6533b860fe1ef96bd12c2fe8
RESEARCH PRODUCT
Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy models
Isabel SeiffertChristina MöllerInes KoskaHeidrun PotschkaAndré BleichSteven R. TalbotRene TolbaValentina Di LibertoRoelof Maarten Van Dijksubject
Computer sciencePhysiologyPsychological interventionSocial Sciencescomputer.software_genreOpen fieldField (computer science)Rats Sprague-Dawley0302 clinical medicineMathematical and Statistical TechniquesMedicine and Health SciencesPsychologyCluster Analysis0303 health sciencesPrincipal Component AnalysisMultidisciplinaryAnimal Welfare (journal)Animal BehaviorQStatisticsRAnimal ModelsResearch AssessmentNeurologyExperimental Organism SystemsAnimal SocialityPhysical SciencesMedicineDisease Models Animals epilepsy animal behaviorFemaleLocomotionResearch ArticleScienceSpatial BehaviorContext (language use)Machine learningResearch and Analysis Methods03 medical and health sciencesRobustness (computer science)Animal welfareKindling NeurologicAnimalsRelevance (information retrieval)BurrowingStatistical MethodsSocial BehaviorSelection (genetic algorithm)030304 developmental biologyBehaviorEpilepsybusiness.industryBiological LocomotionBiology and Life SciencesRatsDisease Models AnimalBiological Variation PopulationMultivariate AnalysisAnimal StudiesArtificial intelligenceK Means ClusteringbusinesscomputerZoology030217 neurology & neurosurgeryMathematicsSoftwaredescription
PLOS ONE 15(5), e0230141 (2020). doi:10.1371/journal.pone.0230141
year | journal | country | edition | language |
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2020-01-01 |