Search results for "Pregnancy."

showing 10 items of 1965 documents

Rat CNS neurons are not yet programmed to shorten their chromatin repeat length at the end of fetal neurogenesis.

1986

Neurons from rat fetal cerebral hemispheres were grown in a synthetic medium (Maat medium), as previously described, for different periods of time. The repeat length of their chromatin was determined by micrococcal nuclease digestion and compared with that of neurons isolated from postnatal rat brain of corresponding ages. In contrast to the in vivo situation, we found that neurons, dissociated at the 16th gestational day and cultured in vitro, did not undergo the shortening of their chromatin repeat, thus indicating that, at the end of their mitotic cycles, they are not yet programmed to this event. © 1986.

Settore MED/07 - Microbiologia E Microbiologia ClinicaAgingCellular differentiationCentral nervous systemGestational AgeFetusPregnancymedicineAnimalsMitosisCells CulturedCell NucleusNeuronsFetusbiologyNeurogenesisBrainCell DifferentiationdifferentiationCell BiologyDNAneuronChromatinChromatinCell biologyRatsMolecular Weightmedicine.anatomical_structureSettore BIO/12 - Biochimica Clinica E Biologia Molecolare ClinicaImmunologybiology.proteinSettore MED/26 - NeurologiaFemaleNeuronMicrococcal nucleaseCell biology international reports
researchProduct

Consensus On Women'S Health Aspects Of Polycystic Ovary Syndrome (Pcos)

2012

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females with a high prevalence. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. Two, widely cited, previous ESHRE/ASRM-sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008). The present third PCOS consensus paper summarizes current knowledge and identifies knowledge gaps regarding various women's health aspects of PCOS. Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, preg…

Settore MED/09 - Medicina InternaConsensus Development Conferences as TopicmenopauseType 2 diabetesSettore MED/13 - EndocrinologiaQuality of lifecancer; cardiovascular disease; contraception; hirsutism; insulin resistance; menopause; PCOS; pregnancy; quality of life; type 2 diabetescardiovascular diseaseNeoplasmsinsulin resistancePCOShirsutismhirsutismReproductive BiologyPolycystic ovary syndrome (PCOS)RehabilitationObstetrics and GynecologyObstetrics & GynecologyMiddle AgedMenopausePhenotypecontraceptionCardiovascular DiseasesPCOS Cardiovascular risk adolescence cancer obesityFemalepregnancytype 2 diabetesPolycystic Ovary SyndromeAdultmedicine.medical_specialtyConsensusAdolescentDiabetes ComplicationsInsulin resistanceSDG 3 - Good Health and Well-beingmedicineHumanscancerMenstrual CycleAgedGynecologyPregnancybusiness.industryCancermedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaReproductive MedicineDiabetes Mellitus Type 2quality of lifeWomen's Healthbusiness
researchProduct

Osteoporosis in pregnancy: A case report and review of the literature

2014

Settore MED/09 - Medicina InternaOsteoporosis; pregnancyOsteoporosipregnancy
researchProduct

Inflammatory Bowel Disease (IBD) in pregnancy: analysis of the possible effects of the disease on the fetus and the newborn and therapeutic approaches

2015

The Inflammatory Bowel Diseases(IBD), are a group of inflammatory diseases characterized by the presence of chronic inflammation, i the absenc of infectious ethiology. The two most well-known diseases in this group are: Crohn's disease (CD) and Ulcerative Colitis (UC). In cases where iti is not possible to distinguish between CD and UC, it is called Indeterminated Colitis. IBD can affect women pregnant. The causes of IBD are unknown, and the clinical course of the sdisease is characterized by phases of activity and remission. UC is a chronic inflammation of the mucosa of the colon and involving predominantly the left colon and rectum. It is associatred with presence of blood and mucus in th…

Settore MED/18 - Chirurgia GeneraleSettore MED/09 - Medicina InternaIBD Inflammatory Bowel Diseases IBD in PregnancySettore MED/40 - Ginecologia E Ostetricia
researchProduct

MULTIPLE PREGNANCY NEWBORN BABIES

2009

Settore MED/38 - Pediatria Generale E SpecialisticaReproductive Techniques AssistedPregnancyInfant NewbornHumansFemalePregnancy MultipleInfant Newborn DiseasesTWIN NEWBORNS
researchProduct

Female age at first pregnancy and work task: finding correlation and evolution over the past two decades in a Sicilian province

2015

Background: the entrance of women in the workforce, due to a their growing cultural and, accordingly, social commitment, changed many aspects of their lives; the research or the maintenance of a job, especially during periods of severe economic crisis, leads to a delay of many physiological stage, maternity at first. The aim of this study is to verify and, if it really happened, to quantify an increasing age of first-time mothers in a sample of mothers in the province of Agrigento in the last 20 years, correlating any positive response to the work task performed. Material and Methods: we have enrolled all primiparous women who gave birth in a hospital in the province of Agrigento, from Janu…

Settore MED/44 - Medicina Del Lavoroaging first pregnancy infant occupation unemployed
researchProduct

Two Patients With History of STEC-HUS, Posttransplant Recurrence and Complement Gene Mutations

2013

Hemolytic uremic syndrome (HUS) is a disease of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. About 90% of cases are secondary to infections by Escherichia coli strains producing Shiga-like toxins (STEC-HUS), while 10% are associated with mutations in genes encoding proteins of complement system (aHUS). We describe two patients with a clinical history of STEC-HUS, who developed end-stage renal disease (ESRD) soon after disease onset. They received a kidney transplant but lost the graft for HUS recurrence, a complication more commonly observed in aHUS. Before planning a second renal transplantation, the two patients underwent genetic screening for aHUS-associat…

Shiga-toxinGraft RejectionMaleDNA Primer030232 urology & nephrologyEscherichia coli InfectionGene mutationurologic and male genital diseasesGastroenterology0302 clinical medicineRecurrenceRisk Factorshemic and lymphatic diseasesImmunology and AllergyPharmacology (medical)gene mutationKidney transplantationEscherichia coli Infections0303 health sciencesKidneymedicine.diagnostic_testShiga-Toxigenic Escherichia coliAntigens CD46Microangiopathic hemolytic anemiaMiddle AgedPrognosisfemale genital diseases and pregnancy complications3. Good healthPedigreemedicine.anatomical_structureComplement Factor IComplement factor I; gene mutation; hemolytic uremic syndrome; kidney transplantation; membrane cofactor protein; Shiga-toxin; Adult; Antigens CD46; Case-Control Studies; Complement Factor I; DNA Primers; Escherichia coli Infections; Female; Genetic Testing; Graft Rejection; Hemolytic-Uremic Syndrome; Heterozygote; Humans; Kidney Failure Chronic; Kidney Transplantation; Male; Middle Aged; Mutation; Pedigree; Prognosis; Recurrence; Risk Factors; Shiga-Toxigenic Escherichia coli; Thrombocytopenia; Young Adult; Transplantation; Immunology and Allergy; Pharmacology (medical)FemaleCase-Control StudieHumanAdultmedicine.medical_specialtyHeterozygotePrognosiComplement factor IMembrane Cofactor Protein03 medical and health sciencesYoung AdultInternal medicinemedicineHumansGenetic Testing030304 developmental biologyGenetic testingDNA PrimersTransplantationbusiness.industryCD46Risk Factormedicine.diseaseKidney TransplantationThrombocytopeniaTransplantationCase-Control StudiesImmunologyHemolytic-Uremic SyndromeMutationhemolytic uremic syndromeKidney Failure ChronicbusinessAmerican Journal of Transplantation
researchProduct

Extracorporeal Shock Wave Lithotripsy of Ureteral Stones: Clinical Experience and Experimental Findings

1986

AbstractESWL of impacted ureteral or caliceal stones is not as successful as expected. To study this problem a model for extracorporeal shock wave lithotripsy of ureteral stones has been designed. After initial fragmentation of the outer shell of impacted stones during the first series of shock wave application those fragments are kept in place by external mucosal contact, creating a lot of new interfaces.Absorption or reflection of shock wave energy within this fragmented shell seems to be responsible for the poor success rate in these cases. In regard to our experimental and clinical results we advise pushing ureteral stones back into the renal collecting system by means of a ureteral cat…

Shock wavemedicine.medical_specialtyUreteral Calculiurogenital systembusiness.industryUrologymedicine.medical_treatmentIn Vitro Techniquesurologic and male genital diseasesCollection systemExtracorporeal shock wave lithotripsyfemale genital diseases and pregnancy complicationsSurgeryModels StructuralKidney CalculiLithotripsymedicineHumansbusinessUrethral catheterJournal of Urology
researchProduct

Occiput-spine relationship: shoulders are more important than head.

2017

BACKGROUND:To understand the role of fetal spine position in determining a fetal head position at the time of birth and modality of delivery. PATIENTS AND METHODS: This was a multicenter prospective observational study. Fetal occiput and spine position were evaluated by intrapartum ultrasound. Eighty-six women were eligible for inclusion in the study. Occiput rotational movements and modality of delivery in relation to the fetal spine position were investigated. RESULTS: At the beginning of labor, fetal occiput was in a posterior position in 52.3% of cases and, in 81.5% of cases the spine was in an anterior transverse position. At birth, occiput and spine were both in an anterior position i…

Shoulders head occipit-spine relationshipShoulderOcciput-Spine RelationshipSocio-culturaleFetal spineObstetric labor Fetal spine Intrapartum ultra- sound Occiput posterior Occiput-Spine Relationship.SpineUltrasonography PrenatalLabor PresentationObstetric labor Fetal spine Intrapartum ultrasound Occiput posterior Occiput-Spine Relationship.Obstetric laborFetusPregnancyOcciput posteriorHumansFemaleProspective StudiesHeadIntrapartum ultra- soundEuropean review for medical and pharmacological sciences
researchProduct

Tetraspanin CD151 Mediates Papillomavirus Type 16 Endocytosis

2013

ABSTRACT Human papillomavirus type 16 (HPV16) is the primary etiologic agent for cervical cancer. The infectious entry of HPV16 into cells occurs via a so-far poorly characterized clathrin- and caveolin-independent endocytic pathway, which involves tetraspanin proteins and actin. In this study, we investigated the specific role of the tetraspanin CD151 in the early steps of HPV16 infection. We show that surface-bound HPV16 moves together with CD151 within the plane of the membrane before they cointernalize into endosomes. Depletion of endogenous CD151 did not affect binding of viral particles to cells but resulted in reduction of HPV16 endocytosis. HPV16 uptake is dependent on the C-termina…

Small interfering RNAEndosomevirusesmedia_common.quotation_subjectDNA Mutational AnalysisImmunologyEndocytic cycleIntegrinTetraspanin 24EndocytosisMicrobiologyClathrinCell LineTetraspaninVirologyHumansInternalizationmedia_commonHuman papillomavirus 16integumentary systembiologyvirus diseasesVirus InternalizationMolecular biologyEndocytosisfemale genital diseases and pregnancy complicationsVirus-Cell InteractionsCell biologyGene Knockdown TechniquesInsect Sciencebiology.proteinMutant ProteinsJournal of Virology
researchProduct