Search results for "Procedures"

showing 10 items of 1678 documents

“Near-TME”: proposed standardisation of the technique for proctectomy in male patients with ulcerative colitis

2022

Abstract Background The aim of the present study was to describe in detail an approach to proctectomy in ulcerative colitis (UC), which can be standardized; near-total mesorectal excision (near-TME), to prevent injuries to autonomic pelvic nerves and subsequent sexual dysfunction. Methods We demonstrate the technique ex vivo on a cadaver from a male patient in lithotomy position and on a sagittal section of a male pelvis. We also demonstrate the technique in vivo in two male patients diagnosed with UC, with no history of sexual dysfunction or bowel neoplasia. The study was performed at the Human Embryology and Anatomy Department. University of Valencia, Spain. Results The posterolateral dis…

MaleClose rectal dissection:Surgical Procedures Operative::Digestive System Surgical Procedures::Proctectomy [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Pelvi:Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Colitis::Colitis Ulcerative [DISEASES]Inflammatory bowel diseasesInflammatory bowel diseasePelvis:enfermedades del sistema digestivo::enfermedades gastrointestinales::gastroenteritis::colitis::colitis ulcerosa [ENFERMEDADES]Colitis ulcerosa - CirurgiaHumansAutonomic PathwaysUlcerative coliti:intervenciones quirúrgicas::procedimientos quirúrgicos del sistema digestivo::proctectomía [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]ProctectomyRectal NeoplasmsRectumGastroenterology:Otros calificadores::Otros calificadores::/cirugía [Otros calificadores]Surgical anatomyExtirpació (Cirurgia)Intra-mesorectal:Other subheadings::Other subheadings::/surgery [Other subheadings]Ulcerative colitisAutonomic PathwayColitis UlcerativeSurgerysense organsHumanTechniques in Coloproctology
researchProduct

Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras

2021

Aim The aim of this study was to analyze changes in the incidence, management and mortality of DFU in Sicilian Type 2 diabetic patients hospitalized between two eras, i.e. 2008–2013 and 2014–2019. Methods We compared the two eras, era1: 2008–13, era2: 2014–19. In era 1, n = 149, and in era 2, n = 181 patients were retrospectively enrolled. Results In the population hospitalized for DFU in 2008–2013, 59.1% of males and 40.9% of females died, whilst in 2014–2019 65.9% of males and 34.1% of females died. Moderate chronic kidney disease (CKD) was significantly higher in patients that had died than in ones that were alive (33% vs. 43%, p < 0.001), just as CKD was severe (14.5% vs. 4%, p <…

MaleComorbidityAntiplatelet TherapyBiochemistrySettore MED/13 - EndocrinologiaEndocrinologyMedical ConditionsOral DiseasesRetrospective StudieChronic Kidney DiseaseMedicine and Health SciencesSurgical AmputationInsulinSicilyUlcersAged 80 and overMultidisciplinaryPharmaceuticsIncidenceQRMiddle AgedDiabetic FootType 2 DiabetesHospitalizationNephrologyMedicineFemaleHumanResearch ArticleEndocrine DisordersScienceOral MedicineSurgical and Invasive Medical ProceduresSigns and SymptomsLife ExpectancyDrug TherapyDiabetes MellitusRenal DiseasesHumansMortalityRenal Insufficiency ChronicAgedRetrospective StudiesDiabetic EndocrinologyBiology and Life SciencesHormonesDiabetes Mellitus Type 2Metabolic DisordersClinical MedicinePLoS ONE
researchProduct

Absolok® versus Hem-o-Lok® clips for renorrhaphy during partial nephrectomy for parenchymal renal tumors

2020

Background To compare perioperative and functional outcomes associated with renorrhaphy performed with two different types of clips (Absolok® vs. Hem-o-Lok®) in a contemporary series of patients who underwent partial nephrectomy. Methods Patients in whom Absolok® clips were used to perform haemostasis at the level of tumor bed or to block the running sutures during sliding-clip renorrhaphy (study group) were compared with a contemporary control group of patients in whom renorrhaphy was performed with Hem-o-Lok® clips. Both groups received the same surgical technique via an open or robot-assisted approach. Inner renorrhaphy was performed with one or more 3-0 (26 mm needle) monofilament runni…

MaleComplicationsmedicine.medical_treatment030232 urology & nephrologyKidneyNephrectomyPolydioxanonechemistry.chemical_compoundPostoperative Complications0302 clinical medicinePerioperative outcomesRobotic Surgical ProceduresSuture (anatomy)bsolok® clipPartial nephrectomyMedicineProspective StudiesCLIPSIntraoperative ComplicationsProspective cohort studycomputer.programming_languageMiddle AgedSurgical InstrumentsMagnetic Resonance ImagingRenal cell carcinomaKidney NeoplasmsNephrectomyTreatment Outcomesurgical procedures operativeNephrologyPolydioxanone030220 oncology & carcinogenesiscardiovascular systemFemalePositive Surgical MarginAbsolok (R) clips Hem-o-lok (R) clips Renorrhaphy Sliding clip technique Partial nephrectomy Perioperative outcomes Complications Renal cell carcinomaPerioperative outcomeHem-o-Lok® clipmedicine.medical_specialtyKidney CortexUrologyeducationSliding clip technique03 medical and health sciencesHumansRenorrhaphycardiovascular diseasesAgedHemostasisAbsolok (R) clipsSuturesbusiness.industryPerioperativeSurgeryHem-o-lok (R) clipschemistryHemostasisTomography X-Ray ComputedbusinessComplicationcomputerMinerva Urologica e Nefrologica
researchProduct

Efficacy and safety of decompressive craniectomy with non-suture duraplasty in patients with traumatic brain injury.

2020

AbstractBackgroundDecompressive craniectomy is an important surgical treatment for patients with severe traumatic brain injury (TBI). Several reports have been published on the efficacy of non-watertight sutures in duraplasty performed in decompressive craniectomy. This study aims to evaluate the effectiveness of dura closure without sutures (non-suture duraplasty) in decompressive craniectomy for TBI.MethodsOne hundred and six patients were enrolled at a single trauma center between January 2017 and December 2018. We retrospectively collected the data and classified the patients into non-suture and suture duraplasty craniectomy groups. We compared the characteristics of patients and their …

MaleCritical Care and Emergency MedicineTraumatic Brain InjuryPhysiologymedicine.medical_treatmentBlood Loss SurgicalGlasgow Outcome ScaleNervous SystemVascular MedicineDiagnostic RadiologyNervous System Procedures0302 clinical medicineSuture (anatomy)AntibioticsBrain Injuries TraumaticMedicine and Health SciencesSurgical treatmentTomographyTrauma MedicineCerebrospinal FluidMultidisciplinaryAntimicrobialsRadiology and ImagingGlasgow Outcome ScaleTrauma centerQRDrugsMiddle AgedSevere Blood LossCranioplastySutureless Surgical ProceduresBody FluidsTreatment OutcomeMedicineFemaleDecompressive craniectomyAnatomyTraumatic InjuryResearch ArticleAdultDecompressive Craniectomymedicine.medical_specialtyImaging TechniquesTraumatic brain injuryScienceOperative TimeTrauma SurgerySurgical and Invasive Medical ProceduresNeuroimagingHemorrhageResearch and Analysis MethodsMicrobiologyCranioplasty03 medical and health sciencesSigns and SymptomsBlood lossDiagnostic MedicineMicrobial ControlmedicineHumansIn patientRetrospective StudiesPharmacologybusiness.industryBiology and Life Sciences030208 emergency & critical care medicinemedicine.diseaseComputed Axial TomographySurgeryDura MaterClinical MedicinebusinessNeurotraumaTrauma surgery030217 neurology & neurosurgeryNeurosciencePLoS ONE
researchProduct

Comparison of Epithor clinical national database and medico-administrative database to identify the influence of case-mix on the estimation of hospit…

2019

BackgroundThe national Epithor database was initiated in 2003 in France. Fifteen years on, a quality assessment of the recorded data seemed necessary. This study examines the completeness of the data recorded in Epithor through a comparison with the French PMSI database, which is the national medico-administrative reference database. The aim of this study was to demonstrate the influence of data quality with respect to identifying 30-day mortality hospital outliers.MethodsWe used each hospital's individual FINESS code to compare the number of pulmonary resections and deaths recorded in Epithor to the figures found in the PMSI. Centers were classified into either the good-quality data (GQD) …

MaleDatabases FactualOutliers DRGPulmonologyCancer Treatment030204 cardiovascular system & hematologyLogistic regressionHealth administration0302 clinical medicineHospital AdministrationInterquartile rangeMedicine and Health SciencesMedicineHospital MortalityRespiratory System ProceduresMultidisciplinaryMortality rateQRRegression analysisHospitals3. Good healthSurgical OncologyOncologyMedicineFemaleRisk AdjustmentLung ResectionResearch ArticleClinical OncologyDeath RatesScienceSurgical and Invasive Medical Procedures03 medical and health sciencesCase mix indexPopulation MetricsHumansDiagnosis-Related GroupsPopulation BiologySurgical Resectionbusiness.industryBiology and Life SciencesModels TheoreticalHealth CareStandardized mortality ratioLogistic ModelsDyspnea030228 respiratory systemHealth Care Facilities[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieData quality[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieClinical MedicinebusinessDemography
researchProduct

Late-onset Crohn's disease: a comparison of disease behaviour and therapy with younger adult patients: the Italian Group for the Study of Inflammator…

2019

BACKGROUND Disease phenotype and outcome of late-onset Crohn's disease are still poorly defined. METHODS In this Italian nationwide multicentre retrospective study, patients diagnosed ≥65 years (late-onset) were compared with young adult-onset with 16-39 years and adult-onset Crohn's disease 40-64 years. Data were collected for 3 years following diagnosis. RESULTS A total of 631 patients (late-onset 153, adult-onset 161, young adult-onset 317) were included. Colonic disease was more frequent in late-onset (P < 0005), stenosing behaviour was more frequent than in adult-onset (P < 0003), but fistulising disease was uncommon. Surgery rates were not different between the three age groups. Syste…

MaleDiseaseConstriction PathologictumoursInflammatory bowel diseaseLate Onset DisordersCohort Studiessurgery0302 clinical medicineCrohn DiseaseLate Onset DisordersMedicineYoung adultDigestive System Surgical ProceduresCrohn's diseaseGastroenterologyIleitisMiddle AgedColitisItaly030220 oncology & carcinogenesisoutcome030211 gastroenterology & hepatologyFemaleColorectal NeoplasmsCohort studysteroidsAdultmedicine.medical_specialtyAdolescentcomorbiditieselderly03 medical and health sciencesYoung AdultInternal medicineIntestinal FistulaHumansImmunologic FactorsGlucocorticoidsAgedRetrospective StudiesPolypharmacyHepatologybusiness.industrythiopurinesRetrospective cohort studymedicine.diseasecomorbidities; elderly; outcome; steroids; surgery; thiopurines; tumoursPolypharmacyTumor Necrosis Factor Inhibitorsbusiness
researchProduct

The Impact of Endoscopic Ultrasound and Computed Tomography on the TNM Staging of Early Cancer in Barrett's Esophagus

2006

Computed tomography (CT) and endoscopic ultrasound (EUS) are part of the regular staging protocol in esophageal cancer. The value of the two methods was assessed in patients with early cancer in Barrett's esophagus.One hundred consecutive patients (median age 64 yr, interquartile range [IQR] 58-72) with suspected early cancer in Barrett's esophagus who were referred to our hospital for endoscopic therapy were prospectively included in a standardized staging program with upper gastrointestinal endoscopy, EUS (7.5 MHz in all cases plus 12.5 or 20 MHz for elevated and/or depressed lesions), CT of the chest and upper abdomen, and abdominal ultrasonography. The results were summarized in accorda…

MaleEndoscopic ultrasoundmedicine.medical_specialtyEarly cancerEsophageal NeoplasmsAdenocarcinomadigestive systemEndosonographyBarrett EsophagusPredictive Value of TestsmedicineHumansProspective StudiesEsophagusneoplasmsAgedNeoplasm StagingHepatologymedicine.diagnostic_testbusiness.industryEsophageal diseaseUltrasoundGastroenterologyReproducibility of ResultsMiddle Agedmedicine.diseasedigestive system diseasesEndoscopystomatognathic diseasessurgical procedures operativemedicine.anatomical_structureBarrett's esophagusFemaleRadiologyTomographyTomography X-Ray ComputedbusinessThe American Journal of Gastroenterology
researchProduct

Virtual temporal bone: an interactive 3-dimensional learning aid for cranial base surgery.

2009

OBJECTIVE: We have developed an interactive virtual model of the temporal bone for the training and teaching of cranial base surgery. METHODS: The virtual model was based on the tomographic data of the Visible Human Project. The male Visible Human's computed tomographic data were volumetrically reconstructed as virtual bone tissue, and the individual photographic slices provided the basis for segmentation of the middle and inner ear structures, cranial nerves, vessels, and brainstem. These structures were created by using outlining and tube editing tools, allowing structural modeling either directly on the basis of the photographic data or according to information from textbooks and cadaver…

MaleEngineering drawingmedicine.medical_specialtyNeuronavigationSoftware ValidationWorkspaceVirtual realityprojectsNeurosurgical ProceduresUser-Computer InterfaceCadaverTemporal bonemedicineImage Processing Computer-AssistedHumansSegmentationIntraoperative ComplicationsNeuronavigationSkull BaseCranial Fossa Middlebusiness.industryVisible human projectDissectionTeachingTemporal BoneVisible Human ProjectsVestibulocochlear NerveSurgeryDextroscopeFacial Nerveprojects.projectEducation Medical GraduateEar InnerSurgeryNeurology (clinical)businessCarotid Artery InternalSoftwarePetrous BoneNeurosurgery
researchProduct

The economic burden of endoscopic treatment for anastomotic leaks following oncological Ivor Lewis esophagectomy

2019

BackgroundComplications after surgery for esophageal cancer are associated with significant resource utilization. The aim of this study was to analyze the economic burden of two frequently used endoscopic treatments for anastomotic leak management after esophageal surgery: Treatment with a Self-expanding Metal Stent (SEMS) and Endoscopic Vacuum Therapy (EVT).Materials and methodsBetween January 2012 and December 2016, we identified 60 German-Diagnosis Related Group (G-DRG) cases of patients who received a SEMS and / or EVT for esophageal anastomotic leaks. Direct costs per case were analyzed according to the Institute for Remuneration System in Hospitals (InEK) cost-accounting approach by c…

MaleEsophageal NeoplasmsEconomicsmedicine.medical_treatmentCancer TreatmentSocial SciencesAnastomotic LeakIndirect costs0302 clinical medicineCost of IllnessMedicine and Health SciencesAged 80 and overMultidisciplinarymedicine.diagnostic_testQREsophageal cancerMiddle AgedSurgical OncologyOncologyEsophagectomy030220 oncology & carcinogenesisMedicine030211 gastroenterology & hepatologyFemaleResearch ArticleClinical OncologyAdultmedicine.medical_specialtyVacuumScienceSelf Expandable Metallic StentsSurgical and Invasive Medical ProceduresAnastomosis03 medical and health sciencesDigestive System ProceduresHealth EconomicsEsophagusAnastomotic leaksmedicineIvor lewisHumansddc:610Agedbusiness.industryStentEndoscopymedicine.diseaseEndoscopySurgeryHealth CareEsophagectomyClinical MedicinebusinessPLoS ONE
researchProduct

Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

2015

Background/objectivesObesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two endothelin receptors mediate arsenic-stimulated adipocyte dysfunction, and endothelin system can regulate adiposity by modulating adiponectin activity in different situations and, therefore, influence obesity development. The aim of the present study was to analyze if single nucleotide polymorphisms (SNPs) in the EDN system could be associated with human obesity.Subjects/methodsWe analyz…

MaleEspañaObesidad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Fat Distribution::Adiposity [Medical Subject Headings]Endothelins:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Endothelins [Medical Subject Headings]Polymorphism (computer science)Risk Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity [Medical Subject Headings]:Chemicals and Drugs::Inorganic Chemicals::Elements::Arsenic [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]education.field_of_studyMultidisciplinary:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]Genètica humanaEndothelinsQRMiddle AgedPrognosisReceptor Endothelin APolimorfismo de nucleótido único:Anatomy::Cells::Connective Tissue Cells::Adipocytes [Medical Subject Headings]ObesitatMedicineFemaleTomografía computarizada por rayos X:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]Endothelin receptor:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation Computer-Assisted::Tomography X-Ray Computed [Medical Subject Headings]Research Articlemedicine.hormonemedicine.medical_specialtyGenotype:Phenomena and Processes::Mathematical Concepts::Probability::Risk [Medical Subject Headings]SciencePopulationSingle-nucleotide polymorphism:Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipolysis [Medical Subject Headings]BiologyPolymorphism Single NucleotideArsenicReceptores de endotelinasInternal medicineAdipocitos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors Peptide::Receptors Endothelin [Medical Subject Headings]medicineHumansGenetic Predisposition to DiseaseObesityeducation:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]AdiponectinHaplotypeEnfermedad crónicamedicine.diseaseObesityEndocrinologyHaplotypesSpain:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Adipokines::Adiponectin [Medical Subject Headings]GenotipoFollow-Up StudiesArsénicoPLoS ONE
researchProduct