Search results for "Prognose"
showing 3 items of 3 documents
Découvrir l'imposteur : expertises dans la prison de Valence au milieu du xve siècle
2020
Les médecins étaient souvent appelés à intervenir en tant qu’experts dans les cours de justice de la ville de Valence à la fin du Moyen Âge. Ils étaient sollicités pour des raisons diverses et on attendait d’eux qu’ils rendent des jugements ou des pronostics. Un des cadres dans lesquels ils apparaissaient est la prison. La torture faisait partie du développement des procédures judiciaires en tant qu’élément destiné à prouver les faits, pour empêcher que le juge ait le moindre doute. Les doutes suscités par de possibles simulations requéraient les compétences de ces experts, à qui revenait la décision d’infliger ou non la torture au prisonnier. Cet article analyse par le menu un cas particul…
Characteristics and Clinical Outcome of Breast Cancer Patients with Asymptomatic Brain Metastases
2020
Background: Brain metastases (BM) have become a major challenge in patients with metastatic breast cancer. Methods: The aim of this analysis was to characterize patients with asymptomatic BM (n = 580) in the overall cohort of 2589 patients with BM from our Brain Metastases in Breast Cancer Network Germany (BMBC) registry. Results: Compared to symptomatic patients, asymptomatic patients were slightly younger at diagnosis (median age: 55.5 vs. 57.0 years, p = 0.01), had a better performance status at diagnosis (Karnofsky index 80&ndash
Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry—Comparison of Three Different GPA Prognostic Scores
2021
Several scores have been developed in order to estimate the prognosis of patients with brain metastases (BM) by objective criteria. The aim of this analysis was to validate all three published graded-prognostic-assessment (GPA)-scores in a subcohort of 882 breast cancer (BC) patients with BM in the Brain Metastases in the German Breast Cancer (BMBC) registry. The median age at diagnosis of BM was 57 years. All in all, 22.3% of patients (n = 197) had triple-negative, 33.4% (n = 295) luminal A like, 25.1% (n = 221) luminal B/HER2-enriched like and 19.2% (n = 169) HER2 positive like BC. Age ≥60 years, evidence of extracranial metastases (ECM), higher number of BM, triple-negative subtype and l…