Search results for "Presentation"

Major histocompatibility complex class II binding site for streptococcal pyrogenic (erythrogenic) toxin A.

1994

Streptococcal pyrogenic exotoxin A (SPEA) is an important pathogenicity factor of group A streptococci. It is a member of the family of „superantigens” produced by Staphylococcus aureus and Streptococcus pyogenes and its T lymphocyte stimulating activity is involved into the pathogenesis of certain diseases caused by pyogenic streptococci. In this study we have produced and characterized recombinant SPEA molecules in Escherichia coli. These molecules are indistinguishable from natural SPEA in both T cell stimulatory and HLA class II binding activities. Human class II molecules are more efficient than mouse class II molecules in presenting SPEA to T cells. In binding tests to major histocomp…

Governance and Scope Economies in Microfinance Institutions

2013

This paper studies the relation between board size and composition and cost savings (scope economies) from combining savings mobilization and lending by Microfinance Institutions. The findings support the hypothesis that employee representation on the board is associated with positive scope economies, possibly due to internal knowledge. However, CEO Chairman duality is associated with equal or larger probability of scope diseconomies, which is consistent with previous findings. Representation of other stakeholders on the MFI board does not affect scope economies. The results seem to support the notion that, in highly uncertain environments, group cohesion may be an advantageous mechanism of…

Governance and scope economies in microfinance institutions

2013

This paper studies the relation between board size and composition and cost savings (scope economies) from combining savings mobilisation and lending by Microfinance Institutions (MFIs). The findings support the hypothesis that employee representation on the board is associated with positive scope economies, possibly due to internal knowledge. However, CEO-Chairman duality is associated with equal or larger probability of scope diseconomies, which is consistent with previous findings. Representation

ESPERIRE MIMETICO E RAZIONALITÀ NEL MODELLO ADORNIANO DI RAPPORTO MENTE-MONDO.

2014

Il saggio ricostruisce il ruolo cognitivo e razionale della mimesi nel modello adorniano di conoscenza come “differenziazione”. Vi è proposta un’interpretazione della capacità del “pensare per costellazioni” e del linguaggio di “cogliere la cosa”, che ne evidenzia la lontananza dal “vecchio realismo della rappresentazione oggettiva (der alte Abbildrealismus)”. Esso mira anche a rendere esplicito come il modello adorniano di conoscenza sia in grado di dar conto di alcune recenti acquisizioni neurofisiologiche su un livello mimetico di rapporto mente-mondo, e come esso contribuisca ad una convincente interpretazione, razionalista ed antiintellettualista ad un tempo, di alcune loro implicazion…

Perception, Normativity and Action in Contemporary Philosophy of Mind and Cognitive Science

Working on the background of a view of mind as “in action”, as pragmatically shaped by its own dynamic interactions with the world, emerging from the achievements of contemporary philosophy of mind (from Searle to enactivism)and cognitive science (from Gibson to Goodale and Milner)I aim to propose a view of perception as a form of human activity of which we are responsible, and in which our “commitment” to truth and rationality can take place. Against some recent phenomenalist and antirepresentationalist views of perception I'll try to show that the action-oriented character of perception does not challenge its rational constraint to a right representation of the state of affairs which it i…

Fango pannonico. Un paradigma populista per Miroslav Krleza

2019

As an obsessive keyword, the Pannonian mud appears in several writings of Miroslav Krleza. It represents the core of Croatian periphery, in particular the Podravina region, which was for long time untouched by modernity, and oppressed by feudal governments even after the fall of the Austrian Empire, from 1918 onwards. In this timeless place watered by the river Drava, the mud acquires a paradigmatic role like a phenomenon that causes historical conflicts. However, its ambiguous status of metahistorical symbol of a long lasting collapse is a contradictory factor, because of the consequences arising from it are unpredictable. As a contribute to this paradoxical attitude some images occur in K…

Formal Modeling and Discrete-Time Analysis of BPEL Web Services

2008

International audience; Web services are increasingly used for building enterprise information systems according to the Service Oriented Architecture (SOA) paradigm. We propose in this paper a tool-equipped methodology allowing the formal modeling and analysis of Web services described in the BPEL language. The discrete-time transition systems modeling the behavior of BPEL descriptions are obtained by an exhaustive simulation based on a formalization of BPEL semantics using the Algebra of Timed Processes (ATP). These models are then analyzed by model checking value-based temporal logic properties using the CADP toolbox. The approach is illustrated with the design of a Web service for GPS na…

Learning Pros and Cons of Model-Driven Development in a Practical Teaching Experience

2016

Current teaching guides on Software Engineering degree focus mainly on teaching programming languages from the first courses. Conceptual modeling is a topic that is only taught in last courses, like master courses. At that point, many students do not see the usefulness of conceptual modeling and most of them have difficulty to reach the level of abstraction needed to work with them. In order to make the learning of conceptual modeling more attractive, we have conducted an experience where students compare a traditional development versus a development using conceptual models through a Model-Driven Development (MDD) method. This way, students can check on their own pros and cons of working w…

Visual servo control using orthinormal polynomial

2003

This paper describes an application of the visual servoing approach to vision-based control in robotics. The basic idea addresses the use of a vision sensor in the feedback loop within the controlled vision framework. It consists in tracking of arbitrary 3-D objects travelling at unknown velocities in a 2-D space (depth is given as known). Once the necessary modeling stage is performed, the framework becomes one of automatic control, and naturally stability, performance and robustness questions arise. Here, we consider to track line segments corresponding to the edges extracted from the image being analyzed. Two representations for a line segment are presented and discussed, and an appropri…

Functional cysteine-less subunits of the transporter associated with antigen processing (TAP1 and TAP2) by de novo gene assembly

2002

AbstractWithin the adaptive immune system the transporter associated with antigen processing (TAP) plays a pivotal role in loading of peptides onto major histocompatibility (MHC) class I molecules. As a central tool to investigate the structure and function of the TAP complex, we created cysteine-less human TAP subunits by de novo gene synthesis, replacing all 19 cysteines in TAP1 and TAP2. After expression in TAP-deficient human fibroblasts, cysteine-less TAP1 and TAP2 are functional with respect to adenosine triphosphate (ATP)-dependent peptide transport and inhibition by ICP47 from herpes simplex virus. Cysteine-less TAP1 and TAP2 restore maturation and intracellular trafficking of MHC c…