Search results for "Presentation"

Synaptic Scaling Enables Dynamically Distinct Short- and Long-Term Memory Formation

2013

Memory storage in the brain relies on mechanisms acting on time scales from minutes, for long-term synaptic potentiation, to days, for memory consolidation. During such processes, neural circuits distinguish synapses relevant for forming a long-term storage, which are consolidated, from synapses of short-term storage, which fade. How time scale integration and synaptic differentiation is simultaneously achieved remains unclear. Here we show that synaptic scaling – a slow process usually associated with the maintenance of activity homeostasis – combined with synaptic plasticity may simultaneously achieve both, thereby providing a natural separation of short- from long-term storage. The inter…

The content validity of the adult attachment interview. An empirical investigation using text analysis

2011

The aim of this study was to conduct a preliminary investigation of the content validity of the Adult Attachment Interview (AAI). Content validity is a series of hypothesis control methods relating to the communication of facts and it can be tested using several procedures of analytical decomposition (Rositi, 1988). In order to evaluate the content validity of a text, Sireci (1998), Sireci and Geisinger (1992, 1995), and Ding (2005) suggested the integration within this technique of multidimensional scaling and cluster analysis. The aim of this study was to conduct a preliminary investigation of the content validity of the AAI, as proposed in the literature. We hypothesized that participant…

Aesthetics of Geometry and the Problem of Representation in Monument Sculpture

2017

Since the 1920s and 1930s, constructivist and concretist visual art movements have stressed geometric forms, proportions and orders as a base for artistic expressions and aesthetic experiences. After the World War II geometric form was adopted to the public sculpture. Abstract, geometrically constructed sculpture was also used in commemorative functions in modern monument art. The combination of the commemoration of a significant historical event or a national hero, and the aesthetic ideas based on constructivist or concretist art movements caused a lot of debates and confrontations in many Western countries. In particular, the interpretation of abstract monuments problematized: abstract mo…

Henstock type integral in compact zero-dimensional metric space and quasi-measures representations

2012

Properties of a Henstock type integral defined on a compact zero-dimensional metric space are studied. Theorems on integral representation of so-called quasi-measures, i.e., linear functionals on the space of “polynomials” defined on the space of the above mentioned type, are obtained.

Il rilievo e la rappresentazione dell’architettura storica per la progettazione del restauro: il caso dello Stand Florio a Palermo

2010

I grafici sono un esempio di rilevamento metrico e rappresentazione dell'architettura che sono specifici per la progettazione del restauro. Il caso che viene presentato è lo studio dello stand Florio a Palermo. The graphics are an example of metric survey and representation of architecture that are specific to the restoration project. The presented case study is the Florio Stand in Palermo.

Mexican Americans in the New York Times : a study of proposition 187 in California

2002

Gender in translating lesbianism in The Second Sex

2011

Drawing on three Chinese translations of the lesbian chapter in Simone de Beauvoir’s The Second Sex, this paper examines at the micro level how the discussions on lesbianism in the work are translated and what role gender identity plays in the process of translation. Lesbianism has played an important part in feminism. However, homosexuality is still regarded as unacceptable to most Chinese people. Thus, an examination of translations of lesbianism in The Second Sex might be especially revealing in terms of representation of Western feminism. The comparison reveals that there are obvious differences between the translations by the female translators and the male translators. The differences…

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection

2021

Murine models of cytomegalovirus (CMV) infection have revealed an immunological phenomenon known as “memory inflation” (MI). After a peak of a primary CD8+ T-cell response, the pool of epitope-specific cells contracts in parallel to the resolution of productive infection and the establishment of a latent infection, referred to as “latency.” CMV latency is associated with an increase in the number of cells specific for certain viral epitopes over time. The inflationary subset was identified as effector-memory T cells (iTEM) characterized by the cell surface phenotype KLRG1+CD127−CD62L−. As we have shown recently, latent viral genomes are not transcriptionally silent. Rather, viral genes are …

Modulation of accessory cell function of immortalized bone marrow-derived macrophages by granulocyte/macrophage colony-stimulating factor.

1993

To generate cloned macrophage populations with sensitivity towards granulocyte/macrophage colony-stimulating factor (GM-CSF), bone marrow-derived macrophages (BMM phi) were immortalized by transformation with SV40. A panel of transformed clones was established. The majority of clones represented independently derived transformants, as evidenced by restriction fragment length polymorphism using genomic DNA digested with EcoRI and TaqI and the 5.2 kb SV40 DNA for hybridization analysis. The cells belong to the macrophage lineage according to several criteria, e.g. the presence of nonspecific esterase, their phagocytic capacity and their morphology. Many clones were potent antigen-presenting c…

Proliferation and MHC-unrestricted bystander lysis by virus-specific cytotoxic T cells following antigen self-presentation.

1998

Cytotoxic T cells (CTL) not only act as effector cells, but can also serve as antigen-presenting cells (APC) for other CTL due to their expression of major histocompatibility complex (MHC) class I molecules. In the present study we show that independently derived CTL lines (CTLL) with specificity for an L(d)-presented nonapeptide corresponding to amino acids 168-176 of the immediate-early 1 (IE1) protein of murine cytomegalovirus not only lyse syngeneic but also allogeneic target cells, if the peptide is present during the cytolytic assay. Whereas a short peptide pulse is sufficient to render syngeneic cells susceptible to lysis, continued presence of soluble peptide is mandatory for the ly…