Search results for "Prenatal"

Prenatal exposure to organochlorine compounds and lung function during childhood

2019

Introduction: Prenatal exposure to organochlorine compounds (OCs) can increase the risk of reported respiratory symptoms in children. It remains unclear whether these compounds can also impact on lung function. We assessed the association between prenatal exposure to OCs and lung function during childhood. Methods: We included 1308 mother-child pairs enrolled in a prospective cohort study. Prenatal concentrations of p,p′-dichlorodiphenyltrichloroethane [p,p′-DDT], p,p′-dichlorodiphenyldichloroethylene [p,p′-DDE], hexachlorobenzene [HCB], and seven polychlorinated biphenyls [PCBs] were measured in cord blood. Spirometry was performed in the offspring at ages 4 (n = 636) and 7 years (n = 1192…

Prenatal exposure to perfluoroalkyl substances, immune-related outcomes, and lung function in children from a Spanish birth cohort study.

2019

Background: Prenatal exposure to perfluoroalkyl substances (PFASs) has been associated with impaired immune and respiratory health during childhood but the evidence is inconsistent and limited for lung function. We studied the association between prenatal PFASs exposure and immune and respiratory health, including lung function, up to age 7 years in the Spanish INMA birth cohort study. Methods: We assessed four PFASs in maternal plasma samples collected during the 1st trimester of pregnancy (years: 2003-2008): perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA). Mothers reported the occurrence (yes/no) of lower respir…

Relationships between early flavor exposure, and food acceptability and neophobia

2016

Revue; In the first section of this chapter, an overview of what is known about early flavor exposure, distinguishing between taste and flavor (aroma) exposure is provided. In the second section, we will describe what has been researched regarding the influence of early flavor exposure on the development of food preference, looking at prenatal exposure, exposure received in the context of milk feeding and exposure received in the context of complementary feeding. The third section is a description of what has been shown regarding the relationships between early flavor exposure and food neophobia. The chapter ended with a comment on likely future trends, and by a description of sources of fu…

Prenatal sonographic chest and lung measurements for predicting severe pulmonary hypoplasia.

1999

Pulmonary hypoplasia was diagnosed sonographically in 32 fetuses from 20 to 33 weeks of gestation. In addition to standard biometry, transverse thoracic diameter (TTD), sagittal thoracic diameter (TSD), thoracic circumference (TC) and lung diameter (LD) were measured in all cases and compared with known nomograms. The fetuses were divided into five groups according to the main sonographic findings: group 1—skeletal dysplasia; group 2—renal agenesis; group 3—diaphragmatic hernia; group 4—hydrothorax; and group 5—others. Severe pulmonary hypoplasia (PH) was diagnosed prenatally in all cases on the basis of LD measurements. In 17 (53.1 per cent) out of 32 cases TTD was below the 5th percentile…

Volume scanning in the evaluation of fetal malformations: a new dimension in prenatal diagnosis

1995

Three-dimensional ultrasound examination was performed in 204 patients with a fetal malformation detected by conventional ultrasound. The patients were examined between 13 and 40 weeks of gestation. The ultrasound equipment used was a Combison 330 and a Combison 530 (Kretztechnik, Austria) with an abdominal Voluson sector transducer (3.5/5 MHz) (Kretztechnik, Austria). This ultrasound system can provide a high-quality three-dimensional surface or translucency image of fetal structures similar to that of a photograph or an X-ray image within seconds without an additional expensive work-station. Of the 204 patients examined with three-dimensional ultrasound, this technique proved advantageous…

Three Dimensional ultrasound - a requirement for prenatal diagnosis?

1998

Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe : impact of maternal age and prenatal screening

2013

This study examines trends and geographical differences in total and live birth prevalence of trisomies 21, 18 and 13 with regard to increasing maternal age and prenatal diagnosis in Europe. Twenty-one population-based EUROCAT registries covering 6.1 million births between 1990 and 2009 participated. Trisomy cases included live births, fetal deaths from 20 weeks gestational age and terminations of pregnancy for fetal anomaly. We present correction to 20 weeks gestational age (ie, correcting early terminations for the probability of fetal survival to 20 weeks) to allow for artefactual screening-related differences in total prevalence. Poisson regression was used. The proportion of births in …

Influencia de las técnicas de reproducción asistida en el cribado de aneuploidías de las 11-13 semanas

2014

Los marcadores bioquímicos (PAPP-A y β-hCG) del cribado del primer trimestre del síndrome de Down se ven afectadas por múltiples variables (tabaco, raza, edad gestacional, peso) por lo que requieren un ajuste. Previos estudios han observado diferencias en estos marcadores en gestaciones obtenidas mediante técnicas de reproducción asistida (TRA); sin embargo los datos existentes hasta ahora son inconcluyentes. El cribado del síndrome de Down en el grupo de mujeres gestantes mediante TRA es más complicado que en el grupo de gestantes que conciben de manera natural por varios motivos. Entre ellos se encuentra el hecho de que la proporción de gestantes con 35 años o más en este grupo es mayor, …

New Insights into the Anterior Complex

2020

<b><i>Objective:</i></b> To introduce visualization of the germinal matrix (GM), external angle of the frontal horn, and periventricular white matter while evaluating the anterior complex (AC) during basic ultrasound assessment of the fetal brain. <b><i>Case Presentations:</i></b> This is a retrospective observational study of healthy women with singleton pregnancies, with no increased risk of fetal central nervous system anomalies, attending routine ultrasound screening at 20–32 weeks’ gestation. Seventeen cases are presented in which an abnormal aspect of the GM or external angle of the frontal horn or periventricular white matter on AC eval…

A combination of umbilical artery PI and normalized blood flow volume in the umbilical vein: Venous–arterial index for the prediction of fetal outcome

2008

Abstract Objective The objective was to assess the diagnostic power of the umbilical venous–arterial index (VAI) as a combination of the pulsatility index in the umbilical artery and the normalized blood flow volume in the umbilical vein for the prediction of poor fetal outcome. Study design This was a prospective clinical study in which the umbilical artery PI (UAPI), the normalized umbilical vein blood volume flow rate ( n UV; ml/min/kg estimated fetal body weight), the venous–arterial index (VAI; n UV/UAPI), and the pulsatility index (PI) in the umbilical artery (UA), uterine artery (utA), middle cerebral artery (MCA), and aorta were determined in 181 fetuses once (at between 17 and 41 w…