Search results for "Proa"

showing 10 items of 1834 documents

The Smith-Robinson Approach to the Subaxial Cervical Spine: A Stepwise Microsurgical Technique Using Volumetric Models From Anatomic Dissections.

2020

BACKGROUND: The Smith-Robinson1 approach (SRA) is the most widely used route to access the anterior cervical spine. Although several authors have described this approach, there is a lack of the stepwise anatomic description of this operative technique. With the advent of new technologies in neuroanatomy education, such as volumetric models (VMs), the understanding of the spatial relation of the different neurovascular structures can be simplified. OBJECTIVE: To describe the anatomy of the SRA through the creation of VMs of anatomic dissections. METHODS: A total of 4 postmortem heads and a cervical replica were used to perform and record the SRA approach to the C4-C5 level. The most relevant…

Anterior cervical approachAnterior cervical approach Anterior neck Cervical spine Smith-Robinson approach Surgical anatomy Volumetric modelsmedicine.medical_treatmentSurgical planningNOSmith-Robinson approach03 medical and health sciences0302 clinical medicineSurgical anatomyVolumetric modelsCervical spinePlatysma musclemedicineHumans030212 general & internal medicineAnterior neckAnterior neckbusiness.industryDissectionSurgical anatomyAnatomyMicrosurgeryNeurovascular bundleCervical spineDissectionCervical VertebraeNeck DissectionSurgeryNeurology (clinical)business030217 neurology & neurosurgeryNeckDiskectomyOperative neurosurgery (Hagerstown, Md.)
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Chemical partitioning and DNA fingerprinting of some pistachio (Pistacia vera L.) varieties of different geographical origin

2019

The genus Pistacia (Anacardiaceae family) is represented by several species, of which only P. vera L. produces edible seeds (pistachio). Despite the different flavor and taste, a correct identification of pistachio varieties based on the sole phenotypic character is sometimes hard to achieve. Here we used a combination of chemical partitioning and molecular fingerprinting for the unequivocal identification of commercial pistachio seed varieties (Bronte, Kern, Kerman, Larnaka, Mateur and Mawardi) of different geographical origin. The total phenolic content was higher in the variety Bronte followed by Larnaka and Mawardi cultivars. The total anthocyanin content was higher in Bronte and Larnak…

Anthocyanin0106 biological sciencesAnacardiaceaePlant ScienceHorticulture01 natural sciencesBiochemistryAnthocyaninsLinoleic Acidchemistry.chemical_compoundSettore BIO/10 - BiochimicaProanthocyanidinsAnacardiaceaeCultivarFatty acidsMolecular BiologyPhylogenyFlavonoidsPistacia veraSeedGeographyPistaciabiology010405 organic chemistryInternal transcribed spacer (ITS)General MedicineFatty acidbiology.organism_classificationDNA Fingerprinting0104 chemical sciencesHorticultureAnacardiaceae; Anthocyanins; Fatty acids; Flavonoids; Internal transcribed spacer (ITS); Pistacia vera; Proanthocyanidins; Biochemistry; Molecular Biology; Plant Science; HorticultureProanthocyanidinchemistryDNA profilingAnthocyaninPistacia lentiscusPistaciaSeedsFlavonoidProanthocyanidinMolecular FingerprintingOleic Acid010606 plant biology & botanyPhytochemistry
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GRANULOMATOUS MASTITIS DURING CHRONIC ANTIDEPRESSANT THERAPY: IS IT POSSIBLE A CONSERVATIVE THERAPEUTIC APPROACH?

2012

Granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis, sarcoidosis, foreign body reaction, and mycotic and parasitic infections. In contrast, idiopathic granulomatous mastitis (IGM) is characterized by the presence of chronic granulomatous lobulitis in the absence of an obvious etiology. Clinically and radiologically it may mimic breast carcinoma and so awareness of surgeons, pathologists, and radiologists is essential to avoid unnecessary mastectomies. Cases of IGM are reported during antidepressant therapy in patients also showing high levels of prolactinemia. In these cases, we believe that surgical excision must be avoid…

Antidepressant therapyCancer Researchmedicine.medical_specialtyTuberculosisbusiness.industryDiseaseGranulomatous mastitismedicine.diseaseBrief CommunicationDermatologySurgeryHyperprolactinemiaTherapeutic approachSettore MED/18 - Chirurgia GeneraleBreast cancerOncologySelective serotonin reuptake inhibitorsmedicineEtiologySarcoidosisantidepressant therapy idiopathic granulomatous mastitis selective serotin reuptake inhibitorsIdiopathic granulomatous mastitisbusinessPathological
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Almond (Prunus dulcis cv. Casteltermini) Skin Confectionery By-Products: New Opportunity for the Development of a Functional Blackberry (Rubus ulmifo…

2021

This work proposes for the first time a model for reusing almond (Prunus dulcis cv. Casteltermini from Sicily, Southern Italy) skin to formulate a new functional blackberry (Rubus ulmifolius Schott) jam. For this purpose, blackberries were analysed fresh and as jam, traditionally prepared with a minimum fruit amount of 80%. Different percentages of almond skin (20, 15, and 10% w/w) were added to jam. The phytochemical profile of enriched jam was investigated by LC-ESI/LTQOrbitrap/MS analyses. Anthocyanins, hydrolysable tannins, and triterpenoids were identified in a blackberry extract, while proanthocyanidins, flavonoids, and oxylipins were identified in an almond extract. The n-hexane extr…

AntioxidantPhysiologyDPPHmedicine.medical_treatmentClinical BiochemistryRM1-950carbohydrate hydrolysing enzymesPrunus dulcis cv. Casteltermini skin01 natural sciencesBiochemistrySensory analysisArticlechemistry.chemical_compound0404 agricultural biotechnologylipasemedicineGC–MS<i>Prunus dulcis</i> cv. Casteltermini skinFood scienceBy-products; Carbohydrate hydrolysing enzymes; GC–MS; LC-ESI/LTQOrbitrap/ MS; Lipase; Prunus dulcis cv. Casteltermini skin; Rubus ulmifolius<i>Rubus ulmifolius</i>by-productsMolecular BiologyLC-ESI/LTQOrbitrap/MSABTSRubus ulmifoliusbiologyChemistryBy-products Carbohydrate hydrolysing enzymes GC–MS LC-ESI/LTQOrbitrap/ MS Lipase Prunus dulcis cv. Casteltermini skin Rubus ulmifoliusfungi010401 analytical chemistryfood and beveragesSettore CHIM/06 - Chimica Organica04 agricultural and veterinary sciencesCell Biologybiology.organism_classification040401 food sciencehumanities0104 chemical sciencesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreePrunus dulcisProanthocyanidinPhytochemicalLC-ESI/LTQOrbitrap/ MSTherapeutics. PharmacologyRubus ulmifoliusAntioxidants
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Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a…

2021

Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. Maceration provided the extraction of higher dry matter contents, including total phenolics (TPC), anthocyanins, and condensed tannins, which also impacted higher antioxidant activity. NS and SB extracts presented the highest mean values of TPC and antioxidant activity. Individually, NS extract presented high contents of proanthocyanidins, resveratrol, and some phenolic acids. In contrast, SB contained a high concentration of ellagitannins, ellagic acid, and quercetin, exp…

Antioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsToxicologyAntioxidantschemistry.chemical_compoundRibesAnti-Infective AgentsCandida albicansHippophaeFood sciencenatural resources0303 health sciencesbiologyChemistrybioaktiiviset yhdisteetPinus sylvestris04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceEnterovirus B HumanProanthocyanidinvisual_artPlant Barkvisual_art.visual_art_mediumkiertotalousBarkQuercetinEllagic acidfree radicalsMicrobial Sensitivity Testsvapaat radikaalit03 medical and health sciences0404 agricultural biotechnologyindustrial by-productsCell Line TumormedicineMaceration (wine)HumansPress cakebiomassa (teollisuus)Picea030304 developmental biologyantioksidantitantimikrobiset yhdisteetbioactive compoundsBacteriaPlant Extractscircular economyScots pineGreen Chemistry Technologybiology.organism_classificationluonnonaineetextraction technologiesPlant Leavesuuttosivutuotteetmyrkylliset aineetFood Science
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Poor Esophageal Motility: A Tailored Approach?

2014

New onset dysphagia following antireflux surgery is among the most undesirable side effects of an otherwise excellent therapy. While its cause is multifactorial, insufficient circular muscle strength of the esophageal body, not powerful enough to force the bolus through the distal neo-high pressure zone, can be a component of the pathophysiology. The relative merits of “tailoring” the degree of fundoplication based upon esophageal body motility and/or other clinical features have been debated for decades. Herein we discuss the rationale for a tailored approach, its pros and cons and review data published to date available to guide the clinician in individual patient decision-making.

Antireflux surgerymedicine.medical_specialtyTailored approachbusiness.industryEsophageal bodyDysphagiaNew onsetPoor esophageal motilityCircular musclemedicinemedicine.symptomIntensive care medicinebusinessPartial fundoplication
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Transcervical approach for carotid artery stenting with transitory reversal flow: Case report

2021

Introduction Carotid artery stenting (CAS) has been indicated as an alternative to carotid endarterectomy in high risk patients. Sometimes, an aortic arch can be anatomically unfavourable for CAS. Herein we report our experience in a case of CAS with transcervical approach. Presentation of case A 77-year-old male was referred to our hospital for severe subtotal occlusion of the left internal carotid artery. He had a past medical history of radiation to the head and neck for laryngeal cancer. Previous CT-angiography had shown a type III aortic with bovine arch. CAS via transcervical approach was performed with transitory reversal flow during the placement of RX Spider Filter 6 Fr (Medtronic,…

Aortic archmedicine.medical_specialtymedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentBalloon catheterTranscervical approachCarotid endarterectomySettore MED/22 - Chirurgia VascolareSurgerymedicine.arteryOcclusionAngiographyCase reportmedicinecardiovascular systemSurgeryCommon carotid arteryReversal flowbusinessInternal jugular veinShunt (electrical)Carotid artery stenting
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Regurgitant flow in apparently normal valve prostheses: improved detection and semiquantitative analysis by transesophageal two-dimensional color-cod…

1990

In 128 patients with apparently normally functioning prosthetic valves ( n = 136) in the aortic position ( n = 79) and the mitral position ( n = 57), the prevalence of transprosthetic regurgitant flow was studied by use of transthoracic and transesophageal two-dimensional color-coded Doppler echocardiography. With the transthoracic approach, regurgitant flow was detected in early systole or diastole for 28% of the mitral prostheses and for 29% of the aortic prostheses. With transesophageal color-coded Doppler echocardiography, regurgitant jets were visualized for 95% of the mitral prostheses and for 44% of the aortic prostheses. In 40% of the Bjork-Shiley prostheses and 88% of the St. Jude …

Aortic valveAdultMalemedicine.medical_specialtyAdolescentAortic Valve InsufficiencyDiastoleDoppler echocardiographyInternal medicineMitral valvemedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesSystoleTransthoracic approachAgedmedicine.diagnostic_testbusiness.industryMiddle Agedequipment and suppliesEchocardiography DopplerRegurgitant flowProsthesis Failuremedicine.anatomical_structureAortic ValveHeart Valve Prosthesiscardiovascular systemCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicinebusinessSemi quantitativecirculatory and respiratory physiologyJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
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Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells.

2011

SUMMARYAlthough many cancer cells are primed for apoptosis, they usually develop resistance to cell death at multiple levels. Permeabilization of the outer mitochondrial membrane, which is mediated by proapoptotic Bcl-2 family members like Bax, is considered as a point-of-no-return for initiating apoptotic cell death. This crucial role has placed Bcl-2 family proteins as recurrent targets for anticancer drug development. Here, we propose and demonstrate a new concept based on using minimal active version of Bax to induce cell death independently of endogenous Bcl-2 proteins. We show that membrane-active segments of Bax can directly induce the release of mitochondria-residing apoptogenic fac…

ApoptosisMitochondrionMiceMESH: Protein Structure Tertiary0302 clinical medicineNeoplasmsgeneticsMESH: AnimalsMESH: Neoplasmsbcl-2-Associated X Protein0303 health sciencesbiologyMESH: PeptidesCytochrome capoptosisCytochromes cMESH: Cytochromes cproapoptotic BaxCell biologyMitochondriadrug therapymitochondria030220 oncology & carcinogenesisBacterial outer membraneProgrammed cell deathMESH: Cell Line TumorMESH: MitochondriaAntineoplastic Agents[SDV.CAN]Life Sciences [q-bio]/Cancerpore-forming peptideschemistryArticle03 medical and health sciencesBcl-2-associated X proteinBcl-2 familyCell Line TumorAnimalsHumansMESH: bcl-2-Associated X ProteinMESH: Mice030304 developmental biologyMESH: HumansMESH: ApoptosisBcl-2 familyCell BiologyProtein Structure Tertiaryanticancer agentantivascular therapyApoptosisdrug effectsCancer cellbiology.proteinMESH: Antineoplastic AgentspharmacologyphysiopathologyPeptidesmetabolism
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Impulsive Tests on Historical Structures: The Dome of Teatro Massimo in Palermo

2016

Cultural heritage is the set of things, that having particular historical cultural and aesthetic are of public interest and constitute the wealth and civilization of a place and its people. Sharpen up methodologies aimed at safeguarding of monuments is crucial because the future may have in mind the historical past. Italy is a country that has invested heavily on its historical memory returned in large part by the historical building or the monuments. Furthermore, culture represents a fundamental indicator of the growth of the culture of a country. Consider a monitoring project of one of the most Impressive theater in the world, like “Teatro Massimo” in Palermo (Italy), means to add value t…

ApproachModal analysisExperimental dynamicNoninvasive and nondestructive0211 other engineering and technologies020101 civil engineering02 engineering and technologyBuilding and ConstructionModal analysiFinite element method0201 civil engineeringDome (geology)Teatro massimo dome021105 building & constructionFinite element modelingSystem identificationSettore ICAR/08 - Scienza Delle CostruzioniGeologySeismologyThe Open Construction and Building Technology Journal
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