) enrolled in the Salute Respiratoria nell'Anziano (SaRA) study. Measurements We calculated the risk for mortality associated with a reduction below 80% of the predicted FVC, of the forced expiratory volume at 6 seconds (FEV6), and of a surrogate measure for forced vital capacity (SFVC), defined as the largest volume exhaled in 2 forced maneuvers regardless of its duration and of the presence of plateau. Results Among the 907 partici…
Prognostic value of FEV1/FEV6 in elderly people*
2010
Summary Background: The ratio of forced expiratory volume in 1 s and forced expiratory volume in 6 s (FEV1/FEV6) has been proposed as an alternative for FEV1/forced vital capacity (FVC) to diagnose obstructive diseases with less effort during spirometry; however, its prognostic value is unknown. We evaluated whether FEV1/FEV6 is a significant predictor of mortality in elderly subjects and compared its prognostic value with that of FEV1/FVC and FEV1. Methods: One thousand nine hundred and seventy-one subjects, aged >65 years, participated in the population-based SA.R.A. study. During the baseline exam, a multidimensional assessment included spirometry. Vital status was determined during 6 …
Use of Logistic Regression for Prediction of the Fate of Staphylococcus aureus in Pasteurized Milk in the Presence of Two Lytic Phages
2010
The use of bacteriophages provides an attractive approach to the fight against food-borne pathogenic bacteria, since they can be found in different environments and are unable to infect humans, both characteristics of which support their use as biocontrol agents. Two lytic bacteriophages, vB_SauS-phiIPLA35 (phiIPLA35) and vB_SauS-phiIPLA88 (phiIPLA88), previously isolated from the dairy environment inhibited the growth of Staphylococcus aureus. To facilitate the successful application of both bacteriophages as biocontrol agents, probabilistic models for predicting S. aureus inactivation by the phages in pasteurized milk were developed. A linear logistic regression procedure was used to desc…
Vergleich der prognostischen Aussagefähigkeit der Catterall- und Herring-Klassifikation bei Patienten mit Morbus Perthes
2008
QUESTION Investigation of the predictive value of the Catterall- as compared to the Herring-classification in patients with Perthes disease. METHOD A radiological follow-up study including 53 patients with a total of 59 affected hips was carried out. In the initial diagnosis the Catterall-, Waldenstrom- and Herring-stages were assessed. The epiphyseal ratio, the head-neck ratio and the lateral subluxation were measured and compared at the time of diagnosis, fragmentation stage and in a follow-up examination, which was carried out 4, 9 years after diagnosis on the average. The results of the follow-up examination were assessed using the Mose-classification and compared as well. In addition t…
Intraductal aspiration: a promising new tissue-sampling technique for the diagnosis of suspected malignant biliary strictures
2012
Brushing is the most commonly used technique for biliary sampling at ERCP, despite its limited sensitivity. To evaluate intraductal aspiration (IDA) as a new combined endoscopic technique for cytodiagnosis, its cellular adequacy, diagnostic accuracy for cancer detection, feasibility, and safety. Prospective, observational study. Single tertiary referral center. IDA cellular adequacy, diagnostic accuracy for cancer detection, feasibility, and safety. From April 2009 to September 2010, 42 consecutive patients with suspected malignant biliary stricture underwent ERCP, with tissue sampling obtained with IDA. IDA included performance of standard brushing in all patients. After standard brushing,…
Polymorphism of the transcription factor 7-like 2 gene (TCF7L2) interacts with obesity on type-2 diabetes in the PREDIMED study emphasizing the heter…
2016
Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover, TCF7L2-rs7903146 is one of the most influential variants in T2D-genetic risk scores (GRS). Therefore, to increase the predictive value (PV) of GRS it is necessary to first see whether the included polymorphisms have heterogeneous effects. We comprehensively investigated gene-obesity interactions between the TCF7L2-rs7903146 C > T polymorphism on T2D (prevalence and incidence) and analyzed other T2D-polymorphisms in a sub-sample. We studied 7018 PREDIMED …