Search results for "Principal component"

Mobile phone data statistics as a dynamic proxy indicator in assessing regional economic activity and human commuting patterns

2020

Distinct Patterns of Functional Connectivity During the Comprehension of Natural, Narrative Speech.

2020

Recent continuous task studies, such as narrative speech comprehension, show that fluctuations in brain functional connectivity (FC) are altered and enhanced compared to the resting state. Here, we characterized the fluctuations in FC during comprehension of speech and time-reversed speech conditions. The correlations of Hilbert envelope of source-level EEG data were used to quantify FC between spatially separate brain regions. A symmetric multivariate leakage correction was applied to address the signal leakage issue before calculating FC. The dynamic FC was estimated based on a sliding time window. Then, principal component analysis (PCA) was performed on individually concatenated and te…

Sorting of Single Biomolecules based on Fourier Polar Representation of Surface Enhanced Raman Spectra

2016

AbstractSurface enhanced Raman scattering (SERS) spectroscopy becomes increasingly used in biosensors for its capacity to detect and identify single molecules. In practice, a large number of SERS spectra are acquired and reliable ranking methods are thus essential for analysing all these data. Supervised classification strategies, which are the most effective methods, are usually applied but they require pre-determined models or classes. In this work, we propose to sort SERS spectra in unknown groups with an alternative strategy called Fourier polar representation. This non-fitting method based on simple Fourier sine and cosine transforms produces a fast and graphical representation for sor…

pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components

2019

AbstractBackgroundPrincipal component analysis (PCA) is frequently useentirely written ind in genomics applications for quality assessment and exploratory analysis in high-dimensional data, such as RNA sequencing (RNA-seq) gene expression assays. Despite the availability of many software packages developed for this purpose, an interactive and comprehensive interface for performing these operations is lacking.ResultsWe developed the pcaExplorer software package to enhance commonly performed analysis steps with an interactive and user-friendly application, which provides state saving as well as the automated creation of reproducible reports. pcaExplorer is implemented in R using the Shiny fra…

Missing Data

2009

In this chapter, we deal with the problem of missing data in principal component analysis (PCA) and partial least squares (PLS) methods. First, we review several statistical methods proposed in the literature for handling missing data. Both single and multiple imputation (MI) methods are studied and compared using simulated data. After this, we particularize the missing data problem for building and exploiting multivariate calibration models. Several approaches proposed in the literature are introduced and their performance compared based on several real data sets.

Feature Dimensionality Reduction for Mammographic Report Classification

2016

The amount and the variety of available medical data coming from multiple and heterogeneous sources can inhibit analysis, manual interpretation, and use of simple data management applications. In this paper a deep overview of the principal algorithms for dimensionality reduction is carried out; moreover, the most effective techniques are applied on a dataset composed of 4461 mammographic reports is presented. The most useful medical terms are converted and represented using a TF-IDF matrix, in order to enable data mining and retrieval tasks. A series of query have been performed on the raw matrix and on the same matrix after the dimensionality reduction obtained using the most useful techni…

Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy …

2020

PLOS ONE 15(5), e0230141 (2020). doi:10.1371/journal.pone.0230141

Atrial activity extraction for atrial fibrillation analysis using blind source separation.

2004

This contribution addresses the extraction of atrial activity (AA) from real electrocardiogram (ECG) recordings of atrial fibrillation (AF). We show the appropriateness of independent component analysis (ICA) to tackle this biomedical challenge when regarded as a blind source separation (BSS) problem. ICA is a statistical tool able to reconstruct the unobservable independent sources of bioelectric activity which generate, through instantaneous linear mixing, a measurable set of signals. The three key hypothesis that make ICA applicable in the present scenario are discussed and validated: 1) AA and ventricular activity (VA) are generated by sources of independent bioelectric activity; 2) AA …

Wi-Sense: a passive human activity recognition system using Wi-Fi and convolutional neural network and its integration in health information systems

2021

AbstractA human activity recognition (HAR) system acts as the backbone of many human-centric applications, such as active assisted living and in-home monitoring for elderly and physically impaired people. Although existing Wi-Fi-based human activity recognition methods report good results, their performance is affected by the changes in the ambient environment. In this work, we present Wi-Sense—a human activity recognition system that uses a convolutional neural network (CNN) to recognize human activities based on the environment-independent fingerprints extracted from the Wi-Fi channel state information (CSI). First, Wi-Sense captures the CSI by using a standard Wi-Fi network interface car…

Feature selection with Ant Colony Optimization and its applications for pattern recognition in space imagery

2016

This paper presents a feature selection (FS) algorithm using Ant Colony Optimization (ACO). It is inspired by the particular behavior of real ants, namely by the fact that they are capable of finding the shortest path between a food source and the nest. There are considered two ACO-FS model applications for pattern recognition in remote sensing imagery: ACO Band Selection (ACO-BS) and ACO Training Label Purification (ACO-TLP). The ACO-BS reduces dimensionality of an input multispectral image data by selecting the “best” subset of bands to accomplish the classification task. The ACO-TLP selects the most informative training samples from a given set of labeled vectors in order to optimize the…