Search results for "Process"

showing 10 items of 22310 documents

Synthesis and studies of calcium channel blocking and antioxidant activities of novel 4-pyridinium and/or N-propargyl substituted 1,4-dihydropyridine…

2014

The novel 1,4-dihydropyridine derivatives containing the cationic pyridine moiety at the position 4, and the N-propargyl group as a substituent at position 1 of the 1,4-DHP cycle were designed, synthesised, and assessed in biological tests. Among all the novel compounds, the 4-(N-dodecyl) pyridinium group-containing compounds 11 (without the N-propargyl group) and 12 (with the N-propargyl group) demonstrated the highest calcium antagonistic properties against neuroblastoma SH-SY5Y (IC50 about 5–14 mM) and the vascular smooth muscle A7r5 cell (IC50 – 0.6–0.7 mM) lines, indicating that they predominantly target the L-type calcium channels. These compounds showed a slight total antioxidant act…

AntioxidantVoltage-dependent calcium channelChemistryStereochemistryGeneral Chemical EngineeringCalcium channelmedicine.medical_treatmentSubstituentCationic polymerizationchemistry.chemical_elementGeneral ChemistryCalciumN-Dodecyl pyridiniumMitochondrial processesStructure–activity relationshipschemistry.chemical_compound14-DihydropyridinesAntioxidant activityPropargylmedicineCalcium antagonistsPyridiniumPropargyl substituentComptes Rendus Chimie
researchProduct

Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosme…

2020

The aim of this paper was to obtain different extracts from the aerial parts of Mesembryanthemum nodiflorum, comparing traditional extraction (using solvents with increasing polarity such as hexane, ethanol 80%, acetone 70% and water) with an eco-friendly technique (supercritical fluid extraction (SFE))

AntioxidantantioxidantDPPHmedicine.medical_treatmentice plant01 natural sciencesSFEIntegrin 1lcsh:Technologylcsh:Chemistry03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - Zoocolturemedicineoxidative stressGeneral Materials ScienceMesembryanthemum nodiflorumFood scienceInstrumentationlcsh:QH301-705.5030304 developmental biologyFluid Flow and Transfer Processes0303 health sciencescell cultureSirt1biologyChemistrylcsh:TProcess Chemistry and TechnologyExtraction (chemistry)General EngineeringSupercritical fluid extractionIntegrin α1biology.organism_classificationlcsh:QC1-9990104 chemical sciencesComputer Science Applications010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999Polyphenollcsh:TA1-2040Oxidative strelcsh:Engineering (General). Civil engineering (General)Cosmeceuticallcsh:PhysicsApplied Sciences
researchProduct

Bioactive peptides as natural antioxidants in food products - A review

2018

Background: Diseases related to oxidative stress and food quality decay are of major concern worldwide as they can lead to economic losses in both public health and food production. The antioxidant peptides, extracted from food proteins, can be explored as natural new drug and food ingredient. Scope and approach Antioxidant peptides are extracted from non-antioxidant precursor proteins from different origin by the activity of either proteolytic microorganisms or isolated enzymes. In the present review, the main sources of bioactive peptides will be discussed. Moreover, the current strategies to obtain these compounds as well as their health benefits and in vivo biological effects will be ev…

Antioxidantfood.ingredientProteolysismedicine.medical_treatmentFood technologyIngredient0404 agricultural biotechnologyfoodmedicinechemistry.chemical_classificationmedicine.diagnostic_testChemistrybusiness.industryFood additiveActive amino acid sequence04 agricultural and veterinary sciencesFood additives040401 food scienceEnzymeBiochemistryOxidative stressProteolysisFood processingbusinessFood qualityFood ScienceBiotechnologyAntioxidant defencesFood quality
researchProduct

Proteomic Analysis of Saccharomyces cerevisiae Response to Oxidative Stress Mediated by Cocoa Polyphenols Extract

2020

The present study addressed the protective effects against oxidative stress (OS) of a cocoa powder extract (CPEX) on the protein expression profile of S. cerevisiae. A proteomic analysis was performed after culture preincubation with CPEX either without stress (&minus

Antioxidantmedicine.medical_treatmentSaccharomyces cerevisiaePharmaceutical Scienceantioxidant activitySaccharomyces cerevisiaeamino acid metabolismmedicine.disease_causeAmino acid metabolismAnalytical Chemistrycocoa polyphenolslcsh:QD241-441<i>Saccharomyces cerevisiae</i>03 medical and health sciencesHistone H3chemistry.chemical_compoundBiosynthesisAntioxidant activitylcsh:Organic chemistryprotein identificationDrug DiscoverymedicineDeletion mutantsoxidative stressPhysical and Theoretical ChemistryReactive oxygen species metabolic process030304 developmental biologychemistry.chemical_classification0303 health sciencesbiologyCocoa polyphenolsChemistry030302 biochemistry & molecular biologyOrganic Chemistrybiology.organism_classificationYeastAmino acidBiochemistryChemistry (miscellaneous)Oxidative stressMolecular MedicineProtein identificationdeletion mutantsOxidative stressMolecules
researchProduct

Solvent-free microwave-assisted extraction of polyphenols from olive tree leaves: Antioxidant and antimicrobial properties

2017

International audience; Response surface methodology (RSM) and artificial neural networks (ANN) were evaluated and compared in order to decide which method was the most appropriate to predict and optimize total phenolic content (TPC) and oleuropein yields in olive tree leaf (Olea europaea) extracts, obtained after solvent-free microwave- assisted extraction (SFMAE). The SFMAE processing conditions were: microwave irradiation power 250-350 W, extraction time 2-3 min, and the amount of sample 5-10 g. Furthermore, the antioxidant and antimicrobial activities of the olive leaf extracts, obtained under optimal extraction conditions, were assessed by several in vitro assays. ANN had better predic…

Antioxidantmedicine.medical_treatment[SDV]Life Sciences [q-bio]Pharmaceutical ScienceAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug Discovery[SDV.IDA]Life Sciences [q-bio]/Food engineeringAntimicrobial; Antioxidant; Oleuropein; Olive leaves; Optimization; Solvent-free microwave extraction; Organic ChemistryOlive leavesMicrowaves04 agricultural and veterinary sciences040401 food scienceAnti-Bacterial AgentsChemistry (miscellaneous)Molecular MedicineAntioxidantAntibacterial activityOptimizationStaphylococcus aureusMicrobial Sensitivity TestsArticlelcsh:QD241-4410404 agricultural biotechnologyOlive leaflcsh:Organic chemistryOleuropeinOleaStaphylococcus epidermidismedicine[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringResponse surface methodologyPhysical and Theoretical ChemistryOleuropeinolive leaves; solvent-free microwave extraction; oleuropein; antioxidant; antimicrobial; optimizationChromatographyPlant ExtractsExtraction (chemistry)Organic ChemistryPolyphenolsolive leaves;solvent-free microwave extraction;oleuropein;antioxidant;antimicrobial;optimizationPlant LeaveschemistryPolyphenolYield (chemistry)Solvent-free microwave extractionSolventsAntimicrobialNeural Networks Computer
researchProduct

Screening of antioxidant potentials and bioactive properties of the extracts obtained from two Centaurea L. species (C. kroumirensis coss. and C. sic…

2020

Herbal medicines, dietary supplements, or infusions with health promoting effects can note strong consumer demand. Hence, researchers and scientists have been increasingly focusing on the promotion of medicinal plants. In this respect, the present study has the evaluation of the biological properties of different extracts (hexane, chloroform, methanol, ultrasonic, essential oil, and supercritical) obtained from two Centaurea species (C. kroumirensis (Coss.) and C. sicula L. subsp sicula) as purpose. Antioxidative activities were assessed by in vitro assays including total phenolic content, free radical scavenging assay and ferric ion reducing power. Among the fourteen extracts examined, the…

Antioxidantphenolicsmedicine.medical_treatmentSonicationmedicine.disease_causelcsh:Technology01 natural scienceslaw.inventionProtective effectlcsh:Chemistrychemistry.chemical_compound0404 agricultural biotechnologyNutraceutical<i>Centaurea</i> spp.lawmedicineGeneral Materials ScienceFood scienceHydrogen peroxideMedicinal plantslcsh:QH301-705.5InstrumentationEssential oilFluid Flow and Transfer Processesbiologylcsh:TProcess Chemistry and TechnologyGeneral Engineering04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencelcsh:QC1-9990104 chemical sciencesComputer Science ApplicationsPlant extract010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999chemistryPhenoliclcsh:TA1-2040CentaureaCentaurea sppAntioxidantlcsh:Engineering (General). Civil engineering (General)lcsh:PhysicsOxidative stress
researchProduct

Entorn de l'origen de la teoria sociocultural: la zona de desenrotllament pròxim en la vida de Vigotsky

2015

Aquest treball presenta la Zona de Desenvolupament Pròxim (ZDP) en la vida de Lev Vigostky, com el punt d'inflexió en l'origen de l'explicació sociocultural sobre l'origen dels processos psicològics superiors. La ZDP té la capacitat d'entendre aquest salt qualitatiu, en la vida d'aquest autor, ja que rescata el context social i cultural com a part la pròpia explicació del desenvolupament personal que, en el cas de Vigostky, discorre des de l'estètica a la Psicologia emprant la dialèctica com a mètode. Per tant, el paper instrumental de la dialèctica, una formació profundament humanística i la necessitat una resposta nova al problema de la consciència en un moment conceptual i polític crític…

Anàlisi microgenètic aprenentatge teoria sociocultural processos psicològics superiors zona de desenvolupament pròxim. Artículo:PSICOLOGÍA [UNESCO]General Earth and Planetary SciencesUNESCO::PSICOLOGÍAGeneral Environmental Science
researchProduct

Cambios de usos del suelo y régimen hídrico en la rambla de Poyo y el barranc de Carraixet

2002

421 pages; http://www.tesisenxarxa.net/TDX-0218104-092141/index_cs.html#documents

Análisis espacio-temporalRambla de PoyononeSistemas de Información GeográficaBarranc de CarraixetComputingMethodologies_DOCUMENTANDTEXTPROCESSING502GeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)Cubiertas del sueloGeografia
researchProduct

Sporta arbitrāžas tiesas jurisdikcija

2017

Sporta arbitrāžas tiesas piedāvātie strīdu šķiršanas mehānismi, kā arī tās neatkarība un specializācija lēmumu pieņemšanā strīdos, kas saistīti ar sportu, ir ļoti nozīmīgi, jo sporta sacensībām pēc būtības ir īslaicīgs raksturs, kā rezultātā, izmantojot Sporta arbitrāžas tiesas piedāvātās iespējas, pastāv lielāka varbūtība uzturēt labklājību un izaugsmes iespējas sportā. Tādēļ pētnieciskā darba “Sporta arbitrāžas tiesas jurisdikcija” mērķis ir izpētīt Sporta arbitrāžas tiesas jurisdikciju un secināt trūkumus, kas saistīti ar Sporta arbitrāžas tiesas jurisdikcijas noteikšanu. Lai gūtu ieskatu Sporta arbitrāžas tiesas praksē darba tēmas ietvaros, galvenokārt tika izmantota ārzemju literatūra …

Apelācijas šķīrējtiesas processSporta arbitrāžas tiesas jurisdikcijaVienkāršais šķīrējtiesas processVienošanās par vēršanos Sporta arbitrāžas tiesāJuridiskā zinātneŠķīrējtiesas klauzula
researchProduct

Lensless object scanning holography for two-dimensional mirror-like and diffuse reflective objects

2013

Recently proposed lensless object scanning holography (LOSH) [Opt. Express 20, 9382 (2012)] is a fully lensless method capable of improving the image quality in digital Fourier holography applied to one-dimensional (1D) reflective objects and it involves a very simplified experimental setup. LOSH is based on the recording and digital postprocessing of a set of digital lensless Fourier transform holograms, which finally results in a synthetic image with improved resolution, field-of-view (FOV), signal-to-noise ratio (SNR), and depth of field. In this paper, LOSH is extended to the cases of two-dimensional (2D) mirror-like and 1D diffuse-based objects. For 2D mirror-like objects, the experime…

ApertureImage qualityComputer sciencebusiness.industryHolographyImage processingSuperresolutionAtomic and Molecular Physics and Opticslaw.inventionSpeckle patternOpticslawDigital image processingDepth of fieldElectrical and Electronic EngineeringbusinessEngineering (miscellaneous)Image resolutionDigital holographyFresnel diffractionApplied Optics
researchProduct