Search results for "Propidium"

showing 3 items of 73 documents

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Pol…

2020

The brain, which is a cholesterol-rich organ, can be subject to oxidative stress in a variety of pathophysiological conditions, age-related diseases and some rare pathologies. This can lead to the formation of 7-ketocholesterol (7KC), a toxic derivative of cholesterol mainly produced by auto-oxidation. So, preventing the neuronal toxicity of 7KC is an important issue to avoid brain damage. As there are numerous data in favor of the prevention of neurodegeneration by the Mediterranean diet, this study aimed to evaluate the potential of a series of polyphenols (resveratrol, RSV

eicosapentaenoic acidPharmaceutical ScienceResveratrolDiet Mediterraneanmedicine.disease_causequercetinAnalytical ChemistryMicechemistry.chemical_compound0302 clinical medicineDrug Discoveryoxidative stressKetocholesterolsNeuronschemistry.chemical_classification0303 health sciencesCell Deathfood and beveragesdocosahexaenoic acidEicosapentaenoic acidMitochondriaBiochemistryChemistry (miscellaneous)Docosahexaenoic acid030220 oncology & carcinogenesisMolecular Medicineα-linolenic acidN2a cellsArticlelcsh:QD241-44103 medical and health sciencesresveratrol.lcsh:Organic chemistryCell Line TumorMediterranean dietFatty Acids Omega-3medicineAnimalsPropidium iodidePhysical and Theoretical Chemistry7-ketocholesterol030304 developmental biologyapigeninReactive oxygen speciesOrganic ChemistryNeurotoxicityPolyphenolsmedicine.diseaseOleic acidoleic acidchemistryReactive Oxygen SpeciesOxidative stressMolecules
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Treatment of B-CLL Cells with Bortezomib and Rituximab Reduces Cell Viability In Vitro..

2004

Introduction : In B-CLL, somatic mutation of IgVH genes defines a group of patients with favorable prognosis, whereas the absence of IgVH mutations is correlated with a worse outcome. Our previous data suggested that BCL-6 mutations identify a subgroup of patients with high risk of progression despite the presence of mutated IgVH gene, but the clinical significance of this molecular alteration remains uncertain. New approaches are now being tested for the treatment of B-CLL. Proteasome inhibitor, Bortezomib (Btz), and monoclonal antibodies specific for surface antigens, Rituximab (Rtx), represent potential therapeutic strategy. Objetives : To study the effects of Btz and Rtx on viability of…

medicine.diagnostic_testBortezomibLymphocyteImmunologyCell BiologyHematologyBiochemistryMolecular biologyFlow cytometrychemistry.chemical_compoundmedicine.anatomical_structurechemistryAntigenImmunologymedicineProteasome inhibitorDoubling timePropidium iodideViability assaymedicine.drugBlood
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Erythritol-enriched powder and oral biofilm regrowth on dental implants: an in vitro study.

2021

Background Peri-implant mucositis and peri-implantitis are the main biological complications associated with dental implants. Since most authors agree that bacteria play a major etiological role, the main aims of this study were to determine if a formulation of erythritol and chlorhexidine applied with an air polishing system inhibits biofilm regrowth over dental implants and to compare the decontamination capacity of this therapy with that of mechanical removal by saline and gauze. Material and Methods A multispecies biofilm (P. gingivalis, A. actinomycetemcomitans, F. nucleatum, A. naeslundii, V. parvula and S. oralis) was grown for 14 days on 52 dental implants in an artificial mouth. Th…

medicine.medical_treatmentDentistryComplications (Medicine)Erythritolchemistry.chemical_compoundPropidium monoazidemedicineMucositisHumansimplantoplastytitaniumGeneral DentistrySalineUNESCO:CIENCIAS MÉDICASDental ImplantsbiologyImplants dentalsChemistrybusiness.industryResearchChlorhexidineDental implantsBiofilmAggregatibacter actinomycetemcomitansmedicine.diseasebiology.organism_classificationcompressive strengthPeri-ImplantitisErythritolComplicacions (Medicina)OtorhinolaryngologyBiofilmsSurgeryPowdersbusinessImplantologyBacteriamedicine.drug
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