Search results for "Predimed"

showing 10 items of 103 documents

Plasma lipidomic profiles and cardiovascular events in a randomized intervention trial with the Mediterranean diet.

2017

Background: Lipid metabolites may partially explain the inverse association between the Mediterranean diet (MedDiet) and cardiovascular disease (CVD).Objective: We evaluated the associations between 1) lipid species and the risk of CVD (myocardial infarction, stroke, or cardiovascular death); 2) a MedDiet intervention [supplemented with extra virgin olive oil (EVOO) or nuts] and 1-y changes in these molecules; and 3) 1-y changes in lipid species and subsequent CVD.Design: With the use of a case-cohort design, we profiled 202 lipid species at baseline and after 1 y of intervention in the PREDIMED (PREvencion con DIeta MEDiterranea) trial in 983 participants [230 cases and a random subcohort …

PREDIMEDMalemedicine.medical_specialtyMediterranean dietMedicine (miscellaneous)030209 endocrinology & metabolism030204 cardiovascular system & hematologyDiet Mediterraneanlaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRandomized controlled triallawcardiovascular diseaseRisk FactorsInternal medicineMediterranean dietmedicinerandomized trialHumansNutsMyocardial infarctionStrokeOlive OilAgedNutrition and Dieteticsbusiness.industryCholesterolLipid metabolismCardiovascular Disease RiskLipidomeMiddle Agedmedicine.diseaseLipid MetabolismPredimedmetabolomicsDietary FatsLipidsEndocrinologychemistryCardiovascular DiseasesDietary SupplementsFemaleCholesterol Estersbusiness
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Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study

2020

Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other global lifestyle indices, and none in aged populations at high cardiovascular risk. We aimed to assess the association between CRC incidence and adherence to two emerging lifestyles indices (2018 WCRF/AICR score and another low-risk lifestyle (LRL) score comprising smoking status, alcohol consumption, physical activity, diet, and body mass index) in the Spanish PREvencion con DIeta MEDiterranea (PREDIMED) cohort. We studied 7216 elderly men and women at high cardiovascul…

PREDIMEDmedicine.medical_specialtyEstils de vidaColorectal cancerWCRF/AICR scoreLifestyleslcsh:Medicinecolorectal cancerArticle03 medical and health sciences0302 clinical medicineInterquartile rangeCàncer colorectalInternal medicinemedicinelifestyle patterns030212 general & internal medicineAICR scorebusiness.industryIncidence (epidemiology)Hazard ratiolcsh:RGeneral Medicinemedicine.diseasePredimedConfidence intervalWCRFlow-risk lifestyle index030220 oncology & carcinogenesisCohortbusinessBody mass indexJournal of Clinical Medicine
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Carbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trial.

2020

[Background]: Overall quality of dietary carbohydrate intake rather than total carbohydrate intake may determine the risk of cardiovascular disease (CVD).

PREDIMED-Plus carbohydrate carbohydrate quality index cardiovascular disease fiber glycemic index obesity randomized controlled trialsMaleobesity030309 nutrition & dieteticsMedicine (miscellaneous)030204 cardiovascular system & hematologyOverweightchemistry.chemical_compound0302 clinical medicinecardiovascular diseaseRisk FactorsSurveys and QuestionnairesGlycemic indexLongitudinal StudiesProspective Studies2. Zero hunger0303 health sciencesNutrition and DieteticsMiddle AgedCardiovascular disease3. Good healthGlycemic indexCardiovascular Diseasesrandomized controlled trialsRandomized controlled trialsFemalemedicine.symptomfibermedicine.medical_specialtyWaistCarbohydrates03 medical and health sciencesInternal medicinemedicineDietary CarbohydratesHumansFiberObesityAgedCarbohydrate quality indexTriglyceridebusiness.industryPREDIMED-PlusOverweightmedicine.diseaseObesityDietBlood pressurechemistrycarbohydratecarbohydrate quality indexglycemic indexGlycated hemoglobinMetabolic syndromebusinessEnergy Intake
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Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome.

2019

The authors especially thank the PREDIMED-Plus participants for their enthusiastic collaboration, the PREDIMED-Plus personnel for their outstanding support, and the personnel of all associated primary care centers for their exceptional effort. Centros de Investigación Biomédica en Red: Obesidad y Nutrición (CIBEROBN), Centros de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP) and Centros de Investigación Biomédica en Red: Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM) are initiatives of Instituto de Salud Carlos III (ISCIII), Madrid, Spain. We thank the PREDIMED-Plus Biobank Network, part of the National Biobank Platform of ISCIII for storing and managing …

Síndrome metabòlicaWaistlcsh:MedicineDietética y nutrición030209 endocrinology & metabolismbody mass indexType 2 diabetesOverweightArticleDiabetis no-insulinodependent03 medical and health sciencesnap0302 clinical medicinemental disordersEndocrinologíaMedicineNon-insulin-dependent diabetes2. Zero hungerbusiness.industrylcsh:Rfunginutritional and metabolic diseasesActigraphyPREDIMED-Plus studyPREDIMED-PlusGeneral Medicinemedicine.diseasewaist circumferenceObesityMetabolic syndrome3. Good healthNapPREDIMED-Plus actigraphy body mass index nap type 2 diabetes waist circumferencetype 2 diabetesmedicine.symptomMetabolic syndromebusinessBody mass indexhuman activities030217 neurology & neurosurgerypsychological phenomena and processesDemographyactigraphy
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Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elde…

2021

The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research grant 2014–2019; agreement #340918; granted to M.Á.M.-G.); the official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS) which is co-funded by the European Regional Development Fund (coordinated FIS projects led by J.S-S. and J.V., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI…

Síndrome metabólicoMaleFood processingMediterranean dietNOVAObesidadÍndice de masa corporal:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineultra-processed foodMedicineTX341-641:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight [Medical Subject Headings]Body mass indexclassification systemsIncidenceIARC:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]Metabolic syndrome3. Good healthNutriciónCohortManipulación de alimentosDietaFactores de riesgo cardiometabólicoConcordanceUNC:Check Tags::Male [Medical Subject Headings]ClasificaciónClassification systemsDiet SurveysArticle03 medical and health sciencesfood processingHumans:Diseases::Cardiovascular Diseases [Medical Subject Headings]Aged030109 nutrition & dietetics:Health Care::Health Care Economics and Organizations::Organizations::International Agencies [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesity:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Blood pressure:Check Tags::Female [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Linear ModelsFast FoodsMetabolic syndromeOlder people0301 basic medicineSíndrome metabòlicaFood HandlingOverweightDiet MediterraneanPersones gransCohort Studiescardiometabolic riskEndocrinología030212 general & internal medicine:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerMetabolic SyndromeNutrition and Dietetics:Technology and Food and Beverages::Technology Industry and Agriculture::Industry::Food Industry::Food Handling [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Nutrition Surveys::Diet Surveys [Medical Subject Headings]Female:Technology and Food and Beverages::Food and Beverages::Food::Fast Foods [Medical Subject Headings]medicine.symptom:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome X [Medical Subject Headings]Dietética y nutrición:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings]Environmental healthMediterranean dietObesityAlimentos ultraprocesados:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]NutricióNutrition:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryNutrition. Foods and food supplyCardiometabolic Risk FactorsOverweightDieta mediterráneaCardiometabolic riskUltra-processed foodDietSpainIFICSobrepesoFood processingbusinessdietFood ScienceNutrients
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Polymorphism of the transcription factor 7-like 2 gene (TCF7L2) interacts with obesity on type-2 diabetes in the PREDIMED study emphasizing the heter…

2016

Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover, TCF7L2-rs7903146 is one of the most influential variants in T2D-genetic risk scores (GRS). Therefore, to increase the predictive value (PV) of GRS it is necessary to first see whether the included polymorphisms have heterogeneous effects. We comprehensively investigated gene-obesity interactions between the TCF7L2-rs7903146 C > T polymorphism on T2D (prevalence and incidence) and analyzed other T2D-polymorphisms in a sub-sample. We studied 7018 PREDIMED …

TCF7L2endocrine system:Ciencias de la Salud::Salud pública [Materias Investigacion]endocrine system diseasesnutritional and metabolic diseasesTCF7L2-predictive valuePREDIMED studyObesityT2D-genetic risk scoresType-2 diabetes
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Taste Perception Profiles and Adiposity in Older Adults with Metabolic Syndrome – PREDIMED-Plus

2020

OBJECTIVES: In humans, perception for each taste (sweet, salt, sour, bitter and umami) has been independently related to food preferences and intake. Yet, the collective influence of perception of all 5 tastes on diet and cardiometabolic health remains unexplored. Therefore, our objective was to investigate the relations between a collective measure of taste perception – “taste perception profiles” – and adiposity. METHODS: We analyzed baseline data of 367 older adults (55–75 years; 55% female) with metabolic syndrome (MetS) participating in the PREDIMED-Plus Valencia trial. Taste perception was assessed for sweet, salt, sour, bitter and umami using sucrose, NaCl, citric acid, phenylthiocar…

Tastemedicine.medical_specialtyNutrition and Dieteticsbusiness.industrymedia_common.quotation_subjectPhysical activityMedicine (miscellaneous)medicine.diseasePredimedDrug usageObesityEndocrinologystomatognathic systemDiabetes mellitusPerceptionInternal medicinemedicineObesityMetabolic syndromebusinesspsychological phenomena and processesFood Sciencemedia_common
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Efectos de la dieta Mediterránea y de sus principales componentes en la morbi-mortalidad por cáncer y su modulación genética en el estudio PREDIMED

2017

El cáncer es el nombre común que recibe un conjunto de enfermedades relacionadas en las que se existe un proceso descontrolado en el crecimiento de las células del cuerpo, causado por anormalidades en el material genético de las células. La carcinogénesis o proceso por el cual se produce el cáncer, se debe a múltiples agentes carcinógenos como virus, radiaciones, sustancias químicas, factores del estilo de vida como el consumo de tabaco, alcohol, o tipo de alimentación, entre otros agentes. La dieta mediterránea es el modo de alimentarse basado en los patrones dietéticos de los países mediterráneos y se caracteriza por un alto consumo de productos vegetales (frutas, verduras, legumbres, pan…

UNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::Genética clínica:CIENCIAS MÉDICAS ::Ciencias de la Nutrición ::Otras [UNESCO]dieta mediterránea:CIENCIAS MÉDICAS ::Ciencias clínicas::Oncología [UNESCO]:CIENCIAS MÉDICAS ::Ciencias clínicas::Genética clínica [UNESCO]genética:CIENCIAS MÉDICAS ::Medicina preventiva [UNESCO]UNESCO::CIENCIAS MÉDICAS ::Medicina preventivaestudio predimedUNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::OncologíaUNESCO::CIENCIAS MÉDICAS ::Salud públicaUNESCO::CIENCIAS MÉDICAS ::Ciencias de la Nutrición ::Otrascáncer:CIENCIAS MÉDICAS ::Salud pública [UNESCO]
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IS COMPLYING WITH THE RECOMMENDATIONS OF SODIUM INTAKE BENEFICIAL FOR HEALTH? EVIDENCE FROM THE PREDIMED STUDY

2014

business.industryEnvironmental healthMedicineCardiology and Cardiovascular MedicinebusinessPredimedSodium intake
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Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial

2021

The increased prevalence of atrial fibrillation (AF) and heart failure (HF) highlights the need to better understand the mechanisms underlying these cardiovascular diseases (CVDs). In the present study, we aimed to evaluate the association between glycolysis-related metabolites and the risk of AF and HF in a Mediterranean population at high risk of CVD. We used two case-control studies nested within the PREDIMED trial. A total of 512 incident AF cases matched to 734 controls, and 334 incident HF cases matched to 508 controls, were included. Plasma metabolites were quantified by using hydrophilic interaction liquid chromatography coupled with high-resolution negative ion mode MS detection. C…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismPopulationheart failureHeart failure030204 cardiovascular system & hematologyBiochemistryMicrobiologyPathogenesis03 medical and health sciences0302 clinical medicineInternal medicinemedicineGlycolysisatrial fibrillation030212 general & internal medicineeducationMolecular Biologyeducation.field_of_studybusiness.industryBrief ReportAtrial fibrillationPREDIMED studyglycolysismedicine.diseasePredimedAtrial fibrillationQR1-502Increased riskHeart failureCardiologyConditional logistic regressionbusinessGlycolysis
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